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Could 'Phone Care' Ring in New Approach to Pain Relief?

Posted 7 days ago by Drugs.com

TUESDAY, July 15, 2014 – Relief for chronic pain may be just a phone call away, according to a new study. Pain is a major health problem in the United States and costs the country more than $600 billion each year in lost productivity and health care. For this study, published in the July 16 issue of the Journal of the American Medical Association, researchers evaluated telephone-delivered care within a group of 250 people with chronic musculoskeletal pain. Participants were randomly assigned to receive either usual care from their primary care doctors or "telecare" management, which included automated symptom monitoring and use of pain medications guided by scientific methods. After 12 months, more than half the patients in the telecare group reported at least a 30 percent improvement in their pain score, compared with about one-quarter of those in the usual-care group, the study ... Read more

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Prescriptions for Powerful Painkillers Vary Widely Among States: CDC

Posted 1 Jul 2014 by Drugs.com

TUESDAY, July 1, 2014 – Doctors in some states seem to wield a freer hand issuing prescriptions for powerful narcotic medications, leading to wide variations in narcotic drug use among states, U.S. health officials reported Tuesday. Physicians in Alabama – the state with the highest number of narcotic painkiller prescriptions – issued nearly three times as many of those prescriptions as doctors in Hawaii – the lowest prescribing state, according to researchers with the Centers for Disease Control and Prevention. "The bottom line is we're not seeing consistent, effective, appropriate prescribing of painkillers across the nation, and this is a problem because of the deaths that result," Dr. Tom Frieden, director of the CDC, said at a news conference. Frieden added that every day 46 people die from an overdose of prescription painkillers. Overall, health-care providers wrote 259 ... Read more

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Use Prescription Painkillers Safely

Posted 8 Jun 2014 by Drugs.com

FRIDAY, June 6, 2014 – Powerful prescription painkillers known as opioids are often involved in accidental overdoses, so experts offer tips on how to take these highly addictive medications safely. "Prescription painkiller misuse is a growing epidemic. However, most people who abuse these drugs are struggling with an addiction they never intended to have," said John Ulczycki, vice president of strategic initiatives at the National Safety Council. "This National Safety Month, we hope to educate Americans on proper use so they can relieve pain without the tragic consequences of drug dependence or death." Dr. Don Teater, a medical advisor at the National Safety Council provided the following five tips to help ensure the safe use of prescription painkillers: Consider other options. Talk to your doctor about other medications that may be more effective in controlling your pain. In most ... Read more

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Men Feel More Pain After Major Surgeries, Study Finds

Posted 3 Jun 2014 by Drugs.com

TUESDAY, June 3, 2014 – Gender may play a part in how much pain a patient feels following surgery, new research suggests. An Austrian study involving more than 10,000 people found that men experience more pain after major surgery, while women report feeling more pain following minor procedures, such as biopsies. "The influence of gender and sexes is a key issue of today's research in medicine. However, current literature in the field of perioperative medicine rarely focuses on this question," study co-author Dr. Andreas Sandner-Kiesling, of the department of anesthesiology & intensive care at the Medical University of Graz, Austria, said in a university news release. "Our aim was to analyze a large population to find differences in postoperative pain perception in females and males," Sandner-Kiesling explained. The patients involved in the four-year study were interviewed 24 hours ... Read more

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FDA Medwatch Alert: Epidural Corticosteroid Injection: Drug Safety Communication - Risk of Rare But Serious Neurologic Problems

Posted 23 Apr 2014 by Drugs.com

Including methylprednisolone, hydrocortisone, triamcinolone, betamethasone, and dexamethasone [Posted 04/23/2014] ISSUE: FDA is warning that injection of corticosteroids into the epidural space of the spine may result in rare but serious adverse events, including loss of vision, stroke, paralysis, and death. The injections are given to treat neck and back pain, and radiating pain in the arms and legs. The effectiveness and safety of epidural administration of corticosteroids have not been established, and FDA has not approved corticosteroids for this use.  FDA is requiring the addition of a Warning to the drug labels of injectable corticosteroids to describe these risks. BACKGROUND: To raise awareness of the risks of epidural corticosteroid injections in the medical community, FDA’s Safe Use Initiative convened a panel of experts, including pain management experts to help define the te ... Read more

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Too Much Codeine Still Prescribed to U.S. Kids: Study

