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HIV Infection Blog
Related terms: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome (AIDS), Acute HIV Infection, Acute Retroviral Syndrome, AIDS, AIDS-Related Complex, Chronic Symptomatic HIV Infection, HIV Infection, Acute, HIV Seroconversion Syndrome, Human Immunodeficiency Virus Infection, Primary HIV Infection, HIV, ARC, Acquired Immunodeficiency Syndrome, HIV/AIDS
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New HIV Strain May Move to AIDS More Quickly: Study
Posted 7 days ago by Drugs.com
TUESDAY, Dec. 3, 2013 – A recently discovered, aggressive strain of HIV leads to faster development of AIDS than other HIV strains, according to a new study. More than 60 epidemic strains of HIV-1 exist. This new strain has the shortest period from infection to the development of AIDS, at about five years, according to researchers at Lund University, in Sweden. The new strain is a fusion of the two most common strains in Guinea-Bissau, a small country in West Africa. It has been identified only in that region. When two strains join, they form what's called a "recombinant." "Recombinants seem to be more vigorous and more aggressive than the strains from which they developed," doctoral student Angelica Palm said in a Lund University news release. Previous research has shown that the global spread of different recombinants is increasing. Moreover, increasingly mixed and complex HIV ... Read more
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Multivitamins May Help Fight HIV Progression, Study Suggests
Posted 15 days ago by Drugs.com
TUESDAY, Nov. 26, 2013 – New research from Africa suggests that basic multivitamin and selenium supplements might greatly lower the risk that untreated people with the AIDS virus will get sicker over a two-year period. It's not clear how patients who take the vitamins and mineral might fare over longer periods. And the impact of the study in the United States will be limited because many Americans diagnosed with HIV, the virus that causes AIDS, immediately begin treatment with powerful medications known as anti-retroviral drugs. Those in the African study hadn't yet begun taking drugs to keep the virus at bay. Still, "it is incredibly useful to find new strategies to delay the progression of HIV disease," said Dr. Jared Baeten, an associate professor of global health at the University of Washington in Seattle who's familiar with the findings. "Not every HIV-infected person is ... Read more
Related support groups: Vitamins, HIV Infection, Multivitamin, Metanx, Cerefolin, Cerefolin NAC, Neurobion, Thera, StressTabs, Daflon, Folbee, Cod Liver Oil, Folbic, Therobec, Foltx, Estroven, Folbee Plus, Vitaplex, Poly-Vi-Sol, One Tab Daily
Talking Openly With Partner Linked to HIV Testing in Teens
Posted 15 days ago by Drugs.com
TUESDAY, Nov. 26, 2013 – Teens who are in committed relationships and have good communication with their partner are among those most likely to get tested for HIV, a new study finds. Researchers surveyed 980 sexually active teens aged 14 to 17 in the Bronx, where there is a high rate of AIDS. They found that 44 percent of the teens had been tested for HIV, the virus that causes AIDS. Further analysis showed that 60 percent of those who have good HIV-related communication with their partner had been tested. The same was true for 54 percent of those in committed relationships, and 48 percent of those who had good communication and were comfortable discussing sex with their partners. Overall, teens who had high HIV/AIDS-related communication with their parnters were 3.7 times more likely to have been tested for HIV than those with low levels of partner communication, according to the ... Read more
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New Clues to How Long-Term Drug Therapy Keeps HIV at Bay
Posted 15 days ago by Drugs.com
TUESDAY, Nov. 26, 2013 – A new study suggests that the replication of HIV may slow or stop altogether in patients who are on long-term treatment, although remnants can still lurk in the body. And the researchers now suspect that the virus is especially weak in those people who started treatment immediately after becoming infected. The study is very small, involving just eight patients. However, the findings add more evidence to the debate over how soon patients should begin drug treatment after they're diagnosed as being infected with HIV. One of the study authors is ready to say that treatment must begin immediately. "Patients should be started on therapy as soon as they are diagnosed to prevent the virus from hiding in large numbers of cells," said the researcher, Sarah Palmer, deputy director of the Center for Virus Research at Westmead Millennium Institute for Medical Research, in ... Read more
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Bisexual Men Aren't at Greater HIV Risk: Review
Posted 6 Nov 2013 by Drugs.com
WEDNESDAY, Nov. 6 – A review of previous research reveals that bisexual men aren't more likely than heterosexual men to have HIV, the virus that causes AIDS. The findings challenge a common assumption that bisexual men are more likely than heterosexual men to infect their female partners with HIV, said the researchers from the University of Pittsburgh Graduate School of Public Health. "Some observers have exaggerated the idea of viral 'bridging' – where a bisexual man contracts HIV from another man and then transmits it to a female partner," study leader Mackey Friedman, of the school's infectious diseases and microbiology department, said in a university news release. "But, at least in the United States, the data supporting the extent of this is quite limited." The researchers reviewed more than 3,000 scientific reports and found that bisexual men were only 40 percent as likely as ... Read more
