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ICU-Related Depression Often Overlooked, Study Finds
Posted 9 days ago by Drugs.com
TUESDAY, April 8, 2014 – One-third of patients admitted to an intensive care unit develop depression that causes physical symptoms rather than the typical psychological signs, a new study finds. As a result, their condition may go undiagnosed and they may not get needed help, the research suggested. "It's a significant public health issue. We need to pay more attention to preventing and treating the physical rather than psychological symptoms of depression in ICU survivors," said study leader James Jackson, a psychologist and assistant professor of medicine at Vanderbilt University Medical Center in Nashville. The physical signs of depression included weakness, changes in appetite and fatigue, the researchers said. "The physical symptoms of depression are often resistant to standard treatment with antidepressant drugs and we need to determine how best to enhance recovery with a new ... Read more
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Depression May Be Linked to Heart Failure
Posted 13 days ago by Drugs.com
FRIDAY, April 4, 2014 – Depression may increase the risk of heart failure, a new study suggests. Researchers looked at nearly 63,000 people in Norway who underwent physical and mental health assessments. Over 11 years, close to 1,500 of the participants developed heart failure. Compared to people with no symptoms of depression, those with mild symptoms were 5 percent more likely to develop heart failure, and those with moderate to severe symptoms had a 40 percent increased risk. The study was scheduled for presentation Friday at a meeting of the European Society of Cardiology in Stavanger, Norway. "Depressive symptoms increase the chance of developing heart failure and the more severe the symptoms are, the greater the risk," study first author Lise Tuset Gustad, an intensive care nurse at Levanger Hospital in Norway, said in a society news release. "Depressed people have less healthy ... Read more
Related support groups: Depression, Heart Failure, Congestive Heart Failure
Depressed Diabetics May Face Higher Risk of Kidney Disease
Posted 27 Mar 2014 by Drugs.com
THURSDAY, March 27, 2014 – When people with diabetes are depressed, their odds of developing chronic kidney disease nearly double, a new study suggests. Chronic kidney disease, which can lead to kidney failure, is a progressive loss of kidney function over months or years. Diabetes is the most common cause of kidney failure, according to the U.S. National Institute of Diabetes, Digestive and Kidney Diseases. Working with diabetic patients with chronic kidney disease, study author Dr. Margaret Yu, a nephrology fellow at the University of Washington in Seattle, found that many also suffered from depression. She wondered whether the kidney problems were causing depression, or if depression somehow contributed to kidney disease. For the study to be published in the Clinical Journal of the American Society of Nephrology, the researchers looked at almost 4,000 adults with diabetes who were ... Read more
Related support groups: Depression, Diabetes, Type 2, Chronic Kidney Disease
Scientists Spot Another Gene That May Raise Depression Risk
Posted 25 Mar 2014 by Drugs.com
TUESDAY, March 25, 2014 – Scientists report that they have found another gene that might increase a person's risk of developing depression. The effect of variations in this particular gene appears to be small, but scientists hope their discovery will one day provide a new target for drug development. "[For now], further research may identify people who are at risk of depression after life stresses due to specific personality traits and genetic variations," said study author Gyorgy Bagdy, chairman of the department of pharmacodynamics at Semmelweis University in Budapest, Hungary. Experts are still trying to figure out how to improve depression treatments by drawing on a growing understanding of how different genes affect human resilience – the way a person copes with life. Research suggests that 9 percent of American adults suffer from depression, with almost half of that group ... Read more
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More Evidence That Bullying Raises Kids' Suicide Risk
Posted 10 Mar 2014 by Drugs.com
MONDAY, March 10, 2014 – Children and teens involved in bullying – victims and perpetrators alike – are more likely to think about suicide or attempt it. And cyber bullying appears more strongly linked to suicidal thoughts than other forms of bullying, a new research review finds. The findings "establish with more certainty that bullying is related to suicide thoughts and attempts," said study lead author Mitch van Geel, a researcher with the Institute of Education and Child Studies at Leiden University in the Netherlands. "And we establish that these results hold for boys and girls, and older and younger children." Bullying is widespread among children and teens. According to previous studies, almost 50 percent of kids in grades 4 to 12 reported being bullied within the previous month. Nearly one-third said they were bullies themselves. The new results, published March 10 in the ... Read more
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FDA Medwatch Alert: Effexor XR 150 Mg Extended-Release Capsules (Pfizer) and Venlafaxine HCl 150 Mg Extended-Release Capsules (Greenstone): Recall - Possible Presence of Tikosyn Capsules
