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Osteoporosis Blog

Related terms: Bone Thinning

Steroid Injections for Back Pain May Lower Bone Mass

Posted 2 Dec 2012 by

SATURDAY, Dec. 1 – Older women who get steroid injections in the spine to treat lower back pain may be at risk for bone loss in their hips, a small study suggests. It is well known that the anti-inflammatory steroid medications used to treat diseases such as asthma and rheumatoid arthritis may decrease a person's bone mass over time. But it hasn't been clear whether steroid shots – one treatment option for lower back pain – are connected to bone loss. "It's been thought that [the steroids] might stay in the epidural space of the spine," explained study author Dr. Shlomo Mandel, an orthopedic physician at Henry Ford West Bloomfield Hospital, in Michigan. Safety questions about steroid injections also have been raised in recent months, as U.S. health officials investigate a deadly outbreak of fungal meningitis linked to steroid shots produced by a Massachusetts compounding pharmacy ... Read more

Related support groups: Back Pain, Prednisone, Osteoporosis, Methylprednisolone, Prednisolone, Cortisone, Hydrocortisone, Medrol, Triamcinolone, Dexamethasone, Betamethasone, Decadron, Budesonide, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Orapred, Depo-Medrol

Deep Belly Fat Could Weaken Men's Bones, Study Suggests

Posted 28 Nov 2012 by

WEDNESDAY, Nov. 28 – Obese men with a lot of deep belly fat are at greater risk for bone-thinning than other men, a new study finds. Although bone loss, or osteoporosis, is widely believed to be a health issue affecting women, researchers found that "visceral fat," which is located deep under the muscles in the abdomen, is linked to bone loss and decreased bone strength in men. "Most studies on osteoporosis have focused on women. Men were thought to be relatively protected against bone loss, especially obese men," Dr. Miriam Bredella, a radiologist at Massachusetts General Hospital and associate professor of radiology at Harvard Medical School in Boston, said in a news release from the Radiological Society of North America. "It is important for men to be aware that excess belly fat is not only a risk factor for heart disease and diabetes, it is also a risk factor for bone loss," ... Read more

Related support groups: Obesity, Osteoporosis

Men May Benefit From Osteoporosis Drug, Too: Study

Posted 31 Oct 2012 by

WEDNESDAY, Oct. 31 – Older men at risk for fractures from osteoporosis may reap the same benefit as women from bone-strengthening drugs called bisphosphonates, a new study suggests. In this case, one such drug called zoledronic acid (Reclast) significantly reduced backbone breaks in men suffering from osteoporosis. Bisphosphonates work by building bone mass, the researchers explained. Age-linked fracture risk doesn't disappear "just because you're a man," said Dr. Robert Recker, president of the National Osteoporosis Foundation, who had no part in the study. "We have ignored the problem in men," he believes. "Half of women over 40 will have an osteoporotic fracture before they die and about 25 percent of men will, too, so it's a substantial problem." However, there are ways to reduce the risk in men, just as there are in women, Recker said. "This study documents this for one of the ... Read more

Related support groups: Osteoporosis, Vitamin D Deficiency, Reclast, Fracture, bone, Zometa, Aclasta, Zoledronic Acid, Vitamin D Insufficiency, Prevention of Fractures

Ladies, Drink to Your (Bone) Health

Posted 11 Jul 2012 by

WEDNESDAY, July 11 – Drinking one or two alcoholic beverages several times a week may improve the bone health of older women and reduce their risk for osteoporosis, a small study suggests. Bones are living tissue with old bone continually removed and replaced in a process called remodeling. In people with the bone-thinning disease osteoporosis, more bone is lost than replaced. Postmenopausal women are at particular risk because of reduced estrogen, a hormone essential for bone strength, the researchers explained. "This study clearly demonstrates that even small amounts of alcohol have potent actions and can rapidly impact bone metabolism," said lead researcher Urszula Iwaniec, an associate professor in the College of Public Health and Human Sciences at Oregon State University. As part of a healthy lifestyle, "moderate alcohol may slow bone loss by lowering bone turnover," she said. ... Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis

