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TB Vaccine May Work Against Multiple Sclerosis: Study

Posted 1 day 13 hours ago by Drugs.com

WEDNESDAY, Dec. 4, 2013 – A vaccine normally used to thwart the respiratory illness tuberculosis also might help prevent the development of multiple sclerosis, a disease of the central nervous system, a new study suggests. In people who had a first episode of symptoms that indicated they might develop multiple sclerosis (MS), an injection of the tuberculosis vaccine lowered the odds of developing MS, Italian researchers report. "It is possible that a safe, handy and cheap approach will be available immediately following the first [episode of symptoms suggesting MS]," said study lead author Dr. Giovanni Ristori, of the Center for Experimental Neurological Therapies at Sant'Andrea Hospital in Rome. But, the study authors cautioned that much more research is needed before the tuberculosis vaccine could possibly be used against multiple sclerosis. In people with MS, the immune system ... Read more

Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia

Posted 14 Feb 2013 by Drugs.com

THURSDAY, Feb. 14 – Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life. Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found. On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago. One expert not connected to the study stressed that cancer patients need to put the findings into perspective. "It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," ... Read more

Banning Vaccine Preservative Would Hurt Kids in Poor Nations: Experts

Posted 17 Dec 2012 by Drugs.com

MONDAY, Dec. 17 – A United Nations proposal to ban the vaccine preservative thimerosal – which contains a form of mercury – should not go through, says a leading group of U.S. pediatricians. The American Academy of Pediatrics (AAP) joins the World Health Organization (WHO) in urging the U.N. to drop the proposal from an international treaty seeking to cut down on mercury exposures in a variety of ways. Both the WHO and AAP say a thimerosal ban could keep children in poor nations from getting needed vaccines. The AAP, which announced its stance to members in June, reiterates its position and provides three commentaries on the issue in the January print edition of Pediatrics, published online Dec. 17. Thimerosal contains a form of mercury called ethyl mercury. For years it was used in certain vaccines, but U.S. health officials decided in 1999 that thimerosal should be removed from ... Read more

TB Vaccine Promising as New Way to Fight Type 1 Diabetes

Posted 8 Aug 2012 by Drugs.com

WEDNESDAY, Aug. 8 – A small trial of a vaccine already approved for tuberculosis found that the vaccine can kill the rogue autoimmune cells that are active players in type 1 diabetes. There were no changes, however, in the need for insulin among those with longstanding diabetes who got the vaccine, the researchers added. "What we saw with two vaccines, given four weeks apart, was the death of bad T-cells," said study author Dr. Denise Faustman, director of the immunobiology laboratory at Massachusetts General Hospital in Boston. "We also saw that regulatory T-cells came on – these are the good-guy T-cells. And the pancreas went on briefly, and this was in people who were 15 years out from their type 1 diagnosis." "This doesn't mean that people were throwing their insulin syringes away," Faustman said. "But the exciting part is that even decades after the disease begins, the cells in ... Read more

Related support groups: Diabetes, Type 1, BCG, Tice BCG, TheraCys, Tice BCG Vaccine

Too Few American Adults Getting Needed Vaccinations: CDC

Posted 2 Feb 2012 by Drugs.com

THURSDAY, Feb. 2 – Each year, some 45,000 Americans die from diseases that could have been prevented by vaccines, health officials said Thursday. Despite this, the number of American adults who get needed vaccines remains low, according to the U.S. Centers for Disease Control and Prevention. "There were some modest increases in coverage, but for very few vaccines," said Dr. Carolyn B. Bridges, associate director of adult immunization at the CDC and co-author of the report. "Coverage is much lower than we would like to see it." The data was published in the Feb. 3 issue of the CDC's Morbidity and Mortality Weekly Report. According to the report, 2010 (the latest year covered by the report) saw only a small increase in the rate of uptake for just three vaccines. The rate of the tetanus, diphtheria, and acellular pertussis (Tdap) vaccination increased 1.6 percent, to 8.2 percent. Tdap ... Read more

