Luminal

Generic Name: phenobarbital (fee-noe-BAR-bi-tal)
Brand Name: Luminal

Luminal is used for:

The short-term treatment of sleeplessness, the relief of anxiety, tension, and fear, and the treatment of certain types of seizures, especially in emergency situations. It may also be used for other conditions as determined by your doctor.

Luminal is a barbiturate. It works by depressing the central nervous system. This aids you in relaxing and going to sleep.

Do NOT use Luminal if:

  • you are allergic to any ingredient in Luminal
  • you have the blood disorder porphyria
  • you are also taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Flashback: FDA Drug Approvals 2013

Before using Luminal:

Some medical conditions may interact with Luminal. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you suffer from depression, have suicidal tendencies, have a history of substance abuse
  • if you have liver problems or respiratory disease
  • if you have pain or are in shock

Some MEDICINES MAY INTERACT with Luminal. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB), stiripentol, or valproic acid because they may increase the risk of Luminal's side effects
  • Methoxyflurane and the risk of its side effects may be increased by Luminal
  • Beta-adrenergic blockers (eg, propranolol), clozapine, corticosteroids (eg, hydrocortisone), digitoxin, doxycycline, estrogens, imatinib, metronidazole, oral contraceptives (eg, norethindrone/ethinyl estradiol), quinidine, theophyllines, voriconazole, or warfarin because their effectiveness may be decreased by Luminal

This may not be a complete list of all interactions that may occur. Ask your health care provider if Luminal may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Luminal:

Use Luminal as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Luminal is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Luminal at home, a health care provider will teach you how to use it. Be sure you understand how to use Luminal. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Luminal if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Do not suddenly stop using Luminal or change the dose without checking with your doctor.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Luminal, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Luminal.

Important safety information:

  • Luminal may cause drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Luminal with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Luminal; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Luminal. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Use Luminal with caution in the ELDERLY; they may be more sensitive to its effects.
  • Luminal should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Luminal has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Luminal while you are pregnant. Luminal is found in breast milk. If you are or will be breast-feeding while you use Luminal, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, Luminal may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Luminal stops working well. Do not take more than prescribed.

Some people who use Luminal for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Luminal suddenly, you may have WITHDRAWAL symptoms. These may include anxiety, convulsion or seizures, dizziness, increasing weakness, lightheadedness, muscle twitching, nausea, sleeplessness, trembling hands and fingers, unusual visions, vomiting.

Possible side effects of Luminal:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitated mood; clumsiness; confusion; dizziness; excessive daytime drowsiness; headache; injection site reactions; lightheadedness; low blood pressure; nausea; slow heartbeat; slowed breathing; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty breathing; liver damage.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include change in size of pupil; cold, clammy skin; deep sleep; loss of consciousness; slowed or fast breathing.

Proper storage of Luminal:

Store Luminal at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Luminal out of the reach of children and away from pets.

General information:

  • If you have any questions about Luminal, please talk with your doctor, pharmacist, or other health care provider.
  • Luminal is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Luminal or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Luminal. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Luminal. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Luminal.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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