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Related terms: Brain Cancer, Brain Tumor, metastatic, Cancer, Brain, Intracranial Tumors

Childhood Cancer Tied to Raised Risk for Other Ills in Adult Life

Posted 15 days ago by

WEDNESDAY, Nov. 11, 2015 – Childhood cancer survivors are at increased risk for diabetes and other autoimmune diseases, a new study suggests. "Cure is no longer a sufficient goal in childhood cancer care," the researchers wrote. "As the vast majority of these patients survive, attention must be paid to their long-term quality of life and health challenges." In the study, the investigators analyzed data from more than 20,000 adults in Denmark, Iceland and Sweden, who had cancer before the age of 20 and survived for at least one year, and compared them to nearly 126,000 adults who did not have childhood cancer. Over an average follow-up of 15 to 19 years, 3.6 percent of childhood cancer survivors were treated in a hospital at least once for an autoimmune disease. That rate is 40 percent higher than among the adults who did not have childhood cancer, according to Dr. Anna Sallfors ... Read more

Related support groups: Diabetes, Type 2, Cancer, Leukemia, Autoimmune Disorders, Brain Tumor, Hodgkin's Lymphoma

Childhood Brain Tumor Survivors May Have Memory Troubles

Posted 2 Oct 2015 by

FRIDAY, Oct. 2, 2015 – Adult survivors of childhood brain tumors appear to have worse working memory than other adults, a small study finds. Researchers tested 17 adult survivors of pediatric brain tumors in the posterior fossa part of the brain. Then they tested a control group of 17 healthy adults. The brain tumor survivors scored significantly lower on tests of working memory, the study found. Working memory is the ability to retain and use information for short periods of time. The researchers said working memory is an important component of higher-level thinking. Brain scans showed that different areas of the brain appeared to "activate" more in brain tumor survivors during a verbal working memory task compared to healthy adults. Increased activation in those areas was linked to worse performance on more demanding working memory tasks, the researchers said. "Our goal was to ... Read more

Related support groups: Brain Tumor, Mild Cognitive Impairment

Signs of Brain Tumor May Show in Blood Years Before Diagnosis

Posted 18 Sep 2015 by

FRIDAY, Sept. 18, 2015 – Brain tumors known as gliomas usually produce symptoms several months before they're diagnosed, but new research found changes in immune function may occur up to five years before these cancers are detected. "Now, clinicians don't have any way to detect the tumors until patients have symptoms, which is typically three months before diagnosis. I see something five years before," study author Judith Schwartzbaum, an associate professor of epidemiology at Ohio State University, in Columbus. Researchers analyzed blood samples collected over 40 years in Norway from people getting annual checkups or donating blood. Norway also has a cancer registry, enabling the researchers to identify blood samples of people who developed a brain tumor. The blood samples were collected an average of 15 years before tumors were detected. Specifically, the researchers compared ... Read more

Related support groups: Allergies, Allergic Reactions, Brain Tumor, Diagnosis and Investigation, Malignant Glioma

Excess Weight Linked to Brain Cancer Risk in Study

Posted 16 Sep 2015 by

WEDNESDAY, Sept. 16, 2015 – Weight and physical activity levels may affect the risk of a certain brain cancers, new research suggests. Excess weight was associated with a higher risk of a type of brain cancer known as meningioma. Obesity increased the risk of meningioma by 54 percent, and being overweight upped the risk by 21 percent, the study found. On the other hand, people who were physically active reduced the risk of meningioma by 27 percent, the researchers said. "There are very few known preventive factors for these tumors," said study author Gundula Behrens, from the department of epidemiology and preventive medicine at the University of Regensburg in Germany. "According to our study, reducing excess weight and adopting a physically active lifestyle may help prevent meningiomas." The study also found that being heavier was not linked to the risk of a second, deadlier form of ... Read more

Related support groups: Obesity, Brain Tumor

Removing All Visible Cancer Is Key to Treating Aggressive Brain Tumors

Posted 14 Sep 2015 by

MONDAY, Sept. 14, 2015 – Surgery that removes all visible cancer significantly improves the chances of survival for children with aggressive brain tumors, especially girls. That's the finding of a study that included almost 100 children treated for high-grade glioma brain cancer between 1988 and 2010. These rare brain tumors occur in fewer than one in 100,000 children and teens. After two years, the overall survival rate was 45 percent; 25 percent had no cancer progression. Surgery to remove all visible signs of cancer was successful in one-third of the children. Their median survival was 3.4 years, compared with 1.6 years for those who did not have all visible cancer removed. Median means half of the children lived longer, half did not. The survival benefit after successful surgery was much greater in girls, with median survival of 8.1 years. Boys had a median survival of 2.4 years. ... Read more

