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Celiac Disease Blog

Includes: Celiac disease, sprue, Celiac sprue, Gluten intolerance, Gluten-sensitive enteropathy, Nontropical sprue, Sprue

Celiac Disease in Women Linked to Depression Risk

Posted 4 Jan 2012 by Drugs.com

WEDNESDAY, Jan. 4 – New research shows that women with celiac disease face a higher risk for also suffering from depression and so-called "disordered eating," regardless of whether they stick to a gluten-free diet. "We found that most [study] participants frequently adhered to a gluten-free diet, and this greater compliance with diet was related to increased vitality, lower stress, decreased depressive symptoms and greater overall emotional health," study co-author Josh Smyth, a professor of bio-behavioral health and medicine at Penn State University, said in a university news release. "However, even those people who were managing their illness very well reported higher rates of stress, depression and a range of issues clustered around body image, weight and shape when compared to the general population," he added. The study results appear online and in an upcoming issue of Chronic ... Read more

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Some 'Gluten-Free' Beers Really Aren't: Study

Posted 28 Dec 2011 by Drugs.com

WEDNESDAY, Dec. 28 – Regular beer and even some brands of beer labeled "low-gluten" contain high levels of gluten and could cause problems for people with celiac disease, a new study says. Beer is made using barely, which contains a form of gluten called hordein. However, some beer companies contend that the brewing process eliminates gluten or reduces it to very low levels, according to a release from the Journal of Proteome Research, where the new study appears. Because existing tests for detecting gluten in malted products are not very accurate, the research team developed a new test that's highly accurate for hordein. They used this test to analyze 60 commercial beers and found that many of the regular brands contained significant levels of hordein. Eight brands labeled "gluten-free" did not contain hordein. However, the researchers were surprised to discover that two of the brands ... Read more

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Gluten in Cosmetics Threaten Those With Celiac Disease

Posted 1 Nov 2011 by Drugs.com

TUESDAY, Nov. 1 – People with celiac disease may unknowingly be exposed to gluten in lip, facial or body products, a new study suggests. Gluten – a protein found in wheat, rye and barley – damages the intestines of people with celiac disease. George Washington University researchers looked at products from the top 10 cosmetic companies in the United States and found a lack of information about ingredients in the products. Only two of the companies offered detailed ingredient information, and none of the companies offered gluten-free products, the researchers found. The study findings were slated for release Monday at the annual scientific meeting of the American College of Gastroenterology in Washington, D.C. "The findings are alarming because gluten-containing cosmetics can be inadvertently obtained by the consumer and use of these products can result in an exacerbation of celiac ... Read more

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Celiac Disease on the Rise in U.S.

Posted 19 Aug 2011 by Drugs.com

FRIDAY, Aug. 19 – Complaints of celiac disease are on the rise in the United States, with more and more people growing ill from exposure to products containing gluten. Nearly five times as many people have celiac disease today than did during the 1950s, according to one recent study. Another report found that the rate of celiac disease has doubled every 15 years since 1974 and is now believed to affect one in every 133 U.S. residents. "It's quite widespread," said Dr. Alessio Fasano, director of the Center for Celiac Research and the Mucosal Biology Research Center at the University of Maryland School of Medicine. "We thought there were regional differences in the past, but now we know it's everywhere." That increased incidence rate has left researchers scrambling to figure out why more people are developing the chronic digestive disorder. Doctors still can't explain the trend, but ... Read more

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More People May Benefit From Going Gluten-Free

Posted 9 May 2011 by Drugs.com

SUNDAY, May 8 – People at risk for celiac disease ought to be screened for the disorder, even if they show no symptoms, a new study suggests. Celiac disease is a disorder that causes digestive problems in the small intestine when the person consumes gluten, a protein found in wheat, rye and barley. The number of U.S. residents with the disease has grown rapidly in recent decades, but, according to the study authors, an estimated 2 million people have the disease but do not know it. For the study, researchers screened 3,031 healthy people who were related to someone with celiac disease, but had no symptoms themselves, and selected 40 people who tested positive for antibodies specific to celiac disease. By random selection, members of that group were either put on a gluten-free diet or told to continue with their normal diet, containing gluten. People on a gluten-free diet reported ... Read more

