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Osteoporosis Blog

Related terms: Bone Thinning

Combo Drug Therapy May Work Best to Strengthen Bones: Study

Posted 14 May 2013 by Drugs.com

TUESDAY, May 14 – A new combination drug therapy for osteoporosis appears to increase bone density more effectively than any treatment now on the market, according to the results of a small clinical trial. Researchers found that postmenopausal women experienced significant amounts of bone growth by taking a bone-building drug called teriparatide with denosumab, a targeted therapy drug used to stop bone loss. "A combination of these two medications increased bone density more than either does on its own, and it is more effective than any currently approved therapy," said study author Dr. Benjamin Leder, who is with the endocrine unit at Massachusetts General Hospital in Boston. The 12-month study, published online May 15 in The Lancet, was funded in part by the drugs' makers, Eli Lilly and Amgen. It involved 94 postmenopausal women being treated for osteoporosis, a bone-thinning ... Read more

Related support groups: Osteoporosis, Forteo, Prolia, Xgeva, Denosumab, Teriparatide

Gene Discoveries Give Hope Against 'Brittle Bone' Disease

Posted 8 May 2013 by Drugs.com

WEDNESDAY, May 8 – Mutations in a gene involved in bone development appear to cause certain severe forms of bone loss, a finding that could lead to new therapies for the common bone-thinning disorder osteoporosis, researchers report. The mutations were found in a Swedish family with 10 members affected by a severe, early onset form of osteoporosis, as well as a Hmong family from Laos in which two sisters suffered from osteogenesis imperfecta. Osteogenesis imperfecta, which is also known as brittle bone disease, affects six to seven out of every 100,000 people worldwide. The disease causes the bones to break easily, often from little or no trauma. There are four main forms, the most severe of which is fatal before or soon after birth. The most common – and mildest – form is Type 1, in which most of a child's bone fractures happen before puberty. Some other problems, such as weak ... Read more

Related support groups: Osteoporosis

Healthy Older Women Advised Against Taking Calcium

Posted 25 Feb 2013 by Drugs.com

MONDAY, Feb. 25 – Healthy older women should not take calcium and vitamin D supplements to prevent fractures, according to a final recommendation issued Monday by the U.S. Preventive Services Task Force. In healthy adults, lower doses of calcium and vitamin D seem to be ineffective. As for higher doses, it's still up in the air, the government group said. The new recommendations do not apply to people who are known to be vitamin D-deficient or who already have osteoporosis, the U.S. Preventive Services Task Force (USPSTF) noted. Every year about 1.5 million fractures in the United States are attributed to osteoporosis, which is caused by a decrease in bone mass and density that makes bones fragile and more susceptible to a break. Almost half of all women older than 50 will have an osteoporosis-related fracture in their lifetime, according to the USPSTF. Calcium is one of the main ... Read more

Related support groups: Osteoporosis, Tums, Prevention of Osteoporosis, Caltrate, Calcium Citrate, Calcium Carbonate, Pepcid Complete, Citracal, Arthritis Pain Formula, Rolaids, Titralac, Oyster, Oyster Shell, Calcium Chloride, Calcium Gluconate, Slow-Mag, Os-Cal 500, Os-Cal, Titralac Plus, Ascriptin

Health Tip: You May Need a Bone Density Test

Posted 4 Jan 2013 by Drugs.com

-- A bone density test measures the amounts of calcium and other minerals in your bones, and how likely you are to develop thin and brittle bones – characteristics of a condition called osteoporosis. The womenshealth.gov website says your doctor should evaluate the following factors before recommending a bone density test: Your age, and whether you have become menopausal. How tall you are and how much you weigh. Whether you are a smoker and drink alcohol. Your family history of a broken hip, particularly among your parents. Medications you take. Whether you have a disorder that increases your risk of osteoporosis. Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis, Osteopenia

Teen Girls Who Smoke May Up Risk for Future Bone Disease

Posted 4 Dec 2012 by Drugs.com

TUESDAY, Dec. 4 – Teen girls who smoke may be at greater risk for osteoporosis, according to a new study that found girls who smoke build up less bone during this critical growth period in their lives. In osteoporosis, bones lose mineral density and become brittle. People with the condition – which is much more common in women than men – are susceptible to fractures. "As much bone is accrued in the two years surrounding a girl's first menstrual cycle as is lost in the last four decades of life," said principal investigator, Lorah Dorn, director of research in the division of adolescent medicine at Cincinnati Children's Hospital Medical Center, in a center news release. The researchers examined how smoking, depression, anxiety and alcohol affected the buildup of bone among 262 girls ranging in age from 11 to 19 years old. Over the course of three years, the girls underwent clinical ... Read more

