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Early Chemo Less Likely to Help Black Breast Cancer Patients: Study

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Early chemotherapy is less likely to benefit black women with breast cancer than those in other racial and ethnic groups, a new study finds. Advanced breast cancer is more common among black, Hispanic and Asian women than it is in white women. As a result, black women often receive chemotherapy before surgery in an effort to improve their outcomes, the Yale University Cancer Center researchers said. But their study of 27,300 women with stage 1 to 3 breast cancer showed that early (neoadjuvant) chemotherapy was less effective in black patients than in other women. "Even when we controlled for the fact that minority women often present with more advanced-stage, higher-grade tumors, and more aggressive types of breast cancer overall, our team was surprised to find that black women did not respond as well to neoadjuvant chemotherapy compared to other racial groups," ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Zoladex, Breast Cancer, Metastatic, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Herceptin, Casodex, Breast Cancer - Adjuvant

Two Drugs Equal in Preventing Early Breast Cancer's Return: Study

Posted 11 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Postmenopausal women who have an early, noninvasive form of breast cancer had similar recurrence rates of disease whether they took the drug tamoxifen or the aromatase inhibitor anastrozole after surgery, new research shows. However, the side effects of the two medications differed greatly, said study author Jack Cuzick, director of the Wolfson Institute of Preventive Medicine at Queen Mary University of London, England. His team looked at nearly 3,000 women, all past menopause, who had hormone-receptor positive ductal carcinoma in situ (DCIS) breast cancer and underwent surgery to excise it. With DCIS, the cells that line the milk ducts have changed but not spread into the surrounding breast tissue. Half the women were randomly assigned to take 1 milligram (mg) a day of anastrozole (Arimidex), while the other half took 20 mg a day of tamoxifen (Nolvadex). Each ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Zoladex, Breast Cancer, Metastatic, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Herceptin, Casodex, Breast Cancer - Adjuvant

Timing May Be Key to Success of Surgery, Chemo for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – The sooner early stage breast cancer patients have surgery following their diagnosis, and chemotherapy after their surgery, the better their chances of survival, two new studies find. In one study, researchers at Fox Chase Cancer Center in Philadelphia analyzed data from more than 94,500 American women aged 66 and older. All were diagnosed with breast cancer between 1992 and 2009. The team, led by Dr. Richard Bleicher, found a 9 percent increased risk of death from all causes for each 30-day delay in the time from diagnosis to surgery. The link between time to surgery and risk of death from all causes was only statistically significant for patients with earlier stages of cancer, the researchers noted. In the study, delays seemed to affect prognosis for patients with stage 1 and stage 2 cancers, but not for those with stage 3 cancers. The findings were similar ... Read more

Related support groups: Surgery, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Zoladex, Breast Cancer, Metastatic, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Herceptin, Casodex

Depression May Be Tied to Lower Breast Cancer Survival

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Breast cancer patients with depression may have a much higher risk of death than those without the mental illness, a new study suggests. "Low mood and depression are understandable reactions to a breast cancer diagnosis. Clinicians generally know to look out for this, but these findings emphasize the need to ask patients with cancer about their mood and for women to know it's OK to ask for help," Elizabeth Davies, of the division of health and social care research and cancer studies at King's College London, said in a school news release. "It is important women feel they can talk about these feelings and do not feel guilty about difficulty coping or depression, which can be a natural response to cancer diagnosis," she added. Although this study found a link between depression and breast cancer survival, it's important to note that the research can't prove ... Read more

Related support groups: Depression, Zoloft, Cymbalta, Lexapro, Effexor, Prozac, Provera, Paxil, Celexa, Depo-Provera, Citalopram, Pristiq, Sertraline, Major Depressive Disorder, Effexor XR, Fluoxetine, Amitriptyline, Venlafaxine, Breast Cancer, Mirtazapine

Lumpectomy Plus Radiation May Beat Mastectomy for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Women with early stage breast cancer may survive longer if they opt for the less-extensive surgery called lumpectomy, followed by radiation, rather than a mastectomy, a new study suggests. "I think these results offer women important information to discuss with their doctors when making a treatment decision for early stage breast cancer," said lead researcher Sabine Seisling, of the Netherlands Comprehensive Cancer Organization, in Utrecht. Mastectomy removes the entire the breast, while lumpectomy involves removing only the tumor with some surrounding tissue. Some studies have suggested that women with early stage breast cancer have a better five-year survival rate after lumpectomy. The new study, which included 37,000 Dutch women, found that the advantage may also extend to the longer term. Of nearly 22,000 patients who underwent lumpectomy plus radiation, ... Read more