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Kids' Birth Month Seems to Be Linked to Celiac Disease: Study

Posted 9 May 2011 by Drugs.com

SUNDAY, May 8 – Celiac disease is more common among children born in the spring and summer months, according to a new study from the Massachusetts General Hospital for Children. The findings suggest that the higher incidence of this autoimmune disease may be related to a combination of seasonal and environmental factors. Celiac disease is a digestive disorder triggered by consuming the protein gluten, which is primarily found in bread and other foods containing wheat, barley or rye. It can damage the small intestine and make it difficult to absorb certain nutrients, causing problems ranging from abdominal pain to nerve damage. Examining data on 382 Massachusetts children diagnosed with celiac disease at between 11 months and 19 years of age, researchers found that in the 15- to 19-year-old set, birth season appeared to make no difference. But among 317 children younger than 15 years of ... Read more

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Mouse Study Suggests New Clues to Celiac Disease

Posted 10 Feb 2011 by Drugs.com

WEDNESDAY, Feb. 9 – A key discovery into how celiac disease develops may pave the way toward preventing this painful digestive disorder in those most at risk, a new animal study suggests. Using mice, scientists at the University of Chicago have identified a biochemical interaction that may trigger an autoimmune reaction in the intestines of genetically susceptible people. Specifically, the researchers found that retinoic acid, a form of vitamin A, seems to work together with high levels of a pro-inflammatory substance known as interleukin-15 (IL-15) to break the body's tolerance to gluten, a protein found in wheat, barley and rye. "This is the first time that we actually show how inducing a specific dysregulation in the intestines can lead to losing tolerance to a food antigen, and in particular to gluten," said study author Dr. Bana Jabri, co-director of the university's Digestive ... Read more

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Celiac and Crohn's Disease May Share Genetic Risk Factors

Posted 28 Jan 2011 by Drugs.com

THURSDAY, Jan. 27 – Celiac disease and Crohn's disease share several genetic risk factors, a new study finds. Celiac disease, which makes it hard to absorb nutrients properly, is an inherited autoimmune disease in which the lining of the small intestine is damaged by gluten and other protein found in wheat and some other grains. Crohn's disease is a form of inflammatory bowel disease. An international team of researchers conducted a meta-analysis of genome-wide data for the conditions, both considered inflammatory diseases of the gastrointestinal tract. The causes of the diseases are only partly understood, although it is known that genetic and environmental factors are involved. Previous research has shown that people with celiac disease have an increased risk of developing Crohn's disease, which suggested that the two conditions would share genetic risk factors. The scientists in ... Read more

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Celiac Disease Seems to Be on the Rise, Mainly in Elderly: Study

Posted 27 Sep 2010 by Drugs.com

MONDAY, Sept. 27 – The autoimmune disorder known as celiac disease appears to be on the rise, particularly among elderly Americans, new research suggests. Researchers from the United States and Italy uncovered evidence that overall incidence rates of the disease – marked by an intolerance to the protein gluten that is found in wheat, barley and rye – have been doubling every 15 years since 1974. The findings are reported in the Sept. 27 online edition of Annals of Medicine by lead author Dr. Carlo Catassi, of the Universita Politecnica delle Marche in Ancona, Italy, who also serves as co-director of the University of Maryland School of Medicine Center for Celiac Research. The study authors said it's not clear what causes a person to develop the disease. Genetics seem to play a role, and some people are born with it. But, genetic predisposition doesn't always translate into actual ... Read more

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Study Points to Molecular Origins of Celiac Disease