Related support groups: Smoking, Osteoporosis

Steroid Injections for Back Pain May Lower Bone Mass

Posted 2 Dec 2012 by Drugs.com

SATURDAY, Dec. 1 – Older women who get steroid injections in the spine to treat lower back pain may be at risk for bone loss in their hips, a small study suggests. It is well known that the anti-inflammatory steroid medications used to treat diseases such as asthma and rheumatoid arthritis may decrease a person's bone mass over time. But it hasn't been clear whether steroid shots – one treatment option for lower back pain – are connected to bone loss. "It's been thought that [the steroids] might stay in the epidural space of the spine," explained study author Dr. Shlomo Mandel, an orthopedic physician at Henry Ford West Bloomfield Hospital, in Michigan. Safety questions about steroid injections also have been raised in recent months, as U.S. health officials investigate a deadly outbreak of fungal meningitis linked to steroid shots produced by a Massachusetts compounding pharmacy ... Read more

Related support groups: Back Pain, Prednisone, Osteoporosis, Methylprednisolone, Prednisolone, Cortisone, Medrol, Hydrocortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Cortef, Celestone, Entocort EC, Depo-Medrol, Orapred

Deep Belly Fat Could Weaken Men's Bones, Study Suggests

Posted 28 Nov 2012 by Drugs.com

WEDNESDAY, Nov. 28 – Obese men with a lot of deep belly fat are at greater risk for bone-thinning than other men, a new study finds. Although bone loss, or osteoporosis, is widely believed to be a health issue affecting women, researchers found that "visceral fat," which is located deep under the muscles in the abdomen, is linked to bone loss and decreased bone strength in men. "Most studies on osteoporosis have focused on women. Men were thought to be relatively protected against bone loss, especially obese men," Dr. Miriam Bredella, a radiologist at Massachusetts General Hospital and associate professor of radiology at Harvard Medical School in Boston, said in a news release from the Radiological Society of North America. "It is important for men to be aware that excess belly fat is not only a risk factor for heart disease and diabetes, it is also a risk factor for bone loss," ... Read more

Related support groups: Obesity, Osteoporosis

Men May Benefit From Osteoporosis Drug, Too: Study

Posted 31 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 31 – Older men at risk for fractures from osteoporosis may reap the same benefit as women from bone-strengthening drugs called bisphosphonates, a new study suggests. In this case, one such drug called zoledronic acid (Reclast) significantly reduced backbone breaks in men suffering from osteoporosis. Bisphosphonates work by building bone mass, the researchers explained. Age-linked fracture risk doesn't disappear "just because you're a man," said Dr. Robert Recker, president of the National Osteoporosis Foundation, who had no part in the study. "We have ignored the problem in men," he believes. "Half of women over 40 will have an osteoporotic fracture before they die and about 25 percent of men will, too, so it's a substantial problem." However, there are ways to reduce the risk in men, just as there are in women, Recker said. "This study documents this for one of the ... Read more

Related support groups: Osteoporosis, Vitamin D Deficiency, Reclast, Fracture, bone, Zometa, Aclasta, Zoledronic Acid, Vitamin D Insufficiency, Prevention of Fractures

Ladies, Drink to Your (Bone) Health

Posted 11 Jul 2012 by Drugs.com

WEDNESDAY, July 11 – Drinking one or two alcoholic beverages several times a week may improve the bone health of older women and reduce their risk for osteoporosis, a small study suggests. Bones are living tissue with old bone continually removed and replaced in a process called remodeling. In people with the bone-thinning disease osteoporosis, more bone is lost than replaced. Postmenopausal women are at particular risk because of reduced estrogen, a hormone essential for bone strength, the researchers explained. "This study clearly demonstrates that even small amounts of alcohol have potent actions and can rapidly impact bone metabolism," said lead researcher Urszula Iwaniec, an associate professor in the College of Public Health and Human Sciences at Oregon State University. As part of a healthy lifestyle, "moderate alcohol may slow bone loss by lowering bone turnover," she said. ... Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis

Muscle Mass Linked to Bone Health in Some Parts of Body

Posted 28 Jun 2012 by Drugs.com

THURSDAY, June 28 – The health of muscles and bones are interlinked in certain areas of the body, and there are distinct differences between women and men, a new study says. The findings could be used to improve identification of people at increased risk for falls and fractures as they age, according to the Mayo Clinic researchers. They analyzed data from 272 women and 317 men, ages 20 to 97, taking part in a Mayo Clinic bone health study and found that muscle mass is associated with bone strength at particular locations in the body. In women, muscle mass is strongly connected to the health of bones in load-bearing areas such as the hip, lower spine and shinbone. Muscle mass is also associated with bone health in women's forearms, a non-load-bearing site that's at increased risk of fracture following menopause. The researchers also found that higher circulating levels of a protein ... Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis, Fracture, bone, Prevention of Fractures

Older Women Should Not Take Calcium, Vitamin D: Task Force

Posted 12 Jun 2012 by Drugs.com

TUESDAY, June 12 – A leading U.S. government advisory panel has proposed that postmenopausal women not take low-dose calcium and vitamin D supplements daily to ward off bone fractures. But the jury is still out on higher doses of these supplements, stated the U.S. Preventive Services Task Force (USPSTF), which issued the draft recommendations Tuesday. Public comment on the draft recommendations is invited until July 10. The news was a bit of a bombshell, given that women have been told for so long to take calcium and vitamin D, said Dr. Suzanne Steinbaum, director of women and heart disease at Lenox Hill Hospital in New York City and a spokeswoman for the American Heart Association. "What we're really seeing is no role for calcium for the prevention of osteoporotic fractures. At this point, there's no reason to be taking calcium," she noted. But, the issue of which women should take ... Read more