Related support groups: Surgery, Cancer, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Zoladex, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Casodex, Breast Cancer - Adjuvant

Cooling Cap to Reduce Chemo-Linked Hair Loss OK'd

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – The Dignitana Cooling System cap has been approved by the U.S. Food and Drug Administration to help prevent hair loss in women undergoing chemotherapy for breast cancer. A computer-controlled system circulates cooled liquid to the cap during chemotherapy. This is designed to constrict blood vessels in the scalp, limiting the amount of chemotherapy drugs that reach the hair follicles, the agency said in a news release. In clinical testing, more than two-thirds of women who wore the cap reported losing less than half of their hair. And the likelihood of chemotherapy drugs missing an isolated cluster of breast cancer cells in the scalp because of the cap was "extremely rare," the FDA said. But since the cap doesn't work with all chemotherapy drugs, any woman interested in using the product should speak with her doctor, the FDA advised. The most common side ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Alopecia, Arimidex, Lupron Depot, Femara, Zoladex, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Herceptin, Casodex, Breast Cancer - Adjuvant

Drugs May Protect the Heart During Chemotherapy

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Two kinds of medications can prevent heart damage in breast cancer patients as they undergo chemotherapy, a new study suggests. Chemotherapy improves survival among women with early-stage breast cancer, but can dramatically increase their risk of heart failure, the researchers explained. This five-year study of 100 early-stage breast cancer patients in Canada found that two kinds of heart medicines – beta blockers and ACE inhibitors – seem to protect the heart during chemotherapy. "We think this is practice-changing. This will improve the safety of the cancer treatment that we provide," study co-investigator Edith Pituskin, an assistant professor in the Faculty of Nursing and Faculty of Medicine and Dentistry at the University of Alberta in Canada, said in a university news release. The heart medications not only protect the heart, but may also improve ... Read more

Related support groups: Lisinopril, Provera, Depo-Provera, Metoprolol, Atenolol, Breast Cancer, Propranolol, Lupron, Heart Failure, Bystolic, Congestive Heart Failure, Carvedilol, Tamoxifen, Medroxyprogesterone, Bisoprolol, Arimidex, Ramipril, Coreg, Inderal, Lupron Depot

Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Researchers say they're zeroing in on factors that may increase the risk of leukemia after breast cancer treatment. The findings are a step forward in determining ways to prevent this complication in breast cancer survivors. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said. The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. "The findings justify a long-term, follow-up study of women with and without inherited breast cancer gene mutations who are ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Leukemia, Lupron Depot, Femara, Zoladex, Breast Cancer, Metastatic, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Herceptin, Casodex

Risk of More Aggressive Early Breast Cancers Rises With Age, Study Finds

Posted 27 Oct 2015 by Drugs.com

TUESDAY, Oct. 27, 2015 – While experts know the chances of finding a type of early stage breast cancer known as DCIS increase with age, a new study from Germany shows these cancers are more likely to be aggressive when discovered in older women. "DCIS detection rates increase with age, mostly due to a rise of DCIS high- and intermediate-grade [tumors]," said Dr. Stefanie Weigel, a researcher at University Hospital Muenster in Germany. These tumors, she said, are lesions that "carry a higher risk for transition to aggressive cancers than DCIS low-grade." DCIS, or ductal carcinoma in situ, is an early stage cancer that is potentially invasive. It is confined within the milk ducts and a common finding on mammography. Treating DCIS is controversial, because some cases may never progress and cause problems during a woman's lifetime. Weigel's team aimed to look at the link between age at ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Zoladex, Anastrozole, Evista, Megace, Megestrol, Letrozole, Aromasin, Casodex, Eligard, Exemestane, Lupron Depot 3.75 mg

For Unexplained Infertility, Breast Cancer Drug No Better Than Standard Treatment