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HIV Resistance Mapped by Gene Researchers
Posted 31 Oct 2013 by Drugs.com
THURSDAY, Oct. 31 – Researchers who created the first map of human resistance to HIV say their achievement could lead to improved treatments for the virus, which causes AIDS. When a person is infected with HIV, the immune system tries to destroy the virus. In order to thwart those attacks, HIV undergoes millions of genetic mutations a day. In most cases, this tactic enables HIV to defeat the immune system. However, some people's immune systems manage to hold HIV at bay without any treatment. "The virus survives but replicates more slowly, and thus its capacity for destruction is in some sense neutralized," study co-author Jacques Fellay, of the Swiss Federal Institute of Technology in Lausanne, said in an institute news release. In this study, Fellay and fellow geneticists used a supercomputer to analyze immune system-triggered mutations in the genomes of a variety of strains of HIV ... Read more
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Early HIV Treatment a Win-Win, Researchers Report
Posted 30 Oct 2013 by Drugs.com
WEDNESDAY, Oct. 30 – Providing early antiretroviral drug treatment for recently infected HIV patients and their uninfected sexual partners is a cost-effective way to help patients stay healthy and prevent transmission of HIV, a new study finds. The study, published Oct. 31 in the New England Journal of Medicine, looked at HIV patients in India and South Africa. Some of the patients received early antiretroviral therapy while the start of treatment was delayed for other patients. HIV is the virus that causes AIDS. During the first five years of the study, 93 percent of those who received early antiretroviral therapy survived, compared with 83 percent of those whose treatment was delayed. Life expectancy was nearly 16 years for those in the early treatment group, compared with nearly 14 years for those in the delayed treatment group. During the first five years, the potential costs of ... Read more
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Child 'Cured' of HIV Remains Free of Virus, Doctors Report
Posted 23 Oct 2013 by Drugs.com
WEDNESDAY, Oct. 23 – A 3-year-old Mississippi girl apparently cured of HIV infection by aggressive treatment right after her birth remains free of the virus, her doctors report. Early treatment with a combination of potent antiretroviral drugs appears to have kept the virus from successfully establishing a reservoir in the child's system, said immunologist Dr. Katherine Luzuriaga, of the University of Massachusetts Medical School, who is part of the research team tracking the case. Doctors are hesitant to declare the child fully cured, but in a case update reported in the Oct. 24 issue of the New England Journal of Medicine they said that no actively replicating HIV has been found in her system by even the most sensitive tests available. The girl stopped taking HIV medication when she was 18 months old. A couple of tests have found very low-level indications of HIV in the girl's blood, ... Read more
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Counseling With HIV Testing May Not Help Prevent Future STDs
Posted 22 Oct 2013 by Drugs.com
TUESDAY, Oct. 22 – Contrary to what experts have believed, briefly counseling people who take a rapid HIV test on how to reduce their risk for sexually transmitted diseases (STDs) is not effective, a new study shows. Counseling for these at-risk patients did not reduce the incidence of STDs up to six months after patients were tested for HIV, the study found. A more focused approach to providing information at the time of testing may be needed, the authors said, since counseling requires valuable resources of time, money and personnel. "Overall, these study findings lend support for reconsidering the role of counseling as an essential adjunct to HIV testing," study author Lisa Metsch, at Columbia University's Mailman School of Public Health, and colleagues wrote in the Oct. 23 issue of the Journal of the American Medical Association. "This inference is further buttressed by the ... Read more
Related support groups: HIV Infection, Sexually Transmitted Diseases
Scientists Uncover Breast Milk's Potential Secret Weapon Against HIV
Posted 22 Oct 2013 by Drugs.com
MONDAY, Oct. 21 – Experts have long suspected that breast milk may have the power to prevent babies from getting infected with HIV, and new research gives insight into why that might be so. Researchers say they've discovered a component of breast milk that appears to kill the virus that causes AIDS, potentially preventing some babies from becoming infected by their mothers. "Even though we have anti-retroviral drugs that can work to prevent mother-to-child transmission, not every pregnant woman is being tested for HIV, and less than 60 percent are receiving the prevention drugs – particularly in countries with few resources," study senior author Dr. Sallie Permar, an assistant professor of pediatrics at Duke University, said in a university statement. "There is still a need for alternative strategies to prevent mother-to-child transmission, which is why this work is important." ... Read more
