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Related terms: Chronic Brain Syndrome, DLB, Memory Loss

Seniors' Worsening Depression May Sometimes Predict Dementia

Posted 1 day 2 hours ago by Drugs.com

FRIDAY, April 29, 2016 – In some cases, worsening symptoms of depression in seniors might point to early dementia, a new study suggests. The Dutch study can't prove cause-and-effect, and certainly not every depressed senior is headed for dementia. But experts said the findings are intriguing. "More research is needed, but the study raises the possibility of an overlap between the pathology of dementia and depression," said Dr. Gisele Wolf-Klein, who reviewed the findings. She directs geriatric education at Northwell Health in New Hyde Park, N.Y. The study was led by Dr. M Arfan Ikram, an epidemiologist at Erasmus University Medical Center in Rotterdam. His team tracked depression symptoms in more than 3,300 adults, aged 55 and older, in the Netherlands for 11 years. The patients were then monitored for signs of dementia for another 10 years. During that follow-up, 434 of the ... Read more

Related support groups: Depression, Major Depressive Disorder, Dementia, Alzheimer's Disease, Dysthymia, Mild Cognitive Impairment, Neurotic Depression, Arteriosclerotic Dementia, Depressive Psychosis, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Trouble With Sense of Direction May Be Linked to Early Alzheimer's: Study

Posted 4 days ago by Drugs.com

TUESDAY, April 26, 2016 – Difficulty remembering how to get around in new surroundings may be an extremely early sign of Alzheimer's, a small study suggests. The findings, if borne out in future research, might help doctors diagnose Alzheimer's long before someone shows obvious memory problems, said researchers from Washington University in St. Louis. The study included 16 people with symptoms of early stage Alzheimer's and 13 outwardly normal people with signs of preclinical Alzheimer's in fluid from around their brain and spinal cord (cerebrospinal fluid). A control group of 42 healthy people without the cerebrospinal markers was also involved. Preclinical Alzheimer's disease refers to brain changes that occur before symptoms develop that lead to its diagnosis. The study participants were tested on their ability to remember how to navigate a virtual maze on a computer with a series ... Read more

Related support groups: Dementia, Alzheimer's Disease

Do Genes That Protect Against Dementia Guard Against Chronic Diseases?

Posted 9 days ago by Drugs.com

THURSDAY, April 21, 2016 – Healthy elderly people have a higher-than-normal number of genetic variants that protect against mental decline, a new study reports. The findings suggest a possible link between long-term brain health and protection from chronic diseases such as cancer, heart disease and diabetes, the researchers said. "For many decades, we have searched for the genetic causes of disease in sick individuals," said Eric Schadt, founding director of the Icahn Institute for Genomics and Multiscale Biology at Mount Sinai in New York City. This study "presents an attractive alternative by studying those who are well in order to uncover the solutions nature has provided to protect us against disease," said Schadt, who was not involved with the study. The researchers – from the Scripps Translational Science Institute, in La Jolla, Calif. – analyzed the genetic makeup of 511 ... Read more

Related support groups: Diabetes, Type 2, Cancer, Dementia, Alzheimer's Disease, Ischemic Heart Disease

HIV Patients Now Living Long Enough to Develop Alzheimer's

Posted 11 days ago by Drugs.com

TUESDAY, April 19, 2016 – The first case of Alzheimer's disease diagnosed in a person with HIV highlights the fact that long-time HIV survivors are starting to reach ages where their risk for Alzheimer's increases, researchers report. The 71-year-old man was diagnosed after a medical scan revealed amyloid protein clumps in his brain. Until now, it was believed that HIV-related inflammation in the brain might prevent the formation of such clumps and thereby protect these people from Alzheimer's. "This patient may be a sentinel case that disputes what we thought we knew about dementia in HIV-positive individuals," said study author Dr. R. Scott Turner. He is head of the Memory Disorders Program at Georgetown University Medical Center in Washington, D.C. The case also suggests that some older people with HIV and dementia may be misdiagnosed with HIV-associated brain disorders, but ... Read more

Related support groups: HIV Infection, Dementia, Alzheimer's Disease, Pre-Exposure Prophylaxis, Mild Cognitive Impairment, Arteriosclerotic Dementia, Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia

Alzheimer's Can Steal Ability to Know Loved Ones' Faces

Posted 17 days ago by Drugs.com

WEDNESDAY, April 13, 2016 – A new study sheds light on what is often called one of the cruelest effects of Alzheimer's disease – the patient's inability to recognize loved ones. Researchers report that along with causing memory loss, Alzheimer's also seems to affect people's visual perception – specifically their ability to recognize faces. The investigators tested a group of seniors with Alzheimer's, and a "control" group without the brain disease, to see how well they could perceive faces and cars in photos. The pictures were shown either upright or upside down. "The results for people with Alzheimer's were similar to those in the control group in terms of answer accuracy and the time to process the upside-down faces and cars," study author Sven Joubert, from the University of Montreal, said in a school news release. "To perform these tasks, the brain must perform a local analysis ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Diagnosis and Investigation, Visual Defect/Disturbance, Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia

Severe Depression Linked to Dementia in Seniors

Posted 18 days ago by Drugs.com

TUESDAY, April 12, 2016 – Major and worsening depression may significantly increase seniors' risk of dementia, a new study suggests. The research included close to 2,500 people in their 70s who did not have any signs of dementia at the start of the study. The participants were monitored for five years for symptoms of depression, and then for six years for signs of dementia. Dementia developed in just over 21 percent of participants with serious and escalating symptoms of depression, compared to about 12 percent of those with consistently minimal symptoms of depression, the findings showed. "Our results raise the possibility that older adults' cognitive [mental] health could be improved with interventions to reduce depressive symptoms, such as psychotherapy or other behavioral interventions, or medications," said study author Allison Kaup. She is an assistant professor in the department ... Read more

Related support groups: Depression, Major Depressive Disorder, Dementia, Alzheimer's Disease, Dysthymia, Mild Cognitive Impairment, Lewy Body Dementia

Is Seniors' Dental Health Tied to Mental Health?

Posted 1 Apr 2016 by Drugs.com

FRIDAY, April 1, 2016 – There seems to be a link between poor oral health and age-related mental decline, researchers say. However, the researchers emphasized there is not enough evidence to prove a direct link between oral health and thinking ("cognitive") abilities. In a new report, investigators reviewed studies on oral health and cognition published between 1993 and 2013. Some of the studies found that oral health indicators – such as the number of teeth, the number of cavities and the presence of gum disease – was associated with a higher risk of mental decline or dementia, while other studies did not find any association. The study authors also noted that some of the findings based on the number of teeth or cavities were conflicting. The new review was published in the April 1 issue of the Journal of the American Geriatrics Society. Overall, "clinical evidence suggests that the ... Read more

Related support groups: Oral and Dental Conditions, Xerostomia, Dementia, Toothache, Alzheimer's Disease, Gingivitis, Mild Cognitive Impairment, Periodontitis, Arteriosclerotic Dementia, Stomatitis, Prevention of Dental Caries, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Scientists Reduce Alzheimer's-Linked Brain Plaques in Mice

Posted 1 Apr 2016 by Drugs.com

THURSDAY, March 31, 2016 – Scientists working with mice report preliminary progress in efforts to eliminate brain-clogging proteins linked to Alzheimer's disease. By tweaking genes in the brains of mice, researchers say they reduced levels of a substance called beta amyloid that's closely tied to Alzheimer's. There's no guarantee the findings will be relevant to people with Alzheimer's disease because results of animal studies often aren't replicated in humans, experts say. Still, "we can now target amyloids from a different angle," said study co-author Guojun Bu, a neuroscientist and professor of medicine at the Mayo Clinic in Jacksonville, Fla. The approach "can be explored for Alzheimer's disease prevention and therapy," he added. Clumps of beta-amyloid proteins, known as plaque, are believed to disrupt brain functioning in people with Alzheimer's disease, the most common form of ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Diagnosis and Investigation, Lewy Body Dementia

Caregivers Often Give Up Necessities to Cover Alzheimer's Costs

Posted 30 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – Caring for someone with Alzheimer's disease means caregivers often skimp on their own food and medical care, and even sell their belongings to support their loved one, a new report released Wednesday shows. The centerpiece of the Alzheimer's Association's annual report was a nationwide survey detailing the heavy financial and emotional toll caregivers endure. According to the survey, caregivers were 28 percent more likely to eat less or go hungry, and one-fifth cut back on doctor visits. Nearly half of them cut back on their own expenses to afford dementia-related care. And more than one-third reduced their hours at work or quit their job to care for a loved one, losing an average of $15,000 in income. "Care contributors are making enormous personal and financial sacrifices, and these sacrifices are jeopardizing their own and their family's financial ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Could Less Time Spent Online Signal Early Alzheimer's?