Muscle Mass Linked to Bone Health in Some Parts of Body

Posted 28 Jun 2012 by

THURSDAY, June 28 – The health of muscles and bones are interlinked in certain areas of the body, and there are distinct differences between women and men, a new study says. The findings could be used to improve identification of people at increased risk for falls and fractures as they age, according to the Mayo Clinic researchers. They analyzed data from 272 women and 317 men, ages 20 to 97, taking part in a Mayo Clinic bone health study and found that muscle mass is associated with bone strength at particular locations in the body. In women, muscle mass is strongly connected to the health of bones in load-bearing areas such as the hip, lower spine and shinbone. Muscle mass is also associated with bone health in women's forearms, a non-load-bearing site that's at increased risk of fracture following menopause. The researchers also found that higher circulating levels of a protein ... Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis, Fracture, bone, Prevention of Fractures

Older Women Should Not Take Calcium, Vitamin D: Task Force

Posted 12 Jun 2012 by

TUESDAY, June 12 – A leading U.S. government advisory panel has proposed that postmenopausal women not take low-dose calcium and vitamin D supplements daily to ward off bone fractures. But the jury is still out on higher doses of these supplements, stated the U.S. Preventive Services Task Force (USPSTF), which issued the draft recommendations Tuesday. Public comment on the draft recommendations is invited until July 10. The news was a bit of a bombshell, given that women have been told for so long to take calcium and vitamin D, said Dr. Suzanne Steinbaum, director of women and heart disease at Lenox Hill Hospital in New York City and a spokeswoman for the American Heart Association. "What we're really seeing is no role for calcium for the prevention of osteoporotic fractures. At this point, there's no reason to be taking calcium," she noted. But, the issue of which women should take ... Read more

Related support groups: Osteoporosis, Vitamin D, Tums, Vitamin D3, Prevention of Osteoporosis, Caltrate, Calcium Carbonate, Calcium Citrate, Cholecalciferol, Ergocalciferol, Citracal, Drisdol, Oyster, Oyster Shell, Titralac, Os-Cal, Os-Cal 500, Calciferol, Oysco 500, Calcid

Two-Thirds of Osteo Hip Fractures Occur After 80: U.S. Study

Posted 8 Jun 2012 by

THURSDAY, June 7 – Patients aged 80 and older account for nearly two-thirds of osteoporosis-related hip fractures in the United States, a new study finds. The researchers said their results show the need for more aggressive prevention, diagnosis and treatment of osteoporosis in this age group, referred to as the extreme elderly. The study authors analyzed U.S. national daton 4.3 million patients who suffered osteoporotic hip fractures between 1993 and 2008, and found that 67 percent of those hip fractures occurred in the extreme elderly. During that time, the number of osteoporotic hip fractures among the extreme elderly increased from about 172,000 to 180,000, even though hip fracture prevalence declined from 2,236 to 1,600 per 1,000 person-years over the same period. The researchers noted that the extreme elderly population in the United States rose from 7.7 million in 1993 to 11.2 ... Read more

Related support groups: Osteoporosis, Fracture, bone

Calcium Supplements May Be Bad for Your Heart: Study

Posted 23 May 2012 by

WEDNESDAY, May 23 – Many older Americans take calcium supplements to prevent bone loss, but they may be significantly increasing their risk for a heart attack, a new study suggests. These supplements do not help prevent heart attacks or stroke as some previous research has suggested, the study authors say. But dietary calcium might reduce the risk, they noted. "While a moderately high intake of calcium from diet may go along with a lower risk of heart attack, this is not true for supplementary calcium intake," said lead researcher Sabine Rohrmann, from the division of cancer epidemiology and prevention at the Institute of Social and Preventive Medicine at the University of Zurich in Switzerland. "Instead of taking calcium supplements, men and women who want to increase their calcium intake should rely on foods, such as low-fat dairy products or mineral water, [that are] rich in ... Read more

