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Related terms: Bladder Hyperactivity, Chronic overactivity of the bladder, Detrusor hyperreflexia, Detrusor instability, Incontinence, Urge, Irritable Bladder, Spasmodic Bladder, Unstable Bladder, Urge Incontinence, Urinary Frequency, OAB
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Overactive Bladder a Common Problem, FDA Says
Posted 8 days ago by Drugs.com
MONDAY, Jan. 19, 2015 – More than 33 million Americans suffer from overactive bladder, including 40 percent of women and 30 percent of men, the U.S. Food and Drug Administration says. There are numerous approved treatments for the condition, but many people don't seek help because they're embarrassed or don't know about therapy options, according to an agency news release. In people with overactive bladder, the bladder muscle squeezes too often or squeezes without warning. This can cause symptoms such as: the need to urinate too often (eight or more times a day, or two or more times a night); the need to urinate immediately; or accidental leakage of urine. Treatments for overactive bladder include oral medications, skin patches or gel, and bladder injections. "There are many treatment options for patients with overactive bladder. Not every drug is right for every patient," Dr. Olivia ... Read more
Related support groups: Overactive Bladder, Urinary Incontinence, Botox, Oxybutynin, VESIcare, Myrbetriq, Enablex, Ditropan, Detrol, Sanctura, Oxytrol, Detrol LA, Gelnique, Solifenacin, Trospium, Sanctura XR, Mirabegron, Tolterodine, Darifenacin, Ditropan XL
Drug for Bladder Problems May Help Control Weight, Too
Posted 7 Jan 2015 by Drugs.com
TUESDAY, Jan. 6, 2015 – A drug already used to treat overactive bladder may also someday help control weight by boosting the metabolic powers of brown fat, a small study suggests. While white fat stores energy, brown fat burns energy to generate body heat. In the process, it can help maintain body weight and prevent obesity, at least in animals, previous studies have shown. In the new study, researchers gave 12 healthy, lean young men a high dose of the drug mirabegron (Myrbetriq), and found that it boosted their metabolic rate. The drug "activates the brown fat cells to burn calories and generate heat," said study researcher Dr. Aaron Cypess. He is section head of translational physiology at the U.S. National Institute of Diabetes and Digestive and Kidney Diseases. When the activity of the drug peaked, "the metabolic rate went up by 13 percent on average," Cypess said. That translates ... Read more
Related support groups: Obesity, Overactive Bladder, Myrbetriq, Mirabegron
Full Bladder May Get a Third of Women Over 40 Up at Night
Posted 9 Dec 2014 by Drugs.com
TUESDAY, Dec. 9, 2014 – Many women have to get up more than once a night because of a full bladder, a new study finds. Researchers found that of over 2,000 women aged 40 and up, one-third said they routinely got up at least twice a night to use the bathroom. Doctors refer to that as nocturia, and it can be a sign that you're drinking too much tea or coffee at night – or a signal of a serious health condition. "Traditionally, nocturia has been considered a part of other urinary tract disorders," said lead researcher Dr. Amy Hsu, a fellow at the San Francisco VA Medical Center. But in this study, 40 percent of the women with nocturia reported no other urinary tract symptoms, such as daytime overactive bladder or urine leakage. That suggests nocturia often cannot be attributed to those conditions, according to Hsu, who reports the findings in the January issue of Obstetrics & Gynecology. ... Read more
Related support groups: Overactive Bladder
Bathroom Visits May Add to Sleep Problems for Seniors
Posted 14 Mar 2013 by Drugs.com
THURSDAY, March 14 – Having to get up at night to urinate may worsen the already poor sleep of older people with insomnia, a new study suggests. Treatment of this problem, called nocturia, might help improve the sleep quality among these seniors, the researchers said. The study included older men and women with insomnia. Their patterns of sleeping and waking up to urinate during the night were evaluated for two weeks. The investigators found that 54 percent of all nighttime awakenings were associated with having to urinate. The more often a person had to go to the bathroom during the night, the poorer their self-reported quality of sleep, according to the study, which was published online March 15 in the Journal of Clinical Sleep Medicine. In addition, the study authors noted that nighttime awakenings were 11.5 percent longer on nights when people had to go to the bathroom. Waking up ... Read more
Related support groups: Sleep Disorders, Overactive Bladder
FDA Approves Over-the-Counter Oxytrol for Women to treat Overactive Bladder
Posted 25 Jan 2013 by Drugs.com
