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Psoriasis News

Related terms: Erythrodermic Psoriasis, Guttate Psoriasis, Inverse Psoriasis, Palmo-plantar Psoriasis, Psoriasis vulgaris, Pustular Psoriasis

Novartis Receives FDA Approval for Cosentyx (secukinumab) to Treat Patients with Ankylosing Spondylitis and Psoriatic Arthritis

Posted 17 Jan 2016 by Drugs.com

EAST HANOVER, N.J., Jan. 15, 2016 Novartis announced today that the US Food and Drug Administration (FDA) has approved Cosentyx (secukinumab) for two new indications - the treatment of adult patients with active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA). AS and PsA are both life-long, painful and debilitating inflammatory diseases that affect the joints and/or spine. If not treated effectively, both conditions can lead to irreversible joint and/or spinal bone damage caused by years of inflammation.2,3,4 With these new approvals, Cosentyx is now the first and only interleukin-17A (IL-17A) antagonist approved for AS, as well as moderate to severe plaque psoriasis and PsA, which impacts as many as 30% of patients with psoriasis.5 Cosentyx was approved for adult patients with moderate to severe plaque psoriasis in January 2015 and more than 13,000 patients with this ... Read more

Related support groups: Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Cosentyx, Secukinumab

New Drug for Severe Form of Arthritis Shows Promise in Trial

Posted 24 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 23, 2015 – A drug recently approved for the skin condition psoriasis may also help people with a debilitating form of arthritis that attacks the spine, a new clinical trial finds. The condition, called ankylosing spondylitis, causes inflammation around the vertebrae, which can lead to chronic pain and stiffness in the back and neck – and, in some people, eventually cause some vertebrae to fuse into an immobile position. In the new trial, researchers found that a drug called secukinumab (Cosentyx) helped control symptoms in 61 percent of spondylitis patients who were given the highest dose. Experts said the results, published Dec. 24 in the New England Journal of Medicine, could open up a new option for managing spondylitis. And new options are needed, said Dr. Scott Zashin, a fellow with the American College of Rheumatology who was not involved in the study. ... Read more

Related support groups: Psoriasis, Ankylosing Spondylitis, Plaque Psoriasis, Cosentyx, Psoriatic Arthropathy

'Designer Cells' Show Promise Against Psoriasis in Lab Mice

Posted 16 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 16, 2015 – Scientists say they've engineered cells capable of automatically detecting and treating psoriasis flare-ups in lab mice – in an early step toward a "precision" therapy for the chronic skin disease. Experts said they were "excited" by the findings, reported Dec. 16 in the journal Science Translational Medicine. But they also cautioned that a lot of work lies ahead. In the United States, more than 5 million people have psoriasis, according to the U.S. National Institutes of Health. The disease arises from an abnormal immune system response that triggers a rapid turnover of skin cells. As a result, people with psoriasis periodically develop thick, scaly patches on the skin that can be itchy or painful. When psoriasis is milder, skin treatments or UV light therapy can be enough to treat the symptoms. But people with more severe psoriasis often need pills or ... Read more

Related support groups: Psoriasis

LEO Pharma Announces U.S. Approval of Enstilar Foam (calcipotriene/betamethasone dipropionate) for Plaque Psoriasis

Posted 21 Oct 2015 by Drugs.com

Ballerup, Denmark 19 October, 2015: LEO Pharma announced today that the U.S. Food and Drug Administration (FDA) has approved Enstilar (calcipotriene/betamethasone dipropionate 50 micrograms/g / 0,5 mg/g) Foam for the treatment of psoriasis vulgaris in patients 18 years of age or older in the United States.1 Enstilar is a once-daily, alcohol-free topical treatment.1 “We are very pleased by the U.S. approval of Enstilar and believe it will provide patients with the type of treatment option that they are looking for,” said Gitte Aabo, President and CEO of LEO Pharma. “At LEO Pharma, we are committed to providing patients with innovative, new solutions and we believe the foam formulation of Enstilar can help patients living with psoriasis.” Enstilar was developed to treat patients with psoriasis vulgaris2,3 – the most common clinical form of psoriasis.4 The U.S. approval of Enstilar was ... Read more

Related support groups: Psoriasis, Plaque Psoriasis, Enstilar, Betamethasone/Calcipotriene

Psoriasis, Cold Sores Most Stigmatized Skin Disorders: Survey

Posted 9 Oct 2015 by Drugs.com

FRIDAY, Oct. 9, 2015 – Psoriasis and cold sores top the list of stigmatized skin conditions, a new survey indicates, but experts say much of the ill will directed at sufferers is misguided. Surveying 56 people, Boston researchers found that nearly 61 percent wrongly thought psoriasis – which produces widespread, scaly red skin lesions – looked contagious, and about nine in 10 said they would pity a person who had it. About four in 10 said herpes simplex, or cold sore, is the most bothersome skin condition. "We knew from other studies that psoriasis seemed to be more stigmatizing than other skin diseases, [and] we did this study to try to find out why," said study author Dr. Alexa Kimball, a dermatology professor at Harvard Medical School. "We suspected that the fact that it looked infectious could be part of the reason people reacted strongly to it, but we didn't expect that reaction ... Read more

