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Diabetic Nerve Damage Blog

Related terms: DPN

FDA Approves Nucynta ER (tapentadol) Extended-Release Oral Tablets for the Management of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Posted 29 Aug 2012 by Drugs.com

RARITAN, N.J., Aug. 29, 2012 /PRNewswire/ – Janssen Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for Nucynta ER (tapentadol) extended-release tablets, an oral analgesic taken twice daily, for the management of neuropathic pain associated with diabetic peripheral neuropathy (DPN) in adults when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Nucynta ER is the first and only opioid approved by the FDA for neuropathic pain associated with DPN. In addition to this new indication, Nucynta ER is currently approved for the management of moderate to severe chronic pain in adults when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Diabetes affects nearly 26 million people in the United States, and approximately 60 to ... Read more

Related support groups: Nucynta, Diabetic Nerve Damage, Tapentadol

Pain Reported by Nearly Half With Type 2 Diabetes

Posted 14 Aug 2012 by Drugs.com

TUESDAY, Aug. 14 – Nearly 50 percent of patients with type 2 diabetes say they have acute and chronic pain, and about one-quarter suffer from a wide range of symptoms, including nerve damage, fatigue and depression, a new study indicates. As a result, specialized treatment, called palliative care, that focuses on relieving symptoms and improving quality of life should be a normal part of diabetes management, the researchers suggest. "Adults living with type 2 diabetes are suffering from incredibly high rates of pain and non-pain symptoms, at levels similar to patients living with cancer," lead study author Dr. Rebecca Sudore, a staff physician at San Francisco VA Medical Center and associate professor of medicine at the University of California, San Francisco, said in a news release that was released jointly by the medical center, the university and Kaiser Permanente. "Palliative care ... Read more

Related support groups: Diabetes, Type 2, Diabetic Neuropathy, Diabetic Nerve Damage

Sleep Apnea May Be Linked to Nerve Damage in Diabetics

Posted 18 Jun 2012 by Drugs.com

MONDAY, June 18 – Obstructive sleep apnea is associated with nerve damage in people with type 2 diabetes, according to a new study. The severity of this type of nerve damage – called diabetic peripheral neuropathy – is linked with the extent of sleep apnea and the degree of low blood oxygen levels that occur while patients sleep, the researchers found. People with obstructive sleep apnea subconsciously awaken many times a night – even dozens of times an hour – because their airways close, disrupting their breathing. Those with diabetic peripheral neuropathy may have numbness or tingling in their extremities, or damage to their major organs. The study of 234 adults with type 2 diabetes found that sleep apnea was independently associated with diabetic peripheral neuropathy even after the researchers accounted for a number of other possible factors, including obesity, ethnicity, ... Read more

Related support groups: Diabetes, Type 2, Diabetic Neuropathy, Sleep Apnea, Diabetic Nerve Damage

Exercise Appears to Ease Nerve-Damage Pain in Rat Study

Posted 6 Jun 2012 by Drugs.com

WEDNESDAY, June 6 – Exercise helps reduce pain from nerve damage caused by injury, diabetes and other conditions, according to a study involving rats. Researchers found that exercise appears to ease this type of pain – called neuropathic pain – by reducing levels of inflammation-causing substances called cytokines. Neuropathic pain is common but hard to treat. These findings suggest that exercise could provide an effective non-drug treatment for neuropathic pain, according to lead author Yu-Wen Chen, of China Medical University in Taiwan, and colleagues. The study was published in the June issue of the journal Anesthesia & Analgesia. For the study, researchers injured the sciatic nerve in rats and had them do exercise – either swimming or treadmill running – over a few weeks. These rats showed a 30 percent to 50 percent reduction in neuropathic pain, as assessed by their responses ... Read more

Related support groups: Diabetic Neuropathy, Diabetic Nerve Damage

Prediabetes Not to Blame for Nerve Damage: Study

Posted 24 Feb 2012 by Drugs.com

FRIDAY, Feb. 24 – A new study finds that people with prediabetes are no more likely to have a type of nerve damage called small fiber polyneuropathy than healthy people, a finding that contradicts two decades of medical reports. The Mayo Clinic researchers said the results from their five-year study of 550 people suggest that doctors should look for causes other than prediabetes in patients with painful small fiber polyneuropathy. Prediabetes, also called borderline diabetes, is higher than normal blood sugar levels, but not high enough to be considered diabetes. "It is highly unlikely that impaired glucose or associated metabolic derangements cause polyneuropathy, at least not to the high frequency previously reported," lead author and neurologist Dr. Peter Dyck said in a Mayo news release. The study was published in the February issue of the journal Diabetes Care. Diabetic ... Read more

Related support groups: Diabetic Neuropathy, Diabetic Nerve Damage, Pre-Diabetes

Drug Combo May Offer Best Relief for Nerve Pain

Posted 16 Jul 2010 by Drugs.com

TUESDAY, Sept. 29 – People with nerve pain respond better to a combination treatment using the anticonvulsant gabapentin and antidepressant nortriptyline than to treatment with either drug alone, according to Canadian researchers. The study findings suggest that combination treatment could be used to help people who only partially respond to one drug or the other. Nerve, or neuropathic, pain – which affects 2 to 3 percent of the population – is "initiated or caused by a primary lesion or dysfunction in the nervous system," according to a news release from The Lancet, which is publishing the study online Sept. 29. Conditions that cause neuropathic pain include nerve problems in the spine, diabetes-related nerve damage and postherpetic neuralgia (PHN), which is nerve pain caused by the varicella zoster virus that can follow an outbreak of shingles. The study included 56 people with PHN ... Read more

Related support groups: Gabapentin, Neurontin, Neuralgia, Nortriptyline, Diabetic Neuropathy, Persisting Pain, Shingles, Diabetic Nerve Damage, Postherpetic Neuralgia, Pamelor, Gabarone, Aventyl HCl

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