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GERD News

Related terms: Heartburn, Acid reflux, Esophageal Reflux, Gastroesophageal Reflux Disease, Pyrosis, Reflux, Heart Burn, Severe Heartburn

Clues to How Popular Heartburn Drug Might Harm Arteries

Posted 16 days ago by Drugs.com

TUESDAY, May 10, 2016 – A popular over-the-counter heartburn medication accelerated aging of blood vessel cells in lab tests, raising red flags about its long-term effect on heart health, researchers say. Faster aging of blood vessel cells exposed to the antacid Nexium (esomeprazole) might potentially hinder the tasks these cells perform to prevent heart attack and stroke, the new study suggests. These lab results could explain why other studies have shown increased risk of heart disease in people who use proton pump inhibitors (PPIs) – the class of heartburn medication that includes Nexium, said study senior author Dr. John Cooke. "Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure," said Cooke, chair of cardiovascular sciences at the ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Protonix, Indigestion, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Tums, Milk of Magnesia, Aciphex, Caltrate, Duodenitis/Gastritis, Calcium Carbonate, Vimovo, Zegerid, Sodium Bicarbonate, Esomeprazole

Common Heartburn Drugs Linked to Kidney Disease in Study

Posted 15 Apr 2016 by Drugs.com

THURSDAY, April 14, 2016 – People who use certain drugs for chronic heartburn may be at increased risk of developing kidney disease, a new study suggests. The research is the latest to highlight potential risks from drugs called proton pump inhibitors (PPIs). PPIs include prescription and over-the-counter drugs, such as Prilosec, Prevacid and Nexium. But prolonged use of PPIs has been linked to certain nutrient deficiencies and bone-density loss. According to the U.S. Food and Drug Administration, bone fractures are considered a safety concern when people use PPIs for a year or more. More recently, research has hinted at additional hazards. Last year, for example, a study tied the medications to a slight increase in heart attack risk. However, neither that study nor this new one prove that PPIs are directly to blame for these problems. "I cannot say for certain that this is ... Read more

Related support groups: GERD, Omeprazole, Prilosec, Renal Failure, Protonix, Pantoprazole, Chronic Kidney Disease, Barrett's Esophagus, Zegerid, Prilosec OTC, Zegerid OTC, Omeclamox-Pak, Omeprazole/Sodium Bicarbonate/Magnesium Hydroxide, Protonix IV, Omeprazole/Sodium Bicarbonate, Renal and Genitourinary Disorders, Omesec, Amoxicillin/clarithromycin/omeprazole

Could a Low-Risk Surgery Help Your Chronic Heartburn?

Posted 30 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – A minimally invasive surgery to treat chronic heartburn is safer than generally believed, and could be a desirable alternative to long-term use of acid reflux medications, new research indicates. Scientists found the death rate following so-called laparoscopic fundoplication surgery for gastroesophageal reflux disease, or GERD, was far lower than the 1 percent often quoted. Experts contended the surgery might be underutilized, especially in light of increasing safety concerns about acid reflux drugs. "One of the main arguments against surgery when choosing between [drug] and surgical treatment for severe GERD is the risk of mortality," said study author Dr. John Maret-Ouda. He is a physician and doctoral student in upper gastrointestinal surgery at the Karolinska Institute in Sweden. But, "this study found only one death associated with [this surgery] among ... Read more

Related support groups: GERD, Indigestion, Endoscopy, Gastrointestinal Disorders, Barrett's Esophagus, Gastric Bypass Surgery, Duodenitis/Gastritis, Gastrointestinal Surgery, Erosive Gastritis, Duodenitis/Gastritis with Hemorrhage, Hypersecretory Conditions

Widely Used Heartburn Drugs Linked to Dementia Risk in Study

Posted 15 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more

Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Protonix, Indigestion, Pantoprazole, Alzheimer's Disease, Stomach Ulcer, Dexilant, Prevacid, Lansoprazole, Gastric Ulcer, Peptic Ulcer, Aciphex, Prevpac, Duodenitis/Gastritis, Vimovo

FDA Approves Takeda's Dexilant SoluTab (dexlansoprazole)

Posted 3 Feb 2016 by Drugs.com

DEERFIELD, Ill., Jan. 27, 2016 /PRNewswire/ – Takeda Pharmaceuticals U.S.A., Inc., (Takeda) (TSE: 4502) today announced that the United States (U.S.) Food and Drug Administration (FDA) approved Dexilant SoluTab delayed-release orally disintegrating tablets, a new formulation of dexlansoprazole that can be taken by allowing the tablet to melt in the patient's mouth. Dexilant SoluTab is a proton pump inhibitor (PPI) indicated for the treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD) and the maintenance of healed erosive esophagitis (EE) and relief of heartburn in adults 18 years and older. Dexilant SoluTab is a PPI with dual delayed release (DDR) technology that is designed to provide two separate releases of medication. "Our more than 20 years of leadership in gastroenterology has allowed us to provide another option that offers ... Read more

