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Related terms: Presenile Dementia, SDAT, Senile dementia Alzheimer's Type, Alzheimers

Weight, Growth Early in Life May Affect Adult Brain

Posted 14 hours ago by

FRIDAY, Oct. 9, 2015 – Birth weight and growth during childhood could affect hearing, vision, thinking and memory later in life, a new study suggests. "Sensory problems and illness such as dementia are an increasing problem, but these findings suggest that issues begin to develop right from early life," said the study's leader, Dr. Piers Dawes. He is a lecturer in audiology at the University of Manchester's School of Psychological Sciences in England. "While interventions in adulthood may only have a small effect, concentrating on making small improvements to birth size and child development could have a much greater impact on numbers of people with hearing, vision and cognitive [mental] impairment," Dawes said in a university news release. However, the study findings don't mean that parents of children who don't physically match their average-sized peers at birth or as they're growing ... Read more

Related support groups: Obesity, Eye Conditions, Weight Loss, Dementia, Alzheimer's Disease, Macular Degeneration, Mild Cognitive Impairment, Hearing Loss, Prematurity/Underweight in Infancy

Depression Adds to Burden of Alzheimer's Caregivers, Study Finds

Posted 8 days ago by

THURSDAY, Oct. 1, 2015 – Depression increases the mental strain on people caring for loved ones recently diagnosed with Alzheimer's disease, a new study finds. The study included spouses and other family caregivers of 236 people in Finland who were diagnosed with very mild or mild Alzheimer's disease. The caregivers were followed for three years after their loved ones were diagnosed. The highest levels of mental stress occurred in caregivers who had depression when their loved one was diagnosed with Alzheimer's, the investigators found. "The occurrence of even mild depressive symptoms predicted a psychological load on the family caregiver irrespective of, for example, the progression of the disease," study author Tarja Valimaki said in a University of Eastern Finland news release. Valimaki is a clinical researcher in the university's department of nursing science. The researchers also ... Read more

Related support groups: Depression, Major Depressive Disorder, Alzheimer's Disease, Dysthymia, Seasonal Affective Disorder

Finding Disease Cures Can Take Up to a Century: Analysis

Posted 16 days ago by

THURSDAY, Sept. 24, 2015 – A team of scientists has looked back over decades of discovery to conclude that it can take dozens of years, even a century, for cumulative research to lead to a cure for a single disease. The finding is disheartening given the current U.S. government underfunding of the basic science needed to investigate diseases, said a team led by Dr. R. Sanders Williams, president of the San Francisco-based Gladstone Institutes, a biomedical research organization. "As shown by our analysis, new treatments depend upon a broad base of scientific knowledge plus special contributions from a few exceptional scientists," Williams said in an institute news release. For anyone suffering from an illness, the dream word is "cure." True cures for disease remain rare, though. But, in the new study the Gladstone team traced the long investigative paths linking generations of ... Read more

Related support groups: Diabetes, Type 2, Cancer, Parkinson's Disease, Heart Failure, Congestive Heart Failure, Diabetes, Type 1, Alzheimer's Disease, Diabetes Mellitus, Diagnosis and Investigation, Parkinsonism, Yervoy, Ipilimumab, Ivacaftor/lumacaftor, Ivacaftor, Orkambi, Kalydeco

Drug May Calm Agitation in Alzheimer's Patients

Posted 18 days ago by

TUESDAY, Sept. 22, 2015 – A drug that combines a cough suppressant with a heart medication might offer a safer option for calming the agitation that commonly affects people with Alzheimer's disease, an early clinical trial suggests. The study, of 220 Alzheimer's patients, found that the drug – called Nuedexta – generally eased agitation symptoms over 10 weeks. And it did not worsen patients' problems with memory, thinking and judgment, researchers reported in the Sept. 22/29 issue of the Journal of the American Medical Association. As Alzheimer's disease progresses, people often go through periods of agitation that can range from restlessness and pacing to aggressive behavior like yelling, fighting and destroying objects. If those issues can be managed without medication, that's always best, said Dr. Sam Gandy, a professor of neurology and psychiatry at Mount Sinai Hospital, in New ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Schizophrenia, Zyprexa, Risperdal, Risperidone, Schizoaffective Disorder, Latuda, Geodon, Saphris, Seroquel XR, Quetiapine, Alzheimer's Disease, Agitation, Olanzapine, Agitated State, Invega, Clozapine, Aripiprazole

