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Related terms: Cancer, Endometrial, Cancer, Uterine, Endometrial Adenocarcinoma, Endometrial Carcinoma, Uterine Adenocarcinoma, Uterine Cancer, Uterine corpus cancer

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Research Sheds Light on Gene Mutation's Role in Rare Tumors

Posted 21 Dec 2011 by Drugs.com

WEDNESDAY, Dec. 21 – Mutations in a gene called DICER are associated with rare, seemingly unrelated ovarian, uterine and testicular cancers, a new study finds. The Canadian researchers said they were surprised to discover that the same fundamental mutation in the DICER gene was the common process underlying all these different cancers. The study was published in the Dec. 21 issue of the New England Journal of Medicine. "DICER is of great interest to cancer researchers," team leader Dr. David Huntsman, a genetic pathologist and director of the Ovarian Cancer Program of B.C. at the British Columbia Cancer Agency and Vancouver Coastal Health Research Institute, said in a University of British Columbia news release. "There have been nearly 1,300 published studies about it in the last 10 years, but until now, it has not been known how the gene functions in relation to cancer," said ... Read more

Related support groups: Ovarian Cancer, Endometrial Cancer, Testicular Cancer

Study Links Coffee to Lower Risk of Endometrial Cancer

Posted 22 Nov 2011 by Drugs.com

TUESDAY, Nov. 22 – Women who drink moderate to high amounts of coffee may reduce their risk for endometrial cancer, new research reveals. The finding stems from what investigators call the largest study to date to explore the impact of coffee and tea on the risk of endometrial cancer, which is cancer that originates in the lining of the uterus. The study found that women who consume four or more cups of caffeinated coffee per day appear to lower their risk for endometrial cancer by 25 percent, relative to women who drink less than one cup a day. Drinking fewer than four cups a day did not appear to offer any preventative benefit, however. Nor did drinking tea. But there was some indication that decaffeinated coffee might be helpful, as drinking two or more cups of decaf daily was linked (although only tentatively) to a 22 percent drop in endometrial cancer risk. Still, "this study does ... Read more

Extra Pounds Suspected in Raised Endometrial Cancer Risk

Posted 24 Oct 2011 by Drugs.com

SUNDAY, Oct. 23 – Gaining a significant amount of weight after menopause may be associated with an increased risk of developing endometrial cancer, a new study suggests. "Fat tissue is the major source of circulating estrogen in postmenopausal women, and estrogen promotes the development of endometrial cancer," Victoria L. Stevens, strategic director of laboratory services at the National Home Office of the American Cancer Society in Atlanta, said in a news release from the American Association for Cancer Research. In conducting the study, the researchers analyzed the weight history of more than 38,000 postmenopausal women who completed a survey in 1992. By 2007, 560 of the women had been diagnosed with endometrial cancer. This is a cancer of the uterus, affecting the uterine lining. After adjusting for body mass index (a measurement that takes into account height and weight), the ... Read more

Related support groups: Endometrial Cancer

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Fewer Cancer Patients May Be Depressed Than Thought

Posted 20 Jan 2011 by Drugs.com

THURSDAY, Jan. 20 – The rate of depression among cancer patients may be lower than previously believed, a new study indicates. An international team of researchers analyzed 94 studies involving more than 14,000 patients and found that about one-sixth of cancer patients suffer depression and about one-third have a more widely defined mood disorder. Only modest rates of depression and anxiety occurred in cancer patients in the first five years after diagnosis, which suggests that depression is not inevitable in these patients, the researchers said. Only when it was combined with other mood disorders was depression common, occurring in 30 percent of hospitalized cancer patients. The study is published online Jan. 19 in The Lancet Oncology. Rates of depression and anxiety were not significantly different between patients receiving palliative care (care designed to ease pain and increase ... Read more