Related support groups: Osteoporosis, Vitamin D, Tums, Prevention of Osteoporosis, Vitamin D3, Caltrate, Calcium Citrate, Calcium Carbonate, Cholecalciferol, Citracal, Ergocalciferol, Drisdol, Oyster, Oyster Shell, Titralac, Os-Cal, Os-Cal 500, Tums E-X, Calciferol, Oysco 500

Two-Thirds of Osteo Hip Fractures Occur After 80: U.S. Study

Posted 8 Jun 2012 by Drugs.com

THURSDAY, June 7 – Patients aged 80 and older account for nearly two-thirds of osteoporosis-related hip fractures in the United States, a new study finds. The researchers said their results show the need for more aggressive prevention, diagnosis and treatment of osteoporosis in this age group, referred to as the extreme elderly. The study authors analyzed U.S. national daton 4.3 million patients who suffered osteoporotic hip fractures between 1993 and 2008, and found that 67 percent of those hip fractures occurred in the extreme elderly. During that time, the number of osteoporotic hip fractures among the extreme elderly increased from about 172,000 to 180,000, even though hip fracture prevalence declined from 2,236 to 1,600 per 1,000 person-years over the same period. The researchers noted that the extreme elderly population in the United States rose from 7.7 million in 1993 to 11.2 ... Read more

Related support groups: Osteoporosis, Fracture, bone

Calcium Supplements May Be Bad for Your Heart: Study

Posted 23 May 2012 by Drugs.com

WEDNESDAY, May 23 – Many older Americans take calcium supplements to prevent bone loss, but they may be significantly increasing their risk for a heart attack, a new study suggests. These supplements do not help prevent heart attacks or stroke as some previous research has suggested, the study authors say. But dietary calcium might reduce the risk, they noted. "While a moderately high intake of calcium from diet may go along with a lower risk of heart attack, this is not true for supplementary calcium intake," said lead researcher Sabine Rohrmann, from the division of cancer epidemiology and prevention at the Institute of Social and Preventive Medicine at the University of Zurich in Switzerland. "Instead of taking calcium supplements, men and women who want to increase their calcium intake should rely on foods, such as low-fat dairy products or mineral water, [that are] rich in ... Read more

Related support groups: Osteoporosis, Dietary Supplementation, Tums, Prevention of Osteoporosis, Caltrate, Calcium Citrate, Calcium Carbonate, Citracal, Oyster Shell, Titralac, Oyster, Calcium Gluconate, Os-Cal 500, Os-Cal, Oysco 500, Calcid, Chooz, Tums E-X, Amitone, Citracal Liquitab

More Research Points to Long-Term Ills With Bone Drugs

Posted 21 May 2012 by Drugs.com

MONDAY, May 21 – Adding more weight to concerns about possible long-term dangers of osteoporosis drugs, a new study finds that people who take the drugs, known as bisphosphonates, may be at increased risk for atypical fractures of the thigh bone (femur). Osteoporosis is a bone-thinning disease that is common in older women. An atypical femoral fracture is an unusual type of break that often occurs spontaneously, without any major leg injury. In the new study, Swiss researchers looked at 477 patients, aged 50 and older, who were hospitalized with a femoral fracture. Of those patients, 39 had atypical fractures and 438 had a classic fracture (a more common fracture with a typical pattern). These groups were compared with 200 people without femoral fractures. The findings were published online May 21 in the journal Archives of Internal Medicine. The investigators found that 82 percent of ... Read more

Related support groups: Osteoporosis, Fosamax, Boniva, Alendronate, Reclast, Actonel, Fracture, bone, Prevention of Osteoporosis, Zometa, Aclasta, Atelvia, Ibandronate, Zoledronic Acid, Risedronate, Pamidronate, Aredia, Etidronate, Fosamax Plus D, Skelid, Actonel with Calcium

Certain Genetic Regions May Be Tied to Osteoporosis

Posted 15 Apr 2012 by Drugs.com

SUNDAY, April 15 – A large international group of researchers has identified 32 new genetic regions linked to fractures and osteoporosis. Variations in these regions could offer protection from, or greater risk for, bone-weakening disease, the investigators reported in a new study published in the April 15 online edition of Nature Genetics. The study authors added that their findings could lead to the development of new osteoporosis drugs. "We're learning that the genetic architecture of disease is very complex," one of the study's authors and the methodological leader of the consortium, Dr. John Ioannidis, chief of the Stanford Prevention Research Center, said in a university news release. The research, which involved 17 studies that compared common genetic variants in more than 100,000 people, pinpointed six regions linked to risk of fractures of the femur (thigh bone) or lower back. ... Read more

Related support groups: Osteoporosis

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