Eravacycline Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of eravacycline during breastfeeding. The manufacturer states that breastfeeding is not recommended during treatment and for 4 days after the last dose. However, available literature indicates that there is not likely to be harm in short-term use of a eravacycline during lactation because the drug is 79 to 90% bound to plasma proteins, so milk levels are likely low and absorption by the infant is likely inhibited by the calcium in breastmilk. Short-term use of eravacycline acceptable in nursing mothers. If an infant is breastfed, monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. As a theoretical precaution, avoid prolonged or repeat courses during nursing.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Eravacycline
CAS Registry Number
1207283-85-9
Drug Class
Breast Feeding
Lactation
Anti-Infective Agents
Antibacterial Agents
Tetracyclines
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
