I have MDD, GAD and C-PTSD. I am in the middle of a depressive episode, and also in the midst of changing meds. I was taking Effexor XR 75mg and Wellbutrin XL 300mg for a while, but discontinued the Effexor because of side effects ( I weaned off as per my psychiatrist's recommendations). After about a month of terrible withdrawal from the Effexor, I am taking Zoloft along with the Wellbutrin. I was at 25mg for a week and went up to 50mg on April 7th. I've had a couple of really bad days; lots of crying and wanting to die. I was on Zoloft with Wellbutrin before, and only went off then because my GP wanted to try something out on me. So now I'm trying the combo again. Has anyone found Wellbutrin and Zoloft to be a good combination? I am also taking Seroquel 25mg for sleep. My psychiatrist says I'm "covered for depression" with the Wellbutrin, but I am in a depressive episode right now so that can't be true. It's so hard to find the right drug combination! I know you have to give it time, but in the past when I've started a new drug I've usually felt better within a couple of days. Really struggling right now. I feel worthless right now and afraid I'll never be happy again. Any advice would be greatly appreciated.
Do Zoloft and Wellbutrin work well together?
Question posted by CareBear34 on 11 April 2017
Last updated on 13 April 2017
Answers
CareBear34; Yes this is a regular combination taken by many. You can expect some good days and so-so days but remember part of this can still be the Effexor withdrawal's that are breaking through so try to just bear with it. But if it gets to bad call your doctor. Many don't have a clue how long the Effexor and some of the others well stay in the patient's system. so just be careful
Thank you for your comment chuck1957. I always appreciate hearing from you!
I hadn't thought about it still being Effexor withdrawal. Do you think it still would be? My last dose was a little over a month ago. Hmmm. I wonder. If it is then what a terrible drug.
Any time I had started a new drug before I felt better within a few days, which is why I've been discouraged by not feeling better after starting Zoloft again. But maybe that's it. Thank you for your insight!
I have another appointment with my psychiatrist in a few weeks. Hopefully it'll be better by then. I wonder if it would help the anxiety part to decrease the Wellbutrin a bit and increase the Zoloft? Or would that make my depression worse? Zoloft is for depression too though right? So hard to know what to do.
CareBear, Yes it is a good chance still the Effexor and being we are a bit sensitive it does not take much for us to feel things that they swear is out of us. But there is good proof that it can take about as long for some to get it out as it did to get the Effexor level. Please don't count it out.
I won't. Thank you!
Related topics
effexor, effexor xr, wellbutrin, wellbutrin xl, zoloft, depression, post traumatic stress disorder, anxiety, panic disorder, social anxiety disorder, generalized anxiety disorder, major depressive disorder
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