Related support groups: Osteoporosis, Dietary Supplementation, Tums, Prevention of Osteoporosis, Caltrate, Calcium Carbonate, Calcium Citrate, Citracal, Oyster, Oyster Shell, Titralac, Calcium Gluconate, Os-Cal 500, Os-Cal, Chooz, Oysco 500, Calcid, Maalox Regular Strength, Rolaids Soft Chew, Tums Kids

More Research Points to Long-Term Ills With Bone Drugs

Posted 21 May 2012 by

MONDAY, May 21 – Adding more weight to concerns about possible long-term dangers of osteoporosis drugs, a new study finds that people who take the drugs, known as bisphosphonates, may be at increased risk for atypical fractures of the thigh bone (femur). Osteoporosis is a bone-thinning disease that is common in older women. An atypical femoral fracture is an unusual type of break that often occurs spontaneously, without any major leg injury. In the new study, Swiss researchers looked at 477 patients, aged 50 and older, who were hospitalized with a femoral fracture. Of those patients, 39 had atypical fractures and 438 had a classic fracture (a more common fracture with a typical pattern). These groups were compared with 200 people without femoral fractures. The findings were published online May 21 in the journal Archives of Internal Medicine. The investigators found that 82 percent of ... Read more

Related support groups: Osteoporosis, Fosamax, Boniva, Alendronate, Reclast, Actonel, Prevention of Osteoporosis, Fracture, bone, Zometa, Aclasta, Ibandronate, Atelvia, Zoledronic Acid, Risedronate, Pamidronate, Aredia, Skelid, Etidronate, Fosamax Plus D, Actonel with Calcium

Certain Genetic Regions May Be Tied to Osteoporosis

Posted 15 Apr 2012 by

SUNDAY, April 15 – A large international group of researchers has identified 32 new genetic regions linked to fractures and osteoporosis. Variations in these regions could offer protection from, or greater risk for, bone-weakening disease, the investigators reported in a new study published in the April 15 online edition of Nature Genetics. The study authors added that their findings could lead to the development of new osteoporosis drugs. "We're learning that the genetic architecture of disease is very complex," one of the study's authors and the methodological leader of the consortium, Dr. John Ioannidis, chief of the Stanford Prevention Research Center, said in a university news release. The research, which involved 17 studies that compared common genetic variants in more than 100,000 people, pinpointed six regions linked to risk of fractures of the femur (thigh bone) or lower back. ... Read more

Related support groups: Osteoporosis

Osteoporosis Drugs May Lead to Eye Trouble: Study

Posted 2 Apr 2012 by

MONDAY, April 2 – First-time users of osteoporosis drugs called oral bisphosphonates may be at increased risk for serious inflammatory eye disease, a new study contends. Oral bisphosphonates, such as Fosamax and Actonel, are the most commonly prescribed class of drugs to prevent or slow osteoporosis, a disease that causes very weak bones. Previous studies have linked the drugs to problems such as unusual fractures, irregular heartbeat and esophageal and colon cancer. In addition, some case reports have shown an association between the drugs and inflammatory eye diseases – anterior uveitis and scleritis – that can cause serious vision impairment. In this new study, Canadian researchers compared nearly 11,000 first-time users of oral bisphosphonates and more than 920,000 non-users. First-time users had incidence rates of 29 per 10,000 person-years for uveitis and 63 per 10,000 ... Read more

Related support groups: Osteoporosis, Fosamax, Boniva, Alendronate, Reclast, Actonel, Prevention of Osteoporosis, Zometa, Aclasta, Ibandronate, Zoledronic Acid, Atelvia, Risedronate, Pamidronate, Aredia, Etidronate, Skelid, Fosamax Plus D, Actonel with Calcium, Didronel IV

