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Rheumatoid Arthritis Blog

Related terms: Arthritis, Arthritis, Rheumatoid, RA, Rheumatoid

FDA Approves Rasuvo (methotrexate) Injection

Posted 11 days ago by Drugs.com

Chicago, IL, July 14, 2014 – Medac Pharma, Inc., a privately held pharmaceutical company focused on the development of new molecules and improving the effectiveness of existing medicines, announced that the U.S. Food and Drug Administration (FDA) has approved Rasuvo, a subcutaneous injectable methotrexate (MTX) therapy delivered in an auto-injector for rheumatoid arthritis (RA), polyarticular-course juvenile idiopathic arthritis (pJIA) and psoriasis. Rasuvo will be available in 10 dosage strengths, ranging from 7.5 mg to 30 mg in 2.5 mg increments and will be launched in the U.S. The company concurrently announced that the U.S. District Court for the District of Delaware has denied a motion for a preliminary injunction filed by Antares Pharma, Inc. “We’re delighted to have secured approval for our lead product, Rasuvo, and look forward to introducing this much-needed therapy to the ma ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Psoriasis, Juvenile Idiopathic Arthritis

Health Tip: Managing Arthritis-Related Fatigue

Posted 9 May 2014 by Drugs.com

-- Fatigue can be a significant problem for people with arthritis, but there are things you can do to help manage your symptoms. The Arthritis Foundation offers these suggestions: Adjust your schedule to accommodate symptoms, such as starting chores after morning fatigue, pain and stiffness have eased. Eat lighter and more frequent meals. Get regular, moderate exercise and make time to get plenty of rest. Learn to prioritize, and do the important things first. Put off what you don't have the energy to do. Don't be shy about asking others to help when necessary. Read more

Related support groups: Rheumatoid Arthritis, Osteoarthritis, Fatigue

Could a Few Beers a Week Cut a Woman's Rheumatoid Arthritis Risk?

Posted 7 May 2014 by Drugs.com

WEDNESDAY, May 7, 2014 – Having a beer a few times a week might help women avoid painful rheumatoid arthritis, a new study suggests. The disease, which affects women more than men, is a form of arthritis linked to immune system dysfunction. According to the Arthritis Foundation, over 1.5 million Americans suffer from the disease, which typically begins in the 20s or 30s. However, "long-term, moderate alcohol drinking may reduce future rheumatoid arthritis development" in women, said lead researcher Dr. Bing Lu, an assistant professor of medicine at Brigham and Women's Hospital and Harvard Medical School, in Boston. Overall, moderate use of any form of alcohol reduced the risk by about 21 percent, but moderate beer drinking – two to four beers per week – cut women's odds for the disease by nearly a third, the study found. The findings are published in the spring 2014 issue of ... Read more

Related support groups: Rheumatoid Arthritis

Rheumatoid Arthritis May Harm Kidneys

Posted 14 Apr 2014 by Drugs.com

FRIDAY, April 11, 2014 – People with rheumatoid arthritis may be at increased risk for kidney disease and require close monitoring, a new study suggests. Researchers looked at 813 people with rheumatoid arthritis and an equal number of people without the condition. Over 20 years, the rheumatoid arthritis patients had a 25 percent risk of developing chronic kidney disease, compared with a 20 percent risk for those in the general population. "That might not seem like a lot, but in fact that's quite a big difference, and it has important implications for the course of rheumatoid arthritis and for the management of the disease," study senior author Dr. Eric Matteson, chair of rheumatology at the Mayo Clinic in Rochester, Minn., said in a Mayo news release. Factors that contribute to a higher risk of kidney disease in rheumatoid arthritis patients include more severe inflammation in the ... Read more

Related support groups: Rheumatoid Arthritis, Chronic Kidney Disease

Groundbreaking Partnership Formed to Develop New Treatments

Posted 4 Feb 2014 by Drugs.com

TUESDAY, Feb. 4, 2014 – In a first-of-its-kind initiative, the U.S. National Institutes of Health has partnered with 10 drug companies and several nonprofit groups to speed development of biological ways of diagnosing and treating common chronic diseases. The first diseases targeted by the Accelerating Medicines Partnership are Alzheimer's, type 2 diabetes and two autoimmune disorders, rheumatoid arthritis and lupus. The partnership will invest more than $230 million over five years on these initial projects. The data and analyses that result will be made available to all biomedical researchers, the NIH said. "Patients and their caregivers are relying on science to find better and faster ways to detect and treat disease and improve their quality of life," NIH director Dr. Francis Collins said in an agency news release. "Currently, we are investing a great deal of money and time in ... Read more

Related support groups: Diabetes, Type 2, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Alzheimer's Disease, Lupus Erythematosus, Autoimmune Hepatitis

