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Renal Transplant News

Cancer History May Affect Survival After Organ Transplant

Posted 22 Apr 2016 by

FRIDAY, April 22, 2016 – Organ transplant patients who previously had cancer may be at increased risk for new cancer and early death compared to organ recipients with no cancer history, new research suggests. The findings indicate that transplant patients with a history of cancer may need closer monitoring to detect recurrent and new cancers early, the study's senior author, Dr. Nancy Baxter, said in a news release from St. Michael's Hospital in Toronto. Baxter is chief of the hospital's General Surgery Department. She and her colleagues reviewed 33 studies that included a total of nearly 400,000 patients in 12 countries. They found that organ recipients with previous cancer were 1.5 times more likely to die prematurely from any cause than those with no previous cancer. Moreover, those with previous cancer were nearly twice as likely to develop a new cancer and had three times higher ... Read more

Related support groups: Surgery, Cancer, Renal Transplant, Organ Transplant - Rejection Prophylaxis, Graft-versus-host disease, Kidney Transplant, Rejection Reversal

Online Tool Helps Predict Chances of Kidney Failure, Study Finds

Posted 12 Jan 2016 by

TUESDAY, Jan. 12, 2016 – A new online tool may help predict whether someone with chronic kidney disease will develop kidney failure in the next two to five years. Using results from kidney function tests, the tool helps those at high risk for kidney failure prepare for dialysis or kidney transplant. It also provides reassurance to those who likely won't progress to kidney failure, said lead researcher Dr. Navdeep Tangri, an associate professor of nephrology at the University of Manitoba in Winnipeg, Canada. "This study sets the stage for the tool to be used globally for all patients with kidney disease. The tool helps patients plan their lives by knowing what their risk is for dialysis," Tangri said. To find out the risk of kidney failure, patients need blood and urine test results from their doctor to enter into the online calculator, along with their age and sex, Tangri explained. ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Peritoneal dialysis, Diagnosis and Investigation

Kidney Donors, Recipients Want to Know More About Each Other

Posted 18 Aug 2015 by

TUESDAY, Aug. 18, 2015 – Most living kidney donors and recipients would like to know more about each other's health before a transplant, a new study indicates. Currently, a transplant candidate must be told if the donor is at increased risk for hepatitis or HIV, but rules are unclear about what other health information can be shared. "Our finding that both donors and recipients support greater sharing of health and health-behavior information challenges the current approach to disclosure in organ transplantation," said study author Dr. Lainie Friedman Ross, of the University of Chicago. Researchers surveyed 76 kidney transplant recipients or candidates and 160 potential or actual donors. They found that 88 percent of the respondents said recipients should receive donors' general health information, and nearly four out of five said donors should be given recipients' general health ... Read more

Related support groups: Renal Failure, Renal Transplant, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Hyperphosphatemia of Renal Failure

Too Few Kidney Dialysis Patients Referred for Organ Transplant, Study Finds

Posted 11 Aug 2015 by

TUESDAY, Aug. 11, 2015 – Although a kidney transplant is considered the best hope for people struggling with end-stage renal disease, a new study conducted in Georgia found three-quarters of these patients weren't even evaluated for a possible transplant within their first year of dialysis. That finding flies in the face of U.S. regulations that require all dialysis centers to fully inform these patients about all available treatment options. Those options include kidney transplantation, a typically less expensive intervention than ongoing dialysis and one that also promises greater longevity and a better quality of life, the researchers noted. What's more, the team found a huge variation in statewide referral rates. Some dialysis centers failed to send even a single first-year patient for a transplant consultation, while others referred 75 percent of their new patients. It remains ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Diabetic Kidney Disease, Peritoneal dialysis, Diabetic Nephropathy, Organ Transplant, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure, Hypertensive Renal Disease, Anuria, Renal and Genitourinary Disorders

Cooling Bodies of Brain-Dead Donors May Boost Kidney Function After Transplant

Posted 29 Jul 2015 by

WEDNESDAY, July 29, 2015 – Transplant surgeons may have found a simple way to improve the functioning of kidneys from brain-dead donors: Cool the donor's body by just a few degrees. Experts said the advance, reported in the July 30 issue of the New England Journal of Medicine, could free up more donor kidneys for the many people now on transplant waitlists. "This is a simple, zero-cost intervention that can be done in any country in the world," said lead researcher Dr. Claus Niemann, a professor of anesthesia and surgery at the University of California, San Francisco. "We think this will liberate more organs, and get more people off of waitlists," Niemann said. Kidney transplants can come from a living or deceased donor, but, for various reasons, those from living donors have a better shot at success. They are less likely to be rejected, and typically last longer: About 80 percent of ... Read more