Generic Boniva Approved for Osteoporosis

Posted 19 Mar 2012 by

MONDAY, March 19 – The first generic versions of the once-monthly osteoporosis drug Boniva (ibandronate) have been approved by the U.S. Food and Drug Administration. Osteoporosis, characterized by a thinning of the bones, is the most common type of bone disease, the agency said in a news release Monday. More common in postmenopausal women, it increases the risk of fracture, especially of the hip, spine and wrist. More than 40 million people in the United States have the disease or are at significant risk for it, the FDA said. Approvals to produce generic Boniva have been granted to: Apotex Inc., Orchid Healthcare and Mylan Pharmaceuticals. Generic drugs are medically equivalent to the brand-name versions and are subject to the same quality standards, the agency said. Generic Boniva will be accompanied by a guide that explains potential serious reactions, including esophagus problems; ... Read more

Related support groups: Osteoporosis, Boniva, Prevention of Osteoporosis, Ibandronate, Bondronat

FDA Approves Binosto, First and Only Effervescent Osteoporosis Treatment in a Buffered Solution

Posted 15 Mar 2012 by

FREIENBACH, Switzerland, March 14, 2012 /PRNewswire/ – EffRx Pharmaceuticals SA today announced that the U.S. Food and Drug Administration (FDA) has approved Binosto (alendronate sodium) Effervescent Tablets, previously known as EX101, for the treatment of osteoporosis in postmenopausal women, and as a treatment to increase bone mass in men with osteoporosis. EffRx anticipates that Binosto will be commercially available in the United States in the third quarter of 2012. Christer Rosen, Chairman & CEO of EffRx states: "We are very pleased to receive this approval from the FDA. Binosto is a breakthrough innovation for the treatment of osteoporosis, offering those patients who have difficulty with tablets the proven fracture risk reduction of alendronate in a pleasant tasting and easy-to-swallow buffered solution." Osteoporosis affects more than 200 million people in the 7 major markets ... Read more

Related support groups: Osteoporosis, Alendronate

Implanted Microchip Might Be Future of Drug Delivery

Posted 16 Feb 2012 by

THURSDAY, Feb. 16 – Remote controls may not be for just appliances anymore. In a new small study, women with severe osteoporosis were implanted with a microchip that releases bone-building drugs at the push of a button, a delivery method that could someday become common for various health conditions. Roughly 1.5-by-2.5 inches in size, the microchip significantly improved patient compliance with a drug regimen that normally requires painful daily self-injections, study authors said. The clinical trial, conducted on seven osteoporosis patients in Denmark, was the first to test a wirelessly controlled microchip in this capacity. "It frees patients from the burden of managing their disease on a daily basis," said Robert Farra, co-author of the study and president and chief operating officer of MicroCHIPS Inc., the Waltham, Mass., company that funded and supervised the trial. "I think there ... Read more

Related support groups: Osteoporosis, Forteo, Teriparatide

Heart Failure, Osteoporosis Go 'Hand-in-Hand': Researchers

Posted 7 Feb 2012 by

TUESDAY, Feb. 7 – Heart failure is linked to thinning of the bones and an increased risk of fractures, a new study indicates. The findings suggest that aggressive screening for osteoporosis may be important for heart failure patients, the researchers said. They looked at data from about 45,500 adults who underwent bone mineral density testing for the first time and were followed for up to 10 years. Of those people, 1,841 had recent-onset heart failure. After the researchers adjusted for traditional osteoporosis risk factors, they concluded that heart failure was associated with a 30 percent increased risk of major fractures. The study will be published in the April issue of the Journal of Clinical Endocrinology & Metabolism. "Our study demonstrates for the first time that heart failure and thinning of bones go hand in hand," study author Dr. Sumit Majumdar, of the University of Alberta ... Read more

Related support groups: Osteoporosis, Heart Failure, Congestive Heart Failure, Fracture, bone

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