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HIV Infection Blog

Related terms: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome (AIDS), Acute HIV Infection, Acute Retroviral Syndrome, AIDS, AIDS-Related Complex, Chronic Symptomatic HIV Infection, HIV Infection, Acute, HIV Seroconversion Syndrome, Human Immunodeficiency Virus Infection, Primary HIV Infection, HIV, ARC, Acquired Immunodeficiency Syndrome, HIV/AIDS

Many U.S. AIDS Patients Still Die When 'Opportunistic' Infections Strike

Posted 4 days ago by Drugs.com

WEDNESDAY, July 1, 2015 – Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-related infection died within five years. "The main cause of mortality arises from people stopping treatment entirely," said Dr. Robert Grant, a professor at the University of California, San Francisco, who reviewed the findings but was not involved in the research. When HIV treatment lapses, so-called "opportunistic" infections and illnesses can arise, posing a real threat to patients' health, he explained. The bottom line, according to Grant, is that there is still "a long way to go" in prolonging the lives of Americans with HIV/AIDS. The new study was led by Dr. Sandra Schwarcz, associate professor of epidemiology and biostatistics at the University of California, San Francisco. She and her ... Read more

Related support groups: HIV Infection, Harvoni, Atripla, Tamiflu, Sovaldi, Incivek, Pre-Exposure Prophylaxis, Truvada, Baraclude, Mycobacterium avium-intracellulare, Victrelis, Mycobacterium avium-intracellulare - Treatment, Stribild, Complera, Tenofovir, Viread, Oseltamivir, Entecavir, Sofosbuvir, Kaletra

Sequence of Shots May Lead to Effective HIV Vaccine, Mouse Study Finds

Posted 10 days ago by Drugs.com

THURSDAY, June 25, 2015 – It's unlikely that a single vaccine would ever enable the body to neutralize the HIV virus, but a sequence of immunizations might hold the key, a new mouse study suggests. The immune system could be guided in a series of steps to develop a special type of HIV-fighting antibody, a team of researchers said. Each immunization would be customized for specific stages of the immune system's response to the virus. In the end, the series of shots would result in the production of broadly neutralizing antibodies capable of fighting HIV, the authors said. "As HIV mutates in a patient, the immune system continually adapts. In some patients, this process produces broadly neutralizing antibodies, which are unusual antibodies that can bind to and neutralize a wide range of globally occurring HIV variants. These are the antibodies we want to try to elicit with a vaccine," ... Read more

Related support groups: HIV Infection, Harvoni, Atripla, Sovaldi, Incivek, Pre-Exposure Prophylaxis, Truvada, Baraclude, Victrelis, Stribild, Complera, Tenofovir, Viread, Sofosbuvir, Entecavir, Kaletra, Norvir, Telaprevir, Lamivudine, Ritonavir

Health Assistance to Developing Countries Up Since 1990: Study

Posted 19 days ago by Drugs.com

TUESDAY, June 16, 2015 – There has been an increase in health-related development assistance to low-income countries since 1990, a new study finds. The increased funding has focused mostly on HIV/AIDS, maternal health and newborn and child health. "Understanding how funding patterns have changed across time... may help identify where funding gaps persist and where cost-effective interventions could save lives," Joseph Dieleman, of the Institute for Health Metrics and Evaluation at the University of Washington in Seattle, and colleagues wrote. Even with increased assistance, a child's risk of dying before the age of 5 in a low-income country was 12 times higher than in the United States in 2013. A mother's risk of dying in childbirth was 21 times higher in a low-income country compared to the United States, the researchers noted. Most of these deaths are preventable, they added. ... Read more

Related support groups: HIV Infection

FDA Approves First Pediatric Lopinavir/Ritonavir Oral Pellets for the Treatment of AIDS in Infants and Young Children

Posted 9 Jun 2015 by Drugs.com

Mumbai, India - June 3, 2015 --Cipla Limited, a global pharmaceutical company which uses cutting edge technology and innovation to meet the everyday needs of all patients, today announced that it has received US FDA approval for an innovative formulation - Lopinavir/ritonavir (LPV/r) 40mg/10 mg oral pellets - for pediatric specific treatment for infants. Cipla has long recognized the lack of access to life saving child-friendly formulations for the treatment of HIV, which prompted it to develop an innovative formulation of LPV/r oral pellets. The pellets are to be sprinkled on sweetened porridge for infants and administered to them. The pellets are produced by melt-extrusion technology and are enclosed in capsules. Cipla has been working for many years in collaboration with Diana Gibb, Professor of Epidemiology, Senior Programme Leader and Honorary Consultant Pediatrician at ... Read more

Related support groups: HIV Infection, Kaletra, Lopinavir/Ritonavir

1 in 5 Younger Americans Tested for HIV

Posted 2 Jun 2015 by Drugs.com

TUESDAY, June 2, 2015 – Nearly one-fifth of teens and younger adults in the United States have been tested recently for HIV, federal health officials reported Tuesday. In 2011, more than 1 million Americans 13 and older had HIV, but one in seven did not know their infection status. Routine, voluntary testing is known to reduce transmission of HIV, the virus that causes AIDS, according to the U.S. Centers for Disease Control and Prevention. Researchers at the CDC's National Center for Health Statistics analyzed data from 5,600 females and more than 4,800 males, ages 15-44, who took part in the 2011-2013 National Survey of Family Growth. The researchers found that 19 percent had undergone HIV testing in the past year, an increase from 17 percent in both 2002 and 2006-2010. HIV testing rates in 2011-2013 were 22 percent for females and 16 percent for males, compared with 20 percent for ... Read more