Posted 21 Jul 2010 by Drugs.com

WEDNESDAY, July 21 – Scientists believe they've identified the molecular triggers of celiac disease, a finding they say could lead to the first drugs to tame the chronic, painful gut disorder. People with celiac disease are intolerant to the protein gluten, which is found in wheat, barley and rye. Consuming these foods triggers an immune reaction that damages the lining of the small intestine, which can prevent the body from absorbing essential vitamins and nutrients. Currently, the only treatment for celiac disease is adoption of a gluten-free diet, which means avoiding many types of bread, pasta, cereal and other foods. But gluten contamination in many foods makes it difficult to avoid and leads to long-lasting intestinal damage in some patients, said study senior author Robert Anderson, head of the celiac disease research laboratory at the Walter and Eliza Hall Institute of Medical ... Read more

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C-Sections May Raise Celiac Disease Risk in Offspring

Posted 18 May 2010 by Drugs.com

TUESDAY, May 18 – Children born by cesarean section may be more likely to develop celiac disease, a chronic digestive disorder, than children born vaginally, new research finds. Researchers analyzed data on almost 2,000 children seen at gastrointestinal outpatient clinics for celiac disease, Crohn's disease, ulcerative colitis and other gastrointestinal diseases, and compared their rates of C-section vs. vaginal delivery to children who had not been diagnosed with any gastrointestinal conditions. Compared to children born vaginally, children delivered by C-section were 80 percent more likely to develop celiac disease. "We did not find any association with the inflammatory bowel diseases, Crohn's disease and ulcerative colitis," said lead study author Dr. Mathias Hornef of Hannover Medical School in Germany. "We did see a moderate but significant association with celiac disease." People ... Read more

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Celiac Disease May Raise Risk of Dying

Posted 2 Feb 2010 by Drugs.com

TUESDAY, Sept. 15 – People with milder symptoms of celiac disease face a slightly higher risk of dying than other people, a new study finds. Cancer and heart disease were the main causes of death in the patients studied, and the risk was higher in people who had had small-intestinal biopsies in childhood, the researchers found. Celiac disease affects about 1 percent of people in the Western world, the researchers said, and it is triggered by exposure to gluten, a protein found in barley, wheat and rye. It frequently causes diarrhea and weight loss. According to the study, which appears in the Sept. 16 issue of the Journal of the American Medical Association, celiac disease is thought to be connected to higher risk of disease, but less is known about "nonspecific small-intestinal inflammation without villous atrophy," a kind abnormality. Swedish researchers found the risk of death ... Read more

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Celiac Disease Making Inroads in U.S.

Posted 1 Jul 2009 by Drugs.com

WEDNESDAY, July 1 – Celiac disease, a serious digestive system disorder, has become far more common in recent years, a new Mayo Clinic study has found. According to a report in the July issue of Gastroenterology, the disease is four times more prevalent in the United States today than in the 1950s. In addition, the researchers found that the death rate was four times higher during the 45 years of the study among people who had the disease but did not know it than it was among those who did not have celiac disease. "Celiac disease has become much more common in the last 50 years, and we don't know why," said Dr. Joseph Murray, a Mayo Clinic gastroenterologist who led the study. "It now affects about 1 in 100 people." Celiac disease is caused by an intolerance to gluten in wheat, barley and rye. An autoimmune reaction damages the small intestine and can cause severe diarrhea, abdominal ... Read more

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Health Tip: Symptoms of Celiac Disease in Adults

Posted 17 Apr 2009 by Drugs.com

-- Celiac disease makes your body intolerant to a protein called gluten, which is found in foods including wheat, rye and barley products. It can also be found in some vitamins, lip balms and medications. According to the National Digestive Diseases Information Clearinghouse, these symptoms may be warning signs of celiac disease in adults: Digestive problems including chronic diarrhea, abdominal bloating and pain. Digestive symptoms, however, are less likely to affect adults than children. Feeling tired, anxious or depressed. Arthritis or osteoporosis. Unexplained anemia. Feelings of numbness or tingling in the feet or hands. Seizures. Irregular menstrual periods, multiple miscarriages or infertility. Canker sores. An itchy skin rash. Read more

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