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Related terms: Fredrickson Type IIb Hyperlipoproteinemia, Hyperlipoproteinemia, Fredrickson Type IIb

Do Cholesterol Drugs Affect Aggression?

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – Cholesterol-lowering statin drugs might influence a person's aggressive behaviors, increasing or decreasing their irritability and violent tendencies, a new clinical trial suggests. Men taking statins typically become less aggressive, while women on statins tend to become more aggressive, according to findings published July 1 in the journal PLOS ONE. "Clinicians should be aware of this, and it's not bad for patients to be aware of it," said lead author Dr. Beatrice Golomb, a principal investigator at the University of California, San Diego School of Medicine. "If an individual develops a behavioral change, in my view medication should always be considered as a possibility." However, the effect appears to be minimal and needs to be verified with follow-up studies, said one outside expert, Robert Geffner, founding president of the Institute on Violence, Abuse & ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, Red Yeast Rice, Livalo, Pravachol, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Lescol XL, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL)

Half of U.S. Hispanics With High Cholesterol Unaware They Have It: Study

Posted 24 Jun 2015 by Drugs.com

WEDNESDAY, June 24, 2015 – Nearly half of Hispanic people in the United States with high cholesterol levels aren't aware they have the health problem and more than two-thirds who are aware aren't being treated, a new study indicates. Reviewing data from more than 16,000 Hispanics between the ages of 18 and 74, the researchers found that about 44 percent of men and 40 percent of women had high cholesterol, greater proportions overall than among the general U.S. population. Almost one-third of all American adults have high levels of low-density lipoprotein (LDL) or "bad" cholesterol, according to the U.S. Centers for Disease Control and Prevention, and less than a third have the condition under control. High cholesterol levels are a major risk factor for developing heart disease or stroke since a build-up of the fatty substance can narrow blood vessels and hinder blood flow to the heart ... Read more

Related support groups: High Cholesterol, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

Health Tip: What's Behind High Cholesterol?

Posted 24 Jun 2015 by Drugs.com

-- High cholesterol is a risk factor for serious health problems, from heart attack to stroke. The National Heart Lung and Blood Institute mentions these possible causes: Eating a diet high in cholesterol-rich foods, such as meat, cheese, egg yolks and other animal products. Foods high in saturated and trans fats also increase cholesterol. Being overweight or lack of physical activity can lead to extra pounds and boost cholesterol. Being age 55 or older increases your risk of high cholesterol. Having an inherited condition called familial cholesterolemia leads to high cholesterol. Read more

Related support groups: Obesity, High Cholesterol, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL)

Can U.S. Health-Care System Afford New, Improved Cholesterol Drugs?

Posted 18 Jun 2015 by Drugs.com

THURSDAY, June 18, 2015 – A new class of powerful cholesterol drugs is poised to hit the market, and doctors are both hopeful about their potential, and worried that insurers won't pay for them. The drugs, known as PCSK9 inhibitors, can drastically cut LDL cholesterol – the "bad" kind linked to increased risks of heart attack and stroke. And they are expected to open up a new option for people who cannot take statins, the drugs that have been the standard for cholesterol-lowering since the 1980s. Last week, an advisory panel to the U.S. Food and Drug Administration recommended the agency approve two PCSK9 inhibitors: alirocumab (Praluent) and evolocumab (Repatha). The FDA, which usually follows the recommendations of its advisory panels, is expected to OK both drugs. Some cardiologists have heralded PCSK9 inhibitors as a breakthrough – particularly for patients who can't take statins ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Zetia, Rosuvastatin, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, Red Yeast Rice, Livalo, Pravachol, High Cholesterol - Familial Homozygous, Ezetimibe, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol

FDA Advisers Weigh 2 New Cholesterol Drugs

Posted 9 Jun 2015 by Drugs.com

TUESDAY, June 9, 2015 – U.S. health experts are weighing whether to endorse two drugs from a new class of cholesterol medications that seem to sharply cut "bad" LDL cholesterol in people who don't fare well on the commonly used drugs called statins. The new drugs are known as PCSK9 inhibitors. U.S. Food and Drug Administration advisers are meeting Tuesday and Wednesday to discuss and possibly recommend approval of the drugs alirocumab (Praluent) and evolocumab (Repatha). While the FDA isn't compelled to follow the recommendations of its advisory committees, it usually does so. A recent review of 24 clinical trials – published April 28 in the Annals of Internal Medicine – found that PCSK9 inhibitors lowered people's LDL cholesterol by about 47 percent, on average. More important, the drugs seemed to cut the risk of heart attack or death from heart disease, according to the ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Lescol XL, Mevacor, Baycol, Pitavastatin

Staying Fit May Delay Onset of High Cholesterol, Study Finds

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – Men who keep fit may find they delay normal age-related increases in blood cholesterol levels by up to 15 years, a new study suggests. It is common for cholesterol levels to rise with age and then decrease later in life, the study authors explained in background notes. Previous studies have shown that high cholesterol levels can be a risk factor for heart disease. Regular physical activity can lower this risk, the researchers said. "Exercise and being fit helps keep arteries clear by lowering 'bad' [LDL] cholesterol and boosting 'good' [HDL] cholesterol," explained study author Dr. Xuemei Sui, an assistant professor at the Arnold School of Public Health at the University of South Carolina in Columbia, S.C. "It also reduces other risk factors for atherosclerosis [narrowed arteries] and blood clots, such as high blood pressure, diabetes, obesity and stress," Sui ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Zetia, Rosuvastatin, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, Red Yeast Rice, Livalo, Pravachol, High Cholesterol - Familial Homozygous, Ezetimibe, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Lescol

New Guidelines Would Greatly Boost Number of Young People on Statins

Posted 6 Apr 2015 by Drugs.com

MONDAY, April 6, 2015 – If all doctors followed new cholesterol guidelines aimed at children, almost half a million Americans aged 17 to 21 would be prescribed a cholesterol-lowering statin drug, a new study predicts. In 2011, the U.S. National Heart, Lung, and Blood Institute (NHLBI) issued new guidelines on reducing heart disease in adolescents and young adults. Those guidelines recommended that all people aged 17 to 21 get their blood levels of cholesterol checked, and statin treatment be initiated if cholesterol was at a certain level. In contrast, the American College of Cardiology (ACC) and American Heart Association (AHA) are sticking by adult-focused guidelines that more tightly restrict the use of statins for those under 40 years age. In the new study, researchers led by Dr. Holly Gooding of Boston Children's Hospital looked at data from more than 6,300 participants, aged 17 ... Read more

Related support groups: High Cholesterol, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

For Cholesterol Control, Experts Urge More Than Meds

Posted 29 Dec 2010 by Drugs.com

TUESDAY, Dec. 28 – Advances in medical science have made it easier than ever to lower dangerous cholesterol levels. A class of cholesterol-lowering drugs known as statins have proven particularly effective, reducing the risk for heart-related death by as much as 40 percent in people who have already suffered a heart attack, said Dr. Vincent Bufalino, president and chief executive of Midwest Heart Specialists and a spokesman for the American Heart Association. "People have said we need them in the drinking water because they are just so effective in lowering cholesterol," Bufalino said. But he and other doctors warn that when it comes to controlling cholesterol and enjoying overall health, nothing beats lifestyle changes, such as a heart-friendly diet and regular exercise. "Once we became a fast-food generation, it's just too easy to order it at the first window, pick it up at the ... Read more

Related support groups: High Cholesterol, Hypertriglyceridemia, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia, Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), Hyperlipoproteinemia Type IV (Elevated VLDL)

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