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Painkillers Don't Ease Disability Due to Nerve Damage: Study

Posted 11 days ago by Drugs.com

MONDAY, Feb. 1, 2016 – Taking prescription narcotic painkillers doesn't improve movement or reduce disability in people with pain related to nerve damage, researchers have found. "Even though [narcotic] medications can be a powerful pain killer, it does not necessarily mean improved function will follow. Pain is not the only factor in determining function," study lead author and pain expert Geoff Bostick, an associate professor of physical therapy at the University of Alberta in Canada, said in a university news release. The research included almost 800 patients with pain due to nerve damage, from causes such as diabetes and pinched nerves. Some were prescribed narcotic painkillers – such as morphine, codeine and Tylenol 3 – while others didn't receive the drugs. At 6-month and 12-month follow-ups, those who took the painkillers didn't show greater improvements in movement and ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Methadone, Fibromyalgia, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Morphine, Fentanyl, Lortab, Codeine, Opana, Tylenol, Chronic Pain, Subutex, Neuralgia

New Transplant Technique Might Free Type 1 Diabetics From Daily Injections

Posted 16 days ago by Drugs.com

WEDNESDAY, Jan. 27, 2016 – Using a two-pronged approach, researchers report they were able to restore normal blood sugar levels for six months in mice with induced diabetes. But, while the research is promising, it's too soon for people with type 1 diabetes to start planning a life free of needles and injections just yet, experts said. The first part of the treatment was using insulin-producing pancreas cells generated from human stem cells employing a technique recently developed at Harvard. But the latest breakthrough came from MIT researchers, who developed a way to encapsulate the cells – called islet cells – before they were implanted in the mice, to protect them from the immune system. That's key for two reasons. One is that when you introduce foreign cells into the body, the immune system recognizes them as foreign and destroys them. This is why people who have organ ... Read more

Related support groups: Diabetes, Type 1, Diabetic Neuropathy, Diabetic Nerve Damage, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Organ Transplant, Diabetic Retinopathy, Diabetic Ketoacidosis (DKA), Abnormal Glucose Tolerance, Intravenous Insulin Drip, Diabetic Coma

Nasal Spray May Give Diabetics Faster Treatment for Low Blood Sugar

Posted 18 Dec 2015 by Drugs.com

FRIDAY, Dec. 18, 2015 – A new nasal spray might make rescue care easier for diabetics who are woozy or even unconscious due to severe low blood sugar, a new clinical trial suggests. The nasal spray contains powdered glucagon, a hormone that causes a prompt increase in blood sugar levels. The trial results showed that the nasal spray is nearly as effective in treating hypoglycemia (low blood sugar) as the only option currently available, a glucagon powder that must be mixed with water, drawn into a syringe and then injected into muscle. Because it is almost as effective but much easier to administer to an ailing person, the nasal spray could become the go-to treatment for severe hypoglycemia, said Dr. George Grunberger, a clinical professor at Wayne State University School of Medicine in Detroit and president of the American Association of Clinical Endocrinologists. He was not involved ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetic Neuropathy, Hypoglycemia, Diabetic Nerve Damage, Insulin Resistance, Pre-Diabetes, Diabetes Insipidus, Diabetes Mellitus, Diabetic Ketoacidosis (DKA), Diabetic Retinopathy, Glucagon, Abnormal Glucose Tolerance, Diabetic Ketoacidosis (in DM Type II), Diabetic Ketoacidosis (in DM Type I), GlucaGen, Diabetic Coma (in DM Type I), Diabetic Coma, Diabetic Coma (in DM Type II), Intravenous Insulin Drip

Health Tip: Keeping Diabetes in Check During the Holidays

Posted 18 Dec 2015 by Drugs.com

-- The holidays are a time of busy schedules, get-togethers and lots of food. If you have diabetes, it can be a tricky time of year. The U.S. Centers for Disease Control and Prevention offers these suggestions: Stick to your regular plans for exercise, diet and sleep schedule as much as possible. Eat regularly throughout the day, and use only a small plate. Fill up first on fruits, veggies and healthy fare, avoiding heavier recipes and alcohol. Check blood sugar often, ideally more often than usual. Read more

Related support groups: Diabetes, Type 2, Diabetic Neuropathy, Diabetic Nerve Damage, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Gestational Diabetes, Abnormal Glucose Tolerance

Metformin May Not Help Obese Teens With Type 1 Diabetes

Posted 2 Dec 2015 by Drugs.com

TUESDAY, Dec. 1, 2015 – Metformin is the standby drug for millions of people with type 2 diabetes, but a new study finds that adding it to insulin therapy won't boost blood sugar control for overweight teens with type 1 diabetes. In type 1 diabetes, which comprises about 5 percent of diabetes cases, the body is unable to produce the insulin it needs. So, supplemental insulin is a must for people with the disease. The new study was led by Kellee Miller of the Jaeb Center for Health Research in Tampa, Fla. As her team explained, young people with type 1 diabetes are at even higher metabolic risk if they become overweight or obese, especially in adolescence. That's because both obesity and puberty may cause the patient to require higher levels of supplemental insulin, complicating blood sugar control, the researchers said. Metformin – a pill taken to help lower blood sugar – is widely ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Diabetes, Type 1, Glucophage, Diabetic Neuropathy, Janumet, Diabetic Nerve Damage, Pre-Diabetes, Diabetes Mellitus, Glucophage XR, ActoPlus Met, Glumetza, Glyburide/Metformin, Avandamet, Jentadueto, Glucovance, Janumet XR, Metformin/Pioglitazone, Riomet

