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Related terms: Acute Bacterial Cystitis, Catheter-Associated Urinary Tract Infection (UTI), Chronic Urinary Tract Infection (UTI), Cystitis, acute bacterial, Infection, Urinary Tract, UTI, Catheter-Associated Urinary Tract Infection, Chronic Urinary Tract Infection, Urinary Infection

Improper Antibiotic Use Often Due to Misdiagnosis: Study

Posted 20 May 2015 by Drugs.com

WEDNESDAY, May 20, 2015 – Misdiagnosis often leads to improper antibiotic use in hospitals, new research finds. Incorrect antibiotic use can cause patient harm, reduce the effectiveness of antibiotics and increase health care costs, the researchers noted. "Antibiotic therapies are used for approximately 56 percent of inpatients in U.S. hospitals, but are found to be inappropriate in nearly half of these cases, and many of these failures are connected with inaccurate diagnoses," study author Dr. Greg Filice said in a news release from the Society for Healthcare Epidemiology of America. Filice, an internist with the Minneapolis Veterans Affairs Health Care System, and his colleagues analyzed 500 inpatient cases at the Minneapolis VA Medical Center. They found that inappropriate use of antibiotics occurred with 95 percent of patients who received an incorrect or indeterminate diagnosis, ... Read more

Related support groups: Urinary Tract Infection, Metronidazole, Bactrim, Bladder Infection, Pneumonia, Flagyl, Bactrim DS, Kidney Infections, Polymyxin B, Xifaxan, Septra, Zyvox, Rifaximin, Sulfamethoxazole/Trimethoprim, Sepsis, Bacitracin, Metro, Septra DS, Cotrimoxazole, Chloramphenicol

FDA Medwatch Alert: Zerbaxa (ceftolozane and tazobactam): Drug Safety Communication - FDA Cautions about Dose Confusion and Medication Errors

Posted 20 May 2015 by Drugs.com

ISSUE: The U.S. Food and Drug Administration (FDA) is warning health care professionals about the risk for dosing errors with the antibacterial drug Zerbaxa (ceftolozane and tazobactam) due to confusion about the drug strength displayed on the vialand carton labeling. (See the Drug Safety Communication for Label Photos). FDA evaluated seven reported cases of medication error that occurred during preparation of the dose in the pharmacy due to confusion with the display of the strength of individual ingredients on Zerbaxa’s vial labels and carton labeling. Listing the individual drug strengths led to confusion because it was different from labeling for other drugs in the beta-lactam/beta-lactamase class that express strength as the sum of the two active ingredients. In some cases, this led to administration of 50% more drug than was prescribed. No adverse events were reported among these s ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection, Ceftolozane/tazobactam, Zerbaxa

Health Tip: Spotting Signs of Urinary Tract Infection

Posted 1 May 2015 by Drugs.com

-- A urinary tract infection (UTI) occurs when bacteria become prolific in the bladder, kidneys or elsewhere in the urinary tract. The National Kidney and Urologic Diseases Information Clearinghouse says symptoms of UTI may include: A burning sensation during urination. The frequent need to urinate, though often passing little urine. Pain in the side below the ribs or in the back. Bloody or cloudy urine that may have a bad odor. Chills or fever. Read more

Related support groups: Urinary Tract Infection, Bladder Infection, Kidney Infections, Urinary Alkalinization, Pyelonephritis

Study Casts Doubt on Use of Common Antibiotic for UTIs in Women

Posted 30 Apr 2015 by Drugs.com

THURSDAY, April 30, 2015 – The antibiotic most commonly prescribed for bladder and other urinary tract infections, nitrofurantoin, may not be the most effective option, new research suggests. More than 25 percent of older adults have reduced kidney function, and bladder infections are a common complaint. Doctors often turn to nitrofurantoin to treat these and other urinary tract infections (UTIs), but concerns have been raised about the ability of the drug to reach the urinary tract and target bacteria that causes bladder infections, especially in those with poor kidney function. The new Canadian research was led by Dr. Amit Garg, a nephrologist at Western University in London, Ontario. His team compared the benefits of nitrofurantoin to the effectiveness of other commonly used antibiotics such as ciprofloxacin ("Cipro") and norfloxicin. The study, published recently in the Canadian ... Read more

Related support groups: Urinary Tract Infection, Metronidazole, Bactrim, Bladder Infection, Cipro, Ciprofloxacin, Levaquin, Flagyl, Nitrofurantoin, Macrobid, Bactrim DS, Levofloxacin, Kidney Infections, Avelox, Polymyxin B, Xifaxan, Septra, Macrodantin, Zyvox, Sulfamethoxazole/Trimethoprim

