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Study Explores Distraction's Role in Pain Relief

Posted 11 days ago by Drugs.com

THURSDAY, May 17 – Mental distractions can act as a form of pain relief, according to a new study. Study volunteers were asked to complete a difficult or easy memory task while a painful level of heat was applied to their arms. The participants perceived less pain when they were more distracted by the harder of the two memory tasks. Using functional MRI, the German researchers also found that the lower levels of pain were associated with reduced activity in the spinal cord. The study appears May 17 in the journal Current Biology. The findings show that the reduced pain associated with distraction isn't just a mental process, but also a physical mechanism that reduces the amount of pain signals traveling from the spinal cord to the brain, said study author Christian Sprenger of the University Medical Center Hamburg-Eppendorf, in a journal news release. The pain-reducing effects of ... Read more

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FDA Medwatch Alert: Hydromorphone Hydrochloride Injection 1 MG/ML, (C-II) 1 ML Fill In 2.5 ML Carpuject: Recall - May Contain More Than the Intended Fill Volume

Posted 14 days ago by Drugs.com

ISSUE: Hospira, Inc. notified healthcare professionals of a recall of one lot of Hydromorphone Hydrochloride Injection 1 MG/ML, due to reports of a single Carpuject containing more than the 1 mL labeled fill volume. Opioid pain medications such as Hydromorphone have life-threatening consequences if overdosed, including respiratory depression (slowed breathing or suspension of breathing), low blood pressure, and reduced heart rate including circulatory collapse. The affected lot number is 07547LL, with an expiration date of July 1, 2013. The affected lot was distributed in September – October 2011. It was initially distributed to wholesalers and a limited number of hospitals in Alaska, Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Delaware, Florida, Indiana, Louisiana, Maryland, Massachusetts, Minnesota, Missouri, Mississippi, North Carolina, New Hampshire, N ... Read more

Related support groups: Pain, Dilaudid, Hydromorphone, Exalgo, Hydromorph Contin, Dilaudid-HP, Palladone, Hydrostat IR

Kids Most Likely to Start Abusing Painkillers at 16: Study

Posted 7 May 2012 by Drugs.com

MONDAY, May 7 – Among U.S. adolescents, misuse of prescription painkillers peaks at age 16, earlier than thought, a new large survey analysis reveals. "What our findings suggest is that if we wait until the last year of high school or college to take some kind of action that could prevent the misuse of opioid painkillers, it'll be a case of too little, too late," cautioned study co-author James Anthony, a professor of epidemiology and biostatistics in the department of epidemiology and biostatistics at Michigan State University in East Lansing. Many experts consider "extramedical" painkiller abuse – taking pain drugs such as OxyContin (oxycodone) and Vicodin (hydrocodone) to get high rather than to relieve extreme pain – the country's most serious drug challenge. Some kids had already misused these drugs by age 13 or 14, or eighth grade, the researchers found. Anthony and his ... Read more

Related support groups: Pain, Suboxone, Methadone, Oxycodone, Percocet, OxyContin, Hydrocodone, Vicodin, Morphine, Norco, Fentanyl, Lortab, Subutex, Opana, Codeine

Adjusting Your Attitude About Chronic Pain May Help You Sleep

Posted 27 Apr 2012 by Drugs.com

FRIDAY, April 27 – People with chronic pain who learn to think less about their pain may be able to sleep better, according to a new study. They may also reduce their pain on a daily basis. The study included 214 people with chronic jaw and face pain, often considered to be stress related. The patients were white females, whose average age was 34. The patients filled out questionnaires about sleep quality, depression, their pain levels and emotional responses, including whether they think about their pain often or exaggerate it. The researchers said that such negative thinking was directly linked to both poor sleep and worse pain. "We have found that people who ruminate about their pain and have more negative thoughts about their pain don't sleep as well, and the result is they feel more pain," study leader Luis Buenaver, an assistant professor of psychiatry and behavioral sciences at ... Read more

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Fatigue Not a Factor in Fibromyalgia Pain, Study Says

Posted 26 Apr 2012 by Drugs.com

THURSDAY, April 26 – Poor sleep is not a significant predictor of pain intensity and duration in patients with fibromyalgia, a new study says. Fibromyalgia patients often have difficulty sleeping, and University of Florida researchers wanted to determine whether lack of sleep is associated with higher levels of pain in these patients. The study included 74 adults with fibromyalgia who were followed for 14 days. The patients kept sleep diaries describing each night's sleep, and rated their pain every evening. The results showed that the four measures of sleep used in the study failed to predict pain levels. The effects of impaired sleep, such as fatigue and inactivity, may play more important roles in fibromyalgia patients' pain levels than sleep duration or insomnia, the researchers said. The study appears in the current issue of The Journal of Pain. Previous research has shown that ... Read more

