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Related terms: Kidney Transplant

Frailty Tied to Lower Survival Rates After Kidney Transplant

Posted 30 Oct 2014 by Drugs.com

THURSDAY, Oct. 30, 2014 – Physical frailty may lead to worse five-year survival rates among kidney transplant patients, regardless of their age, a new study shows. The findings suggest that patients should be screened for frailty before kidney transplantation, and that those identified as frail need to be closely monitored after their transplant, the study authors said. The researchers assessed frailty in 537 patients around the time of their kidney transplant. Five years later, survival rates were 91.5 percent for non-frail patients, 86 percent for intermediately frail patients, and 77.5 percent for frail patients, according to the study published online Oct. 30 in the American Journal of Transplantation. "Our results suggest that frail kidney transplant recipients are at twice the risk of mortality even after accounting for important recipient, transplant and donor characteristics," ... Read more

Related support groups: Renal Transplant

Kidney Transplant Beats Intensive Dialysis, Study Says

Posted 25 May 2014 by Drugs.com

THURSDAY, May 22, 2014 – Despite short-term risks, kidney transplant patients are less likely to die prematurely than kidney failure patients receiving the most advanced dialysis treatments, new research suggests. Canadian scientists found that patients receiving donor kidneys – depending on the quality of the organ match – were up to 61 percent less likely to experience treatment failure or death over an 11-year study period than those undergoing at least 16 hours of in-home dialysis each week. Patients receiving donor kidneys, however, had higher risks of being hospitalized within the first year after the transplant. "This gives us more positive evidence to continue to promote transplantation to patients on intensive dialysis because of the better outcomes, acknowledging that some aren't eligible for transplant," said study author Dr. Karthik Tennankore, an assistant professor of ... Read more

Related support groups: Renal Transplant

Diabetics Fare Well After Kidney Transplants, Study Finds

Posted 9 May 2014 by Drugs.com

FRIDAY, May 9, 2014 – Survival rates for people with diabetes who have a kidney transplant are similar to those of people without diabetes, a new study finds. Researchers looked at nearly 1,700 people who received new kidneys between 1996 and 2007, including about 400 with diabetes. Before 2004, kidney transplant patients with diabetes were more than twice as likely to die within five years as those without diabetes. But after 2004, the five-year survival rate for people with diabetes was similar to that of people without diabetes, according to the study published online recently in the journal Kidney International. The findings show that there have been major improvements in the management of kidney transplant patients with diabetes, the Mayo Clinic researchers said. Specifically, the improvements in patient care led to significant declines in heart problems and infections. "We were ... Read more

Related support groups: Renal Transplant

Outcomes Improving for Kids With Kidney Transplants

Posted 10 Mar 2014 by Drugs.com

MONDAY, March 10, 2014 – U.S. children in need of a kidney transplant are faring better now than a couple of decades ago, but there is still plenty of room for improvement, a new study finds. Kidney failure is relatively uncommon in children – affecting five to 10 kids per million each year, according to study background information. But when it happens, the optimal treatment is a kidney transplant, which about 800 U.S. children undergo each year. And the outlook for those kids has been steadily improving over the past 25 years, finds the new study published online March 10 and in the April print issue of Pediatrics. Researchers found that among U.S. children who received a donor kidney in 2001, just over 90 percent were still alive 10 years later. That compared with a 10-year survival rate of 78 percent among kids who had a transplant in 1987. The donor kidneys, themselves, were ... Read more

Related support groups: Renal Transplant

Kidney Donation a Low-Risk Choice, Study Finds

Posted 11 Feb 2014 by Drugs.com

TUESDAY, Feb. 11, 2014 – People who donate a kidney have an extremely low risk of developing kidney failure in their remaining organ, according to a new study. The risk among living kidney donors is even lower than for people with two kidneys, the Johns Hopkins researchers said. They added that the findings should reassure people who are considering donating a kidney. The investigators looked at data from more than 96,000 adults in the United States who donated a kidney between April 1994 and November 2011 and were followed for up to 15 years. They were compared to more than 20,000 people with two kidneys. The kidney failure rate was 90 per 10,000 among the donors and 326 per 10,000 among people in the general population, according to the study published in the Feb. 12 issue of the Journal of the American Medical Association. The risk of kidney failure among donors varied by race, with ... Read more