Shoulder Replacement May Help for Severe Rheumatoid Arthritis

Posted 30 Jan 2014 by Drugs.com

THURSDAY, Jan. 30, 2014 – Although hip and knee replacements are common, a similar surgery to replace diseased shoulder joints also appears worthwhile for rheumatoid arthritis patients whose severe shoulder pain and stiffness can't be eased by medication or physical therapy, new research suggests. Scientists from the Mayo Clinic found that 93 percent of rheumatoid arthritis patients who underwent a total shoulder replacement – in which both sides of a shoulder joint are replaced – needed no further surgery on the joint a decade later. The same was true for 88 percent of those undergoing a partial shoulder replacement. "We were most happy to see the consistency of pain relief and improvement of function among patients," said study author Dr. John Sperling, an orthopedic surgeon at the clinic in Rochester, Minn. "Shoulder replacement has come a long way over the past 20 to 25 years. ... Read more

Related support groups: Rheumatoid Arthritis

Breast-Feeding Might Reduce Moms' Odds of Rheumatoid Arthritis

Posted 7 Jan 2014 by Drugs.com

TUESDAY, Jan. 7, 2014 – Women who breast-feed may have a lower risk of developing rheumatoid arthritis later in life, new research suggests. Researchers analyzed data from more than 7,300 women, aged 50 and older, in China who completed questionnaires that asked about their health and lifestyle, including whether they breast-fed or used birth control pills. Most of the women had at least one child, and more than 95 percent of those with children had breast-fed for at least a month. Only 11 percent used birth control pills, and mostly for only a short time. The average age for their first pregnancy was 24, and the average age at diagnosis of rheumatoid arthritis was just shy of 48. Women who breast-fed were about half as likely to develop rheumatoid arthritis as those who never breast-fed. And the longer a woman breast-fed, the lower her risk of developing rheumatoid arthritis, ... Read more

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Rheumatoid Arthritis Patients See Big Boost in Quality of Life

Posted 3 Dec 2013 by Drugs.com

TUESDAY, Dec. 3, 2013 – Rheumatoid arthritis patients can generally look forward to a much better quality of life today than they did 20 years ago, new research suggests. The observation is based on a comparative multi-year tracking of more than 1,100 rheumatoid arthritis patients. All had been diagnosed with the often severely debilitating autoimmune disease at some point between 1990 and 2011. The reason for the brighter outlook: a combination of better drugs, better exercise and mental health therapies, and a greater effort by clinicians to boost patient spirits while encouraging continued physical activity. "Nowadays, besides research on new drug [treatments], research is mainly focused on examining which treatment works best for which patient, so therapy can become more 'tailor-made' and therefore be more effective for the individual patient," said Cecile Overman, the study's lead ... Read more

Related support groups: Rheumatoid Arthritis

10 Percent of U.S. Adults Physically Limited by Arthritis: CDC

Posted 7 Nov 2013 by Drugs.com

THURSDAY, Nov. 7 – More than 50 million Americans have arthritis, and almost half of them can't perform normal daily activities because of the disease, U.S. health officials said Thursday. Aging and obesity are the chief culprits behind this growing health problem, according to the U.S. Centers for Disease Control and Prevention. "The increase in arthritis definitely has to do with the aging of our population, but it's also potentially linked to the obesity epidemic," said the study's lead author, CDC epidemiologist Kamil Barbour. The report, published in the Nov. 8 issue of the CDC's Morbidity and Mortality Weekly Report, is based on data from the 2010-2012 National Health Interview Survey. The researchers found that almost one-quarter of U.S. adults – or 52.5 million – have some form of arthritis. And the disease limits mobility for almost 10 percent of adults – 22.7 million. ... Read more

Related support groups: Rheumatoid Arthritis, Osteoarthritis

Certain Rheumatoid Arthritis Drugs May Also Protect Patients' Hearts, Studies Find

Posted 27 Oct 2013 by Drugs.com

SATURDAY, Oct. 26 – Drugs that people with rheumatoid arthritis use to help ease the symptoms of the disease might also help ward off heart trouble, two new studies find. Researchers in Sweden found that so-called "biologic" drugs, known as tumor necrosis factor inhibitors, or anti-TNFs, slightly reduce the risk for acute coronary syndrome – a condition that includes angina and heart attack in which blood supply to the heart muscle is suddenly blocked. In another study, British scientists also found taking these drugs was associated with a lower risk for heart attack in patients with rheumatoid arthritis. The findings were to be presented Saturday at the American College of Rheumatology's annual meeting in San Diego. Findings presented at medical meetings are typically considered preliminary until published in a peer-reviewed journal. The roughly 1.3 million Americans affected by the ... Read more

Related support groups: Rheumatoid Arthritis, Humira, Enbrel, Remicade, Cimzia, Simponi, Infliximab, Etanercept, Adalimumab, Golimumab, Certolizumab

