Minoxidil use while Breastfeeding

Drugs containing Minoxidil: Rogaine, Loniten, Hair Regrowth Treatment for Women, Rogaine Women's, Rogaine Men's Extra Strength, Rogaine Extra Strength, Ronoxidil

Minoxidil Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because of the minimal amount of information on this potent agent, use minoxidil with caution, particularly when therapy involves a large dosage or in newborns. Topical minoxidil should pose low risk to the breastfed infant.

Drug Levels

Maternal Levels. In one case report, a 2-month-postpartum mother who was taking minoxidil 5 mg twice daily was given a, oral dose of 7.5 mg. The peak milk level of minoxidil plus glucuronide conjugate was 45.1 mcg/L at 1 hour after the dose. Milk levels paralleled serum levels, falling rapidly after the first hour to a concentration of 12.4 mcg/L at 3 hours, 4 mcg/L at 6 hours, 1.9 mcg/L at 9 hours, 0.8 mcg/L at 12 hours after the dose. [1] Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

No hypertrichosis or other abnormal signs were seen in one infant breastfed for 2 months of maternal minoxidil therapy.[1]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Enalapril, Hydrochlorothiazide, Methyldopa, Propranolol

References

1. Valdivieso A, Valdes G, Spiro TE et al. Minoxidil in breast milk. Ann Intern Med. 1985;102:135. Letter. PMID: 3966734

Minoxidil Identification

Substance Name

Minoxidil

CAS Registry Number

38304-91-5

Drug Class

Antihypertensive Agents

Vasodilator Agents

Administrative Information

LactMed Record Number

184

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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