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Steroid Injections Probably Won't Help Your Lower Back Pain

Posted 11 days ago by Drugs.com

MONDAY, Aug. 24, 2015 – Steroid injections for lower back pain may provide some relief for certain patients, but any benefits are temporary, a new study finds. Lower back pain related to herniated disk (when intervertebral disks become compressed and bulge) and, to a lesser degree, spinal stenosis (narrowing of the spinal canal), is often treated with epidural steroid injections, the researchers said. But after reviewing 38 previously published studies, the researchers found no strong evidence to support their use for these conditions. "These injections may not be as effective as perceived, and decisions should be based on an informed discussion of risks, benefits, and potential options, including surgery, medications and nonpharmacological options like exercise therapy," said lead researcher Dr. Roger Chou, a professor of medicine at the Oregon Health & Science University. Chou said ... Read more

Related support groups: Back Pain, Prednisone, Sciatica, Methylprednisolone, Prednisolone, Herniated Disc, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Scoliosis, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC

Steroids May Help Speed Pneumonia Recovery, Study Finds

Posted 10 Aug 2015 by Drugs.com

MONDAY, Aug. 10, 2015 – Steroid treatment may hasten pneumonia patients' recovery and cut their risk of complications, a new review suggests. The findings "should lead to an important change in treatment for pneumonia," lead author Dr. Reed Siemieniuk, a physician and graduate student at McMaster University in Hamilton, Canada, said in a university news release. "Corticosteroids are inexpensive and readily available around the world. Millions of patients will benefit from this new evidence," he said. But one expert said a bit more research may be needed first. "With such modest – though measurable – effects of treatment, a large multi-center randomized clinical trial," would still be necessary to confirm the new findings and "perhaps justify a change in the standard of care," said Dr. Bruce Polsky. He is chair of the department of medicine at Winthrop-University Hospital in Mineola, ... Read more

Related support groups: Prednisone, Methylprednisolone, Pneumonia, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred

Losing Weight May Ease Asthma in Obese People

Posted 26 Jun 2015 by Drugs.com

FRIDAY, June 26, 2015 – Losing weight may help reduce asthma severity in obese adults, a new Canadian study finds. "We were pleased to see significant improvement in asthma symptoms, as well as quality of life for these individuals. This study further supports the need to manage [chronic disorders] to improve patient lives," said study author Dr. Smita Pakhale, from The Ottawa Hospital and the University of Ottawa. People who are obese are about 1.5 times more likely to have asthma than those who aren't obese. A 3-unit increase in body mass index – BMI, an estimate of body fat based on weight and height – is associated with a 35 percent increase in the risk of asthma, the researchers said in a news release from the American College of Chest Physicians. A BMI of 18.5 to 24.9 is considered normal weight. A BMI of 25 to 29.9 is overweight, while 30 and over is considered obese. The ... Read more

Related support groups: Obesity, Asthma, Weight Loss, Asthma - Maintenance, Fluticasone, Asthma - Acute, Qvar, Flovent, Budesonide, Entocort, Mometasone, Bronchial, Entocort EC, Beclomethasone, Pulmicort Flexhaler, Alvesco, Asmanex Twisthaler, Allergic Asthma, Uceris, Pulmicort Turbuhaler

Steroids No Better for Sciatica Pain Than Placebo, Study Finds

Posted 19 May 2015 by Drugs.com

TUESDAY, May 19, 2015 – Doctors often prescribe steroid pills to ease the discomfort of sciatica – back and leg pain usually caused by a herniated disk in the lower back. But a new study finds steroids are no more effective than a placebo pill for the pain and provide only modest improvement in function. Sciatica affects about one in 10 people in their lifetime, the researchers said. For this study, 269 people with sciatica were randomly assigned to take an oral steroid (prednisone) or a placebo (a dummy medication) for 15 days. The participants were followed for up to a year. "When we compared the prednisone to placebo, there was a modest improvement in function," said study researcher Dr. Harley Goldberg, director of spine care services at Kaiser Permanente San Jose Medical Center in California. People reported they could go about their daily activities somewhat better than before. ... Read more

Related support groups: Pain, Back Pain, Prednisone, Chronic Pain, Neuralgia, Sciatica, Breakthrough Pain, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Neuropathic Pain, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol

Environmental Concerns Led to Jump in Cost of Asthma Inhalers: Study

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – Federal action to protect the ozone layer has resulted in a dramatic increase in the cost of asthma inhalers in recent years, according to a new study. In 2008, the U.S. Food and Drug Administration banned asthma inhalers containing chlorofluorocarbons (CFCs), substances that contribute to the depletion of ozone in the upper atmosphere. Immediately following the ban, the mean cost of asthma inhalers rose from $13.60 per prescription in 2004 to $25 in 2009, said lead study author Dr. Anupam Jena, an assistant professor of health care policy and medicine at Harvard Medical School in Boston. "We're talking about – at its peak – a 100 percent increase, a doubling of out-of-pocket costs," Jena said. The cost of asthma inhalers decreased slightly in the following months, dropping to an average $21 by the end of 2010, Jena said. Their price has hovered around that ... Read more

Related support groups: Asthma, Asthma - Maintenance, Fluticasone, Asthma - Acute, Qvar, Ribavirin, Flovent, Budesonide, Tobramycin, Entocort, Mometasone, Entocort EC, Beclomethasone, Pulmicort Flexhaler, Alvesco, Asmanex Twisthaler, Allergic Asthma, Ribasphere, Copegus, Uceris

They Overcame Childhood Cancer, But Now Obesity?