Women the Bigger Losers in Terms of Alzheimer's Costs

Posted 15 Sep 2015 by

TUESDAY, Sept. 15, 2015 – The cost of caring for a woman with Alzheimer's disease is ultimately about six times more than it is for a man with this form of dementia, new research indicates. When the patient is a man, the true value of the time and energy a female family member typically puts into her caregiving job is 20 times greater than that performed by a male family member when the patient-caregiver roles are reversed, the Emory University researchers said. In other words, women perform more unreimbursed labor. And when men care for sick women, more money is spent on paid caregiving staff, driving up the overall cost, said study authors Zhou Yang and Allan Levey. The findings will appear in the September/October issue of the journal Women's Health Issues. "This study demonstrates the importance of policies to address the needs not only of patients but of caregivers, the majority ... Read more

Related support groups: Alzheimer's Disease

Tight Control of Type 2 Diabetes May Help Prevent Dementia

Posted 15 Sep 2015 by

TUESDAY, Sept. 15, 2015 – Keeping blood sugar levels in check may have a protective effect against dementia in people who have type 2 diabetes, new Swedish research suggests. "The positive association between [average blood sugar levels] and risk of dementia in fairly young patients with type 2 diabetes indicates a potential for prevention of dementia with improved blood sugar control," study author Dr. Aidin Rawshani, from the National Diabetes Register and Institute of Medicine in Gothenburg, Sweden, and colleagues wrote. However, the study wasn't able to definitively prove a cause-and-effect relationship between blood sugar levels and dementia; it was only able to show an association between these factors. The study included almost 350,000 people with type 2 diabetes. They were all registered in the Swedish National Diabetes Registry between January 2004 and December 2012. They had ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Lantus, Dementia, Glucophage, Novolog, Alzheimer's Disease, Glipizide, Humalog, Janumet, Glyburide, Actos, Lantus Solostar, Levemir, Invokana, Glimepiride, Novolin R, Amaryl, Mild Cognitive Impairment

Too Little Vitamin D May Hasten Mental Decline

Posted 15 Sep 2015 by

TUESDAY, Sept. 15, 2015 – Mental function may decline faster in older adults with low levels of vitamin D, a new study suggests. Among more than 380 people the researchers followed for an average of five years, those with dementia had the lowest levels of vitamin D. "It is unclear what vitamin D might be doing," said study author Joshua Miller, chair of the department of nutritional sciences at Rutgers University School of Environmental and Biological Sciences in New Brunswick, N.J. "There is good evidence that vitamin D gets into all cells of the body, including the brain," Miller said, so it's possible that vitamin D protects the brain from developing the plaques and tangles that are associated with Alzheimer's disease. Unfortunately, "there's a good chance that most people over 75 in the United States are vitamin D-deficient," he noted. Miller cautioned that there's no proof that ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Caltrate 600 with D, Calcium/Vitamin D, Os-Cal 500 with D, Citracal + D, Oysco 500 with D, Oyster Shell Calcium, Citracal Creamy Bites, Calcet, Calcarb with D, Calcium 600 D, Oyst-Cal-D, Citracal Regular, Os-Cal 500 + D, Oystercal-D, Os-Cal with D, Calvite P, Dical Captabs

Could Red Wine Ingredient Affect Progression of Alzheimer's?

Posted 11 Sep 2015 by

FRIDAY, Sept. 11, 2015 – High doses of resveratrol, a compound found in red wine and berries, may have some activity against Alzheimer's disease, a preliminary clinical trial suggests. Resveratrol is an antioxidant that certain plants produce to shield against stress from the environment. People ingest small amounts when they eat red grapes, red wine, berries or dark chocolate. Lab research has suggested that resveratrol might have some powers against the diseases of aging – including Alzheimer's disease. But evidence from human studies has been lacking. The new study, published Sept. 11 in Neurology, offers the first evidence that high-dose, "pharmaceutical-grade" resveratrol can get into the brains of people with mild to moderate Alzheimer's. What's more, it seems to stabilize levels of a protein that is linked to Alzheimer's progression. The study did not, however, show whether ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Resveratrol

Beware Unregulated Stem Cell Treatments, Experts Warn

Posted 9 Sep 2015 by

WEDNESDAY, Sept. 9, 2015 – Hundreds of clinics across the United States are offering unapproved stem cell treatments for conditions from baldness to heart failure and Alzheimer's disease, researchers report. "These for-profit stem cell clinics operate outside mainstream regulatory frameworks normally in place to protect patients," said study lead author Hermes Taylor-Weiner, of the University of California, San Diego, bioengineering department. "These clinics are selling stem cell treatments that have not been shown to be safe or effective, so they are unproven," he said. Stem cells have been touted as miracle cures for a variety of diseases, but the field is not as advanced as the public believes, according to the report in the Sept. 10 issue of the New England Journal of Medicine. "Patients need to have a healthy dose of skepticism when considering these treatments," Taylor-Weiner ... Read more