Health Tip: Stay Well Despite Diabetes

Posted 24 Nov 2015 by Drugs.com

-- Managing diabetes is a long-term job that requires careful planning to stay on top of your health. The U.S. Centers for Disease Control and Prevention advises: Take daily steps to eat well, get exercise, inspect feet for wounds and take your medication. At each quarterly doctor visit, have a foot check and blood pressure check. Twice yearly, have a dental checkup and an A1C check. Once annually, have a cholesterol test and a test for kidney function. Get all doctor-recommended vaccines, including the annual one for flu. Have annual visits with an eye doctor and podiatrist. Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetic Neuropathy, Diabetic Nerve Damage, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance, Gestational Diabetes

Health Tip: Diabetes Can Take a Toll on Teeth and Mouth

Posted 10 Aug 2015 by Drugs.com

-- Diabetes, especially when uncontrolled, can cause damage to your mouth and teeth. The Mouthhealthy.org website says possible effects of diabetes on the teeth and mouth include: Dry mouth, due to decreased saliva production. Increased risk of cavities due to less saliva. Gingivitis, characterized by bleeding, inflamed gums. Difficulty tasting food. Slower healing of mouth wounds. Increased risk of infection. Among diabetic children. teeth emerging earlier than expected. Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Oral and Dental Conditions, Xerostomia, Lantus, Diabetes, Type 1, Januvia, Glucophage, Toothache, Novolog, Glipizide, Humalog, Diabetic Neuropathy, Burning Mouth Syndrome, Janumet, Byetta, Glyburide, Diabetic Nerve Damage

Uncontrolled Diabetes May Boost Dementia Risk

Posted 9 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – Diabetes patients with high rates of complications from the disease may face increased risk for dementia, a new study suggests. "We found that as diabetes progresses and an individual experiences more complications from the disease, the risk of dementia rises as well," wrote Dr. Wei-Che Chiu, of the National Taiwan University College of Public Health, in Taipei. Better blood sugar control can help prevent the mental decline associated with diabetes, he and his colleagues said. They examined data from more than 431,000 people in Taiwan who were older than 50 and newly diagnosed with diabetes. Complications of diabetes include vision loss, kidney failure and nerve damage. Over 12 years of follow-up, more than 6 percent of the patients were diagnosed with dementia. Those with a greater number of diabetes complications were at higher risk for mental decline than ... Read more

Related support groups: Diabetes, Type 2, Peripheral Neuropathy, Dementia, Diabetes, Type 1, Alzheimer's Disease, Diabetic Neuropathy, Diabetic Nerve Damage, Pre-Diabetes, Diabetic Kidney Disease, Mild Cognitive Impairment, Diabetes Mellitus, Diabetic Nephropathy, Arteriosclerotic Dementia, Diabetic Retinopathy, Abnormal Glucose Tolerance, Retinopathy Prophylaxis, Lewy Body Dementia

Health Tip: If You Have Peripheral Neuropathy

Posted 9 Jun 2015 by Drugs.com

-- Peripheral neuropathy, common among people with diabetes, is characterized by nerve damage in the fingers and toes. The American Podiatric Medical Association says people with peripheral neuropathy should: Regularly inspect the feet for wounds and signs of infection, since feeling to the feet may be reduced. Ask someone else to inspect the feet if unable to do so. Seek immediate care for any foot injury. Don't walk barefoot. Always wear sturdy, well-fitted shoes. Keep blood sugar under control and follow a diabetes treatment plan. Read more

Related support groups: Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage, Foot Care

Vegan Diet Might Ease Diabetic Nerve Pain

Posted 27 May 2015 by Drugs.com

WEDNESDAY, May 27, 2015 – A vegan diet might help people with diabetes-related nerve damage shed weight and find some pain relief, a small pilot study suggests. Vegan diets are free of all animal products, including eggs and dairy. Instead, people get their protein, fat and all other nutrients from foods such as beans, nuts, whole grains, vegetables, fruit and plant-based oils. In the new study, researchers tested whether a vegan diet could help people with type 2 diabetes and painful nerve damage in their feet or hands. The investigators found that over 20 weeks, the 17 people they assigned to the diet lost an average of 15 pounds. At the same time, blood flow to their feet improved and their pain eased up. Experts said the findings, reported May 25 in the journal Nutrition & Diabetes, highlight the importance of healthy eating and weight loss for people with type 2 diabetes. But it's ... Read more

