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Platelet Aggregation Inhibition Blog

Daily Aspirin Regimen Not Safe for Everyone, FDA Warns

Posted 6 May 2014 by Drugs.com

TUESDAY, May 6, 2014 – Taking an aspirin a day can help prevent heart attack and stroke in people who have suffered such health crises in the past, but not in people who have never had heart problems, according to the U.S. Food and Drug Administration. "Since the 1990s, clinical data have shown that in people who have experienced a heart attack, stroke or who have a disease of the blood vessels in the heart, a daily low dose of aspirin can help prevent a reoccurrence," Dr. Robert Temple, deputy director for clinical science at the FDA, said in an agency news release. A low-dose tablet contains 80 milligrams (mg) of aspirin, compared with 325 mg in a regular strength tablet. However, an analysis of data from major studies does not support the use of aspirin as a preventive medicine in people who have not had a heart attack, stroke or heart problems. In these people, aspirin provides no ... Read more

Related support groups: Aspirin, Ischemic Stroke, Excedrin, Aggrenox, Alka-Seltzer, Fiorinal, Ecotrin, Excedrin Migraine, Platelet Aggregation Inhibition, Arthritis Pain Formula, Fiorinal with Codeine, Norgesic, Bayer Aspirin, Percodan, Soma Compound, Cardiovascular Risk Reduction, Norgesic Forte, Excedrin Extra Strength, Levacet, Excedrin Back & Body

Aspirin Equals Pricier Blood Thinner for Preventing Clots: Study

Posted 4 Jun 2013 by Drugs.com

TUESDAY, June 4 – Aspirin appears to be just as good as more expensive, more potent blood-thinning medication for preventing blood clots after hip replacement surgery, according to new research. People who get artificial hips are at risk of serious blood clots, such as deep vein thrombosis and pulmonary embolism, after the surgery. To prevent them, doctors usually prescribe blood-thinning (anticoagulant) medications, such as low-molecular-weight heparin, which is given by injection, or the newer drug, rivaroxaban (brand name Xarelto), a pill. But that old medicine-cabinet standby, aspirin, also has blood-thinning properties. And the Canadian researchers wondered if this simple, inexpensive drug could also prevent blood clots after a major surgery. They compared the drugs for four weeks, following 10 days of treatment with heparin immediately post-surgery. The investigators found the ... Read more

Related support groups: Aspirin, Ecotrin, Platelet Aggregation Inhibition, Bayer Aspirin, Bufferin, Low Dose ASA, Aspergum, Buffered Aspirin, Easprin, Ascriptin Enteric, St Joseph Aspirin, Aspir-Low, ZORprin, Norwich Aspirin, Gennin-FC, Bayer Childrens Aspirin, Ecotrin Maximum Strength, Halfprin, Ecpirin, Buffasal

Double-Dose Plavix Benefits Certain Patients, Study Finds

Posted 2 Sep 2010 by Drugs.com

WEDNESDAY, Sept. 1 – More isn't necessarily better when prescribing the two drugs commonly used to treat patients who are in danger of having a heart attack, Plavix (clopidogrel) and aspirin, a new study suggests. Two reports on the data find that high doses of Plavix are good for some patients, but not all, while high-dose aspirin is no better than a low dose for preventing new heart attacks, other cardiac problems, stroke and death. The findings suggest a need to assess the risks and benefits individually, experts say. Patients who are at high risk for heart attack and stroke and low risk for bleeding are going to do well on a higher dose of Plavix, said Dr. Gregg Stone, author of an editorial in The Lancet. "Patients who are at lower risk for atherosclerotic complications, but high risk for bleeding should be treated with a more conservative lower dose," added Stone, director of ... Read more

Related support groups: Aspirin, Plavix, Ecotrin, Platelet Aggregation Inhibition, Bayer Aspirin, Bufferin, Low Dose ASA, Aspergum, Buffered Aspirin, Easprin, Ascriptin Enteric, ZORprin, Aspir-Low, St Joseph Aspirin, Norwich Aspirin, Gennin-FC, Bayer Childrens Aspirin, Ecotrin Maximum Strength, Sloprin, Halfprin

Research Sheds Light on Increased Blood Clot Risk

Posted 24 Jun 2010 by Drugs.com

THURSDAY, June 24 – In an effort to uncover why some people's blood platelets clump faster than others, a genetic analysis has turned up a specific grouping of overactive genes that seems to control the process. On the plus side, platelets are critical for fending off infections and healing wounds. On the down side, they can hasten heart disease, heart attacks and stroke, the study authors noted. The current finding regarding the genetic roots driving platelet behavior comes from what is believed to be the largest review of the human genetic code to date, according to co-senior study investigator Dr. Lewis Becker, a cardiologist with the Johns Hopkins University School of Medicine. "Our results give us a clear set of new molecular targets, the proteins produced from these genes, to develop tests that could help us identify people more at risk for blood clots and for whom certain ... Read more

Related support groups: Platelet Aggregation Inhibition

Newer Blood Thinner Beats Plavix for Bypass Patients

Posted 16 Mar 2010 by Drugs.com

TUESDAY, March 16 – In a trial comparing two anti-clotting drugs, patients given Brilinta before cardiac bypass surgery were less likely to die than those given Plavix, researchers found. Both drugs prevent platelets from clumping and forming clots, but Plavix, the more popular drug, has been linked to potentially dangerous side effects in cancer patients. In addition, some people don't metabolize it well, making it less effective. "We did see about a 50 percent reduction in mortality in these patients [who took Brilinta], but without any increase in bleeding complications," Dr. Claes Held, an associate professor of cardiology at the Uppsala Clinical Research Center at Uppsala University in Sweden and the study's lead researcher, said during an afternoon press conference Tuesday. "Ticagrelor (Brilinta) in this setting, with acute coronary syndrome patients with the potential need for ... Read more

Related support groups: Plavix, Platelet Aggregation Inhibition, Acute Coronary Syndrome, Acute Coronary Syndrome - Prophylaxis

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Plavix, clopidogrel