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Mesnex

Generic Name: mesna (MES-na)
Brand Name: Mesnex

Mesnex is used for:

Preventing or reducing the harmful effects of chemotherapy on the bladder.

Mesnex is an uroprotectant. It works by protecting the bladder wall from the harmful effects of chemotherapy.

Do NOT use Mesnex if:

  • you are allergic to any ingredient in Mesnex or other thiol compounds

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Mesnex:

Some medical conditions may interact with Mesnex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an autoimmune disorder (eg, rheumatoid arthritis, lupus) or kidney problems (eg, nephritis)

Some MEDICINES MAY INTERACT with Mesnex.

However, no specific interactions with Mesnex are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Mesnex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Mesnex:

Use Mesnex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Mesnex is usually administered as an injection at your doctor's office, hospital, or clinic.
  • Drink at least 1 quart (4 cups/1 L) of liquid per day.
  • If you miss a dose of Mesnex, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Mesnex.

Important safety information:

  • Mesnex may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Mesnex. Using Mesnex alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Tell your doctor if your urine turns a pink or red color or if you vomit within 2 hours of taking the oral form of Mesnex.
  • Certain prescription medicines and foods, such as red beets, may also cause your urine to change colors. A lab test of your urine will show if the source of the color is due to one of these causes.
  • Diabetes patients - Mesnex may cause incorrect test results with some urine glucose tests. Check with your doctor before you adjust your dose of your diabetes medicine or change your diet.
  • LAB TESTS, including urine tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Mesnex with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
  • Mesnex should not be used in INFANTS because it contains benzyl alcohol, which may cause serious reactions.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Mesnex, discuss with your doctor the benefits and risks of using Mesnex during pregnancy. It is unknown if Mesnex is excreted in breast milk. Do not breast-feed while taking Mesnex.

Possible side effects of Mesnex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bad taste in mouth; cold symptoms (coughing, sore throat); constipation; diarrhea; dizziness; drowsiness; fever; fluid retention; flushing; headache; loss of appetite; injection site reaction; nausea; pain in arms or legs; paleness; stomach pain; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, face, lips, hands, eyes, face, throat, or tongue); blood in the urine (pink or red urine); chest pain; difficulty swallowing; fast heartbeat; hoarseness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Mesnex:

Mesnex is usually handled and stored by a health care provider. If you are using Mesnex at home, store Mesnex as directed by your pharmacist or health care provider. Keep Mesnex out of the reach of children and away from pets.

General information:

  • If you have any questions about Mesnex, please talk with your doctor, pharmacist, or other health care provider.
  • Mesnex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Mesnex or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Mesnex. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Mesnex. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Mesnex.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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