Join the 'Pulmonary Hypertension' group to help and get support from people like you. How it works

Pulmonary Hypertension Blog

Related terms: PAH

Viagra May Help Children With Rare Blood Pressure Disorder

Posted 25 Oct 2011 by Drugs.com

TUESDAY, Oct. 25 – New research suggests that the active ingredient in the erectile dysfunction drug Viagra, which was initially developed as a treatment for heart disease, could help children with a rare condition called pulmonary arterial hypertension. The drug, which is expensive to take regularly and has side effects, is already approved to treat the condition in adults. And some pediatricians use it to treat children, said Dr. Thomas Kulik, senior associate in cardiology at Children's Hospital Boston. But it has not yet received U.S. Food and Drug Administration approval for that purpose. Pulmonary arterial hypertension, a rare condition, causes abnormally high blood pressure in the arteries that lead to the lungs. It can be inherited, accompany some forms of heart disease or occur for no known reason, Kulik said. The disease can limit the ability to exercise and lead to heart ... Read more

Related support groups: Viagra, Cialis, Pulmonary Hypertension, Tadalafil, Sildenafil, Revatio, Adcirca

New Uses Found for Old Drugs

Posted 17 Aug 2011 by Drugs.com

WEDNESDAY, Aug. 17 – Many drugs already approved to combat certain illnesses may also be helpful in treating a slew of other seemingly unrelated health problems, a new study indicates. Researchers from the Stanford University School of Medicine used computers to pair drugs with all illnesses for which they might be beneficial. They argued their findings make the case for drug repositioning – or the use of existing drugs to boost progress on the development of new treatments – for other serious conditions. One high-profile example of how a drug can be used to treat conditions for which it was not originally intended involves Viagra. This medication was first developed to treat heart problems. It turned out that Viagra is also effective in treating erectile dysfunction as well as a lung disorder called pulmonary hypertension. The researchers from Stanford, however, sought to predict ... Read more

Related support groups: Viagra, Topamax, Crohn's Disease, Topiramate, Lung Cancer, Pulmonary Hypertension, Revatio, Sildenafil, Tagamet, Topamax Sprinkle, Cimetidine, Tagamet HB, Topiragen

Standard Heart Drugs Won't Ease Pulmonary Hypertension

Posted 18 May 2011 by Drugs.com

WEDNESDAY, May 18 – Although commonly used to treat heart disease, aspirin and simvastatin offer no benefit to patients suffering from pulmonary arterial hypertension, or PAH, a progressive disease characterized by increased blood pressure in the arteries of the lungs, according to new research. In a study funded by the U.S. National Institutes of Health, researchers divided 65 patients into four groups: one receiving aspirin; one taking simvastatin; one receiving both drugs; and one in which patients received a placebo (or dummy pill). "Surprisingly, we found no evidence that aspirin or simvastatin had beneficial clinical effects in this population," said Dr. Steven Kawut, study lead author and associate professor of medicine and epidemiology at the University of Pennsylvania School of Medicine. After taking the assigned medication for six months, patients were asked to see how far ... Read more

Related support groups: Aspirin, Simvastatin, Zocor, Pulmonary Hypertension, Ecotrin, Bayer Aspirin, Bufferin, Buffered Aspirin, Easprin, ZORprin, St Joseph Aspirin, Aspergum, Litecoat Aspirin, Tri-Buffered Aspirin, Aspiritab

FDA Approves Intravenous Formulation Of Pfizer's Revatio (Sildenafil) For The Treatment Of Pulmonary Arterial Hypertension

Posted 2 Dec 2009 by Drugs.com

Revatio is the Only Treatment in Its Class with Both Oral and Intravenous Formulations NEW YORK--(BUSINESS WIRE)--Nov 20, 2009 - Pfizer announced today that the U.S. Food and Drug Administration (FDA) has approved Revatio (sildenafil) Injection, an intravenous formulation of Revatio. Revatio is the only FDA-approved phosphodiesterase-5 (PDE5) inhibitor available in both tablet and intravenous formulations. Revatio is indicated for the treatment of adult patients with pulmonary arterial hypertension (WHO Group I) to improve exercise ability and delay clinical worsening. The delay in clinical worsening was demonstrated when Revatio was added to background epoprostenol therapy. The efficacy of Revatio has not been adequately evaluated in patients taking bosentan concurrently. Revatio Injection is for the continued treatment of patients with pulmonary arterial hypertension who are currently ... Read more

Related support groups: Pulmonary Hypertension, Revatio, Sildenafil

Adcirca Approved for Lung Disorder

Posted 26 May 2009 by Drugs.com

TUESDAY, May 26 – United Therapeutics has received approval from the U.S. Food and Drug Administration to market Adcirca (tadalafil) to treat pulmonary arterial hypertension (PAH), a high blood pressure disorder affecting the arteries that carry oxygen from the heart to the lungs. Tadalafil is the active ingredient in the erectile dysfunction drug Cialis. In a news release, United Therapeutics said it was licensing the drug from Cialis' maker, Eli Lilly. United Therapeutics said Adcirca would be available in August. The drug should not be used in people who take nitrates, commonly prescribed for chest pain. The combination could cause a sudden, dangerous drop in blood pressure, the company said. PAH – which has no cure – has typical symptoms including shortness of breath, fatigue, chest pain and racing heartbeat, according to the U.S. National Institutes of Health. The most common ... Read more

Related support groups: Pulmonary Hypertension

Cialis May Help Ease Pulmonary Hypertension

Posted 28 Oct 2008 by Drugs.com

WEDNESDAY, Oct. 29 – Cialis (tadalafil), a drug used to treat erectile dysfunction, appears effective in treating pulmonary hypertension, researchers report. Pulmonary hypertension is caused by high blood pressure in the arteries that supply the lungs with blood. People who suffer from the condition can become tired, dizzy and short of breath, because the arteries feeding the lungs constrict and reduce the supply of oxygenated blood being circulating throughout the body. But Cialis "was found to improve exercise capacity, health-related quality of life, delay time to clinical worsening, and improve hemodynamic [blood-linked] parameters of disease severity," said lead researcher Dr. Robyn J. Barst, a professor of pediatrics at Columbia University College of Physicians & Surgeons in New York City. The drug was also well-tolerated, she added. The report was to be presented Tuesday at the ... Read more

Related support groups: Cialis, Pulmonary Hypertension

Ask a Question

Further Information

Related Condition Support Groups

Pulmonary Heart or Vascular Disease

Related Drug Support Groups

tadalafil, Revatio, sildenafil, Tracleer, isosorbide dinitrate, bosentan, Remodulin, Adcirca, Flolan, view more... Ventavis, Sorbitrate, treprostinil, Letairis, Isochron, Tyvaso, IsoDitrate, Veletri, Isordil Tembids, Dilatrate-SR, iloprost, epoprostenol, Isordil Titradose, ambrisentan, Isordil, ISDN