Posted 23 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 23, 2015 – A breast cancer drug that is sometimes used to treat infertility may reduce a couple's risk of having a pregnancy with multiple babies – but it might also slightly lower their chances of having a baby at all, a new clinical trial suggests. The study did not find the cancer drug letrozole (Femara) more effective than standard fertility drugs for women with unexplained infertility. In research reported last year, letrozole actually improved birth rates among women who were infertile due to polycystic ovarian syndrome compared to a widely used fertility drug called clomiphene (Clomid). In contrast, the new study focused on women age 40 and younger whose infertility had no clear cause. "For them, we can't say that letrozole is as good as standard drugs when it comes to your chances of going home with a baby," said lead researcher Dr. Michael Diamond, professor ... Read more

Related support groups: Polycystic Ovary Syndrome, Clomid, Female Infertility, Femara, Letrozole, Ovulation Induction, Clomiphene, Primary Ovarian Failure, Serophene, Follicle Stimulation, Milophene

After Breast Cancer, Many in Appalachia Say No to Lifesaving Drugs

Posted 27 Jul 2015 by Drugs.com

MONDAY, July 27, 2015 – About one-third of breast cancer survivors in the Appalachian region of the United States do not take potentially lifesaving drugs, even though their drugs are covered by insurance, a new study finds. The study included 428 breast cancer survivors in the Appalachian counties of Kentucky, Ohio, North Carolina and Pennsylvania. All of the women had Medicare Part D insurance that covers prescription medications. About 30 percent of the women did not follow through with their prescribed adjuvant hormone therapy, which reduces the risk of cancer recurrence, the University of Virginia researchers discovered. "Almost a third of the prescriptions for adjuvant hormone therapy were not filled, which is much, much higher compared to what we usually see in commercially insured populations," Rajesh Balkrishnan, of the department of public health sciences, said in a ... Read more

Related support groups: Breast Cancer, Tamoxifen, Arimidex, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Aromasin, Breast Cancer - Adjuvant, Exemestane, Breast Cancer, Prevention, Breast Cancer - Palliative, Tamoxifen Hexal, Nolvadex, Testolactone, Soltamox, Tamone, Emblon, Tamoxen, Genox

Certain Generic Meds May Help Older Patients With Early Breast Cancer

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – There's more evidence that two classes of inexpensive generic drugs reduce the risk of death in postmenopausal women with early breast cancer, a pair of new British studies find. The two classes of drugs – called aromatase inhibitors and bisphosphonates – can also be used together to increase the benefits and reduce some side effects, according to the authors of the studies published July 23 in The Lancet. Aromatase inhibitors include drugs such as anastrozole, letrozole and exemestane, while bisphosphonates include drugs such as zoledronic acid. The two new studies "provide really good evidence that both of these inexpensive generic drugs can help to reduce breast cancer mortality in postmenopausal women," Richard Gray, the University of Oxford lead statistician for both studies, said in a journal news release. The studies were released by The Early Breast ... Read more

Related support groups: Breast Cancer, Fosamax, Arimidex, Boniva, Femara, Alendronate, Reclast, Anastrozole, Actonel, Letrozole, Aromasin, Zometa, Breast Cancer - Adjuvant, Exemestane, Aclasta, Zoledronic Acid, Atelvia, Ibandronate, Risedronate, Breast Cancer, Prevention

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Tretinoin, Gleevec, Fluorouracil, Lung Cancer, Rituxan, Colorectal Cancer, Zoladex

Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study

Posted 3 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Many men on hormone therapy for prostate cancer aren't getting bone-strengthening drugs they may need, new Canadian research contends. Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. But one consequence of the treatment is weakening of the bones, which can lead to fractures. To reduce this risk, men can be given oral bisphosphonates, such as Fosamax, or an intravenous treatment once a month or once a year with similar drugs, such as Reclast. "There seems to be a clear mismatch between Canadian guidelines regarding bisphosphonate usage in men undergoing hormone therapy for prostate cancer and actual clinical practice," said lead researcher Dr. Shabbir Alibhai, a senior scientist at the University Health Network in Toronto. While the low rates of bisphosphonate prescriptions may be appropriate for patients ... Read more

Related support groups: Provera, Depo-Provera, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Fosamax, Arimidex, Lupron Depot, Femara, Boniva, Tretinoin, Zoladex, Alendronate, Claravis, Isotretinoin, Reclast, Anastrozole, Actonel

Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Provera, Depo-Provera, Amoxicillin, Doxycycline, Metronidazole, Methotrexate, Clindamycin, Penicillin, Cephalexin, Bactrim, Azithromycin, Cipro, Accutane, Ciprofloxacin, Lupron, Augmentin, Levaquin, Flagyl, Zithromax, Keflex

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