Related support groups: Renal Transplant

Risks for Kidney Donors Decline, Study Finds

Posted 27 Sep 2013 by Drugs.com

THURSDAY, Sept. 26 – Kidney donors' risk of complications and the length of their hospital stays have decreased in recent years, a new study finds. Live donors provide the organs in more than one-third of kidney transplants performed in the United States. Previous research has suggested that live donors face minimal health risks, but there have been few comprehensive studies. In order to determine trends regarding complications and other health issues experienced by live donors, the authors of the new study analyzed data from more than 69,000 donors between 1998 and 2010. They represented 89 percent of U.S. donors during that period. The researchers found that complications among live donors fell from slightly more than 10 percent in 1998 to less than 8 percent in 2010, and hospital stays after donating a kidney decreased from almost four days to less than three days. The rates of ... Read more

Related support groups: Renal Transplant

Almost Half of Americans Would Consider Donating Kidney to Stranger: Poll

Posted 25 Apr 2013 by Drugs.com

THURSDAY, April 25 – Nearly half of Americans now say they would consider donating a kidney to a stranger, a new survey finds. The number was even higher – 84 percent – when the Mayo Clinic's national poll asked respondents whether they would be very or somewhat likely to consider donating a kidney or portion of their liver to a close friend or family member. The results reveal an uptick in people's willingness to consider donating an organ. A 2001 Gallup survey found that 76 percent of respondents would likely donate a kidney to a close friend, while 24 percent said they would give a kidney to a stranger. The new findings are encouraging, said Dr. Mikel Prieto, surgical director of kidney transplantation at the Mayo Clinic in Rochester, Minn. "As living organ donation becomes more widely known and accepted – and as the safety and surgical proficiency continue to improve – we hope ... Read more

Related support groups: Renal Transplant

More U.S. Kidney Exchanges Would Allow 1,000 Additional Transplants Yearly

Posted 14 Mar 2013 by Drugs.com

THURSDAY, March 14 – An extra 1,000 patients in the United States could receive kidney transplants each year if hospitals performed more transplants using paired kidney exchanges, according to a new study. These exchanges, also called kidney chains, allow incompatible donors to give a kidney on a loved one's behalf, and in return the loved one gets a compatible kidney from another person – usually a stranger. The first such exchange took place in 1999 and the numbers have increased from 93 in 2006 to 553 in 2010. However, this growth has stalled, mainly due to financial issues related to logistics, administrative costs and insurance coverage for donors, Johns Hopkins researchers said. "There are more than 100,000 people waiting for a kidney transplant in the United States," study leader Dr. Dorry Segev, an associate professor of surgery and epidemiology at the Johns Hopkins University ... Read more

Related support groups: Renal Transplant

Blacks Less Likely to Receive Kidney Transplant Early On, Study Finds

Posted 31 Jan 2013 by Drugs.com

THURSDAY, Jan. 31 – Black people and those without private health insurance are less likely than others to receive a kidney transplant before their condition deteriorates to the point that they need dialysis, according to researchers from Johns Hopkins University School of Medicine, in Baltimore. This racial health disparity shows that more needs to be done to ensure the equitable timing of transplants, the researchers said. They added that the longer patients remain on dialysis, the worse they do after receiving a donor kidney. "We found that, while some regions performed ... transplants more than others, region was not a big factor in determining preemptive transplant rates," Dr. Morgan Grams said in a university news release. "Rather, we were struck by the disparities by race and insurance type: African-Americans were much less likely to receive kidney transplantation prior to ... Read more

Related support groups: Renal Transplant

Obese Patients Urged to Lose Weight Before Kidney Transplant

Posted 21 Jan 2013 by Drugs.com

MONDAY, Jan. 21 – Obese people who receive kidney transplants appear to be at increased risk for problems such as wound infections, transplant failure and heart disease during their recovery, researchers have found. Obese kidney transplant patients also have higher health care costs than non-obese patients, the Saint Louis University researchers said. The new findings are based on an examination of data from multiple studies and were released online in advance of publication in an upcoming print issue of the American Journal of Nephrology. "Lifestyle alterations that seem reasonable to improve health outcomes should be encouraged," study co-leader Dr. Betsy Tuttle-Newhall, director of abdominal transplant, said in a university news release. "Just as we require patients with alcoholic liver disease to stop drinking prior to transplant, it is reasonable to ask kidney transplant ... Read more

