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Cancer Doctors Still Not Great With Patients' Pain

Posted 17 Nov 2011 by Drugs.com

THURSDAY, Nov. 17 – Oncologists think they are good at managing cancer patients' pain, but a new survey shows otherwise. In response to two hypothetical vignettes describing a cancer patient who was suffering from pain, the majority of oncologists offered up a treatment plan that pain specialists would consider "unacceptable." "There are serious deficiencies in oncologists' knowledge of cancer pain management," said study author Brenda Breuer, director of epidemiologic research in the department of pain medicine and palliative care at Beth Israel Medical Center in New York City. The study appears in the Nov. 14 issue of the Journal of Clinical Oncology. Depending on the type of cancer and how advanced it is, anywhere from 14 percent to 100 percent of cancer patients experience pain, according to background information in the study. In recent years, there's been a growing understanding ... Read more

Related support groups: Pain, Cancer, Breakthrough Pain

Lazanda Approved for Cancer Pain

Posted 5 Jul 2011 by Drugs.com

FRIDAY, July 1 – Lazanda (fentanyl) nasal spray has been approved by the U.S. Food and Drug Administration to treat breakthrough pain in adults with cancer who are already receiving opioid therapy, drug maker Archimedes Pharma said. Breakthrough pain occurs as an intense, unpredictable burst among people who are already receiving therapy for chronic pain. Lazanda is the first nasal spray containing the commonly prescribed opioid painkiller fentanyl, the company said in a news release. Lazanda is available in five European countries under the brand name PecFent. Lazanda will be prescribed under a Risk Evaluation and Mitigation Strategy (REMS) program to minimize instances of abuse and addiction, the drug maker said. The program requires pharmacies, distributors and doctors who prescribe the medication to enroll. The drug's safety and effectiveness were established in clinical studies ... Read more

Related support groups: Fentanyl, Breakthrough Pain, Duragesic, Actiq, Fentora, Duragesic-100, Duragesic-25, Duragesic-50, Sublimaze, Duragesic-12, Abstral, Duragesic-75, Ionsys, Onsolis

FDA Approves Lazanda - First Fentanyl Nasal Spray - for the Management of Breakthrough Pain in Cancer Patients

Posted 30 Jun 2011 by Drugs.com

READING, England and BEDMINSTER, N.J., June 30, 2011 /PRNewswire/ – Archimedes Pharma Ltd., and its subsidiary, Archimedes Pharma U.S. Inc., today announced that the U.S. Food and Drug Administration (FDA) has approved Lazanda (fentanyl) nasal spray for the management of breakthrough pain in cancer patients 18 years of age and older who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain. Lazanda marks the first FDA product approval for Archimedes Pharma. Lazanda is marketed as PecFent (fentanyl pectin nasal spray) in Europe, where it is presently available in five countries. "Lazanda is an important new option for patients with cancer who experience excruciating breakthrough pain," says Jeffrey H. Buchalter, chief executive officer of Archimedes Pharma. "Lazanda, which uses our patented PecSys® drug delivery system, is designed to ... Read more

Related support groups: Pain, Fentanyl, Breakthrough Pain

Study Finds Third of Cancer Patients on Opioids Are Confused

Posted 3 Mar 2011 by Drugs.com

THURSDAY, March 3 – About a third of cancer patients taking opioid painkillers experience cognitive problems such as confusion, disorientation and forgetfulness, a new study finds. Research analyzing 1,915 cancer patients from 17 health-care centers around Europe indicated that 32.9 percent on high-strength opioid drugs such as morphine scored lower on observer-rated mental tests measuring orientation to time and place, attention and word recall, among other skills. Patients with lung cancer were nearly 50 percent more likely to experience cognitive problems, which researchers attributed to the symptom load involved in their diagnosis. But study author Geana P. Kurita cautioned that the association between opioid use and poor mental function does not prove that painkillers cause the problem. "The design allows us to analyze the potential factors that can interfere with cognitive ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Percocet, Hydrocodone, Cancer, OxyContin, Vicodin, Morphine, Norco, Fentanyl, Lortab, Codeine, Opana, Subutex, Dilaudid, Opana ER, Breakthrough Pain, Nucynta, Roxicodone

FDA Approval for Abstral (Fentanyl) Sublingual Tablets

Posted 11 Jan 2011 by Drugs.com

Uppsala, January 10, 2011 - Orexo AB announces today that its partner ProStrakan Group plc has received approval from the US Food and Drug Administration (FDA) for Abstral. Abstral is licensed for the treatment of breakthrough pain in cancer patients, 18 years of age and older, who are already receiving, and are tolerant to, opioid analgesics for their underlying persistent cancer pain. "This is an important step for patients with cancer pain to have options for the treatment of their breakthrough pain," said John Jenkins, M.D., director of FDA's Office of New Drugs in the Center for Drug Evaluation and Research. ProStrakan expects to launch Abstral in the US during Q1 2011. Launch preparations are at an advanced stage and sales teams have already completed a significant level of training. Abstral will be the only fast-acting sublingual tablet for breakthrough cancer pain on the US ... Read more

Related support groups: Fentanyl, Breakthrough Pain

Scientists Discover Substance That Causes Pain

Posted 28 Apr 2010 by Drugs.com

WEDNESDAY, April 28 – The human body produces a substance similar to capsaicin – which makes chili peppers hot – at sites of pain, and blocking production of this substance can ease pain, a new study shows. The findings may lead to the development of non-addictive painkillers, according to the researchers at the University of Texas Health Science Center in San Antonio. In work with mice, the scientists found that a family of fatty acids called oxidized linoleic acid metabolites (OLAMs) play an important role in the biology of pain. "This is a major breakthrough in understanding the mechanisms of pain and how to more effectively treat it," senior investigator Kenneth Hargreaves, chair of the Department of Endodontics in the Dental School at the UT Health Sciences Center, said in an UT news release. "These data demonstrate, for the first time, that OLAMs constitute a new family of ... Read more

Related support groups: Pain, Back Pain, Headache, Fibromyalgia, Migraine, Muscle Pain, Neuralgia, Breakthrough Pain, Migraine Prevention, Sciatica, Neck Pain, Herniated disc, Scoliosis, Cluster Headaches, Migraine Prophylaxis, Spondylolisthesis, Frozen Shoulder, New Daily Persistent Headache, Costochondritis, Epicondylitis - Tennis Elbow

Three-Fourths of Cancer Patients Have Severe Flares of Pain

Posted 29 Jan 2010 by Drugs.com

FRIDAY, Jan. 29 – Breakthrough cancer pain is a major challenge for 75 percent of adult cancer patients, according to new survey findings released by the American Pain Foundation. Breakthrough cancer pain refers to sudden, temporary flares of severe pain that occur even when a patient is taking pain medication. "We're not talking about minor aches and pain. These severe flares of pain often strike without warning, leaving many people fearful of the next crippling episode and unduly burdening patients and their families," Will Rowe, chief executive officer of the American Pain Foundation, said in a news release from the foundation. "Effective pain management is critical to restoring the quality of life these individuals so rightfully deserve," he added. The survey included 545 adults aged 18 and older who've been diagnosed with cancer, are currently living with cancer-related pain, are ... Read more

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