What is the difference of Hydrocortisone and Fludrocortisone?

Question is Closed Report Mark as Favorite

Answers (1)

3 Oct 2009

Hydrocortisone and Fludrocortisone are both corticosteroids.

Hydrocortisone has more glucocorticoid activity, which has more anti-inflammatory effects.

Fludrocortisone has more mineralocorticoid actvity, which is needed to keep a balance of water and electrolytes, hence also helps keep blood pressure in balance.

This is just a brief explanation - if you would like more information please add a comment and I'll try and elaborate.

Votes: +0
silverheelsbell 20 Mar 2010

I was also wondering about the difference between these two meds so I hope you don't mind me jumping in your conversation.

Do you think then that Fludrocortisone may cause less weight-gain than Hydrocortisone?

Also, would Fludrocortisone be as effective as Hydrocortisone in treating Congenital adrenal hyperplasia (CAH)?

RonPalmerInSD 27 Oct 2010

1. How much corticosteroid activity is in fludrocortisone compared to hydrocortisone?

2. I wonder if added fludrocortisone might allow the cut back of some of my hydrocortisone to keep it from getting too high?

3. Also, my doctor has prescribed 5mg of hydrocortisone at bedtime to keep my own cortisol from waking me too early. But it doesn't last long enough. Could fludrocortisone do this job and last a little longer?

Thank you for helping me to learn about these possibilities.

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar questions

Hydrocortisone - my stool has turned black. Is this normal?

I'm using the Hydrocortisone Acetate Suppositories 25 mg

1 answer 11 Apr 2012

Why hydrocortisone cream is present in 2 dosage strength?

what is the effect of the difference doses of hydrocortisone cream in absorption?

1 answer 26 Jan 2013

Can I use Hydrocortisone Cream 2.5% on my scalp?

I have a dry scaling scalp condition that is spreading slowly. I treated a similar condition on chin caused by combing my beard and scratching the ...

1 answer 28 Sep 2013