January, 25, 2013 – The U.S. Food and Drug Administration today approved Oxytrol for Women, the first over-the-counter treatment for overactive bladder in women ages 18 years and older. Oxytrol will remain available for men with overactive bladder by prescription only. Overactive bladder is a condition in which the bladder squeezes too often or squeezes without warning. Symptoms include leaking urine (urinary incontinence), feeling the sudden and urgent need to urinate, and frequent urination. Overactive bladder affects an estimated 33 million Americans, the majority of whom are older women. Oxytrol for Women contains oxybutynin, a medicine that helps relax the bladder muscle. Oxybutynin belongs to a class of drugs known as anticholinergics. It is the first drug in this class to be made available over-the-counter for treatment of overactive bladder. Oxytrol for Women is a patch ... Read more
Related support groups: Overactive Bladder, Oxybutynin, Oxytrol
First OTC Drug Approved for Women With Overactive Bladder
Posted 25 Jan 2013 by Drugs.com
FRIDAY, Jan. 25 – The drug Oxytrol has been approved by the U.S. Food and Drug Administration as the first over-the-counter treatment for women 18 and older with overactive bladder. Overactive bladder is characterized by symptoms including leakage, frequent urination and feeling the sudden and urgent need to urinate. The condition affects some 33 million Americans, mostly older women. Oxytrol contains oxybutynin, among a class of drugs called anticholinergics that are designed to relax the bladder muscle. Oxytrol is a patch applied to the skin every four days, the FDA said in a news release. The drug will remain available for adult men by prescription only, the agency said. Side effects reported during clinical testing included skin irritation at the patch site, dry mouth and constipation. Oxytrol for Women is marketed by Merck, based in Whitehouse Station, N.J. More information To ... Read more
Related support groups: Overactive Bladder, Oxybutynin, Ditropan, Oxytrol, Gelnique, Ditropan XL, Urotrol, Anturol
Botox Approved for Overactive Bladder
Posted 22 Jan 2013 by Drugs.com
TUESDAY, Jan. 22 – U.S. Food and Drug Administration approval of Botox (onabotulinumtoxinA) has been expanded to include adults with overactive bladder who don't respond to a class of drugs called anticholinergics. Overactive bladder's typical symptoms including leakage, frequent urination and feeling the sudden and urgent need to urinate. Botox, when injected into the bladder, causes it to relax and increases its capacity, the FDA said in a news release. In a clinical study, people treated with Botox after 12 weeks had urinary incontinence 1.6 to 1.9 times less per day than people treated with a placebo, the FDA said. The most common adverse reactions recorded during the study included urinary tract infection, painful urination and incomplete bladder emptying (urinary retention). People who develop urinary retention may have to use a catheter until the situation resolves, the agency ... Read more
Related support groups: Overactive Bladder, Botox, Botox Cosmetic, Onabotulinumtoxina
FDA Gives Nod to Botox to Treat Overactive Bladder
Posted 21 Jan 2013 by Drugs.com
FRIDAY, Jan. 18 – The U.S. Food and Drug Administration on Friday gave its approval for the use of Botox against a form of urinary incontinence known as overactive bladder. "Clinical studies have demonstrated Botox's ability to significantly reduce the frequency of urinary incontinence," Dr. Hylton Joffe, director of the Division of Reproductive and Urologic Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release. "Today's approval provides an important additional treatment option for patients with overactive bladder, a condition that affects an estimated 33 million men and women in the United States," he added. Overactive bladder is a condition where the bladder contracts too frequently or without warning, causing incontinence, sudden/urgent urge to urinate and frequent urination. However, injections of Botox (onabotulinumtoxinA) into the bladder ... Read more
Related support groups: Overactive Bladder, Botox, Botox Cosmetic, Onabotulinumtoxina
FDA Approves Botox to Treat Overactive Bladder
Posted 18 Jan 2013 by Drugs.com
January 18, 2013 – The U.S. Food and Drug Administration today expanded the approved use of Botox (onabotulinumtoxinA) to treat adults with overactive bladder who cannot use or do not adequately respond to a class of medications known as anticholinergics. Overactive bladder is a condition in which the bladder squeezes too often or squeezes without warning. Symptoms include leaking urine (urinary incontinence), feeling the sudden and urgent need to urinate, and frequent urination. When Botox is injected into the bladder muscle, it causes the bladder to relax, increasing the bladder’s storage capacity and reducing episodes of urinary incontinence. Injecting the bladder with Botox is performed using cystoscopy, a procedure that allows a doctor to visualize the interior of the bladder while Botox is being injected. “Clinical studies have demonstrated Botox’s ability to significantly redu ... Read more
Related support groups: Overactive Bladder, Botox, Onabotulinumtoxina
Botox Injections: Option for Urge Incontinence?