1 in 5 Cancer Survivors Suffers Chronic Pain, Study Finds

Posted 20 Jan 2011 by Drugs.com

WEDNESDAY, Jan. 19 – More than 40 percent of cancer survivors experience pain, and the risk is highest among black and female patients, finds a new study. Researchers at the University of Michigan Health System surveyed nearly 200 U.S. cancer survivors and found that 43 percent had experienced pain since their diagnosis, and 20 percent suffered chronic cancer-related pain at least two years later. Among white patients, the most significant source of pain was cancer surgery (53.8 percent), and among black patients the greatest source of pain was cancer treatment (46.2 percent), according to the report. In addition, the study found that compared to men, women had more pain, more pain flare-ups, more disability due to pain and were more depressed because of pain. The authors also noted that black patients were more likely to report greater severity of pain and more pain-related ... Read more

Demand for Radiation Therapy Predicted to Exceed Supply

Posted 21 Oct 2010 by Drugs.com

THURSDAY, Oct. 21 – Over the next decade, the growth in demand for radiation therapy in the United States will be 10 times greater than the increase in new radiation oncologists, a difference that could affect cancer patients' access to treatment, according to a new study. Between 2010 and 2020, the number of patients requiring radiation therapy will increase 22 percent but the number of full-time radiation oncologists entering the workforce will increase just 2 percent, said researchers at the University of Texas M.D. Anderson Cancer Center in Houston and colleagues. They based their predictions on projections that this year 3,943 radiation oncologists will treat an estimated 470,000 patients in the United States. The large increase in demand for radiation therapy will be partly due to growing numbers of older adults and minorities, groups in which certain types of cancers are more ... Read more

Cancer Patients' Secondary Symptoms Need Attention: Study

Posted 11 Oct 2010 by Drugs.com

MONDAY, Oct. 11 – Many cancer patients with pain or depression also experience physical symptoms, such as fatigue, dry mouth and nausea, that can cause disability, a new study shows. Doctors need to recognize and treat these symptoms in order to improve quality of life for cancer patients, said Dr. Kurt Kroenke, of the Richard Roudebush VA Medical Center, Indiana University, and Regenstrief Institute Inc. in Indianapolis, and colleagues. They analyzed data from 405 cancer patients who had either pain or depression and found that all the patients had at least one of 22 physical symptoms examined in the study. More than half of patients reported 15 of the 22 symptoms. The most common symptoms were fatigue (97.5 percent), difficulty sleeping (about 79 percent), pain in limbs or joints (78 percent), back pain (nearly 75 percent) and memory problems (72 percent). The patients also reported ... Read more

IUD Proposed to Treat Uterine Cancer

Posted 29 Sep 2010 by Drugs.com

WEDNESDAY, Sept. 29 – An intrauterine device that releases a progestin hormone may be an effective treatment for younger women with early-stage uterine cancer, Italian researchers report. By delaying a total hysterectomy, which is the usual treatment for endometrial cancer, the IUD allows women to remain fertile and possibly to have families, according to the study published online Wednesday in Annals of Oncology, the monthly journal of the European Society for Medical Oncology. "The study was done to see if this was a viable option for younger women who want to preserve fertility," said Dr. Jamie Bakkum-Gamez, senior associate consultant in the division of gynecologic surgery at the Mayo Clinic in Rochester, Minn. "We see it as buying more time to have a family and, once that's completed, to have a hysterectomy." "It's a very important trial," added Dr. Angeles Alvarez Secord, ... Read more

Related support groups: Endometrial Cancer

Many Docs Deliver Cancer Diagnosis Badly: Study

Posted 7 Jul 2010 by Drugs.com

WEDNESDAY, July 7 – One patient found out he had cancer by reading his radiology report. Another got the news when her neurologist called to say he had arranged for her to see a neurosurgeon. When she asked why, the doctor told her she had a brain tumor and hung up. A third learned she had breast cancer listening to her answering machine with her grandson sitting on her lap. A new study about how people learn of cancer diagnoses finds that many doctors have poor communication skills and often leave patients stranded with devastating information about a deadly illness, sometimes in a public setting. One-third of the cancer patients in the U.S. National Cancer Institute study recalled being told on the phone, in an emergency room, radiology department or other public hospital setting that they had cancer, most often leukemia, lymphoma or brain tumors. "It's really dismaying to think that ... Read more