New Antibiotic Avycaz Approved

Posted 26 Feb 2015 by Drugs.com

THURSDAY, Feb. 26, 2015 – The combination antibiotic Avycaz (ceftazidime-avibactam) has been approved by the U.S. Food and Drug Administration to treat adults with complicated infections of the intra-abdominal area or urinary tract, including the kidneys. Avycaz contains the previously approved antibiotic ceftazidime, and the newer antibacterial drug avibactam, the agency said in a news release. Approved to help combat antibacterial resistance, Avycaz is sanctioned for people who have limited or no other treatment options, the FDA said. The most common side effects identified during clinical testing included vomiting, nausea, constipation and anxiety. Users with poor kidney function had more serious adverse reactions including decreased effectiveness and seizures, the agency said. And users allergic to penicillin may be at greater risk of serious skin reactions and anaphylaxis, the FDA ... Read more

Related support groups: Urinary Tract Infection, Kidney Infections, Intraabdominal Infection, Pyelonephritis

FDA Approves Avycaz (ceftazidime and avibactam) for Complicated Abdominal and Urinary Tract Infections

Posted 25 Feb 2015 by Drugs.com

February 25, 2015 – The U.S. Food and Drug Administration today approved Avycaz (ceftazidime-avibactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI), in combination with metronidazole, and complicated urinary tract infections (cUTI), including kidney infections (pyelonephritis), who have limited or no alternative treatment options. Avycaz contains two drugs: ceftazidime, a previously approved cephalosporin antibacterial drug, and avibactam, to help extend bacterial resistance. “The FDA is committed to making therapies available to treat patients with unmet medical need,” said Edward Cox, M.D., M.P.H, director of the Office of Antimicrobial Products in the FDA’s Center for Drug Evaluation and Research. “It is important that the use of Avycaz be reserved to situations when there are limited or no alternative antibacterial drugs fo ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

Health Tip: Help Prevent Urinary Tract Infections Among Children

Posted 27 Jan 2015 by Drugs.com

-- There are things parents can do to help prevent urinary tract infections among children. The National Kidney and Urologic Diseases Information Clearinghouse offers these suggestions: Encourage your child to use the bathroom regularly. If your child doesn't urinate frequently, offer more fluids. Make sure your child knows how to properly wipe after using the bathroom. Dress your child in cotton underwear and loosely fitted clothing. Read more

Related support groups: Urinary Tract Infection

Combination Antibiotic Zerbaxa Approved

Posted 22 Dec 2014 by Drugs.com

MONDAY, Dec. 22, 2014 – The combination antibiotic Zerbaxa (ceftolozane/tazobactam) has been approved by the U.S. Food and Drug Administration to treat adults with complicated abdominal infections and complicated urinary tract infections. The approval for abdominal infections was approved in combination with another drug, metronidazole, the agency said in news release. The approval for urinary tract infection includes infection of the kidney. Zerbaxa is the fourth antibiotic to be FDA-approved in 2014, following approval of Dalvance (dalbavancin), Sivextro (tedizolid) and Orbactiv (oritavancin). The drug's label includes a warning about decreased effectiveness among people with kidney impairment, the FDA said. The most common side effects reported during clinical testing included nausea, diarrhea, headache and fever. Zerbaxa is marketed by Cubist Pharmaceuticals, based in Lexington, ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

FDA Approves Zerbaxa (ceftolozane/tazobactam) for Complicated Intra-Abdominal/Urinary Tract Infections

Posted 19 Dec 2014 by Drugs.com

December 19, 2014 – The U.S. Food and Drug Administration today approved Zerbaxa (ceftolozane/tazobactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI). Zerbaxa is a combination product containing ceftolozane, a cephalosporin antibacterial drug, and tazobactam, a beta-lactamase inhibitor. Zerbaxa is used to treat cUTI, including kidney infection (pyelonephritis). It is used in combination with metronidazole to treat cIAI. Zerbaxa is the fourth new antibacterial drug approved by the FDA this year. The agency approved Dalvance (dalbavancin) in May, Sivextro (tedizolid) in June and Orbactiv (oritavancin) in August. “The FDA approval of several new antibacterial drugs this year demonstrates the agency’s commitment to increasing the availability of treatment options for patients and phy ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

Childhood Urinary Tract Infection May Bring Lasting Harm to Kidneys

Posted 6 Aug 2014 by Drugs.com

TUESDAY, Aug. 5, 2014 – Urinary tract infections are the most common serious bacterial infections in young children, and almost one of every eight kids who gets one will end up with scarring on the kidneys and an increased risk of kidney failure later in life. Identifying those kids early is critical, and researchers now report that a combination of three factors – high fever, detection of kidney abnormalities via ultrasound and identification of the type of bacteria involved – spots such patients as accurately as a very unpleasant catheter-based test does. "We found that you more or less can predict the children who are at higher risk by looking at three different things when they come in," said study author Dr. Nader Shaikh, an assistant professor at the University of Pittsburgh and a pediatrician at the Children's Hospital of Pittsburgh. In the past, doctors used a combination ... Read more