Treating Rheumatoid Arthritis Early May Cut Damaging Effects

Posted 27 Oct 2013 by Drugs.com

SATURDAY, Oct. 26 – Immediate and effective treatment for rheumatoid arthritis reduces the risk that patients will have joint damage and disability within a few years, a new study suggests. The findings show the need for doctors to discourage patients from delaying treatment, according to the researchers at the Hospital for Special Surgery in New York City. "We need to educate people diagnosed with rheumatoid arthritis about this. Some want to delay treatment because they are afraid. They haven't wrapped their heads around the fact that they have this disease, or they are reluctant to start taking medication. Some resort to non-medicinal approaches, many of which have limited effect," study lead investigator and rheumatologist Dr. Vivian Bykerk said in a hospital news release. "Unfortunately, I have seen too many people delay effective treatment approaches and they come back a year ... Read more

Related support groups: Rheumatoid Arthritis

Otrexup (Methotrexate) Injection Approved By FDA

Posted 15 Oct 2013 by Drugs.com

EWING, N.J., October 14, 2013 — Antares Pharma, Inc. today announced the approval of Otrexup (methotrexate) injection by the U.S. Food and Drug Administration (FDA). Otrexup is the first FDA approved subcutaneous (SC) methotrexate (MTX) for once weekly self-administration with an easy-to-use, single dose, disposable auto injector. Otrexup is indicated for adults with severe active rheumatoid arthritis (RA) who have had an insufficient therapeutic response to or are intolerant of an adequate trial of first line therapy including full dose non-steroidal anti-inflammatory agents (NSAIDs), or children with active polyarticular juvenile idiopathic arthritis (pJIA). The FDA also approved adult use of Otrexup for symptomatic control of severe recalcitrant, disabling psoriasis that is not adequately responsive to other forms of therapy. In 2012, approximately six million prescriptions were w ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Psoriasis, Juvenile Rheumatoid Arthritis, Juvenile Idiopathic Arthritis

Rheumatoid Arthritis Increases Potential for Blood Clots, Study Suggests

Posted 8 Aug 2013 by Drugs.com

THURSDAY, Aug. 8 – Rheumatoid arthritis increases the risk of developing potentially fatal blood clots in the legs and lungs, according to new research from Taiwan. People with this inflammatory form of arthritis are more than three times as likely to develop a deep vein thrombosis (a clot usually in the legs) and twice as likely to have a pulmonary thromboembolism (a clot that travels to the lungs) compared to those without the diagnosis, the new study found. "I would call this a moderate increased risk," said Dr. Tore Kvien, editor-in-chief of the journal Annals of the Rheumatic Diseases and head of rheumatology at Diakonhjemmet Hospital in Oslo, Norway. The research was published online Aug. 7 in the journal. The study – which found an association between rheumatoid arthritis and blood clots, but not a direct cause-and-effect relationship – is the latest of several examining this ... Read more

Related support groups: Rheumatoid Arthritis

Simponi Aria (golimumab) for Infusion Receives FDA Approval for Treatment of Moderately to Severely Active Rheumatoid Arthritis

Posted 19 Jul 2013 by Drugs.com

First Anti-TNF Infusion Therapy Approved in More Than a Decade for Patients Living with Moderately to Severely Active Rheumatoid Arthritis HORSHAM, Pa., July 18, 2013 /PRNewswire/ – Janssen Biotech, Inc. announced today the U.S. Food and Drug Administration (FDA) approval of SIMPONI® ARIA TM (golimumab) for infusion for the treatment of adults with moderately to severely active rheumatoid arthritis (RA) in combination with  methotrexate.  SIMPONI ARIA, the only fully-human anti-tumor necrosis factor (TNF)-alpha infusible therapy, has been shown to significantly improve signs and symptoms and physical function, and inhibit the progression of structural damage.  The SIMPONI ARIA dose regimen is 2 mg/kg given as an intravenous infusion at weeks 0 and 4, then every 8 weeks thereafter. The infusion is given over a 30-minute period, providing a short infusion time for pat ... Read more

Related support groups: Rheumatoid Arthritis, Simponi, Golimumab

Expensive or Not, Rheumatoid Arthritis Drugs Have Similar Effect: Study

Posted 1 Jul 2013 by Drugs.com

MONDAY, July 1 – Treatment with a pricey biological drug was no better than cheaper, conventional therapy in terms of reducing time off from work for people with rheumatoid arthritis, a new study finds. Swedish researchers assessed lost work days among rheumatoid arthritis patients who had not responded to initial treatment with a standard medication, methotrexate. The group of 204 patients were randomly given either the biological drug infliximab (Remicade) or conventional combination therapy with the non-biologics sulfasalazine plus hydroxychloroquine. At the start of the study, the average amount of lost work time was 17 days per month for all patients. During the 21-month study, the patients receiving conventional therapy lost about six fewer days of work per month, compared with about five fewer days for those taking Remicade – not a significant difference. Regardless of the ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Remicade, Plaquenil, Hydroxychloroquine, Sulfasalazine, Infliximab, Azulfidine, Sulfazine, Trexall, Methotrexate LPF Sodium, Rheumatrex Dose Pack, Azulfidine EN-tabs, Plaquenil Sulfate, Folex PFS, Quineprox

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