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Chemo + Radiation Best for Bladder Cancer, Study Finds

Posted 18 Apr 2012 by Drugs.com

WEDNESDAY, April 18 – The addition of two well-tolerated chemotherapy drugs to radiation therapy led to significantly longer survival rates among patients with muscle-invasive bladder cancer. In a new study splitting 360 patients into groups receiving radiation alone or radiation plus chemotherapy, British researchers found that those undergoing combined therapies had a 67 percent rate of local disease-free survival after two years, compared with 54 percent in the radiation group. Five-year overall survival rates were 48 percent in the chemo-radiation group, compared with 35 percent in the radiation-only group. "Overall, the results establish that the addition of chemotherapy to radiotherapy should become standard practice for organ-preserving treatments of bladder cancer," said Dr. Manish Vira, director of the fellowship program in urologic oncology at the Arthur Smith Institute for ... Read more

Related support groups: Fluorouracil, Bladder Cancer, Mitomycin, Mutamycin, Adrucil

Science Probes How Probiotic Yogurts Affect Your Gut

Posted 26 Oct 2011 by Drugs.com

WEDNESDAY, Oct. 26 – Researchers have put the health promises of popular probiotic yogurts to the test and found they may alter the way in which food is metabolized. But whether that means probiotic foods and supplements can improve your health remains to be seen, they said. "Federal regulatory agencies are increasingly interested in evaluating all the health claims being made by probiotic food manufacturers," said study co-author Dr. Jeffrey Gordon, a biologist and director of the Center for Genome Sciences at Washington University School of Medicine, in St. Louis. "So what we did was try to develop a model for the human gut that can give us a way to measure the effects." What they saw, Gordon said, "is that adding a few billion of these microbial organisms to a gut community already containing tens of trillions of bacteria can, in fact, influence the metabolism of food ingredients. ... Read more

Drinking More Fluids Could Lower Men's Bladder Cancer Risk

Posted 25 Oct 2011 by Drugs.com

TUESDAY, Oct. 25 – Men who drink plenty of low-sugar fluids may reduce their risk for bladder cancer, new research suggests. Although the reason for the association between fluid intake and protection against cancer remains unknown, researchers theorize the fluids may flush out potential cancer-causing agents before they have a chance to cause any damage. In conducting the study, Jiachen Zhou, a doctoral candidate in epidemiology at Brown University, and colleagues evaluated the fluid intake of nearly 48,000 men who were part of a long-term study. The men, who were aged 40 to 75 when they enrolled in the study in 1986, answered a questionnaire about their fluid intake every four years for more than two decades. The investigators found that the men with a high daily fluid intake, or those who drank more than 10 cups (2,531 milliliters) per day, had a 24 percent reduced risk for bladder ... Read more

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Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Bladder Cancer Patients Not Getting Recommended Care: Study

Posted 12 Jul 2011 by Drugs.com

TUESDAY, July 12 – Most patients with a certain type of bladder cancer don't get the recommended treatments, which greatly increases their risk of experiencing a recurrence of their disease, researchers say. New research published online July 11 in Cancer showed that just one of 4,545 people with high-grade, noninvasive bladder cancer was treated according to the comprehensive care guidelines set by the American Urological Association and the National Comprehensive Cancer Network. All of the patients had primary bladder cancer that had not yet invaded their bladder muscle. These people have up to a 70 percent chance of their cancer returning after treatment, and as much as a 50 percent chance of the cancer becoming more aggressive and spreading to surrounding organs after initial treatment. Following the treatment guidelines in full may protect patients from potentially fatal cancer ... Read more

Related support groups: Bladder Cancer

Fewer Cancer Patients May Be Depressed Than Thought

Posted 20 Jan 2011 by Drugs.com

THURSDAY, Jan. 20 – The rate of depression among cancer patients may be lower than previously believed, a new study indicates. An international team of researchers analyzed 94 studies involving more than 14,000 patients and found that about one-sixth of cancer patients suffer depression and about one-third have a more widely defined mood disorder. Only modest rates of depression and anxiety occurred in cancer patients in the first five years after diagnosis, which suggests that depression is not inevitable in these patients, the researchers said. Only when it was combined with other mood disorders was depression common, occurring in 30 percent of hospitalized cancer patients. The study is published online Jan. 19 in The Lancet Oncology. Rates of depression and anxiety were not significantly different between patients receiving palliative care (care designed to ease pain and increase ... Read more