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – Certain treatments may increase a childhood cancer survivor's risk of obesity later in life, a new study says. "The ability to identify patients at increased risk may guide selection of therapeutic protocols that will maximize treatment outcomes while simultaneously minimizing the risk of long-term complications among children diagnosed with cancer," said study co-leader Kirsten Ness, of St. Jude Children's Research Hospital in Memphis. The researchers looked at nearly 2,000 people who'd been diagnosed with childhood cancer at least 10 years earlier. They found that almost half who underwent cranial radiation were obese. This compared with just over 29 percent of those who did not receive that type of treatment. Cranial radiation is used to prevent or delay the spread of cancer to the brain. The risk of obesity among survivors treated with cranial radiation was ... Read more

Related support groups: Obesity, Cancer, Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol

Women Hospitalized for Asthma More Often Than Men

Posted 5 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – After seeking medical treatment in the emergency room for an asthma attack, women are much more likely than men to need hospitalization, researchers report. Scientists analyzed the likelihood that 2,000 patients treated in the ER for asthma would need to be admitted to the hospital. Although the men and women had similar risk factors for a flare-up of their condition, women were still 60 percent more likely to be hospitalized, according to the study, published May 5 in the Annals of Allergy, Asthma and Immunology. "It's long been known that after puberty, asthma is more common in women than men," Dr. James Sublett, president of the American College of Allergy, Asthma and Immunology, said in a journal news release. "Only 10 percent of the women in this study had been seen by an allergist in the last year," Sublett added. "Those who see an allergist and use ... Read more

Related support groups: Asthma, Asthma - Maintenance, Fluticasone, Asthma - Acute, Qvar, Flovent, Budesonide, Entocort, Mometasone, Bronchial, Entocort EC, Beclomethasone, Pulmicort Flexhaler, Alvesco, Asmanex Twisthaler, Allergic Asthma, Uceris, Pulmicort Turbuhaler, Cromolyn, Pulmicort Respules

Gene May Play Part in How Kids Respond to Asthma Meds: Study

Posted 22 Apr 2015 by Drugs.com

WEDNESDAY, April 22, 2015 – Researchers say they've identified a gene that affects whether children with asthma respond to corticosteroids. Corticosteroids are the most effective treatment for chronic asthma and acute asthma attacks, but some children don't respond well to the drugs. Researchers analyzed the genomes of 57 children with asthma, and found that the activity of a gene called VNN-1 affected whether they were good or poor responders to corticosteroid treatment. The study was published April 21 in The Journal of Allergy and Clinical Immunology. The gene "may serve as a clinically useful biomarker to identify a subset of difficult-to-treat asthmatic children, and targeting the VNN-1 pathway may be useful as a therapeutic strategy," senior study author Dr. Gurjit Khurana Hershey, director of the Asthma Research Center at Cincinnati Children's Hospital Medical Center, said in a ... Read more

Related support groups: Asthma, Asthma - Maintenance, Fluticasone, Qvar, Flovent, Budesonide, Entocort, Mometasone, Bronchial, Entocort EC, Beclomethasone, Pulmicort Flexhaler, Alvesco, Asmanex Twisthaler, Uceris, Pulmicort Turbuhaler, Pulmicort Respules, Aerobid, Flunisolide, Flovent HFA

FDA Panel Mulls Worth of Steroid Shots For Back Pain

Posted 25 Nov 2014 by Drugs.com

TUESDAY, Nov. 25, 2014 – An expert advisory panel of the U.S. Food and Drug Administration will decide Tuesday whether to recommend that doctors stop giving steroid injections for back pain. These shots are commonly used to treat back pain, but they are not approved for this use and whether the risks outweigh the benefits is a matter of debate. According to the FDA, serious but rare side effects with these shots can include death, spinal cord blockage, paralysis, blindness, stroke, seizures, nerve injury and brain swelling. And experts are divided on whether steroid shots actually ease back pain. A study published earlier this year in the New England Journal of Medicine found that people who have lower back pain caused by spinal stenosis – a common condition among those over the age of 60 in which the open space in the spinal canal narrows from inflammation – are unlikely to get ... Read more

Related support groups: Back Pain, Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred

Many Expectant Moms Don't Get Steroids That Protect Preterm Babies

Posted 13 Aug 2014 by Drugs.com

WEDNESDAY, Aug. 13, 2014 – Only half of eligible women in low- and middle-income countries at risk for preterm birth receive an inexpensive drug that seems to help prevent complications and deaths in premature infants, a new study shows. Researchers analyzed the use of prenatal corticosteroid injections in more than 300,000 births in 29 countries, and found that only 52 percent of women eligible to receive the simple and effective treatment actually get it. This is despite the fact that corticosteroids given before birth have been shown to significantly lower preterm infants' risk of death, breathing problems, bleeding in the brain, and long-term complications such as cerebral palsy and poor motor skills, the researchers said. Rates of steroids given before birth ranges from 16 percent to 20 percent of eligible women in Afghanistan, Democratic Republic of Congo, Nepal and Niger to 88 ... Read more

Related support groups: Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Premature Labor, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred

Skip the Steroids for Shoulder Pain?