Related support groups: HIV Infection, Harvoni, Atripla, Incivek, Pre-Exposure Prophylaxis, Truvada, Baraclude, Victrelis, Stribild, Complera, Tenofovir, Viread, Entecavir, Kaletra, Norvir, Telaprevir, Lamivudine, Diagnosis and Investigation, Olysio, Reyataz

Global Trial Finds HIV Drugs Should Be Taken Right After Diagnosis

Posted 28 May 2015 by Drugs.com

WEDNESDAY, May 27, 2015 – People with HIV should start taking medications to battle the virus that causes AIDS as soon as they're diagnosed, a new international study finds. Scientists involved in the trial were so impressed by the health benefits of early use of HIV drugs that they shut the study down early so they could offer the medications to all participants. The findings could alter World Health Organization guidelines about the best way to treat people with HIV, experts said. Currently, WHO recommends that HIV patients not start treatment until their immune system show signs of weakening. "We now have clear-cut proof that it is of significantly greater health benefit to an HIV-infected person to start antiretroviral therapy sooner rather than later," Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, said in a statement. "Moreover, ... Read more

Related support groups: HIV Infection, Harvoni, Atripla, Tamiflu, Incivek, Truvada, Baraclude, Victrelis, Stribild, Complera, Tenofovir, Oseltamivir, Viread, Entecavir, Kaletra, Norvir, Telaprevir, Lamivudine, Nevirapine, Lexiva

Hundreds With HIV Could Donate Organs to Others With HIV: Study

Posted 14 May 2015 by Drugs.com

THURSDAY, May 14, 2015 – Nearly 400 HIV-positive potential organ donors in the United States could donate organs each year to HIV-positive people waiting for transplants, a new study estimates. "The findings are significant because there are not enough organ donors in the United States to meet the needs of all of the patients who might benefit from life-saving organ transplants," senior author Dr. Emily Blumberg, a professor in the infectious diseases division at the University of Pennsylvania's Perelman School of Medicine in Philadelphia, said in a university news release. "Some of the patients waiting for organs are infected with HIV but never make it to transplant because they either die while waiting or become too sick to be transplanted. HIV patients who undergo transplantation generally do well, so it is important to continue to look for ways to improve access to transplantation ... Read more

Related support groups: HIV Infection, Organ Transplant

Experimental AIDS Vaccine Targets Hidden Virus

Posted 29 Apr 2015 by Drugs.com

WEDNESDAY, April 29, 2015 – Preliminary research suggests that an AIDS vaccine in development can ramp up the body's immune system, boosting the response to medications HIV-positive patients take. Years of research will be required to confirm that the vaccine works, and researchers don't yet have the major funding needed to continue and push the experimental vaccine toward the market. Still, there's tremendous potential, said study senior author Dr. Barbara Ensoli, director of the National AIDS Center at the National Institute of Health in Rome, Italy. "Although the results are from infected patients, the vaccine may be suitable for both healthy and HIV-infected patients," said Ensoli. So far, she said, the vaccine appears to be well tolerated, with no signs of significant side effects. A vaccine has long been the holy grail of research into AIDS and HIV, the virus that causes the ... Read more

Related support groups: HIV Infection, Harvoni, Atripla, Incivek, Truvada, Baraclude, Victrelis, Stribild, Complera, Tenofovir, Viread, Entecavir, Kaletra, Norvir, Telaprevir, Lamivudine, Reyataz, Lexiva, Efavirenz, Boceprevir

Drug-Related HIV Outbreak Spurs Nationwide Alert

Posted 24 Apr 2015 by Drugs.com

FRIDAY, April 24, 2014 – With narcotic painkiller abuse now linked to 142 cases of HIV in rural Indiana, U.S. health officials are alerting other states to watch for clusters of HIV and hepatitis C among injection drug users. The Scott County epidemic is "a powerful reminder that people who inject drugs are at high risk for both HIV and hepatitis," said Dr. Jonathan Mermin, director of the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. HIV, the AIDS-causing virus, "can gain ground at any time unless we remain vigilant about prevention, testing and care," he said during a Friday morning news conference. There is no indication that HIV infection among injection drug users is spreading beyond this area of Indiana, he said. "But it will be critical to examine all available data on the state and local level to assess whether HIV is increasing among injection drug ... Read more

Related support groups: Hepatitis C, HIV Infection, Toxic Reactions Incl Drug and Substance Abuse