Cost-Conscious Cancer Survivors Skip Care

Posted 14 Jun 2010 by Drugs.com

MONDAY, June 14 – Millions of Americans with a history of cancer, particularly people under age 65, are delaying or skimping on medical care because of worries about the cost of treatment, a new study suggests. The finding raises troubling questions about the long-term survival and quality of life of the 12 million adults in the United States whose lives have been forever changed by a diagnosis of cancer. "I think it's concerning because we recognize that cancer survivors have many medical needs that persist for years after their diagnosis and treatment," said study lead author Kathryn E. Weaver, an assistant professor in the Department of Social Sciences & Health Policy at Wake Forest University Baptist Medical Center in Winston-Salem, N.C. The report was published online June 14 in Cancer, a journal of the American Cancer Society. Cost concerns have posed a threat to cancer ... Read more

Pain Relief Often Delayed for Cancer Patients

Posted 16 Mar 2010 by Drugs.com

TUESDAY, March 16 – Palliative care services, which help people who are seriously ill relieve symptoms such as pain, are now found at most U.S. cancer centers, but many programs don't interact with patients until it's too late, study findings show. Dr. David Hui, of the University of Texas M.D. Anderson Cancer Center in Houston, and his colleagues surveyed 71 U.S. National Cancer Institute-designated cancer centers and randomly surveyed 71 other cancer centers. They received responses from 71 percent of 142 executives and 82 percent of 120 program leaders. The researchers also found that the NCI cancer centers were more likely to have palliative care programs and physicians. A report on the survey was published in the March 17 issue of the Journal of the American Medical Association. "Palliative care outpatient clinics, inpatient consultation teams, palliative care units and hospices ... Read more

Removing Lymph Nodes May Boost Endometrial Cancer Survival

Posted 25 Feb 2010 by Drugs.com

THURSDAY, Feb. 25 – Endometrial cancer patients at medium to high risk for cancer recurrence are more likely to survive if both the pelvic lymph nodes and para-aortic lymph nodes are removed, rather than just the pelvic lymph nodes, say Japanese researchers. The para-aortic lymph nodes, which are located in front of the lumbar vertebral bodies near the aorta, receive drainage from the lower gastrointestinal tract and the pelvic organs, according to a news release about the study. The study included 671 women with endometrial cancer who had pelvic lymph nodes removed or both pelvic and para-aortic lymph nodes removed. Women at medium or high risk for cancer recurrence were offered additional treatment in the form of chemotherapy or radiotherapy. Those at medium to high risk for recurrence who had both pelvic and para-aortic lymph nodes removed were 56 percent less likely to die than ... Read more

Related support groups: Endometrial Cancer

U.S. Cancer Cases, Deaths Continue to Drop

Posted 8 Dec 2009 by Drugs.com

MONDAY, Dec. 7 – Better screening, healthier living and new treatments have all continued to help cut the annual number of cancer cases and deaths in the United States, a new report says. The findings showed that new cancer cases and deaths from cancer have declined significantly for both men and women and for most racial/ethnic populations. These decreases were largely due to decreased incidence and death from lung, prostate and colon cancer among men and a drop in two of the three leading cancers in women (breast and colon cancers). New diagnoses for all types of cancer in the United States declined almost 1 percent per year from 1999 to 2006 and cancer deaths dropped 1.6 percent per year from 2001 to 2006. The report, which appears in the Dec. 7 online edition of Cancer, was compiled from data by the American Cancer Society, the U.S. Centers for Disease Control and Prevention, the ... Read more

Obesity Greatly Raises Endometrial Cancer Risk

Posted 22 Jun 2009 by Drugs.com

MONDAY, June 22 – Obesity is already linked to heart disease, diabetes and high blood pressure, but new research finds those extra pounds can also significantly increase a woman's risk of developing endometrial cancer, especially if she experiences early menopause. Published in the July issue of Obstetrics & Gynecology, the study found that women with a body-mass index (BMI) greater than 35 who were under 45 at the time of their last menstrual period had a 22 times higher risk of developing endometrial cancers than their normal-weight peers. "In this young population, the risk of endometrial cancer increased dramatically if they had a BMI greater than 25," said study author Cheryll C. Thomas, an epidemiologist at the U.S. Centers for Disease Control and Prevention. Body-mass index is a measurement used to estimate one's body fat. A BMI between 18.5 and 24.9 is considered normal, ... Read more

Related support groups: Obesity, Endometrial Cancer

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