Infant Vaccines May Work Better If Given in Afternoon

Posted 30 Nov 2011 by Drugs.com

WEDNESDAY, Nov. 30 – As many parents can attest, a rough night may follow when their baby has been to the doctor for their first shots, due to increased fussiness or fever from the immunizations. But a new study suggests that the time of day that the shots are given may make a difference in both sleep and immune response. Research has shown that immunizations "take hold" more strongly when an infant has a long, deep sleep afterward, which is why some parents give acetaminophen (Tylenol) proactively. According to the new study, published online Nov. 28 and in the December print issue of Pediatrics, infants may sleep more soundly when their shots are given after 1:30 p.m., regardless of whether they have been given any medication. In the study of 70 infants who were getting their first series of vaccines at around 2 months of age, mothers either were told to give their infants a ... Read more

Some U.S. Parents Ignoring Vaccination Guidelines

Posted 3 Oct 2011 by Drugs.com

MONDAY, Oct. 3 – More than one in 10 parents don't follow recommended vaccination guidelines for their children, opting instead for an "alternative" schedule that could involve skipping doses or delaying shots. And parents who do follow official recommendations show some inclination to move toward an alternative schedule, according to new research. The findings alarm the authors of the study, published in the November issue of Pediatrics. "This really highlights to me that there's probably going to be a continuing increase in the number of parents who choose to follow alternative schedules," said study author Dr. Amanda Dempsey. "We really need to start allocating government and educational resources to stem the growing tide of discontent about vaccines among parents." This isn't the first time investigators have noticed the shift. "There's been a trend over the past couple of decades ... Read more

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Vaccinations Aren't Just for Kids

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Public health experts often focus immunization awareness efforts toward protecting children, and with good reason: Facing a potentially bewildering schedule of vaccinations for their young ones, parents usually need all the help they can get. But vaccinations aren't just kid stuff. Medical science is creating an increasing number of immunizations targeted at adults, to help them avoid life-threatening diseases in middle-age and opportunistic infections when they're older. "Immunization is a life-long issue that we need to pay a lot of attention to," said Dr. Georges C. Benjamin, executive director of the American Public Health Association. Some adult vaccinations are very well-known, like the annual shot that aims to prevent the spread of influenza. "You need an influenza shot every year," Benjamin said. "Part of that is because the virus changes every year, ... Read more

Parents Still Worried About Vaccine Safety

Posted 1 Mar 2010 by Drugs.com

MONDAY, March 1 – Although most American parents vaccinate their children, many are concerned about the safety of vaccines and some choose not to have their children protected from potentially deadly diseases, a new study found. Researchers at the University of Michigan found that while 90 percent of parents say vaccines are a good way to protect their kids, and 88 percent follow their doctor's vaccination recommendations, 54 percent are worried about serious side effects. "Parents' hesitation about vaccines has, in some cases, led them to postpone vaccinations for their children," said lead researcher Dr. Gary L. Freed, director of the Child Health Evaluation and Research Unit at the University of Michigan Health System. "The study found that 12 percent of parents have refused at least one vaccine that their children's doctor recommended." "When parents refuse vaccines, they place ... Read more

Too Few Adults Get Recommended Vaccinations

Posted 4 Feb 2010 by Drugs.com

THURSDAY, Feb. 4 – Most parents make sure their children get all their vaccinations, but when it comes to adults these protective shots often fall by the wayside, a new report shows. In fact, 40,000 to 50,000 American adults die each year from diseases that vaccines could have prevented, according to the report, Adult Immunization: Shots to Save Lives. The report was released jointly Thursday by the Trust for America's Health, the Infectious Diseases Society of America and the Robert Wood Johnson Foundation. "This country does not have an effective strategy for immunizing adults against infectious diseases," Jeffrey Levi, executive director of Trust for America's Health, said during a morning teleconference. "Thousands of lives could be saved each year if we could increase the number of adults who receive routine and recommended vaccinations. We need a national strategy to make ... Read more