Related support groups: Renal Failure, Renal Transplant, Chronic Kidney Disease, Peritoneal dialysis, Organ Transplant

HIV Patients May Fare as Well as Others With Kidney Transplants

Posted 19 Mar 2015 by

THURSDAY, March 19, 2015 – Kidney transplant patients with HIV have similar survival rates as those without HIV, a new study finds. The study included 510 HIV-positive adults who had kidney transplants in the United States between 2002 and 2011. Overall, these patients had similar five- and 10-year survival rates as kidney transplant patients without HIV. However, transplant recipients who had both HIV and hepatitis C had lower survival rates than those without HIV: 69 percent versus 75 percent after five years, and 50 percent versus 54 percent after 10 years, the study found. About 25 percent of kidney transplant patients with HIV also have hepatitis C, according to the study published March 19 in the Journal of the American Society of Nephrology. The findings suggest that excellent results are possible among HIV-positive kidney transplant recipients. However, doctors should be ... Read more

Related support groups: HIV Infection, Renal Transplant

Frailty Tied to Lower Survival Rates After Kidney Transplant

Posted 30 Oct 2014 by

THURSDAY, Oct. 30, 2014 – Physical frailty may lead to worse five-year survival rates among kidney transplant patients, regardless of their age, a new study shows. The findings suggest that patients should be screened for frailty before kidney transplantation, and that those identified as frail need to be closely monitored after their transplant, the study authors said. The researchers assessed frailty in 537 patients around the time of their kidney transplant. Five years later, survival rates were 91.5 percent for non-frail patients, 86 percent for intermediately frail patients, and 77.5 percent for frail patients, according to the study published online Oct. 30 in the American Journal of Transplantation. "Our results suggest that frail kidney transplant recipients are at twice the risk of mortality even after accounting for important recipient, transplant and donor characteristics," ... Read more

Related support groups: Renal Transplant

Kidney Transplant Beats Intensive Dialysis, Study Says

Posted 25 May 2014 by

THURSDAY, May 22, 2014 – Despite short-term risks, kidney transplant patients are less likely to die prematurely than kidney failure patients receiving the most advanced dialysis treatments, new research suggests. Canadian scientists found that patients receiving donor kidneys – depending on the quality of the organ match – were up to 61 percent less likely to experience treatment failure or death over an 11-year study period than those undergoing at least 16 hours of in-home dialysis each week. Patients receiving donor kidneys, however, had higher risks of being hospitalized within the first year after the transplant. "This gives us more positive evidence to continue to promote transplantation to patients on intensive dialysis because of the better outcomes, acknowledging that some aren't eligible for transplant," said study author Dr. Karthik Tennankore, an assistant professor of ... Read more

Related support groups: Renal Transplant

Diabetics Fare Well After Kidney Transplants, Study Finds

Posted 9 May 2014 by

FRIDAY, May 9, 2014 – Survival rates for people with diabetes who have a kidney transplant are similar to those of people without diabetes, a new study finds. Researchers looked at nearly 1,700 people who received new kidneys between 1996 and 2007, including about 400 with diabetes. Before 2004, kidney transplant patients with diabetes were more than twice as likely to die within five years as those without diabetes. But after 2004, the five-year survival rate for people with diabetes was similar to that of people without diabetes, according to the study published online recently in the journal Kidney International. The findings show that there have been major improvements in the management of kidney transplant patients with diabetes, the Mayo Clinic researchers said. Specifically, the improvements in patient care led to significant declines in heart problems and infections. "We were ... Read more

Related support groups: Renal Transplant

Outcomes Improving for Kids With Kidney Transplants

Posted 10 Mar 2014 by

MONDAY, March 10, 2014 – U.S. children in need of a kidney transplant are faring better now than a couple of decades ago, but there is still plenty of room for improvement, a new study finds. Kidney failure is relatively uncommon in children – affecting five to 10 kids per million each year, according to study background information. But when it happens, the optimal treatment is a kidney transplant, which about 800 U.S. children undergo each year. And the outlook for those kids has been steadily improving over the past 25 years, finds the new study published online March 10 and in the April print issue of Pediatrics. Researchers found that among U.S. children who received a donor kidney in 2001, just over 90 percent were still alive 10 years later. That compared with a 10-year survival rate of 78 percent among kids who had a transplant in 1987. The donor kidneys, themselves, were ... Read more