Related support groups: Obesity, Renal Transplant

Donor Kidney Re-Used in Second Patient After Failing in First

Posted 25 Apr 2012 by Drugs.com

WEDNESDAY, April 25 – In a groundbreaking medical report, U.S. doctors describe a case where a kidney transplanted into one patient had to be removed but was then successfully transplanted into another patient. The team at Northwestern University in Chicago said that Ray Fearing, 27, received a kidney from his sister after he developed kidney failure due to a disease called focal segmental glomerulosclerosis (FSGS). The disease causes scar tissue to develop on the part of the kidney that filters waste out of blood. However, just days after receiving the new kidney Fearing showed signs of a disease recurrence and doctors told him they had to remove the new organ. The doctors also told Fearing they could potentially save another person's life by re-transplanting the organ – something that had never succeeded before with a kidney. "In over 50 percent of cases, transplant does not stop ... Read more

Related support groups: Renal Transplant

Stem Cell Therapy Could Boost Kidney Transplant Success: Study

Posted 20 Mar 2012 by Drugs.com

TUESDAY, March 20 – A novel technique that uses a kidney transplant recipient's own stem cells may someday replace or reduce the initial use of anti-rejection medications, new research suggests. Six months after receiving a kidney transplant, only about 8 percent of people given their own mesenchymal stem cells experienced rejection compared with almost 22 percent of people on the standard anti-rejection drugs, according to the study. "Mesenchymal stem cells are stem cells that can be differentiated into a variety of cells," explained Dr. Camillo Ricordi, study senior author and director of the Cell Transplant Center and Diabetes Research Institute at the University of Miami Miller School of Medicine. "If you infuse mesenchymal stem cells at the time of the transplant, you could replace the use of powerful anti-rejection drugs, and maybe replace immunosuppressants altogether," he said. ... Read more

Related support groups: Renal Transplant

Black Children Less Likely to Get Kidney Transplant Before Dialysis

Posted 10 Nov 2011 by Drugs.com

THURSDAY, Nov. 10 – Minority children are less likely than white children to get a kidney transplant before their kidney disease gets so bad they need dialysis, U.S. researchers find. They also found that black children with kidney failure and no health insurance are more likely than whites to die while waiting for a kidney transplant. The Emory University researchers analyzed 2000-08 data from the U.S. Renal Data System, and found that white children had a 56 percent higher average annual rate of preemptive transplants than blacks and a 50 percent higher rate than Hispanics. A preemptive transplant is one performed before a patient begins dialysis. White children were also more likely to have a living donor. Nearly 79 percent of whites had living donor, compared to 57 percent of Hispanic children and 49 percent of black children. The reasons for these racial disparities aren't clear, ... Read more

Related support groups: Renal Transplant

Kidney Donation Doesn't Put Older Adults at Risk

Posted 3 Nov 2011 by Drugs.com

THURSDAY, Nov. 3 – People older than 70 can donate a kidney without risking their lives but their donated kidneys don't last as long as those from younger living donors, a new study shows. However, kidneys from living elderly donors last just as long as kidneys from deceased donors, the researchers said. The findings are important in light of the serious shortage of donor kidneys in the United States. Nearly 90,000 people are waiting for a kidney transplant and many of them will die before a suitable kidney becomes available, according to background information in a journal news release. In this study, researchers compared 219 healthy adults older than 70 who donated a kidney with healthy adults in the same age group who did not donate an organ. Those who donated a kidney were no more likely than non-donors to die within one, five or 10 years. Instead, organ donors had a lower death ... Read more

Related support groups: Renal Transplant

Densensitization Procedure Helps Hard-to-Match Kidney Recipients

Posted 27 Jul 2011 by Drugs.com

WEDNESDAY, July 27 – A combination therapy that "desensitizes" kidney transplant recipients could help hard-to-match patients find a needed kidney faster. The desensitization procedure combines the use of plasmapheresis – a machine that filters the blood plasma to remove antibodies – and low-doses of a medication called intravenous immune globulin (IVIG). The combination of these therapies improves survival rates dramatically. Eight years after receiving a transplant, survival rates were 81 percent for those who received the treatment compared to just 31 percent for people who had to stay on dialysis, new research found. "This is a huge unmet problem. There are probably as many as 30,000 people who have been exposed to foreign tissue waiting for a kidney. They're really hard to match," explained study author Dr. Robert Montgomery, director of the comprehensive transplant program at ... Read more

Related support groups: Renal Transplant, Gammagard, Gamunex, Sandoglobulin, Flebogamma, Immune Globulin Intravenous, Octagam, Privigen, Carimune, Carimune NF, Polygam S/D, Venoglobulin-S 5%, Gamimune N 10%, Panglobulin NF, Gammar-P IV, Venoglobulin-S 10%, Iveegam En, Gamimune, Panglobulin, Gammaplex

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