Posted 4 Oct 2012 by Drugs.com
THURSDAY, Oct. 4 – Botulinum toxin, the anti-wrinkle treatment known as Botox, can also help women with urge incontinence reduce their leaking episodes, according to a new study. Injecting Botox into the bladder worked as well as daily solifenacin pills, a commonly prescribed treatment for incontinence, the researchers found. The Botox treatment is already approved by the U.S. Food and Drug Administration for urge incontinence due to known neurological injuries such as spinal cord trauma, said lead study Dr. Anthony Visco, chief of urogynecology and reconstructive pelvic surgery at Duke University Medical Center in Durham, N.C. It is not yet approved for incontinence without a recognized cause, known as idiopathic incontinence. Visco and his colleagues conducted what they believe is the first head-to-head comparison of medication and the botulinum toxin. They will present their results ... Read more
Related support groups: Overactive Bladder, Urinary Incontinence, Botox, Onabotulinumtoxina, Botox Cosmetic
FDA Approves Myrbetriq for Overactive Bladder
Posted 28 Jun 2012 by Drugs.com
June 28, 2012 - The U.S. Food and Drug Administration today approved Myrbetriq (mirabegron) to treat adults with overactive bladder, a condition in which the bladder muscle cannot be controlled, squeezes too often or squeezes without warning. An extended-release tablet taken once daily, Myrbetriq improves the storage capacity of the bladder by relaxing the bladder muscle during filling. Symptoms of overactive bladder include the need to urinate too often (urinary frequency), the need to urinate immediately (urinary urgency), and the involuntary leakage of urine as a result of the need to urinate immediately (urge urinary incontinence). “An estimated 33 million Americans suffer from overactive bladder, which is uncomfortable, disrupting and potentially serious,” said Victoria Kusiak, M.D., deputy director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and R ... Read more
Related support groups: Overactive Bladder
Myrbetriq Approved for Overactive Bladder
Posted 28 Jun 2012 by Drugs.com
THURSDAY, June 28 – Myrbetriq (mirabegron) has been approved to treat adults with overactive bladder, a condition affecting some 33 million Americans, the U.S. Food and Drug Administration said Thursday in a news release. The drug is designed to relax the bladder muscle as the bladder fills, minimizing the potential symptoms of needing to urinate too often, needing to urinate immediately or the involuntary leakage of urine, the agency said. The drug's safety and effectiveness were evaluated in clinical studies involving 4,116 people with overactive bladder. The most common side effects were a rise in blood pressure, cold-like symptoms, urinary tract infection, constipation, fatigue, increased heart rate and abdominal pain. Myrbetriq is marketed by Astellas Pharma US, based in Northbrook, Ill. More information The U.S. National Library of Medicine has more about overactive bladder. Read more
Related support groups: Overactive Bladder
Urinary Incontinence Drugs May Be More Trouble Than They're Worth
Posted 9 Apr 2012 by Drugs.com
MONDAY, April 9 – For women with urinary incontinence, the available treatments may cause more problems than they solve and many stop taking the medications because of side effects that can include dry mouth and constipation, a new analysis indicates. Urge incontinence is marked by frequent, sudden urges to urinate that can result in leakage and accidents. Standard treatment includes lifestyle changes, pelvic floor exercises, bladder training and/or medication. There are several types of medications that may be used alone or together for the condition. Generally, these medications relax bladder contractions and help improve bladder function. Researchers from the University of Minnesota School of Public Health analyzed data from 94 studies to see how well the available drugs worked. A given medication was deemed effective if women achieved a 50 percent or more reduction in daily ... Read more
Related support groups: Overactive Bladder, Urinary Incontinence, Oxybutynin, VESIcare, Toviaz, Ditropan, Detrol, Oxytrol, Detrol LA, Gelnique, Solifenacin, Tolterodine, Ditropan XL, Urotrol, Anturol, Fesoterodine
Antares' Oxybutynin Gel Product Approved by FDA for the Treatment of Overactive Bladder
Posted 8 Dec 2011 by Drugs.com
PARSIPPANY, N.J. and EWING, N.J., Dec. 8, 2011 /PRNewswire/ – Watson Pharmaceuticals, Inc. and Antares Pharma, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Antares' topical oxybutynin gel 3% product for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency. OAB is a condition that affects more than 33 million Americans, and the market currently exceeds $2.0 billion annually. Antares' oxybutynin product is a clear, odorless topical gel available in a convenient, metered-dose pump that has demonstrated to be an effective and safe treatment for overactive bladder (OAB). Because the active ingredient is delivered transdermally, it is not metabolized by the liver in the same way as orally administered oxybutynin. This results in a low level of side effects, such as dry mouth and constipation. ... Read more
Related support groups: Overactive Bladder, Oxybutynin
Gelnique Approved for Overactive Bladder
Posted 28 Jan 2009 by Drugs.com
WEDNESDAY, Jan. 28 – The U.S. Food and Drug Administration has approved Watson Pharmaceuticals' Gelnique (oxybutynin chloride) to treat symptoms of overactive bladder, the company said in a news release. Gelnique is a topical gel that's applied daily to the thigh, abdomen, upper arm or shoulder. Since it's absorbed through the skin, it's not metabolized by the liver as it would be were the drug's active ingredient, oxybutynin, taken orally, Watson said. The most frequent side effects reported during clinical testing included dry mouth and reactions where the gel was applied. Overactive bladder, with symptoms including incontinence, urgency and waking up at night to urinate, affects as many as 33 million adults in the United States, the company said. More information The U.S. National Institute on Aging has more on urinary incontinence. Read more
Related support groups: Overactive Bladder
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