Related support groups: Renal Transplant

Kidney Donation a Low-Risk Choice, Study Finds

Posted 11 Feb 2014 by

TUESDAY, Feb. 11, 2014 – People who donate a kidney have an extremely low risk of developing kidney failure in their remaining organ, according to a new study. The risk among living kidney donors is even lower than for people with two kidneys, the Johns Hopkins researchers said. They added that the findings should reassure people who are considering donating a kidney. The investigators looked at data from more than 96,000 adults in the United States who donated a kidney between April 1994 and November 2011 and were followed for up to 15 years. They were compared to more than 20,000 people with two kidneys. The kidney failure rate was 90 per 10,000 among the donors and 326 per 10,000 among people in the general population, according to the study published in the Feb. 12 issue of the Journal of the American Medical Association. The risk of kidney failure among donors varied by race, with ... Read more

Related support groups: Renal Transplant

Risks for Kidney Donors Decline, Study Finds

Posted 27 Sep 2013 by

THURSDAY, Sept. 26 – Kidney donors' risk of complications and the length of their hospital stays have decreased in recent years, a new study finds. Live donors provide the organs in more than one-third of kidney transplants performed in the United States. Previous research has suggested that live donors face minimal health risks, but there have been few comprehensive studies. In order to determine trends regarding complications and other health issues experienced by live donors, the authors of the new study analyzed data from more than 69,000 donors between 1998 and 2010. They represented 89 percent of U.S. donors during that period. The researchers found that complications among live donors fell from slightly more than 10 percent in 1998 to less than 8 percent in 2010, and hospital stays after donating a kidney decreased from almost four days to less than three days. The rates of ... Read more

Related support groups: Renal Transplant

Almost Half of Americans Would Consider Donating Kidney to Stranger: Poll

Posted 25 Apr 2013 by

THURSDAY, April 25 – Nearly half of Americans now say they would consider donating a kidney to a stranger, a new survey finds. The number was even higher – 84 percent – when the Mayo Clinic's national poll asked respondents whether they would be very or somewhat likely to consider donating a kidney or portion of their liver to a close friend or family member. The results reveal an uptick in people's willingness to consider donating an organ. A 2001 Gallup survey found that 76 percent of respondents would likely donate a kidney to a close friend, while 24 percent said they would give a kidney to a stranger. The new findings are encouraging, said Dr. Mikel Prieto, surgical director of kidney transplantation at the Mayo Clinic in Rochester, Minn. "As living organ donation becomes more widely known and accepted – and as the safety and surgical proficiency continue to improve – we hope ... Read more

Related support groups: Renal Transplant

More U.S. Kidney Exchanges Would Allow 1,000 Additional Transplants Yearly

Posted 14 Mar 2013 by

THURSDAY, March 14 – An extra 1,000 patients in the United States could receive kidney transplants each year if hospitals performed more transplants using paired kidney exchanges, according to a new study. These exchanges, also called kidney chains, allow incompatible donors to give a kidney on a loved one's behalf, and in return the loved one gets a compatible kidney from another person – usually a stranger. The first such exchange took place in 1999 and the numbers have increased from 93 in 2006 to 553 in 2010. However, this growth has stalled, mainly due to financial issues related to logistics, administrative costs and insurance coverage for donors, Johns Hopkins researchers said. "There are more than 100,000 people waiting for a kidney transplant in the United States," study leader Dr. Dorry Segev, an associate professor of surgery and epidemiology at the Johns Hopkins University ... Read more

Related support groups: Renal Transplant

Blacks Less Likely to Receive Kidney Transplant Early On, Study Finds

Posted 31 Jan 2013 by

THURSDAY, Jan. 31 – Black people and those without private health insurance are less likely than others to receive a kidney transplant before their condition deteriorates to the point that they need dialysis, according to researchers from Johns Hopkins University School of Medicine, in Baltimore. This racial health disparity shows that more needs to be done to ensure the equitable timing of transplants, the researchers said. They added that the longer patients remain on dialysis, the worse they do after receiving a donor kidney. "We found that, while some regions performed ... transplants more than others, region was not a big factor in determining preemptive transplant rates," Dr. Morgan Grams said in a university news release. "Rather, we were struck by the disparities by race and insurance type: African-Americans were much less likely to receive kidney transplantation prior to ... Read more

Related support groups: Renal Transplant

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