Posted 28 Mar 2016 by Drugs.com

MONDAY, March 28, 2016 – Spending less time on their home computer may be a sign that seniors have early stage Alzheimer's disease, researchers suggest. Computer use requires multiple brain functions, including attention, planning and memory. While there may be various reasons why an elderly person spends less time online, the researchers suggest that diminishing mental capabilities might be one of them. Their study included men and women aged 65 and older who had no signs of dementia or other thinking and memory problems. Participants underwent MRI scans of the hippocampus, an area of the brain crucial to memory. They also had their technology time monitored. A decrease in hippocampus volume is a well-known sign of Alzheimer's disease, the researchers explained. The study found that an additional hour of daily home computer use was associated with a 0.025 percent larger hippocampus ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Simple Steps Can Ease Care of Loved One With Alzheimer's

Posted 28 Mar 2016 by Drugs.com

FRIDAY, March 25, 2016 – As Alzheimer's disease progresses, patients find that simple tasks become difficult or impossible, but caregivers can help them maintain a sense of independence and dignity, a doctor says. Create a routine that makes days more predictable and schedule the most challenging tasks – such as bathing or medical appointments – at a time of day when your loved one is typically most calm, advised Dr. Ronald Petersen, a Mayo Clinic neurologist. Adapt to your loved one's needs. If he or she insists on wearing the same clothes every day, for instance, consider buying a few identical outfits. Limiting choices will make it easier for the person to decide. Instead of a closet full of clothes, offer a choice of two outfits and do away with belts or accessories that he or she is likely to put on incorrectly. Expect things to take longer than they once did. This will help you ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Exercise May Keep Your Brain 10 Years Younger, Study Suggests

Posted 24 Mar 2016 by Drugs.com

WEDNESDAY, March 23, 2016 – Older adults who exercise regularly could buy an extra decade of good brain functioning, a new study suggests. The study found that seniors who got moderate to intense exercise retained more of their mental skills over the next five years, versus older adults who got light exercise or none at all. On average, those less-active seniors showed an extra 10 years of "brain aging," the researchers said. The findings do not prove that exercise itself slows brain aging, cautioned senior researcher Dr. Clinton Wright, a neurologist at the University of Miami Miller School of Medicine. It's possible, he said, that there are other reasons why active older adults stayed mentally sharper. The researchers accounted for some of those other explanations – including people's education levels, smoking habits and health conditions such as high blood pressure and diabetes. ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia

Want to Keep an Aging Brain Sharp? Try the Stairs

Posted 15 Mar 2016 by Drugs.com

TUESDAY, March 15, 2016 – Aging Americans looking to maintain a healthy brain may want to switch from elevators to stairs, new research suggests. Fitness seemed key to sharper minds as people got older, a Canadian study found, as was more time spent reading and studying. The findings show "that education and physical activity affect the difference between a physiological prediction of age and chronological age, and that people can actively do something to help their brains stay young," said lead investigator Jason Steffener, a scientist at Concordia University in Montreal. "This is encouraging because it demonstrates that a simple thing like climbing stairs has great potential as an intervention tool to promote brain health," Steffener said in a university news release. The researchers used MRI scans to assess the physical brain health of 331 healthy adults, aged 19 to 79. Those who ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Research Offers Clues to Dementia With Language Loss

Posted 14 Mar 2016 by Drugs.com

SUNDAY, March 13, 2016 – Toxic buildup of a protein in the brain's language centers may help drive a rare form of dementia that causes people to lose their ability to use language, a new study finds. Researchers at Northwestern University in Chicago used high-tech imaging to track the buildup of amyloid protein in the brains of people with the language-loss dementia, called primary progressive aphasia (PPA). They compared those findings to amyloid buildup in the brains of people with memory loss related to Alzheimer's disease. Both illnesses are strongly linked to an accumulation of amyloid protein in the brain, the researchers noted. Patients with PPA had more amyloid in the left side of the brain, where language processing occurs, than on the right side of the brain, the researchers reported recently in the Annals of Neurology. On the other hand, patients with Alzheimer's-related ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Computer Use May Help Deflect Seniors' Memory Problems

Posted 3 Mar 2016 by Drugs.com

THURSDAY, March 3, 2016 – Seniors who use their computers as little as once a week may help ward off age-related declines in memory and thinking, new research suggests. The study found that those who did use a computer showed a 42 percent lower risk of developing mild cognitive impairment (MCI), a precursor to dementia. What isn't yet clear is exactly how computer use might help save memory and thinking abilities. "We did not investigate mechanisms that might underlie the association between mentally stimulating activities such as computer use and the risk of incident MCI," said study author Janina Krell-Roesch, a research fellow at the Mayo Clinic in Scottsdale, Ariz. "Therefore, we can only speculate why computer use might be of help." Seniors who reach for their keyboards may simply be more likely to adhere to a generally healthier and more "disciplined" lifestyle, Krell-Roesch ... Read more

Related support groups: Dementia, Mild Cognitive Impairment

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Related Condition Support Groups

Alzheimer's Disease, Mild Cognitive Impairment, Lewy Body Dementia, Arteriosclerotic Dementia, Central Nervous System Disorders

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Haldol, haloperidol, Haldol Decanoate, Hydergine, Cognex, tacrine, Gerimal, Hydergine LC, ergoloid mesylates