1 in 5 Cancer Survivors Suffers Chronic Pain, Study Finds

Posted 20 Jan 2011 by Drugs.com

WEDNESDAY, Jan. 19 – More than 40 percent of cancer survivors experience pain, and the risk is highest among black and female patients, finds a new study. Researchers at the University of Michigan Health System surveyed nearly 200 U.S. cancer survivors and found that 43 percent had experienced pain since their diagnosis, and 20 percent suffered chronic cancer-related pain at least two years later. Among white patients, the most significant source of pain was cancer surgery (53.8 percent), and among black patients the greatest source of pain was cancer treatment (46.2 percent), according to the report. In addition, the study found that compared to men, women had more pain, more pain flare-ups, more disability due to pain and were more depressed because of pain. The authors also noted that black patients were more likely to report greater severity of pain and more pain-related ... Read more

Demand for Radiation Therapy Predicted to Exceed Supply

Posted 21 Oct 2010 by Drugs.com

THURSDAY, Oct. 21 – Over the next decade, the growth in demand for radiation therapy in the United States will be 10 times greater than the increase in new radiation oncologists, a difference that could affect cancer patients' access to treatment, according to a new study. Between 2010 and 2020, the number of patients requiring radiation therapy will increase 22 percent but the number of full-time radiation oncologists entering the workforce will increase just 2 percent, said researchers at the University of Texas M.D. Anderson Cancer Center in Houston and colleagues. They based their predictions on projections that this year 3,943 radiation oncologists will treat an estimated 470,000 patients in the United States. The large increase in demand for radiation therapy will be partly due to growing numbers of older adults and minorities, groups in which certain types of cancers are more ... Read more

Cancer Patients' Secondary Symptoms Need Attention: Study

Posted 11 Oct 2010 by Drugs.com

MONDAY, Oct. 11 – Many cancer patients with pain or depression also experience physical symptoms, such as fatigue, dry mouth and nausea, that can cause disability, a new study shows. Doctors need to recognize and treat these symptoms in order to improve quality of life for cancer patients, said Dr. Kurt Kroenke, of the Richard Roudebush VA Medical Center, Indiana University, and Regenstrief Institute Inc. in Indianapolis, and colleagues. They analyzed data from 405 cancer patients who had either pain or depression and found that all the patients had at least one of 22 physical symptoms examined in the study. More than half of patients reported 15 of the 22 symptoms. The most common symptoms were fatigue (97.5 percent), difficulty sleeping (about 79 percent), pain in limbs or joints (78 percent), back pain (nearly 75 percent) and memory problems (72 percent). The patients also reported ... Read more

Meat Compounds May Boost Bladder Cancer Risk

Posted 2 Aug 2010 by Drugs.com

WEDNESDAY, July 28 – Certain compounds used in meat processing may increase the risk of bladder cancer, a new study from the National Institutes of Health and the AARP shows. U.S. researchers analyzed data from about 300,000 men and women, aged 50 to 71, from eight states who took part in a large prospective study on diet and health. At the start of the study in 1995/96, the participants provided information about their lifestyle and dietary habits. During eight years of follow-up, 854 participants were diagnosed with bladder cancer. People whose diets had the highest levels of dietary nitrite (from all sources and not just from meat) and those whose diets had the highest amounts of nitrate plus nitrite from processed meats were 28 percent to 29 percent more likely to develop bladder cancer than those who consumed the lowest amounts of those compounds, according to the NIH-AARP Diet ... Read more

