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FDA Approves Edarbyclor (azilsartan medoxomil and chlorthalidone) for the Treatment of Hypertension
Posted 20 Dec 2011 by Drugs.com
DEERFIELD, Ill. and OSAKA, Japan, Dec. 20, 2011 /PRNewswire/ – Takeda Pharmaceutical Company Limited (Takeda) and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc., announced today that the U.S. Food and Drug Administration (FDA) approved Edarbyclor (azilsartan medoxomil and chlorthalidone) for the treatment of hypertension to lower blood pressure in adults. Edarbyclor is the only fixed-dose therapy in the U.S. to combine an angiotensin II receptor blocker (ARB) with the diuretic chlorthalidone in a once-daily, single tablet. The recommended starting dose of Edarbyclor is 40/12.5 mg and the maximum dose is 40/25 mg. The two medications in Edarbyclor work to help lower blood pressure in patients with hypertension. Azilsartan medoxomil, marketed as Edarbi in the U.S., reduces blood pressure by blocking the action of angiotensin II, a vasopressor hormone that ... Read more
Related support groups: Hypertension, Chlorthalidone, Azilsartan medoxomil
Treating High Blood Pressure May Add Years to Life
Posted 20 Dec 2011 by Drugs.com
TUESDAY, Dec. 20 – People suffering from high blood pressure, or hypertension, who keep their blood pressure levels under control may add years to their life, a new study suggests. In fact, those in the study who took medicine to lower their blood pressure for more than four years reduced their risk of dying from cardiovascular disease over a 20-year period, the researchers found. "For the first time, we prove that treating high blood pressure prolongs life," said lead researcher Dr. John Kostis, a professor of medicine & pharmacology at UMDNJ-Robert Wood Johnson Medical School in New Brunswick, N.J. "If you take your medications for a month, you live an extra day," he said. "One day benefit from a month of treatment sounds small, but if you start treatment at 40, for example, then you live a couple of extra years." Although the antihypertensive diuretic chlorthalidone was used in the ... Read more
Related support groups: High Blood Pressure, Hypertension, Chlorthalidone, Hygroton, Thalitone
Accidental Medication Poisonings in Kids on the Rise
Posted 16 Sep 2011 by Drugs.com
FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more
Related support groups: Suboxone, Xanax, Methadone, Oxycodone, Percocet, OxyContin, Hydrocodone, Vicodin, Morphine, Norco, Fentanyl, Klonopin, Lortab, Lisinopril, Subutex
Generics As Good As Costly Blood Pressure Meds, Study Finds
Posted 15 Aug 2010 by Drugs.com
FRIDAY, Aug. 13 – Costly, brand-name blood pressure-lowering drugs are no better at preventing cardiovascular disease than older, generic diuretics, reveals long-term data from a large study. It included more than 33,000 patients with high blood pressure who were randomly selected to take either a diuretic (chlorthalidone) or one of two newer drugs – a calcium blocker (amlodipine) or an ACE inhibitor (lisinopril). Data from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) released in 2002 showed that after four to eight years of follow-up, the diuretic was better than the calcium blocker in preventing heart failure and better than the ACE inhibitor in preventing stroke, heart failure and overall cardiovascular disease. Differences between the drugs narrowed after eight to 13 years of follow-up, the findings show. However, the diuretic was still ... Read more
Related support groups: High Blood Pressure, Lisinopril, Hypertension, Amlodipine, Norvasc, Zestril, Chlorthalidone, Prinivil, Hygroton, Thalitone
Statins, Painkillers May Upset PSA Test Results
Posted 7 Aug 2010 by Drugs.com
FRIDAY, Aug. 6 – Some of the most widely prescribed drugs in the United States may skew results of prostate cancer screening tests, possibly causing errors in diagnoses, a new study finds. A prostate cancer diagnosis is typically based on an elevated PSA (prostate-specific antigen)level, but new research shows that common drugs, including cholesterol-lowering statins and certain painkillers, may lower PSA levels. "Our study reveals that men regularly consuming NSAIDs [non-steroidal anti-inflammatory drugs], statins, and thiazide diuretics may have lower serum PSA levels compared to men who are not taking these medications," said Dr. Steven L. Chang, lead author of a paper published online Aug. 2 in the Journal of Clinical Oncology. "This could be a confounder when you're trying to screen for prostate cancer," added Dr. Lionel L. Bañez, assistant professor of urologic surgery at Duke ... Read more
Related support groups: Ibuprofen, Simvastatin, Naproxen, Lipitor, Crestor, Meloxicam, Advil, Hydrochlorothiazide, Diclofenac, Prostate Cancer, Mobic, Aleve, Pravastatin, Motrin, Zocor
Diet, Meds and Smoking Linked to Eye Disease Risks
Posted 14 Jun 2010 by Drugs.com
MONDAY, June 14 – A healthy diet helps guard against cataracts, while certain medications raise the risks of this common cause of vision loss, two new studies suggest. And a third study finds that smoking increases the risk of age-related macular degeneration, another disease that robs people of their sight. The first study found that women who eat foods that contain high levels of a variety of vitamins and minerals may be less likely to develop nuclear cataract, which is the most common type of age-related cataract in the United States. The study is published in the June issue of the Archives of Ophthalmology. The researchers looked at 1,808 women in Iowa, Oregon and Wisconsin who took part in a study about age-related eye disease. Overall, 736 (41 percent) of the women had either nuclear cataracts evident from lens photographs or reported having undergone cataract extraction. ... Read more
Related support groups: Smoking, Amitriptyline, Naproxen, Elavil, Cipro, Levaquin, Hydrochlorothiazide, Nortriptyline, Ciprofloxacin, Aleve, Avelox, Doxepin, Cataract, Pamelor, Imipramine
Diuretics Still Best Treatment for High Blood Pressure
Posted 1 Dec 2009 by Drugs.com
WEDNESDAY, Nov. 18 – Tried-and-true diuretics maintain their status as the best first-line treatment in older men and women with high blood pressure, new research concludes. The thiazide-type diuretic chlorthalidone outshone three other treatments – a calcium channel blocker, an ACE inhibitor and an alpha-receptor blocker – in most areas, especially in lowering the incidence of stroke and heart failure, according to the most current data from a large ongoing study known as ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). "We believe thiazide-type diuretics should still be preferred," said study investigator Dr. William Cushman, professor and chief of preventive medicine at the Veterans Affairs Medical Center in Memphis, Tenn., at a news conference on the findings Wednesday at the annual meeting of the American Heart Association (AHA) in Orlando, ... Read more
Related support groups: High Blood Pressure, Hypertension, Hydrochlorothiazide, Chlorthalidone, Indapamide, Bendroflumethiazide, Lozol, Zaroxolyn, Metolazone, HydroDIURIL, Diuril, Naturetin, Hygroton, Polythiazide, Chlorothiazide
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