Posted 21 Apr 2014 by Drugs.com

MONDAY, April 21, 2014 – Emergency room physicians still hand out hundreds of thousands of codeine prescriptions for children every year, despite warnings that kids' responses to codeine vary wildly and the drug can cause an accidental overdose, a new study finds. ER doctors issued about 560,000 to 880,000 prescriptions for codeine to kids each year between 2001 and 2010, according to an analysis of hospital survey data collected annually by the U.S. Centers for Disease Control and Prevention. "We have hundreds of thousands of children still getting codeine, even though there are better and safer alternatives available," said study author Dr. Sunitha Kaiser, an assistant clinical professor of pediatrics at the University of California, San Francisco (UCSF). The study was published online April 21 in the journal Pediatrics. These prescriptions continued to be handed out despite repeated ... Read more

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ERs Dispensing More Narcotic Painkillers: Study

Posted 23 Mar 2014 by Drugs.com

FRIDAY, March 21, 2014 – More and more Americans are being prescribed powerful narcotic drugs when they visit the emergency department for problems such as low back pain or a pounding headache, a new study finds. Between 2001 and 2010, emergency departments in the United States showed a 49 percent increase in prescriptions for narcotic painkillers – also known as opiates. That was despite the fact that there was only a small increase in the percentage of visits for painful conditions. Experts said the trend is concerning because narcotic painkillers – which include drugs like OxyContin, Percocet and Vicodin – can be addictive, or abused by people with existing drug problems. And while the drugs may be necessary for more-severe pain, ER doctors see many patients who can stick with over-the-counter pain relievers. "In many cases, naproxen, Tylenol (acetaminophen) and ibuprofen are the ... Read more

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Pain Can Plague Women After Knee Replacement Surgery

Posted 13 Mar 2014 by Drugs.com

THURSDAY, March 13, 2014 – Women with certain kinds of arthritis are among groups of patients who are most vulnerable to serious pain after undergoing knee replacement surgery, a new study finds. General anesthesia and longer time in a tourniquet also appear to contribute to higher levels of pain, the study authors said. "There is no question that pain after total knee replacement is greater than that after total hip replacement," Dr. Thomas Sculco, surgeon-in-chief at New York City's Hospital for Special Surgery, said in a hospital news release. "Many factors play a role, and our studies found that younger female patients, particularly those with post-traumatic or rheumatoid arthritis, had the highest pain scores." Sculco and his colleagues examined the medical records of 273 patients who underwent total knee replacement procedures from 2007 to 2010. Those who suffered the most pain ... Read more

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FDA Approves Xartemis XR (oxycodone hydrochloride and acetaminophen) Extended-Release Tablets (CII)

Posted 12 Mar 2014 by Drugs.com

DUBLIN--(BUSINESS WIRE)--Mar. 12, 2014-- Mallinckrodt plc today announced that the U.S. Food and Drug Administration (FDA) has approved Xartemis XR (oxycodone hydrochloride and acetaminophen) Extended-Release Tablets (CII), previously known as MNK-795, for the management of acute pain severe enough to require opioid treatment and in patients for whom alternative treatment options (e.g., non-opioid analgesics) are ineffective, not tolerated or would otherwise be inadequate. Xartemis XR is the first and only extended-release oral combination of two clinically proven pain medications – oxycodone and acetaminophen. Xartemis XR has both immediate- and extended-release components: formulated to provide onset of pain relief in less than one hour and to allow twice daily dosing. The product’s release profile combines Mallinckrodt’s newly patented technology, including design, formulation, pha ... Read more

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Hormones Might Offer Relief From Chronic Pain, Small Study Suggests

Posted 10 Mar 2014 by Drugs.com

SATURDAY, March 8, 2014 – A combination of two hormones might make a difference in reducing suffering in people with chronic pain, according to a small, preliminary study. Seven of 9 patients reported a 30 percent to 40 percent decrease in pain after taking doses of oxytocin and human chorionic gonadotropin, the researchers found. In addition, the level of opioid (narcotic) painkillers needed by these seven patients also declined by 30 percent to 40 percent. Patients also reported improvement in the intensity of pain flare-ups and longer time between flares, the study authors said. Oxytocin is known as the "love hormone" and has been linked to positive human emotions. Human chorionic gonadotropin plays a role during pregnancy. Levels of both hormones increase during and after childbirth, and they're thought to contribute to lower levels of pain in pregnant women. Study author Dr. ... Read more

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Groups Push FDA to Revoke Approval of Highly Potent Painkiller

