Can taking too much water with losartan potassium and hydrochlorothiazide tablet effect you?

Richard; I really doubt it unless you are for some reason on a low water diet. But you would have to drink a lot of water to flush this medication out of your system. But it would not hurt to cut down a bit on your water. You should not feel sick of uncomfortable because of your water intake. And you should ask your doctor the next time your in if it is bothering you have a good day.