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FDA Medwatch Alert: Morphine Sulfate Injection USP, 4 mg/mL (C-II), 1 mL fill in 2.5 mL Carpuject by Hospira, Inc: Recall - May Contain More Than Intended Fill Volume

Posted 18 Apr 2012 by Drugs.com

ISSUE: Customer report of two Carpujects syringes containing more than the 1 mL labeled fill volume. Opioid pain medications such as morphine have life-threatening consequences if overdosed. Those consequences can include respiratory depression (slowed breathing or suspension of breathing), and low blood pressure. BACKGROUND: The affected product is a prefilled glass cartridge for use with the Carpuject Syringe system. The affected lot number is 10830LL, with an expiration date of April 1, 2013. Morphine Sulfate Carpujects 4 mg/mL are packaged in Slim-Pak tamper detection packages with each box containing 10 Carpujects (NDC 0409-1258-30). The affected lot was distributed in January 2012. It was initially distributed to wholesalers and a limited number of hospitals in Arizona, Colorado, Hawaii, Illinois, Indiana, Michigan, Minnesota, Ohio, Texas and Virginia. RECOMMENDATION: Anyone ... Read more

Seniors' Long-Term Use of Strong Painkillers a Concern

Posted 12 Mar 2012 by Drugs.com

MONDAY, March 12 – Older patients prescribed narcotic painkiller drugs, such as codeine or oxycodone, soon after short-stay surgery are at increased risk of becoming long-term users, a new study finds. Canadian researchers looked at data from almost 400,000 patients aged 66 and older who had short-stay surgery for cataracts, gallbladder removal, prostate tissue removal or varicose vein stripping. Of those patients, almost 28,000 (more than 7 percent) were prescribed narcotic painkillers, also called opioids, within seven days after hospital discharge. More than 30,000 (nearly 8 percent) were prescribed opioids one year after surgery. Almost 3,000 (more than 10 percent) of patients from both groups were identified as long-term opioid users one year after surgery. Patients who received an opioid prescription within seven days of surgery were about 44 percent more likely to become ... Read more

FDA Panel to Weigh Second Chance for New Class of Painkillers

Posted 12 Mar 2012 by Drugs.com

MONDAY, March 12 – A U.S. Food and Drug Administration advisory panel on Monday will weigh the wisdom of allowing new clinical trials of a class of powerful painkillers for osteoarthritis. The drugs may have worked so well for some patients that those patients wound up needing knee replacement surgery because they overworked their already damaged joints. Studies of these painkillers were halted in 2010 because of this troubling side effect, and at the time Dr. Nancy Lane, lead researcher on a trial looking at one of these drugs, tanezumab, said patients who ended up needing a knee replacement most likely harmed their damaged joint even further because they felt so good. "They probably accelerated the degeneration of the joint," said Lane, director of the Aging Center, Medicine and Rheumatology, at the University of California, Davis. "Sometimes, pain is good in protecting you." ... Read more

Related support groups: Pain, Osteoarthritis

People in Poor Neighborhoods Have More Pain, Study Finds

Posted 8 Mar 2012 by Drugs.com

THURSDAY, March 8 – Adults under the age of 50 who live in low-income neighborhoods experience more chronic pain than those in more affluent communities, new research finds. Blacks, however, experienced more chronic pain and disability than whites regardless of where they lived, according to the researchers from the University of Michigan. The study, published in a recent issue of The Journal of Pain, included more than 3,700 adults under age 50. Men and women who lived in poorer neighborhoods had more pain, pain-related disability and mood disorders, such as depression and anxiety, the investigators found. The link between pain and the economic status of a neighborhood was especially strong among young black Americans, the study authors pointed out. "Our findings show an unequal burden of pain in blacks and among those living in poor neighborhoods among the 116 million adults who ... Read more

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Pain Intensity Greater for Women Than Men, Study Finds

Posted 23 Jan 2012 by Drugs.com

MONDAY, Jan. 23 – According to the results of a study in which researchers examined pain scores from tens of thousands of patients in the United States, women experience more intense pain than men. The findings, published in the Jan. 23 issue of the Journal of Pain, suggest that greater effort is needed to recruit women into studies in order to determine the reasons for this gender difference, the Stanford University School of Medicine investigators said. For the study, the researchers analyzed electronic medical records to examine more than 160,000 pain scores reported for more than 72,000 adult patients. The results showed higher pain scores for women in virtually every disease category. The differences were both statistically and clinically significant, the authors noted in a Stanford news release. "In many cases, the reported difference approached a full point on the 1-to-10 scale. ... Read more