Posted 26 Feb 2014 by Drugs.com

WEDNESDAY, Feb. 26, 2014 – Dozens of experts and health care agencies sent a letter this week urging that the U.S. Food and Drug Administration revoke its approval of the supercharged painkiller, Zohydro ER. In the petition sent to the FDA on Wednesday, more than 40 consumer watchdog groups, addiction treatment groups and others noted that the drug was approved despite significant resistance from the FDA's own advisory committee, which voted 11-2 against allowing Zohydro ER to be sold. According to consumer advocate group Public Citizen, which issued its own news release on the issue Wednesday, a single dose of Zohydro ER could kill a child. The petition to the FDA warns that the painkiller is simply too dangerous and there's no need for another high-dose opioid (prescription narcotic) painkiller. "I'm amazed that the FDA would approve a dangerous new [medicine] over the strong ... Read more

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Most Teens With Fibromyalgia Suffer Pain, Fatigue as Adults

Posted 26 Feb 2014 by Drugs.com

WEDNESDAY, Feb. 26, 2014 – Four out of five teens suffering from juvenile fibromyalgia will continue to have pain and other symptoms in adulthood, a new study finds. About half of these children will end up as grown-ups with full-blown adult fibromyalgia, the researchers found. "Half of the former teens we studied met the full criteria for adult fibromyalgia, and another 35 percent of them continued to have symptoms of fatigue, pain and sleep difficulty, but did not meet all the criteria for fibromyalgia syndrome," said study author Susmita Kashikar-Zuck, research director in behavioral medicine and clinical psychology at Cincinnati Children's Hospital Medical Center. The study, published in the March print issue of Pediatrics, stemmed from research into juvenile fibromyalgia, Kashikar-Zuck said. Fibromyalgia is a mysterious disorder that causes muscle pain and fatigue. People with the ... Read more

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Amputee's 'Phantom Limb' Pain Eased by Virtual Arm Technology

Posted 25 Feb 2014 by Drugs.com

TUESDAY, Feb. 25, 2014 – A unique way to possibly treat the intense pain of phantom limb syndrome has been invented – by creating a virtual world for an amputee to enter via computer. Within that world, the patient controlled a "virtual arm" and apparently relieved his pain by tricking his brain into thinking his body was whole again, according to a new report. It's not clear if the virtual treatment will reduce pain in anyone else who suffers from the mysterious phantom limb condition, and no one knows if the effects are permanent. The cost isn't known, either. For now, however, the treatment has made a big difference in the life of the patient, who suffered from phantom limb pain for decades, the researchers said. "Pain stopped being a big part of his life," said study author Max Ortiz-Catalan, a graduate student in the division of biomedical engineering at Sweden's Chalmers ... Read more

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Iroko Pharmaceuticals Receives FDA Approval for Tivorbex

Posted 25 Feb 2014 by Drugs.com

PHILADELPHIA, FEBRUARY 24, 2014 — Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, today announced that the U.S. Food and Drug Administration (FDA) has approved Tivorbex (indomethacin) capsules, a nonsteroidal anti-inflammatory drug (NSAID), at 20 mg and 40 mg doses for the treatment of mild to moderate acute pain in adults1. Tivorbex was approved at dosage strengths that are 20 percent lower than the 25 mg and 50 mg indomethacin products currently on the market2. FDA approval of Tivorbex was supported by data from two Phase 3 multi-center, placebo-controlled trials that demonstrated significant improvement in pain relief in patients with post-surgical acute pain receiving Tivorbex compared with patients receiving placebo3. “The FDA approval of Tivorbex is another significant milestone for Iroko as it validates our s ... Read more

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Restless Sleep Linked to Widespread Pain in Older Adults

Posted 13 Feb 2014 by Drugs.com

THURSDAY, Feb. 13, 2014 – Waking up and not feeling rested isn't just annoying. Researchers say that "non-restorative sleep" is the biggest risk factor for the development of widespread pain in older adults. Widespread pain that affects different parts of the body – the main characteristic of fibromyalgia – affects 15 percent of women and 10 percent of men over age 50, according to previous studies. To identify the triggers of such widespread pain, British researchers compiled demographic data as well as information on the pain and physical and mental health of more than 4,300 adults older than 50. About 2,700 had some pain at the study's start, but none had widespread pain. The results, published Feb. 13 in Arthritis & Rheumatology, show that restless sleep as well as anxiety, memory problems and poor health play a role in the development of this type of pain. Three years after the ... Read more