Related support groups: Bladder Cancer

Study Suggests Painters Face Increased Risk of Bladder Cancer

Posted 20 Jul 2010 by Drugs.com

TUESDAY, July 20 – Professional painters may face an increased risk for bladder cancer and that risk seems to rise with the number of years they work, a new study suggests. Researchers analyzed nearly 3,000 cases of bladder cancer in professional painters that were reported in 41 previous studies. Some of those studies also classified plasterers, glaziers, wallpaper hangers, artists and decorators as painters. After taking into account smoking (a key risk factor for bladder cancer), the review authors concluded that painters were 30 percent more likely to develop bladder cancer than the general population. While there was some evidence that female painters were more likely to develop bladder cancer than male painters, only four of the studies included separate results for women. The number of years a person worked as a painter had a significant effect on bladder cancer risk. People who ... Read more

Related support groups: Bladder Cancer

Many Docs Deliver Cancer Diagnosis Badly: Study

Posted 7 Jul 2010 by Drugs.com

WEDNESDAY, July 7 – One patient found out he had cancer by reading his radiology report. Another got the news when her neurologist called to say he had arranged for her to see a neurosurgeon. When she asked why, the doctor told her she had a brain tumor and hung up. A third learned she had breast cancer listening to her answering machine with her grandson sitting on her lap. A new study about how people learn of cancer diagnoses finds that many doctors have poor communication skills and often leave patients stranded with devastating information about a deadly illness, sometimes in a public setting. One-third of the cancer patients in the U.S. National Cancer Institute study recalled being told on the phone, in an emergency room, radiology department or other public hospital setting that they had cancer, most often leukemia, lymphoma or brain tumors. "It's really dismaying to think that ... Read more

Cost-Conscious Cancer Survivors Skip Care

Posted 14 Jun 2010 by Drugs.com

MONDAY, June 14 – Millions of Americans with a history of cancer, particularly people under age 65, are delaying or skimping on medical care because of worries about the cost of treatment, a new study suggests. The finding raises troubling questions about the long-term survival and quality of life of the 12 million adults in the United States whose lives have been forever changed by a diagnosis of cancer. "I think it's concerning because we recognize that cancer survivors have many medical needs that persist for years after their diagnosis and treatment," said study lead author Kathryn E. Weaver, an assistant professor in the Department of Social Sciences & Health Policy at Wake Forest University Baptist Medical Center in Winston-Salem, N.C. The report was published online June 14 in Cancer, a journal of the American Cancer Society. Cost concerns have posed a threat to cancer ... Read more

Meat Lovers Face Greater Risk of Bladder Cancer

Posted 20 Apr 2010 by Drugs.com

TUESDAY, April 20 – Eating meat frequently, especially when it's well-done or cooked at high temperatures, can boost the risk of bladder cancer, a new study suggests. "It's well-known that meat cooked at high temperatures generates heterocyclic amines that can cause cancer," study presenter Jie Lin, an assistant professor in the University of Texas M. D. Anderson Cancer Center's department of epidemiology, said in a news release from the cancer center. "We wanted to find out if meat consumption increases the risk of developing bladder cancer and how genetic differences may play a part." This study tracked 884 patients with bladder cancer and 878 who didn't have it. They responded to questionnaires about their diets. Those who ate the most red meat were almost 1.5 times more likely to develop bladder cancer than those who ate the least. The study linked steak, pork chops and bacon to ... Read more

Related support groups: Bladder Cancer

Pain Relief Often Delayed for Cancer Patients

Posted 16 Mar 2010 by Drugs.com

TUESDAY, March 16 – Palliative care services, which help people who are seriously ill relieve symptoms such as pain, are now found at most U.S. cancer centers, but many programs don't interact with patients until it's too late, study findings show. Dr. David Hui, of the University of Texas M.D. Anderson Cancer Center in Houston, and his colleagues surveyed 71 U.S. National Cancer Institute-designated cancer centers and randomly surveyed 71 other cancer centers. They received responses from 71 percent of 142 executives and 82 percent of 120 program leaders. The researchers also found that the NCI cancer centers were more likely to have palliative care programs and physicians. A report on the survey was published in the March 17 issue of the Journal of the American Medical Association. "Palliative care outpatient clinics, inpatient consultation teams, palliative care units and hospices ... Read more

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