Related support groups: Urinary Tract Infection

'Sterile' Urine May Be a Myth

Posted 19 May 2014 by Drugs.com

MONDAY, May 19, 2014 – Many people have heard that human urine is devoid of germs, but a new study seems to question that idea. "Doctors have been trained to believe that urine is germ-free," Dr. Linda Brubaker, dean of Loyola University Chicago Stritch School of Medicine, said in a university news release. "These findings challenge this notion." Brubaker's team analyzed urine samples from 90 women. It found bacteria both in the urine of healthy women as well as the urine of women with overactive bladder. However, the germs were different between the two groups, the researchers said. "The presence of certain bacteria in women with overactive bladder may contribute to overactive bladder symptoms," lead investigator Evann Hilt, a second-year master's student, theorized in the news release. But only more study can confirm whether those bacterial differences are "clinically relevant for ... Read more

Related support groups: Urinary Tract Infection

Urine Tests Don't Always Confirm Urinary Infections, Study Finds

Posted 13 Nov 2013 by Drugs.com

WEDNESDAY, Nov. 13 – When doctors suspect a patient has a urinary tract infection, they often request a urine sample so they can test for the presence of bacteria. Now, new research suggests this step may be unnecessary. Nearly one-quarter of women who had signs of a urinary tract infection – a burning feeling when urinating or feeling an urgent need to pee – had no evidence of bacteria in their urine or in their bladders, the study found. And although a number of urine culture tests found a variety of different bacteria, only one bug – Escherichia coli – was found in both the urine test and the bladder. These findings suggest that today's lab tests may not be refined enough to detect very small quantities of bacteria in the bladder. It's also possible that the symptoms may not be caused by a bladder infection, but instead may be caused by an infection in the urethra, the tube that ... Read more

Related support groups: Urinary Tract Infection

Urinary Tract Infection Often Puts Older Men in Hospital

Posted 18 Oct 2013 by Drugs.com

FRIDAY, Oct. 18 – Although urinary tract infections (UTIs) are much more common among women, older men who develop the condition are more likely to be hospitalized as a result, researchers have found. In addition, the urologists from Henry Ford Hospital pointed out that health care costs are 10 times higher when patients with UTIs need to be admitted to the hospital for treatment. They concluded that being able to predict which patients are most likely to be hospitalized could reduce these medical expenses. "We found that those patients who were hospitalized for treatment of urinary tract infections were most often older men, as well as those with serious kidney infections. They were also more likely to be seen at urban teaching hospitals, and/or treated in ZIP codes with higher median incomes," the study's lead author, Dr. Jesse Sammon, a researcher at Henry Ford's Vattikuti Urology ... Read more

Related support groups: Urinary Tract Infection

How Estrogen May Help Prevent Urinary Tract Infections After Menopause

Posted 20 Jun 2013 by Drugs.com

THURSDAY, June 20 – Estrogen treatment delivered vaginally may help prevent repeat urinary tract infections in postmenopausal women, new laboratory research suggests. Urinary tract infections are common among women, with one-quarter experiencing recurring infections. And age-related changes increase the likelihood of these infections developing after menopause, when estrogen production plummets. Until now, taking antibiotics prophylactically – to ward off recurrent urinary tract infections – has been the gold standard for these women, said Thomas Hannan, a research instructor in pathology and immunology at Washington University School of Medicine in St. Louis. "But antibiotic resistance is increasing, and some women are resistant to everything we have," Hannan said. "We need other options. We need non-antibiotic options." This study, published in the June 19 issue of the journal ... Read more

Related support groups: Urinary Tract Infection, Postmenopausal Symptoms, Vagifem, Estrace Vaginal Cream, Estring, Premarin Vaginal, Ogen Vaginal Cream, Dienestrol, Ortho Dienestrol

Can You Skip Antibiotics for Urinary Tract Infection?

Posted 4 Jun 2013 by Drugs.com

TUESDAY, June 4 – Some women with symptoms of a urinary tract infection may be able to skip the antibiotics typically prescribed and have their symptoms improve or clear, according to a new Dutch study. "In healthy people, many mild infections can be cured spontaneously," said study leader Dr. Bart Knottnerus, a researcher at the Academic Medical Center of the University of Amsterdam. A U.S. expert, however, had a number of cautions about the findings, including the small number of women studied. For the research, published May 31 in the journal BMC Family Practice, Knottnerus recruited women from 20 general medical practices in and around the Netherlands from 2006 to 2008. Women who had contacted their doctor complaining of frequent urination, painful urination or both were asked if they would be willing to delay antibiotics – but only if their symptoms had been present for no longer ... Read more

Related support groups: Urinary Tract Infection, Bladder Infection, Kidney Infections, Prevention of Bladder infection, Cystitis Prophylaxis, Pyelonephritis

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