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aspirin/diphenhydramine, aspirin/codeine, acetaminophen/caffeine/phenyltoloxamine, acetaminophen/caffeine/phenyltoloxamine/salicylamide, acetaminophen/dextromethorphan, acetaminophen/caffeine/magnesium salicylate/phenyltoloxamine, acetaminophen/aspirin/caffeine/salicylamide, acetaminophen/aluminum hydroxide/aspirin/caffeine/magnesium hydroxide, acetaminophen/aspirin, acetaminophen/dextromethorphan/doxylamine, acetaminophen/diphenhydramine, aspirin/caffeine/dihydrocodeine, aspirin/caffeine/salicylamide, aspirin/carisoprodol/codeine, aluminum hydroxide/aspirin/calcium carbonate/magnesium hydroxide, alfentanil, acetaminophen/guaifenesin, acetaminophen/phenyltoloxamine/salicylamide, bupivacaine liposome, capsaicin/lidocaine/menthol/methyl salicylate, Mapap Children's, Children's Silapap, Febrol Solution, Tolectin 600, Tolectin DS, Percocet 7.5/500, Numorphan, EC-Naprosyn, Duraclon, Astramorph PF, Buffasal, Hycet, Xylocaine Topical, Farbital, Capital w/Codeine, Medi-Seltzer, Percocet 2.5/325, Infumorph, Genapap, Aceta w/ Codeine, Mapap, Tylophen, Duraxin, acetaminophen/magnesium salicylate, Dolorex, Tylenol 8 Hour, Aspiritab, Lidosense 5, LMX 5, Oruvail, Indocin SR, IBU, Combunox, Remedol, Panamax 240, Norwich Aspirin, Acetylsalicylic Acid, Zero-Order Release, Stanback Analgesic, Therapy Bayer, Entaprin, Bufferin Extra Strength, YSP Aspirin, Aspirin Lite Coat, Roxanol 100, Rescudose, Morphine Rapi-Ject, Duramorph PF, Hydrostat IR, Duragesic-75, Ionsys, Tri-Buffered Aspirin, Minitabs, Sloprin, Halfprin, Empirin, Vanatrip, Tolectin, Paralyoc, Mapap Rapid Tabs, Bayer Plus, Buffex, Gennin-FC, Genprin, Litecoat Aspirin, Genacote, Extra Strength Bayer, Ecotrin Maximum Strength, Entercote, Doloral, Doloral Sirop, Outgro Pain Relief, Rid-A-Pain, Numorphan HCl, LTA II Kit, LTA Pediatric Kit, Senatec, LTA Preattached 360 Kit, Magan, Mobidin, Sarna Ultra, Sucrets, Wild Cherry, Dolorac, Prax, Tronothane, Nuprin Backache Caplet, Vistazine, Laryng-O-Jet Spray, LMX 4, PP-Cap, Anestacon, Lidomar, Endocodone, ETH-Oxydose, Morphitec, M-Oxy, Xylocaine 10% Oral, Dermaflex, LMX Plus, LMX 4 with Tegaderm, Ela-Max 5, Ela-Max, Medi-Quik Spray, Protech First Aid Stik, Paracetamol Zydus, Paracetamol Winthrop, Pain Clear Paracetamol, Setamol, Paraspen Drops, Sigma Pain Relief, Pharmore Paracetamol, Panadol Gel Caps, Pacimol Caplets, Panadol Colourfree Drops, Pharmaction Paracetamol, Febridol Infant Drops, Accidental Rapatabs, Lemsip Headcold, Sigma Paracetamol, Paracetamol Soluble, Hexal Comfarol, Panadol Extend, Priceline Paracetamol, Paracare, Cuprofen for Children, Mandanol Infant, Mandanol 6+, Silapap Infants, Parmol, Parahexal, Febridol, Duatrol SR, Mapap Meltaway, Panadol Gel Tabs, Panadol Mini Caps, Pharmacist Paracetamol, Promax, Dymadon, Mapap Arthritis Pain, Paraspen, Lemsip Original, Bydol, Geluprane, Paracetamol Almus, Paracetamol Arrow, Expandox, Efferalganodis, Dolotec, Efferalgan, Paracetamol Biogaran, Paracetamol EG, Paracetamol RPG, Paracetamol Sandoz, Paracetamol Teva, Paracetamol Ranbaxy, Paracetamol Qualimed, Paracetamol Ivax, Paracetamol Merck, Dolko Enfants, Dolko, Rex Paracetamol, Paineze Paracetamol, Panamol, Panadol Soluble, Panadol Rapid Handipak, Chem Mart Chemadol, Benylin Sore Throat, Tempol, Taminol, Doliprane Sans Sucre, Dolitabs, Doliprane Adultes, Doliprane, Claradol, Dafalgan, RT Capsin