Related support groups: HIV Infection, Dietary Supplementation
Meds That Prevent HIV Infection Don't Spur Risky Behavior: Study
Posted 17 Oct 2013 by Drugs.com
THURSDAY, Oct. 17 – HIV-negative heterosexuals who take drugs that protect them from contracting the AIDS virus from their HIV-positive partners don't engage in more risky sexual behaviors, according to a new study. Researchers from the University of Washington in Seattle found that knowing they are protected against HIV transmission doesn't change how these people behave sexually or lead them to have sex without a condom more often. The study is published in the Oct. 16 issue of the journal The Lancet Infectious Diseases. "Evidence for the effectiveness of new HIV-prevention strategies, including pre-exposure prophylaxis, has spurred optimism that the global HIV epidemic might be reversed," Dr. Jared Baeten said in a journal news release. "However, an important question is whether HIV-negative partners who know they're protected by prophylaxis will compensate for this by increasing ... Read more
Related support groups: HIV Infection, Pre-Exposure Prophylaxis
Nail Fungus Drug Might Help Against HIV, Study Suggests
Posted 23 Sep 2013 by Drugs.com
MONDAY, Sept. 23 – A common drug used to treat nail fungus may hold promise against HIV, the virus that causes AIDS, according to a new study. In laboratory research, the anti-fungal drug Ciclopirox allowed HIV-infected cells to get killed off by blocking the cells' mitochondria – their powerhouse. In addition, Ciclopirox eliminated HIV from cell cultures, and the virus did not return when the anti-fungal drug was stopped, the study authors said. This does not occur with currently available anti-HIV drugs, which must be taken for the rest of a patient's life, said study leaders Michael Mathews and Hartmut Hanauske-Abel, of the Rutgers New Jersey Medical School. The effectiveness of Ciclopirox against HIV needs to be confirmed in human clinical trials. But because the drug is already approved by the U.S. Food and Drug Administration for treatment of fungal infection and is considered ... Read more
Related support groups: HIV Infection, Ciclopirox, Loprox, Penlac, Penlac Nail Lacquer, Pedipirox-4, CNL8 Nail, Loprox TS
Early Course of HIV Therapy May Give Infants a Break From Drugs
Posted 22 Aug 2013 by Drugs.com
WEDNESDAY, Aug. 21 – Giving immediate drug therapy to HIV-infected infants for a limited period of time protects their immune system and delays the start of lifelong treatment, according to a new study. HIV is the virus that causes AIDS. Currently, infants who begin so-called antiretroviral therapy must continue for life. However, long-term use of the therapy increases their risk of drug-related toxicity and drug resistance, according to background information in the study published Aug. 22 in The Lancet. "This important finding indicates we may be able to temporarily stop treatment and spare infants from some of the toxic effects of continuous [antiretroviral therapy] for a while, if we can monitor them carefully," study co-leader Mark Cotton, a professor at Stellenbosch University in South Africa, said in a journal news release. "With [antiretroviral therapy] coverage in children ... Read more
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New Drug Tivicay Approved to Treat HIV-1
Posted 13 Aug 2013 by Drugs.com
TUESDAY, Aug. 13 – Tivicay (dolutegravir) has been approved by the U.S. Food and Drug Administration to treat infection with HIV-1, a strain of the virus that causes AIDS. The drug, among a class called integrase strand transfer inhibitors, interferes with an enzyme that HIV needs to multiply. It's been approved in combination with other antiretroviral drugs and for people aged 12 and older who weigh at least 40 kilograms (approximately 88 pounds), the FDA said in a news release. Some 50,000 Americans acquire HIV infection each year, and about 15,500 people died from the disease in 2010, the agency said, citing the U.S. Centers for Disease Control and Prevention. The drug's safety and effectiveness were evaluated in clinical studies involving more than 2,500 adults and children, the FDA said. The most common side effects included difficulty sleeping, headache and more serious problems ... Read more
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FDA Approves Tivicay (dolutegravir) to Treat HIV Infection
Posted 12 Aug 2013 by Drugs.com
August 12, 2013 – The U.S. Food and Drug Administration today approved Tivicay (dolutegravir), a new drug to treat HIV-1 infection. Tivicay is an integrase strand transfer inhibitor that interferes with one of the enzymes necessary for HIV to multiply. It is a pill taken daily in combination with other antiretroviral drugs. Tivicay is approved for use in a broad population of HIV-infected patients. It can be used to treat HIV-infected adults who have never taken HIV therapy (treatment-naïve) and HIV-infected adults who have previously taken HIV therapy (treatment-experienced), including those who have been treated with other integrase strand transfer inhibitors. Tivicay is also approved for children ages 12 years and older weighing at least 40 kilograms (kg) who are treatment-naïve or treatment-experienced but have not previously taken other integrase strand transfer inhibitors. “ ... Read more
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