Amyotrophic Lateral Sclerosis Blog

Includes: ALS (amyotrophic lateral sclerosis), Amyotrophic Lateral Sclerosis (ALS), Lou Gehrig's Disease, Motor Neurone Disease, ALS

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Finding Raises Hope for Treating ALS

Posted 3+ months ago by Drugs.com

MONDAY, JUNE 15 – Researchers now believe that ALS, or amyotrophic lateral sclerosis, starts well before its debilitating symptoms appear, a finding that they say could eventually lead to an effective treatment.

Protein clumps in cells that show up only after damage has occurred, rather than at the onset of the disease, appear responsible for the paralyzing course of ALS (amyotrophic lateral sclerosis), according to University of Florida researchers.

The research team found that the formation of these clumps of defective proteins and cell matter, called "protein aggregates," actually signals that ALS is progressing at a rapid pace. Read more...

Related support groups: Amyotrophic Lateral Sclerosis

Gene Mutation Linked to Inherited ALS

Posted 3+ months ago by Drugs.com

THURSDAY, Feb. 26 – A new gene has been identified as playing a role in the inherited form of amyotrophic lateral sclerosis, or ALS, say researchers at the University of Massachusetts Medical School and King's College, London.

The discovery, a mutation in the FUS/TLS gene, is the fourth gene linked to the neurological disorder, also known as Lou Gehrig's disease. The finding was reported in the Feb. 27 issue of the journal Science. Read more...

Related support groups: Amyotrophic Lateral Sclerosis

Growth Hormone Won't Fight ALS

Posted 3+ months ago by Drugs.com

MONDAY, Nov. 24 – The growth hormone known as insulin-like growth factor-1 (IGF-1) showed no benefit for people with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

The two-year U.S. study included 330 patients from 20 medical centers.

Two previous, shorter studies had produced conflicting results. One North American study found that IGF-1 was beneficial, while a European study found no benefit for people with ALS, a progressive, fatal neurodegenerative disease that causes muscles to weaken and deteriorate.

This new study concluded that IGF-1 does not slow progression of muscle weakness. Read more...

Related support groups: Amyotrophic Lateral Sclerosis

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