Posted 9 Mar 2014 by Drugs.com
[Posted 03/07/2014] ISSUE: Pfizer Inc. issued a voluntary recall of one lot of 30-count Effexor XR (venlafaxine HCl) 150 mg extended-release capsules, one lot of 90-count Effexor XR (venlafaxine HCl) 150 mg extended-release capsules, and one lot of 90-count Greenstone LLC-branded Venlafaxine HC1 150 mg extended-release capsules. This action is being taken because of a pharmacist report that one bottle of Pfizer’s Effexor XR contained one capsule of Tikosyn (dofetilide) 0.25mg in addition to the Effexor XR capsules. The use of Tikosyn by an Effexor XR/Venlafaxine HCl patient, where the contraindications and drug-drug interactions with Tikosyn have not been considered by the prescribing physician, could cause serious adverse health consequences that could be fatal. This recall is to the patient level and involves Pfizer lot numbers V130142 and V130140, which both expire in October 2015, ... Read more
Related support groups: Depression, Effexor XR, Venlafaxine
FDA Medwatch Alert: Effexor XR 150 Mg Extended-Release Capsules (Pfizer) and Venlafaxine HCl 150 Mg Extended-Release Capsules (Greenstone): Recall - Possible Presence of Tikosyn Capsules
Posted 7 Mar 2014 by Drugs.com
[Posted 03/07/2014] ISSUE: Pfizer Inc. issued a voluntary recall of one lot of 30-count Effexor XR (venlafaxine HCl) 150 mg extended-release capsules, one lot of 90-count Effexor XR (venlafaxine HCl) 150 mg extended-release capsules, and one lot of 90-count Greenstone LLC-branded Venlafaxine HC1 150 mg extended-release capsules. This action is being taken because of a pharmacist report that one bottle of Pfizer’s Effexor XR contained one capsule of Tikosyn (dofetilide) 0.25mg in addition to the Effexor XR capsules. The use of Tikosyn by an Effexor XR/Venlafaxine HCl patient, where the contraindications and drug-drug interactions with Tikosyn have not been considered by the prescribing physician, could cause serious adverse health consequences that could be fatal. This recall is to the patient level and involves Pfizer lot numbers V130142 and V130140, which both expire in October 2015, ... Read more
Related support groups: Depression, Effexor XR
Hearing Loss Tied to Depression in Study
Posted 6 Mar 2014 by Drugs.com
THURSDAY, March 6, 2014 – Hearing loss is associated with depression among American adults, especially women and those younger than age 70, according to new research. While other studies previously have found the same link, many of them looked only at older adults or at specific regions or ethnicities, and results have been mixed, the researchers pointed out. In the new study, as hearing declined, the percentage of depressed adults increased – from about 5 percent in those who had no hearing problems to more than 11 percent in those who did. "We found a significant association between hearing impairment and moderate to severe depression," said study author Dr. Chuan-Ming Li, a researcher at the U.S. National Institute on Deafness and Other Communication Disorders. "The cause-and-effect relationship is unknown," Li said, citing a need for further studies. The study was published online ... Read more
Related support groups: Depression, Hearing Loss
Too Often, Doctors Miss Suicide's Warning Signs: Study
Posted 27 Feb 2014 by Drugs.com
THURSDAY, Feb. 27, 2014 – Nearly 37,000 Americans kill themselves each year, according to federal statistics. But many of those deaths might have been prevented if doctors had been better at picking up on the warning signs of suicide, a new study suggests. "A national suicide reduction goal may be met if more primary care doctors and specialists receive and use training to identify and treat patients most at risk," study lead author Brian Ahmedani, an assistant scientist in the Center for Health Policy and Health Services Research at Henry Ford Health System in Detroit, said in a statement from the health system. According to the U.S. Centers for Disease Control and Prevention, suicide remains the 10th leading cause of death in the United States and is the leading cause of injury-related death, recently topping deaths tied to car accidents. However, the new study finds that physicians ... Read more
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Kids' Checkups Should Include Cholesterol, Depression Tests, Doctors Say
Posted 24 Feb 2014 by Drugs.com
MONDAY, Feb. 24, 2014 – Doctors should test middle school-age children for high cholesterol and start screening for depression at age 11, according to updated guidelines from a leading group of U.S. pediatricians. Doctors should also test older teens for HIV, the AIDS-causing virus, the revised preventive-care recommendations from the American Academy of Pediatrics say. The new screening schedule provides "the recommended content for a well-child visit," said Dr. Joseph Hagan, co-editor of the guidelines. "Some changes are small, some will get people's attention." The changes attempt to address several pressing health issues affecting U.S. families today. The nation's obesity epidemic means that children are developing high cholesterol levels – a risk factor for heart disease – at earlier ages. And depression is linked to higher risk for teen suicides and murder. "One in five kids ... Read more
Related support groups: Depression, High Cholesterol
Could Thyroid Activity Raise Depression Risk in Seniors?