Related support groups: Acne, Psoriasis, Eczema, Cold sores, Warts, Rosacea, Vitiligo, Plaque Psoriasis, Tinea Versicolor, Herpes Simplex Labialis, Minor Skin Conditions, Minor Skin Irritation

Worse Psoriasis, Less Healthy Arteries, Study Finds

Posted 8 Oct 2015 by Drugs.com

THURSDAY, Oct. 8, 2015 – The skin disorder psoriasis appears linked with artery inflammation, raising the odds for heart disease, a new study says. "As the amount of psoriasis increases, the amount of blood vessel inflammation increases," said senior investigator Dr. Nehal Mehta, a clinical investigator with the U.S. National Heart, Lung, and Blood Institute. His team also found that even mild psoriasis may indicate an increased risk for heart attack and stroke. Just one psoriasis skin patch, or plaque, "might be biologically active, causing low-grade inflammation and starting a cascade, speeding up their blood vessel disease," Mehta said. "People really should know that psoriasis is not just a cosmetic disease," he added. However, these study findings only show an association between psoriasis and blood vessel inflammation, not a direct cause-and-effect relationship, Mehta said. His ... Read more

Related support groups: Methotrexate, Psoriasis, Inflammatory Conditions, Coronary Artery Disease (CAD), Plaque Psoriasis, Acute Coronary Syndrome, Soriatane, Dovonex, Tazorac, Oxsoralen, Taclonex, Tazarotene, Acitretin, Calcipotriene, Dritho-Scalp, Resorcinol, Acute Coronary Syndrome - Prophylaxis, Anthralin, Vectical, Methotrexate LPF Sodium

Psoriasis, Depression Often Go Hand in Hand: Study

Posted 1 Oct 2015 by Drugs.com

THURSDAY, Oct. 1, 2015 – Regardless of severity, patients with the often disfiguring skin condition psoriasis face an elevated risk for depression, new research suggests. The depression risk may be driven more by concerns about appearance than by the actual status of the skin, said study author Dr. Roger Ho, an assistant professor in the department of dermatology at New York University School of Medicine. "One small area of [psoriasis] involvement might mean a lot more to one person than an area three times the size for another person," said Ho. "I think the location of skin lesions, such as lesions in a more visible area or lesions in an area that impairs daily functioning, might play a bigger role." Between 2 percent and 4 percent of North Americans have psoriasis, Ho said. The autoimmune disorder causes red, raised patches of skin covered with silvery-white scales. These patches ... Read more

Related support groups: Depression, Major Depressive Disorder, Psoriasis, Psoriatic Arthritis, Postpartum Depression, Dysthymia, Plaque Psoriasis, Psoriatic Arthropathy

2 Experimental Drugs Offer Hope Against Psoriasis: Studies

Posted 30 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 30, 2015 – Two experimental drugs show promise in treating psoriasis and a related condition, psoriatic arthritis, new studies report. The drugs, brodalumab and secukinumab (Cosentyx), represent a new approach to treatment, said Michael Siegel, director of research programs at the National Psoriasis Foundation. "These studies show how targeting parts of the immune system can have great effects, and that's really exciting for our patients," said Siegel, who wasn't involved in the research. Psoriasis, a chronic autoimmune condition, causes raised red patches of skin topped with silvery scales. These patches usually appear on the scalp, elbows, knees, face, lower back, hands and feet. Psoriatic arthritis is a form of the disease that includes joint pain, stiffness and swelling. The study findings appear in the Oct. 1 issue of the New England Journal of Medicine. In one ... Read more

Related support groups: Psoriasis, Psoriatic Arthritis, Plaque Psoriasis, Cosentyx, Secukinumab, Psoriatic Arthropathy

Psoriasis Linked to Higher Risk of Depression

Posted 20 Aug 2015 by Drugs.com

THURSDAY, Aug. 20, 2015 – People with psoriasis may be twice as likely to experience depression as those without the common skin condition, regardless of its severity, a new study suggests. "Psoriasis in general is a pretty visible disease," said study author Dr. Roger Ho, an assistant professor of dermatology at New York University School of Medicine in New York City. "Psoriasis patients are fearful of the public's stigmatization of this visible disease and are worried about how people who are unfamiliar with the disease may perceive them or interact with them." Genetic or biologic factors may also play a role in the link between depression and psoriasis, which requires more research, he said. Either way, the findings mean that all individuals with psoriasis could benefit from screening for depression, Ho said, and their friends and family members should be aware of the connection as ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Wellbutrin, Effexor, Prozac, Celexa, Paxil, Citalopram, Trazodone, Pristiq, Sertraline, Major Depressive Disorder, Viibryd, Amitriptyline, Fluoxetine, Bupropion, Effexor XR, Venlafaxine