Related support groups: Brain Tumor, Glioblastoma Multiforme, Neurosurgery, Malignant Glioma

Treatments for Brain Cancer Take Heavy Toll on the Brain

Posted 3 Sep 2015 by

THURSDAY, Sept. 3, 2015 – Radiation and chemotherapy can cause structural changes in the healthy brain tissue of patients with glioblastoma brain tumors, a new study finds. The research included 14 glioblastoma patients who underwent 35 weeks of combined radiation and chemotherapy (chemoradiation) after having their tumors surgically removed. The patients had brain scans before and after chemoradiation, but an adequate number of images were obtained from only eight of the patients. Those images revealed a significant decrease in whole brain volume – the overall amount of brain tissue – throughout chemoradiation. The reduced amount of brain tissue became apparent within a few weeks after the start of chemoradiation and was primarily seen in gray matter. The scans also showed that the size of the brain's ventricles – cerebrospinal fluid-filled spaces deep within the brain – grew ... Read more

Related support groups: Brain Tumor, Glioblastoma Multiforme, Malignant Glioma

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Femara, Lupron Depot, Tretinoin, Gleevec, Fluorouracil, Lung Cancer, Rituxan, Colorectal Cancer, Renal Cell Carcinoma

Patients with Low-Grade Brain Tumors Living Longer

Posted 1 Jul 2015 by

WEDNESDAY, JuLY 1, 2015 – Survival has improved for adults with low-grade brain tumors, known as gliomas, a new study finds. Low-grade gliomas grow slowly but are deadly. Because they're uncommon, they are not well-studied, said the researchers from the University of California, San Diego, School of Medicine. The best ways to manage these tumors are also controversial. There is little consensus on whether or when to use radiation or what type of surgery or chemotherapy patients should undergo. "An understanding of how our treatments affect the survival of low-grade glioma patients will better enable us to help these patients," senior study author Dr. Clark Chen, vice chairman of research and academic development in neurosurgery, said in a university news release. For the study, published July 1 in Neuro-Oncology: Clinical Practice, researchers examined data compiled in a U.S. cancer ... Read more

Related support groups: Cancer, Brain Tumor, Malignant Glioma

Technology May Help Surgeons Tell Brain Cancer From Healthy Tissue

Posted 18 Jun 2015 by

THURSDAY, June 18, 2015 – Researchers are making progress in developing an ultrasound-like technology that helps brain surgeons distinguish between brain tumors and normal tissue. In the new study, researchers report how the technology worked on human brain tissue. But, the technology hasn't yet been tested in living people. "Hopefully this summer we'll unroll the first preliminary studies, and we'll begin to use it in patients," said study co-author Dr. Alfredo Quinones-Hinojosa, professor of neurological surgery and oncology and director of the Brain Tumor Surgery Program at Johns Hopkins University School of Medicine in Baltimore. Currently, he said, "we agonize because many times we can't tell what is tumor and what is normal brain." The study appears in the June 17 issue of Science Translational Medicine. About 70,000 people are diagnosed with brain cancer in the United States ... Read more

Related support groups: Brain Tumor, Diagnosis and Investigation, Head Imaging

Genetic Characteristics of Brain Tumors Key to Treatment: Studies

Posted 11 Jun 2015 by

Treatment of brain tumors can be improved by first determining their genetic features, rather than the current standard practice of analyzing tissue samples under a microscope, according to two new studies. Experts say the findings published Wednesday in the New England Journal of Medicine are an important advance in what's called precision medicine, in which cancer treatments are individualized according to the genetic characteristics of patients' tumors, The New York Times reported. This approach could change the way that thousands of brain tumor patients are diagnosed and treated. "Prognosis is going to be more accurately delineated by these kinds of genetic subtypes, outstripping the value of looking through a microscope," Dr. David Langer, chief of neurosurgery at Lenox Hill Hospital in New York, told The Times He was not involved in the studies. The use of genetics to help guide ... Read more