Related support groups: Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Nerve Damage

Sleep Apnea Treatment May Help Lower Diabetes Risk for Some

Posted 6 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – Treating sleep apnea may help people with slightly elevated blood sugar levels lower their risk of developing diabetes, according to a new study. "Assessment of sleep apnea should be considered in patients at high risk for diabetes and cardiovascular disease, since our study shows that treatment of sleep apnea can reduce these risks," the study's senior author, Dr. Esra Tasali, an assistant professor of medicine at the University of Chicago, said in a university news release. People with higher-than-normal blood sugar levels who don't yet have diabetes are considered to have pre-diabetes. This condition affects about 57 million Americans, according to the researchers. Many people with pre-diabetes also have untreated sleep apnea – a sleep disorder that causes the upper airway to close repeatedly during the night, disrupting sleep and temporarily reducing oxygen ... Read more

Related support groups: Diabetes, Type 2, Obesity, Diabetic Neuropathy, Diabetic Nerve Damage, Insulin Resistance, Sleep Apnea, Pre-Diabetes, Diabetes Mellitus, Cardiovascular Risk Reduction, Obstructive Sleep Apnea/Hypopnea Syndrome, Diabetic Retinopathy, Abnormal Glucose Tolerance, Retinopathy Prophylaxis

FDA Approves Nucynta ER (tapentadol) Extended-Release Oral Tablets for the Management of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Posted 29 Aug 2012 by Drugs.com

RARITAN, N.J., Aug. 29, 2012 /PRNewswire/ – Janssen Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Nucynta ER (tapentadol) extended-release tablets, an oral analgesic taken twice daily, for the management of neuropathic pain associated with diabetic peripheral neuropathy (DPN) in adults when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Nucynta ER is the first and only opioid approved by the FDA for neuropathic pain associated with DPN. In addition to this new indication, Nucynta ER is currently approved for the management of moderate to severe chronic pain in adults when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Diabetes affects nearly 26 million people in the United States, and approximately 60 to ... Read more

Related support groups: Nucynta, Diabetic Nerve Damage, Tapentadol

Pain Reported by Nearly Half With Type 2 Diabetes

Posted 14 Aug 2012 by Drugs.com

TUESDAY, Aug. 14 – Nearly 50 percent of patients with type 2 diabetes say they have acute and chronic pain, and about one-quarter suffer from a wide range of symptoms, including nerve damage, fatigue and depression, a new study indicates. As a result, specialized treatment, called palliative care, that focuses on relieving symptoms and improving quality of life should be a normal part of diabetes management, the researchers suggest. "Adults living with type 2 diabetes are suffering from incredibly high rates of pain and non-pain symptoms, at levels similar to patients living with cancer," lead study author Dr. Rebecca Sudore, a staff physician at San Francisco VA Medical Center and associate professor of medicine at the University of California, San Francisco, said in a news release that was released jointly by the medical center, the university and Kaiser Permanente. "Palliative care ... Read more

Related support groups: Diabetes, Type 2, Diabetic Neuropathy, Diabetic Nerve Damage

Sleep Apnea May Be Linked to Nerve Damage in Diabetics

Posted 18 Jun 2012 by Drugs.com

MONDAY, June 18 – Obstructive sleep apnea is associated with nerve damage in people with type 2 diabetes, according to a new study. The severity of this type of nerve damage – called diabetic peripheral neuropathy – is linked with the extent of sleep apnea and the degree of low blood oxygen levels that occur while patients sleep, the researchers found. People with obstructive sleep apnea subconsciously awaken many times a night – even dozens of times an hour – because their airways close, disrupting their breathing. Those with diabetic peripheral neuropathy may have numbness or tingling in their extremities, or damage to their major organs. The study of 234 adults with type 2 diabetes found that sleep apnea was independently associated with diabetic peripheral neuropathy even after the researchers accounted for a number of other possible factors, including obesity, ethnicity, ... Read more

Related support groups: Diabetes, Type 2, Diabetic Neuropathy, Diabetic Nerve Damage, Sleep Apnea

Exercise Appears to Ease Nerve-Damage Pain in Rat Study

Posted 6 Jun 2012 by Drugs.com

WEDNESDAY, June 6 – Exercise helps reduce pain from nerve damage caused by injury, diabetes and other conditions, according to a study involving rats. Researchers found that exercise appears to ease this type of pain – called neuropathic pain – by reducing levels of inflammation-causing substances called cytokines. Neuropathic pain is common but hard to treat. These findings suggest that exercise could provide an effective non-drug treatment for neuropathic pain, according to lead author Yu-Wen Chen, of China Medical University in Taiwan, and colleagues. The study was published in the June issue of the journal Anesthesia & Analgesia. For the study, researchers injured the sciatic nerve in rats and had them do exercise – either swimming or treadmill running – over a few weeks. These rats showed a 30 percent to 50 percent reduction in neuropathic pain, as assessed by their responses ... Read more

Related support groups: Diabetic Neuropathy, Diabetic Nerve Damage

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