Posted 6 Aug 2014 by Drugs.com

TUESDAY, Aug. 5, 2014 – For relief of shoulder pain, physical therapy and steroid shots provide similar results, a new study finds. Researchers compared the two nonsurgical approaches in a group of 100-plus adults suffering from shoulder pain caused by rotator cuff problems, tendinitis or bursitis. "Whether you had a steroid injection or physical therapy, the improvement in each group was the same," said lead researcher Daniel Rhon, from the Center for the Intrepid at Brooke Army Medical Center at Fort Sam Houston, Texas. "It was also a rather large improvement, about 50 percent, and this improvement was maintained for at least one year," he said. But the group that received injections used more health care services and had significantly more shoulder-related doctor visits during the year of the study, Rhon said. "Additional visits to your primary care provider may indicate that you ... Read more

Related support groups: Prednisone, Muscle Pain, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred

Steroid Shots May Not Help Back Pain

Posted 3 Jul 2014 by Drugs.com

WEDNESDAY, July 2, 2014 – People who have lower back pain caused by spinal stenosis – a condition that narrows the open space in the spinal canal – are unlikely to get relief from steroid shots, a new study finds. "Steroid injections are a common treatment for spinal stenosis, and we were surprised by the finding," said lead author Dr. Janna Friedly, an assistant professor of rehabilitation medicine at the University of Washington in Seattle. "These steroid injections aren't helpful," she said. "There is no added benefit to the steroid itself, so if people are considering these injections, I would recommend that they consider an alternative." Spinal stenosis causes pain by putting pressure on the spinal nerves. The condition is common in men and women over 60, according to the American Academy of Orthopaedic Surgeons. Spinal stenosis is often treated with injections of local ... Read more

Related support groups: Back Pain, Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred

Steroids May Not Be Wise Choice for Intensive-Care Patients

Posted 30 May 2014 by Drugs.com

FRIDAY, May 30, 2014 – Intensive-care unit patients who receive steroids seem to be at greater risk of developing delirium, according to a new study by Johns Hopkins researchers. Steroids are given to ICU patients for a number of reasons, including to reduce inflammation and to treat septic shock, the study authors said. The researchers examined the medical records of 330 lung injury patients who were on ventilators in intensive-care units of four Baltimore hospitals between 2004 and 2007. Patients were 52 percent more likely to develop delirium if they'd received steroids the previous day. Being older was also linked with an increased risk of delirium, which can cause poor memory and thinking, hallucinations, agitation and disorientation, the researchers said. The study authors noted that delirium typically subsides after a few days. But previous research has shown that delirium in ... Read more

Related support groups: Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred, Pulmicort Flexhaler

Study Finds Steroids May Not Be Helpful After Infant Liver Surgery

Posted 6 May 2014 by Drugs.com

SATURDAY, May 3, 2014 – High doses of steroids may not benefit infants who've had surgery for a serious liver disease, and the drugs may even cause harm, according to a new study. The findings offer new evidence in a controversy over whether steroid treatment in addition to surgery helps infants with a liver disease called biliary atresia. This condition is the leading reason for liver transplants in children, according to the study authors. "The results from this clinical trial differ from previous reports of a benefit from steroid therapy on bile drainage or survival in biliary atresia," co-lead investigator Dr. Jorge Bezerra, from Cincinnati Children's Hospital Medical Center, said in a news release from the hospital. "Although we cannot exclude some small potential benefit from steroid treatment, we observed no statistical differences in two-year survival between patients receiving ... Read more

Related support groups: Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred, Pulmicort Flexhaler

Preventive Steroids May Not Improve Heart Bypass Surgery Results

Posted 31 Mar 2014 by Drugs.com

MONDAY, March 31, 2014 – Although steroids are often given to patients undergoing heart bypass surgery, a large new study suggests this common practice has no benefit and could actually be harmful. Researchers found preventive steroids do not improve the outcome of these procedures and could put patients at greater risk for a heart attack after their surgery. The study authors said their findings challenge a practice doctors have used for decades. The study is scheduled for presentation Monday at the annual meeting of the American College of Cardiology (ACC), in Washington, D.C. Because the study was presented at a medical meeting, it should be viewed as preliminary until published in a peer-reviewed journal. "Based on these results, we suggest that steroids should not be used [as a preventive measure] during cardiac surgeries that require the use of cardiopulmonary bypass," lead ... Read more

Related support groups: Prednisone, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Medrol Dosepak, Depo-Medrol, Orapred, Pulmicort Flexhaler

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