Psoriasis Drug May Help Preserve Pancreas Cells in Type 1 Diabetes

Posted 21 Jul 2015 by Drugs.com

TUESDAY, July 21, 2015 – Taking two 12-week courses of alefacept – a drug already approved to treat the skin condition psoriasis – may help people with newly diagnosed type 1 diabetes preserve some function in the beta cells in the pancreas, a new study suggests. People taking the drug needed about 25 percent less insulin, and they had about half the rate of major low blood sugar episodes (hypoglycemia) compared to those who took a placebo, the study revealed. "This is the first time that documented rates of hypoglycemia – using standardized home glucometers in all patients – have shown a reduction in major hypoglycemia events following an immune intervention in new-onset [type 1 diabetes] patients," lead researcher Dr. Mario Ehlers, of the Immune Tolerance Network, said in a network news release. "This is important because frequent hypoglycemia is a common and serious complication ... Read more

Related support groups: Psoriasis, Diabetes, Type 1, Plaque Psoriasis, Amevive, Alefacept

Experimental Psoriasis Drug Shows Promise

Posted 8 Jul 2015 by Drugs.com

WEDNESDAY, July 8, 2015 – Preliminary trial results suggest that an experimental psoriasis drug may control the chronic skin disease better than the current standard treatment. The drug, guselkumab, was compared to the commonly used medication adalimumab (Humira, Enbrel) in a study involving nearly 300 patients with plaque psoriasis. Up to 86 percent of patients who received guselkumab cleared their psoriasis or had minimal psoriasis after 16 weeks of treatment, compared to 58 percent of patients taking adalimumab, the researchers reported. However, patients getting guselkumab were somewhat more prone to infections, the researchers said. "As a dermatologist, I am particularly excited about the potential of guselkumab and what this investigational therapy may mean for patients and the treatment of moderate to severe plaque psoriasis in the future," said lead researcher Dr. Kristian ... Read more

Related support groups: Psoriasis, Humira, Plaque Psoriasis, Adalimumab

New Drug Shows Promise Against Psoriasis

Posted 16 Jun 2015 by Drugs.com

TUESDAY, June 16, 2015 – Many patients with the skin disease psoriasis showed significant improvement when taking an experimental drug called ixekizumab, according to a late-stage, phase 3 clinical trial. "The visible effects of psoriasis can have a major and life-ruining impact on people's confidence and self-esteem," study leader Chris Griffiths, a professor of dermatology at the University of Manchester in England, said in a university news release. "What we saw in this trial was not just the physical aspects of the disease clearing up, but people on the new drug also reporting a marked improvement in their quality of life as they felt more confident and suffered less from itching – far more than in the other two groups," he said. The trial was funded by drug maker Eli Lilly and included 2,500 patients with moderate-to-severe psoriasis. Half took ixekizumab, while the other half ... Read more

Related support groups: Psoriasis, Plaque Psoriasis

Injuries Up Risk of Psoriatic Arthritis for People With Psoriasis

Posted 12 Jun 2015 by Drugs.com

FRIDAY, June 12, 2015 – Injuries increase the risk of psoriatic arthritis in people who have psoriasis, a new study suggests. Psoriatic arthritis – chronic arthritis associated with the skin condition psoriasis – can lead to severe, disabling joint damage. About 30 percent of people with psoriasis develop psoriatic arthritis, according to the researchers. The study included information collected between 1995 and 2013. The information was from more than 70,000 psoriasis patients, including more than 15,000 who suffered physical injury. During that time, more than 1,000 cases of psoriatic arthritis were diagnosed. The incidence rate of psoriatic arthritis was 30 per 10,000 person-years among those who had a physical injury. In people without injury, the rate of psoriatic arthritis was 22 per 10,000 person-years. The increased risk of psoriatic arthritis associated with injury was even ... Read more

Related support groups: Psoriasis, Psoriatic Arthritis

Ingredient in MS, Psoriasis Drugs Linked to Two Deadly Brain Infections

Posted 9 Apr 2015 by Drugs.com

WEDNESDAY, April 8, 2015 – An active ingredient in some psoriasis and multiple sclerosis medications has been linked to two cases of a rare and sometimes lethal brain infection. The ingredient, dimethyl fumarate, appears to have contributed to the deaths of two European women. The women contracted progressive multifocal leukoencephalopathy, or PML, according to two letters published in the April 9 issue of the New England Journal of Medicine. One case involved a 54-year-old woman with multiple sclerosis. She died in October 2014 from complications related to PML and pneumonia, following 4.5 years of treatment with a time-delayed form of dimethyl fumarate carrying the brand name Tecfidera, researchers reported. The second case was a 64-year-old woman with psoriasis. She died in August 2014 from PML after being treated with a delayed-release dimethyl fumarate compound with the brand name ... Read more

Related support groups: Multiple Sclerosis, Psoriasis, Tecfidera, Dimethyl Fumarate

Health Tip: Spot the Symptoms of Scalp Psoriasis

Posted 11 Mar 2015 by Drugs.com

-- Scalp psoriasis may be confused with dandruff, but the two conditions can cause a host of differing symptoms. The American Academy of Dermatology says unique signs of scalp psoriasis may include: Patches of skin on the scalp that may be thick and inflamed. Bleeding from scratching the scalp. Extreme tenderness or a burning sensation on the scalp. Temporary hair loss. Read more

Related support groups: Psoriasis

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