Related support groups: GERD, Dexilant, Dexlansoprazole

Heartburn Meds Linked to Chronic Kidney Disease

Posted 11 Jan 2016 by Drugs.com

MONDAY, Jan. 11, 2016 – A type of heartburn medication called proton pump inhibitors may be linked to long-term kidney damage, a new study suggests. Prilosec, Nexium and Prevacid belong to this class of drugs, which treat heartburn and acid reflux by lowering the amount of acid produced by the stomach. People who use proton pump inhibitors (PPIs) have a 20 percent to 50 percent higher risk of chronic kidney disease compared with nonusers, said lead author Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University in Baltimore. The study was published Jan. 11 in JAMA Internal Medicine. The study doesn't establish a direct cause-and-effect relationship between the drugs and chronic kidney disease. However, Grams said, "We found there was an increasing risk associated with an increasing dose. That suggests that perhaps this observed effect is real." Proton pump ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Renal Failure, Protonix, Pantoprazole, Dexilant, Lansoprazole, Prevacid, Chronic Kidney Disease, Aciphex, Zegerid, Rabeprazole, Esomeprazole, Prilosec OTC, Dexlansoprazole, Prevacid SoluTab, Kapidex, Zegerid OTC

Health Tip: Struggling With Chronic Cough?

Posted 22 Dec 2015 by Drugs.com

-- Chronic cough occurs when you've been coughing steadily for eight weeks or longer. It's not always a sign of a serious health problem, but it can be annoying nonetheless. To help calm your chronic cough, the Mayo Clinic suggests: Avoiding exposure to allergens that are known to trigger your cough. Quitting smoking, which is a common cause of chronic bronchitis. Managing acid reflux, which can worsen cough. To help tame acid reflux, cut portion sizes, stay upright for several hours after eating, and sleep with the head of your bed elevated. Read more

Related support groups: Cough, GERD, Allergic Reactions, Allergies, Smoking, Smoking Cessation, Allergic Rhinitis, Hay Fever, Cough and Nasal Congestion, Anaphylaxis, Nasal Polyps, Oral Allergy Syndrome

Frequent Heartburn May Signal More Serious Digestive Problem

Posted 29 Nov 2015 by Drugs.com

THURSDAY, Nov. 26, 2015 – Every Thanksgiving, lots of people loosen their belts and reach for antacids to quell an overstuffed tummy. But for some, turkey day is just another day of severe or persistent heartburn, and that chronic digestive trouble may be a sign of a condition called gastroesophageal reflux disease (GERD), an expert says. In GERD, the contents of the stomach repeatedly flow back into the esophagus. This causes symptoms such as chronic heartburn, regurgitation, difficulty swallowing, sore throat and morning hoarseness, explained Nancy Norton, president and founder of the International Foundation for Functional Gastrointestinal Disorders. "The symptoms of GERD can seem so common that many people do not consult with health care providers or mention them during routine exams," Norton said in a foundation news release. "When symptoms often occur two or more times a week, or ... Read more

Related support groups: Obesity, GERD, Weight Loss, Indigestion, Barrett's Esophagus, Duodenitis/Gastritis, Erosive Gastritis, Laryngopharyngeal Reflux, Hypersecretory Conditions

Don't Let Reflux Ruin Your Thanksgiving

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – Thanksgiving can be challenging if you suffer from heartburn, but there are a number of things you can do to have a more pleasant holiday, an expert says. Certain foods are more likely to cause heartburn and chronic heartburn and should be avoided. These items include fatty and spicy foods, onions, garlic, caffeine, chocolate, citrus fruits and juices, and mints, Dr. Juan Carlos Bucobo, director of endoscopy at Stony Brook University Hospital in New York, said in a hospital news release. "Overeating and eating too fast will increase the chances of heartburn if you are predisposed. Smaller portions separated over time will decrease the chances you will burn in agony. At the main meal, try using a smaller plate and eating slowly," he said. Alcohol – especially in large amounts and particularly red wine – can worsen heartburn. If you drink, do so in ... Read more

Related support groups: GERD, Smoking, Smoking Cessation, Indigestion, Hangover, Acute Alcohol Intoxication

Chronic Heartburn Drugs Tied to Higher Risk of Kidney Disease

Posted 27 Oct 2015 by Drugs.com

TUESDAY, Oct. 27, 2015 – A common type of heartburn medication called proton pump inhibitors (PPIs) seem to be linked with increased risk of chronic kidney disease, two new studies suggest. Prilosec, Nexium and Prevacid belong to this class of drugs, which treat heartburn and acid reflux by lowering the amount of acid produced by the stomach. While the current studies have shown an association between these drugs and the development of chronic kidney disease, they did not prove a cause-and-effect relationship. Still, the lead author of one of the studies believes, "It is very reasonable to assume that PPIs themselves can cause chronic kidney disease," said Dr. Pradeep Arora, a nephrologist and associate professor at the SUNY Buffalo School of Medicine and Biomedical Science in Buffalo, N.Y. "Patients should only use PPIs for [U.S. Food and Drug Administration]-approved indications, and ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, GERD, Hypertension, Omeprazole, Nexium, Prilosec, Renal Failure, Protonix, Indigestion, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Chronic Kidney Disease, Aciphex, Duodenitis/Gastritis, Zegerid, Rabeprazole, Esomeprazole

Health Tip: Should I Talk to my Doctor About Gas?