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Insys Therapeutics Announces FDA Approval of Subsys Fentanyl Sublingual Spray

Posted 12 Jan 2012 by Drugs.com

PHOENIX, Jan 5, 2012 - INSYS Therapeutics announces the US Food and Drug Administration approval of its branded breakthrough cancer pain medication, Subsys fentanyl sublingual spray. SUBSYS is a sublingually-administered formulation of fentanyl in a novel delivery device which offers numerous benefits to patients that experience episodes of breakthrough cancer pain. Breakthrough cancer pain is characterized by sudden, often unpredictable, episodes of intense pain which can peak in severity at three to five minutes despite background pain medication. Subsys is approved in cancer patients 18 years of age and older who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain. "INSYS is proud and excited to have Subsys approved," said Dr. Larry Dillaha, MD, Chief Medical Officer of INSYS Therapeutics. "INSYS was founded as a specialty ... Read more

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FDA Warns of Painkiller Mix-Up at Nebraska Plant

Posted 9 Jan 2012 by Drugs.com

MONDAY, Jan. 9 – The U.S. Food and Drug Administration issued a warning on Monday that some narcotic prescription painkillers made at a Nebraska plant may have been mixed up with some over-the-counter medicines packaged at the same facility. "We issued a public health advisory to health care professionals and patients about a potential problem with opioid products manufactured and packaged for Endo Pharmaceuticals by Novartis Consumer Health at its Lincoln, Nebraska, site," Dr. Edward Cox, director of the FDA's Office of Antiviral Products in the Office of New Drugs at the Center for Drug Evaluation and Research, said during a morning news conference. On Sunday, Novartis issued a recall for some over-the-counter medications made at the same plant. These included Excedrin, NoDoz, Bufferin and Gas-X, Cox said. "Mixing of different products in the same bottle could result in consumers ... Read more

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Crowding in ER May Delay Pain Relief for Kids

Posted 30 Dec 2011 by Drugs.com

THURSDAY, Dec. 29 – Overcrowding in emergency rooms appears to keep children with broken arms and legs from getting pain relief in a timely manner, according to a new study. Researchers from the University of Colorado School of Medicine said their findings are significant since these injuries, known as long bone fractures, are common among children and very painful. "Pain associated with long bone fractures can be pretty severe," study author Dr. Marion Sills said in a university news release. "But crowded emergency departments are impacting the delivery of care on many levels, including the delivery of pain medication." In conducting the study, published in the December issue of the journal Academic Emergency Medicine, researchers examined 1,229 children treated in an ER over the course of one year. They found the children were 4 percent to 47 percent less likely to receive treatment ... Read more

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Spouse's Reaction May Affect Pain Management

Posted 16 Dec 2011 by Drugs.com

FRIDAY, Dec. 16 – Chronic pain can hinder communication between spouses, which, in turn, can impair the affected partner's ability to cope with the pain, according to a new study. Previous research has shown that validation of a spouse's emotions (showing respect and acceptance) promotes emotional control, trust and closeness, while invalidation of emotions (showing hostility or no interest) increases emotional distance and is associated with poor adjustment within the marriage and depression. This new study included 78 U.S. adults with chronic pain and their spouses. Women accounted for 58 percent of the spouses with pain. Low back pain was the most common type of major pain and the leading diagnoses were osteoarthritis, disc problems and fibromyalgia. The participants were interviewed for three hours, with the final 15 minutes focused on a difficult topic, such as family finances. ... Read more

Related support groups: Pain, Fibromyalgia, Osteoarthritis

Opioids May Be Overused for Chronic Stomach Pain

Posted 2 Dec 2011 by Drugs.com

FRIDAY, Dec. 2 – Prescriptions for opioid painkillers to treat chronic abdominal pain more than doubled in the United States between 1997 and 2008, according to a new study. This large increase of prescriptions written at outpatient clinics is concerning for several reasons, said lead author Dr. Spencer Dorn, an assistant professor of medicine at the University of North Carolina Medical School at Chapel Hill, and colleagues. Very little evidence exists to support the use of opioids to treat chronic pain that isn't cancer related, and opioids are frequently misused and sometimes abused, Dorn said. Extended use of opioids can trigger other gastrointestinal symptoms such as nausea, vomiting and constipation, and may even worsen abdominal pain, he added. The study appears in the December issue of the journal Clinical Gastroenterology and Hepatology. Chronic abdominal pain is a common ... Read more

Related support groups: Pain, Methadone, Oxycodone, OxyContin, Hydrocodone, Morphine, Fentanyl, Subutex, Opana, Codeine, Dilaudid, Opana ER, Roxicodone, MS Contin, Nucynta

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