4 Apr 2010
Opioid agonists bind to the opioid receptors and provide pain relief. Morphine is a pure opioid agonist whose principal therapeutic action is analgesia. Other members of the class known as opioid agonists include substances such as oxycodone, hydromorphone, fentanyl, codeine, and hydrocodone. Pharmacological effects of opioid agonists include anxiolysis, euphoria, feelings of relaxation, respiratory depression, constipation, miosis, cough suppression, and analgesia. Like all pure opioid agonist analgesics, with increasing doses there is increasing analgesia, unlike with mixed agonist/antagonists or non-opioid analgesics, where there is a limit to the analgesic effect with increasing doses. With pure opioid agonist analgesics, there is no defined maximum dose; the ceiling to analgesic effectiveness is imposed only by side effects, the more serious which may include somnolence and respiratory depression.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
In the post, http://www.drugs.com/dosage/hydromorphone.html, there is mention to consider decreasing the IV dose of Dilaudid in the elderly. ...
1 answer • 4 May 2011
High opioid tolerance and metabolism. Wrenched my lower back in motorcycle accident five years ago. At this juncture Nucynta ER at 500mg 3X daily ...
2 answers • 21 Aug 2014
... opioid nor an NSAID, and I can't find anything about it online
1 answer • 2 days 20 hours ago