Posted 10 Aug 2015 by Drugs.com

-- While everyone has intestinal gas, some people have severe bloating that causes discomfort and other problems. The Mayo Clinic mentions these warning signs that you may need to see a doctor: Intestinal gas that is persistent and severe. Intestinal gas that occurs with vomiting. Long-term diarrhea, bloody stool or constipation. Weight loss for no apparent reason. Heartburn. Read more

Related support groups: GERD, Diarrhea, Constipation, Gas, Abdominal Distension, Weight Loss, Colitis, Indigestion, Constipation - Chronic, Hemorrhoids, Gastrointestinal Disorders, Inflammatory Bowel Disease, Duodenitis/Gastritis, Constipation - Acute, Anal Fissure and Fistula, Diarrhea, Chronic, Diarrhea, Acute, Infectious Diarrhea, Functional Gastric Disorder, Acute Abdomen

Health Tip: Identifying Symptoms of GERD

Posted 24 Jun 2015 by Drugs.com

-- Gastroesophageal reflux disease (GERD) occurs when stomach acids back up into the esophagus. The U.S. National Institute of Diabetes and Digestive and Kidney Diseases mentions these symptoms: Having heartburn. Tasting stomach acid or food in the back of the mouth. Having bad breath. Feeling nauseated, or vomiting. Having difficulty breathing or swallowing. Wearing of tooth enamel. Read more

Related support groups: GERD, Indigestion, Helicobacter Pylori Infection, Barrett's Esophagus, Duodenitis/Gastritis, Erosive Gastritis, NSAID-Induced Ulcer Prophylaxis, Hypersecretory Conditions

Popular Heartburn Meds Linked to Higher Risk of Heart Attack

Posted 10 Jun 2015 by Drugs.com

WEDNESDAY, June 10, 2015 – People who use certain heartburn drugs for a long period of time may have a slightly heightened risk of suffering a heart attack, a new study suggests. Using medical records from nearly 300,000 U.S. adults with acid reflux disease (commonly called heartburn), researchers found that the risk of heart attack was slightly elevated among those using proton pump inhibitors. Proton pump inhibitors are a group of acid-suppressing drugs that include brand-names such as Prevacid, Prilosec and Nexium. In 2009, they were the third most commonly used type of drug in the United States, the researchers said. The study, funded by the U.S. National Institutes of Health, does not prove the drugs cause heart attack. And experts were divided over what to make of the connection. Another class of heartburn drug – so-called H2-blockers – was not linked to any increase in heart ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Protonix, Indigestion, Pantoprazole, Dexilant, Prevacid, Lansoprazole, Aciphex, Duodenitis/Gastritis, Zegerid, Rabeprazole, Esomeprazole, Prilosec OTC, Dexlansoprazole, Prevacid SoluTab, Kapidex, Erosive Gastritis

Health Tip: Help Prevent Baby's Spit-Up

Posted 24 Mar 2015 by Drugs.com

-- It's common for babies to spit up after eating, since their small digestive tracts may struggle to keep down an entire meal. The Mayo Clinic suggests these tips: Hold baby in an upright position for feedings, and keep the infant upright for 30 minutes after eating. Hold off on playtime, including baby swings. Feed smaller amounts more frequently, avoiding large feedings. Take regular burp breaks from feeding to help get air out of the belly. Even if baby spits up, always put the infant to bed on the back rather than the belly to help prevent SIDS. If you are nursing, make some changes to your diet to see if it helps baby's problem. Read more

Related support groups: GERD

When Babies Spit Up, Don't Panic

Posted 27 Feb 2015 by Drugs.com

FRIDAY, Feb. 27, 2015 – Some babies spit up more than others, but it doesn't necessarily mean they have a problem, an expert says. A baby's stomach is small and can tolerate only small amounts of food. As a baby grows, so does his or her stomach and spitting up becomes less common, explained Dr. Josephine Dlugopolski-Gach, an assistant professor in the department of pediatrics at Loyola University Chicago Stritch School of Medicine. Also, the esophageal sphincter – the flap that keeps stomach contents from coming back up – is not fully functional in babies, she explained. "Babies typically outgrow spitting up by 6 months. This is when the stomach muscles and the flap that keeps food in the stomach matures. Also, when babies start eating more solid foods and sitting up, spit-up becomes less frequent," Dlugopolski-Gach said in a university news release. "There are medications to help ... Read more

Related support groups: GERD

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