7 Oct 2013
Interactions between your selected drugs
fluoxetine ↔ st. john's wort
Applies to: fluoxetine, st. john's wort
Talk to your doctor before using FLUoxetine together with St. John's wort. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. You should contact your doctor immediately if you experience these symptoms while taking the medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Other drugs that your selected drugs interact with
fluoxetine interacts with more than 500 other drugs.
st. john's wort interacts with more than 300 other drugs.
Interactions between your selected drugs and food
st. john's wort ↔ food
Applies to: st. john's wort
While you are taking St. John's wort, you must not eat or drink certain foods and beverages that are high in tyramine. Eating these foods while you are taking St. John's wort can raise your blood pressure to dangerous levels. This may cause life threatening symptoms such as sudden and severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, seizure (convulsions), and sudden numbness or weakness (especially on one side of the body). Call your doctor at once if you have any of these symptoms. Foods that are high in tyramine include: air dried meats, aged or fermented meats, sausage or salami, pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver, red wine, beer from a tap, beer that has not been pasteurize, aged cheeses, including blue, brick, brie, cheddar, parmesan, romano, and swiss, sauerkraut, over the counter supplements or cough and cold medicines that contain tyramine, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans, or yeast extracts (such as Marmite). Caffeine intake should be limited as well.
- Fluoxetine Information for Consumers
- Fluoxetine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Fluoxetine (detailed)
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SSRIs don't work until taken, regularly, for a while (generally at least two weeks). Is this true for St John's Wort too?
1 answer • 8 Dec 2009
I take 650mg tylenol painkillers and St. John's Wort everyday. Then occasionally I drink beer and energy shots. Is all this safe?
1 answer • 3 Apr 2012
St. John's Wort - I need to take a break every so often or the effectiveness wears off. Experiences?
... or Insights?
1 answer • 3 Dec 2014