Antibody Holds Promise as Weapon Against HIV

Posted 8 Apr 2015 by Drugs.com

WEDNESDAY, April 8, 2015 – Therapy with a human antibody appears to reduce levels of the HIV virus in the blood for at least a month, preliminary research suggests. Antibodies are the part of the immune system that develop to fight infections. Use of these antibodies as a treatment is called immunotherapy. The antibody "might be able to intensify current treatment strategies," said study co-author Dr. Florian Klein an assistant professor of clinical investigation at Rockefeller University in New York City, especially since this new treatment appears to be more potent than previous attempts at HIV immunotherapy. The researchers acknowledged that this antibody treatment would have to be combined with HIV drugs or another antibody. And much more research is needed before this treatment could even be used as an add-on therapy. The current study represents just the first level of three ... Read more

Related support groups: HIV Infection

HIV Can Damage Brain Early On, Study Says

Posted 2 Apr 2015 by Drugs.com

THURSDAY, April 2, 2015 – HIV can spread to and develop in people's brains in the early stages of infection, new research shows. The findings highlight the need for screening and early treatment of infection with HIV, the virus that causes AIDS, the researchers said. "Any delay runs the risk that the virus could find refuge and cause damage in the brain, where some medications are less effective, potentially enabling it to re-emerge, even after it is suppressed in the periphery," said Dianne Rausch, director of the division of AIDS research at the U.S. National Institute of Mental Health (NIMH). The researchers compared evidence of HIV activity in samples of blood and spinal fluid from 72 untreated HIV-infected patients. The investigators found that 10 percent to 22 percent of the patients showed evidence of HIV replication or inflammation – which suggests an active infectious process ... Read more

Related support groups: HIV Infection

HIV Patients May Fare as Well as Others With Kidney Transplants

Posted 19 Mar 2015 by Drugs.com

THURSDAY, March 19, 2015 – Kidney transplant patients with HIV have similar survival rates as those without HIV, a new study finds. The study included 510 HIV-positive adults who had kidney transplants in the United States between 2002 and 2011. Overall, these patients had similar five- and 10-year survival rates as kidney transplant patients without HIV. However, transplant recipients who had both HIV and hepatitis C had lower survival rates than those without HIV: 69 percent versus 75 percent after five years, and 50 percent versus 54 percent after 10 years, the study found. About 25 percent of kidney transplant patients with HIV also have hepatitis C, according to the study published March 19 in the Journal of the American Society of Nephrology. The findings suggest that excellent results are possible among HIV-positive kidney transplant recipients. However, doctors should be ... Read more

Related support groups: HIV Infection, Renal Transplant

Herpes Drug Might Help Control Spread of HIV, Too

Posted 17 Mar 2015 by Drugs.com

TUESDAY, March 17, 2015 – A widely used herpes drug also seems to help people with the HIV virus, even if those people don't also have herpes, a new small study found. The researchers said their findings challenge the belief that drug Valtrex (valacyclovir) requires the presence of herpes to benefit people with HIV-1. HIV is the virus that causes AIDS. The study included 18 HIV patients in Peru. When patients took Valtrex twice daily for two weeks, they had decreases in HIV-1 levels. Patients taking a placebo saw their HIV levels go up. Experts thought that Valtrex worked against HIV by reducing inflammation caused by the herpes virus. This would give the HIV virus fewer active immune cells to attack, reducing the spread of the virus. But the drug doesn't depend on reducing inflammation to work against HIV, said study co-senior author Dr. Michael Lederman, a professor of medicine at ... Read more

Related support groups: HIV Infection, Valtrex

Half of Known Strains of HIV Originated in Gorillas

Posted 3 Mar 2015 by Drugs.com

MONDAY, March 2, 2015 – Since HIV first appeared in humans in the early 1980s, scientists have been laboring to discover where and how the AIDS-causing virus first developed. Now, an international team of researchers says it has confirmed that two of the four known groups of HIV strains affecting humans originated in western lowland gorillas in Africa. HIV-1 has four known groups, M, N, O and P, explained a team led by Martine Peeters, of the University of Montpellier in France. According to the researchers, prior studies have shown that groups M and N originated in chimpanzees in southern Cameroon. This new study shows that groups O and P originated in western lowland gorillas in Cameroon, the team reported March 2 in the Proceedings of the National Academy of Sciences. Although all four subtypes of HIV can infect humans, only one – Group M, found in Cameroon chimps – eventually ... Read more

Related support groups: HIV Infection

Taking Pill Before, After Sex Cuts HIV Infection for Gay Men: Study

Posted 25 Feb 2015 by Drugs.com

WEDNESDAY, Feb. 25, 2015 – There's new evidence that gay men not infected with HIV can stay that way if they take a pill called Truvada in the days before and after a sexual encounter with an infected partner. The strategy is known as "pre-exposure prophylaxis," or PrEP. Prior studies had suggested that chronic, daily use of Truvada (a combo pill of tenofovir plus emtricitabine) could slash rates of HIV transmission in partners where one person was already infected and the other was not. Now, two new studies – one from Britain and one jointly conducted in France and Canada – appear to bolster those results. They were presented Tuesday at the annual Conference on Retroviruses and Opportunistic Infections in Seattle. The British investigation, called PROUD, involved 500 gay men and seems to reconfirm the effectiveness of standard, once-a-day PrEP. That study found that this dosing ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Truvada

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