Related support groups: Brain Tumor, Diagnosis and Investigation

Blood Thinners OK for Cancers That Spread to Brain, Study Finds

Posted 2 Jun 2015 by

TUESDAY, June 2, 2015 – Blood-thinning drugs are safe for treating blood clots in patients with cancer that has spread to the brain from other areas of the body, according to new research. Cancer normally increases a person's risk of blood clots, the study authors explained in a news release from the American Society of Hematology. When a cancer patient develops a clot, a blood thinner – also called an anticoagulant – is often added to the cancer treatment regimen to prevent the risk of blood clots traveling to the lungs. Such a clot can be fatal. However, if cancer spreads from other parts of the body to the brain (called brain metastases), doctors are hesitant to prescribe blood thinners because of concern they might cause bleeding in the head, which is already a risk for these patients, the study authors added. The new findings show that the use of blood thinners in these patients ... Read more

Related support groups: Cancer, Warfarin, Coumadin, Xarelto, Pradaxa, Lovenox, Heparin, Brain Tumor, Eliquis, Rivaroxaban, Enoxaparin, Clexane, Apixaban, Fragmin, Arixtra, Hep-Pak, Fondaparinux, Innohep, Dalteparin, Jantoven

Targeted Radiation to Treat Brain Tumors May Be Best: Study

Posted 1 Jun 2015 by

SUNDAY, May 31, 2015 – Using radiation on the entire brain to prevent new tumors from forming in patients whose cancer has spread to the brain can have a devastating effect on their ability to think and remember, compared with more targeted treatment, new findings show. Nearly all patients who received whole-brain radiation therapy – 92 percent – experienced a decline in memory and verbal ability, researchers reported Sunday at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago. By comparison, only 64 percent of patients who were given targeted radiosurgery, which focuses on a limited and tightly controlled area of the brain, experienced declines in mental ability. "Essentially, the brain does not like to be irradiated," said senior study author Dr. Jan Buckner, a professor of oncology at the Mayo Clinic in Rochester, Minn. The study also found that patients ... Read more

Related support groups: Brain Tumor, History - Radiation Therapy

Harnessing the Power of the Poliovirus as a Cancer Cure

Posted 31 Mar 2015 by

Polio, a highly infectious and crippling disease, was certainly one of the most feared viruses in the 20th century. Each year, thousands of children were left paralyzed. Polio has been successfully eliminated in the U.S. for decades due to a widespread vaccine program. So why would a group of researchers be interested in injecting the poliovirus directly into the brain of a patient? Clinical trials are now ongoing and research is revisiting the poliovirus in new and hopeful ways, ironically to help battle deadly cancers. Glioblastoma multiforme is one of the most common and fatal brain cancers. Gliobastomas are aggressive tumors that occur in the brain or spinal cord leading to headaches, nausea, seizures, blurred vision and a host of other unpleasant effects. The tumors grow quickly and often leave patients with only months to live. Treatments for glioblastoma involve surgery to ... Read more

Related support groups: Cancer, Brain Tumor, Glioblastoma Multiforme, Malignant Glioma

Privately Insured Brain Tumor Patients May Fare Better

Posted 9 Mar 2015 by

MONDAY, March 9, 2015 – Brain tumor patients with private health insurance do better than those who have Medicaid coverage or are uninsured, a new study finds. Researchers analyzed data from more than a half-million brain tumor-related hospitalizations in the United States between 2002 and 2011. Compared to uninsured or Medicaid patients, those with private insurance had fewer medical complications and were less likely to develop new health problems in the hospital. They also had shorter hospital stays and were 25 percent less likely to die while in the hospital, the researchers found. Patients with private health insurance were also less likely to end up in a nursing home, rehabilitation center or hospice after leaving the hospital, according to the study recently published online in the journal Neurosurgery. By the time brain tumor patients are hospitalized, much has already occurred ... Read more

Related support groups: Brain Tumor

New Techniques Outline Tumors' Location in the Brain

Posted 15 Feb 2015 by

FRIDAY, Feb. 13, 2015 – Brain tumors are notoriously tricky for surgeons, who may leave too much cancerous tissue behind or cut into vital, healthy brain tissue. However, two new studies describe devices that help surgeons and nonsurgical physicians better understand the outline and location of cancerous tissue in the brain, potentially improving outcomes for patients. One device, a handheld fiber optic probe, could help surgeons see cancer cells lying at the margins of brain tumors in real time, so they can be removed with more accuracy. The other device is a PET scan that allows doctors to gauge the size and area of a brain tumor. Seeing the outlines of tumors more accurately might help physicians better assess the benefits of chemotherapy or radiation treatment, the researchers explained. Both studies came as welcome news to experts. "We are always happy to see new research that is ... Read more

Related support groups: Surgery, Brain Tumor, Diagnosis and Investigation

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