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Drugs May Help Relieve Restless Legs Syndrome

Posted 4 Mar 2013 by Drugs.com

MONDAY, March 4 – People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms. The medications, which include Requip (ropinirole), levodopa, Neurontin (gabapentin) and Lyrica (pregabalin), appear to reduce symptoms of the syndrome in more than 60 percent of patients, researchers report. The first two drugs raise dopamine levels in the body, and the last two drugs reduce the amount of calcium reaching brain cells and trigger the production of other chemicals that help reduce pain. Dopamine is a brain chemical that regulates movement and mood. "Physicians and patients now have better information on the effectiveness and harms of two types of drug treatments for patients with at least moderately severe restless legs symptoms in which to guide treatment choices," said review author Dr. Timothy Wilt, ... Read more

Related support groups: Gabapentin, Lyrica, Neurontin, Restless Legs Syndrome, Requip, Pregabalin, Ropinirole, Levodopa, Gralise, Horizant, Requip XL, Requip Starter Kit, Gabarone, Repreve, Dopar, ReQuip Starter Pack, Larodopa, Fanatrex, ReQuip Follow on Pack

FDA Medwatch Alert: Risperidone (Risperdal) and Ropinirole (Requip): Medication Errors - Name Confusion

Posted 14 Jun 2011 by Drugs.com

ISSUE: FDA notified healthcare professionals and the public of medication error reports in which patients were given risperidone (Risperdal) instead of ropinirole (Requip) and vice versa. In some cases, patients who took the wrong medication needed to be hospitalized. The FDA determined that the factors contributing to the confusion between the two products include: Similarities of both the brand (proprietary) and generic (established) names Similarities of the container labels and carton packaging Illegible handwriting on prescriptions Overlapping product characteristics, such as the drug strengths, dosage forms, and dosing intervals. BACKGROUND: Risperidone (Risperdal) is an antipsychotic medication used to treat mental illnesses including schizophrenia, bipolar disorder, and irritability associated with autistic disorder. Ropinirole (Requip) is a dopamine agonist used in the ... Read more

Related support groups: Risperdal, Risperidone, Requip, Ropinirole, Requip XL, Risperdal Consta, Risperdal M-Tab, Repreve, Requip Starter Kit, ReQuip Follow on Pack, ReQuip Starter Pack

Parkinson's Drugs Linked to Behavior Problems in Study

Posted 30 Mar 2011 by Drugs.com

TUESDAY, March 29 – Parkinson's disease drugs called dopamine agonists appear to cause impulse control problems in almost one-quarter of patients, says a new study. Previous research has linked dopamine agonists, which include Mirapex (pramipexole) and Requip (ropinirole), to impulse control disorders, such as gambling addiction and hypersexuality, and to compulsive behaviors, such as binge eating, overspending and excessive computer use. In this study, Mayo Clinic researchers analyzed Parkinson's disease patient records over two years. "What we found was that as many as 22 percent of patients during that two-year period had a new-onset impulse control disorder," lead investigator and neurology fellow Dr. Anhar Hassan said in a Mayo Clinic news release. The higher the dose of dopamine agonist, the more likely a patient was to develop an impulse control disorder, the researchers found. ... Read more

Related support groups: Parkinson's Disease, Mirapex, Requip, Sinemet, Ropinirole, Emsam, Azilect, Pramipexole, Levodopa, Bromocriptine, Carbidopa, Cabergoline, Selegiline, Amantadine, Parlodel, Neupro, Dostinex, Stalevo, Requip XL, Carbidopa/Levodopa

Parkinson's Drugs Tied to Compulsive Behaviors

Posted 10 May 2010 by Drugs.com

MONDAY, May 10 – Medicines used to treat Parkinson's disease may increase the risk of impulse control disorders, such as problem gambling, compulsive shopping and binge eating, researchers warn. In a new study that included 3,090 patients being treated for Parkinson's at 46 movement disorder centers in the United States and Canada, the researchers found that 13.6 percent of the patients had impulse control disorders. These impulse disorders included gambling (5 percent), compulsive sexual behavior (3.5 percent), compulsive shopping (5.7 percent) and binge eating (4.3 percent), and nearly 4 percent of the patients had two or more of these disorders. Impulse control disorders were more common among patients taking dopamine agonist medications (17.1 percent) than in those not taking the drugs (6.9 percent), the study authors found. Other factors associated with impulse control disorders ... Read more

Related support groups: Parkinson's Disease, Mirapex, Requip, Sinemet, Ropinirole, Emsam, Azilect, Pramipexole, Levodopa, Bromocriptine, Carbidopa, Cabergoline, Selegiline, Amantadine, Parlodel, Neupro, Dostinex, Stalevo, Requip XL, Carbidopa/Levodopa

Cutting Parkinson's Drug Dose Linked to Withdrawal Effects

Posted 14 Jan 2010 by Drugs.com

WEDNESDAY, Jan. 13 – Reduced dosages of dopamine agonists, drugs routinely used to treat Parkinson's disease, can cause symptoms similar to those experienced by addicts in withdrawal, such as anxiety, panic attacks, pain, dizziness and drug cravings, researchers say. The symptoms of what the researchers have dubbed "dopamine agonist withdrawal syndrome" have been linked to a disruption in levels of dopamine in the brain, according to the study published in the Jan. 12 issue of the Archives of Neurology. "Like cocaine and methamphetamines, dopamine agonists work by stimulating the reward pathways in the brain," senior study author Dr. Melissa J. Nirenberg, said in a news release from Weill Cornell Medical Center. "For this reason, it makes sense that they would engender similar withdrawal symptoms, particularly in those with high cumulative drug exposure," explained Nirenberg, associate ... Read more

Related support groups: Parkinson's Disease, Mirapex, Requip, Sinemet, Ropinirole, Emsam, Azilect, Pramipexole, Levodopa, Carbidopa, Bromocriptine, Selegiline, Amantadine, Parlodel, Neupro, Stalevo, Sinemet CR, Carbidopa/Levodopa, Requip XL, Comtan

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Restless Legs Syndrome, Periodic Limb Movement Disorder, Parkinson's Disease

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