Posted 20 Feb 2014 by Drugs.com
THURSDAY, Feb. 20, 2014 – Older adults with slightly elevated thyroid activity may be at increased risk for depression, a new study indicates. Researchers analyzed data from more than 1,500 people, average age 70, who were depression-free and had their thyroid activity assessed at the start of the study. Over eight years of follow-up, people with thyroid glands that were more active than average – but still within the normal range – were more likely to develop depression than those with lower levels of thyroid activity within the normal range, the investigators found. "These results provide insight into the powerful effects thyroid activity can have on emotions and mental health," Dr. Marco Medici, of the Erasmus Medical Center in the Netherlands, said in a news release from the Endocrine Society. Hormones produced in the thyroid gland control the rate of many bodily activities. ... Read more
Related support groups: Depression, Hyperthyroidism
Early Treatment for Depression May Be Good for the Heart
Posted 11 Feb 2014 by Drugs.com
TUESDAY, Feb. 11, 2014 – Treating depression in its early stages might help reduce the risk of heart attack and stroke, a new study suggests. Researchers assessed 235 older people diagnosed with depression. The patients were randomly assigned to receive either antidepressants and psychotherapy or standard care determined by their doctor. Patients who had no evidence of heart disease at the study start who received antidepressants and therapy for their depression almost halved their risk of a heart attack or stroke during the eight years of the study, compared with the standard care group, the researchers found. "Ultimately, this line of research could produce a new approach to preventing cardiovascular disease," said study author Jesse Stewart, an associate professor of psychology at Indiana University-Purdue University Indianapolis. Health-care professionals have long known that ... Read more
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Risk of Depression May Rise With Too Much or Too Little Sleep
Posted 6 Feb 2014 by Drugs.com
WEDNESDAY, Feb. 5, 2014 – Too much or too little sleep can increase the risk of depression, according to two new studies. Inappropriate amounts of sleep may activate depression-related genes, researchers report in the Feb. 1 issue of the journal Sleep. One study included more than 1,700 adult twins. Among those who got normal amounts of sleep (seven to nearly nine hours a night), the genetic influence on symptoms of depression was 27 percent versus 53 percent for those who slept only five hours a night, and 49 percent among those who slept 10 hours a night. "Both short and excessively long sleep durations appear to activate genes related to depressive symptoms," lead investigator Dr. Nathaniel Watson, an associate professor of neurology and co-director of the University of Washington Medicine Sleep Center in Seattle, said in a journal news release. Ensuring that patients get optimum ... Read more
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Risk of Depression May Rise With Too Much or Too Little Sleep
Posted 6 Feb 2014 by Drugs.com
WEDNESDAY, Feb. 5, 2014 – Too much or too little sleep can increase the risk of depression, according to two new studies. Inappropriate amounts of sleep may activate depression-related genes, researchers report in the Feb. 1 issue of the journal Sleep. One study included more than 1,700 adult twins. Among those who got normal amounts of sleep (seven to nearly nine hours a night), the genetic influence on symptoms of depression was 27 percent versus 53 percent for those who slept only five hours a night, and 49 percent among those who slept 10 hours a night. "Both short and excessively long sleep durations appear to activate genes related to depressive symptoms," lead investigator Dr. Nathaniel Watson, an associate professor of neurology and co-director of the University of Washington Medicine Sleep Center in Seattle, said in a journal news release. Ensuring that patients get optimum ... Read more
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Primary Care Providers May Balk at Giving Teens Antidepressants
Posted 15 Jan 2014 by Drugs.com
WEDNESDAY, Jan. 15, 2014 – Primary health care providers are reluctant to prescribe antidepressants for their teenaged patients, even in cases of severe depression, a new study suggests. The researchers found that those who were more knowledgeable about depression – and especially those who could consult with an on-site mental health expert – were more likely to prescribe antidepressants for depressed teens. The study included 58 pediatric primary care providers. Most were doctors, but some were nurse practitioners or other professionals. The study participants were given hypothetical situations describing two 15-year-old girls with depression. One girl met the criteria for moderate depression and the other for severe depression, but neither was suicidal. The participants were asked to make an initial treatment recommendation for each of the girls. Only one-quarter of them said they ... Read more
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