Related support groups: Diabetes, Type 2, Heart Failure, Congestive Heart Failure, Alzheimer's Disease

Type 2 Diabetes Linked to More Alzheimer's Brain 'Tangles'

Posted 2 Sep 2015 by

WEDNESDAY, Sept. 2, 2015 – People with type 2 diabetes may be more prone to developing the brain "tangles" associated with Alzheimer's disease, a new study suggests. The study found that people with type 2 diabetes had a greater accumulation of brain tangles – even if they were free of dementia or milder problems with memory and thinking. The findings, reported Sept. 2 in the journal Neurology, hint at one explanation for why people with type 2 diabetes have an increased risk of Alzheimer's disease. That is, type 2 diabetes may cause brain abnormalities that pile on to other degenerative changes that ultimately lead to dementia, explained study senior researcher Dr. Velandai Srikanth, a geriatrician at Monash University in Melbourne, Australia. However, he said, this study shows only a correlation between type 2 diabetes and brain tangles. It's not clear whether the type 2 diabetes is ... Read more

Related support groups: Diabetes, Type 2, Ischemic Stroke, Alzheimer's Disease

Too Much Weight in Middle Age Tied to Earlier Alzheimer's

Posted 1 Sep 2015 by

TUESDAY, Sept. 1, 2015 – Avoiding middle-age spread could be one way to delay the onset of dementia, a new study hints. Researchers found that among 142 elderly adults with Alzheimer's disease, those who were overweight at age 50 tended to develop the memory-robbing disorder earlier. On average, the study participants were 83 years old when diagnosed with Alzheimer's. But that age of onset varied according to people's weight at age 50: For each unit increase in body mass index (BMI), Alzheimer's set in about seven months earlier, on average. Other studies have found that obesity may boost the risk of developing Alzheimer's. But this research suggests it also speeds the onset, said senior researcher Dr. Madhav Thambisetty, of the U.S. National Institute on Aging. "We think that's important because one of the goals in Alzheimer's research is to find ways to delay the onset of the ... Read more

Related support groups: Obesity, Weight Loss, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Awareness of Memory Problems Fades a Few Years Before Dementia: Study

Posted 26 Aug 2015 by

WEDNESDAY, Aug. 26, 2015 – Older adults destined to develop dementia may start to lose awareness of their memory problems two to three years before the disease is full blown, a new study finds. That had been suspected, but not clearly shown before, said lead investigator Robert Wilson, senior neuropsychologist at the Rush Alzheimer's Disease Center in Chicago. "As researchers, we're very interested in what the experience of dementia is like for the individual," Wilson said. "It's important to understand its natural progression." The findings also offer some useful information for the average person, according to Wilson. "If you're aware enough to be worried about your memory, you probably don't have dementia," he said. Nor is it clear that you ever will, since memory issues do not mean a person is doomed to develop Alzheimer's or other forms of dementia. The findings, published in the ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia

Exercise, Supplements Like Fish Oil Won't Keep Elderly Sharper: Studies

Posted 25 Aug 2015 by

TUESDAY, Aug. 25, 2015 – Neither exercise nor supplements such as fish oil don't seem to do much to help keep older folks mentally sharp, two new studies found. The reports, published Aug. 25 in the Journal of the American Medical Association, cast doubts on two strategies purported to keep older brains younger and healthier. In one study, two years' worth of moderate exercise didn't seem to improve the brain power of people between 70 and 89 or lower their odds for dementia. Similarly, giving older adults fish oil or other supposed brain nutrients did not keep them sharper. The exercise study, which involved 1,600 sedentary adults, "is the largest and longest randomized trial of a physical activity intervention in older adults who were not already active and were at risk of losing their ability to walk," said Dr. Kaycee Sink, medical director of the Kulynych Memory Assessment Clinic ... Read more

Related support groups: Dementia, Dietary Supplementation, Alzheimer's Disease, Fish Oil, Lovaza, Mild Cognitive Impairment, Omega-3, Arteriosclerotic Dementia, Omacor, Omega-3 Polyunsaturated Fatty Acids, MaxEPA, Animi-3, Marine Lipid Concentrate, Doxycycline/Omega-3 Polyunsaturated Fatty Acids, Mi-Omega, MegaKrill, Omega-500, Lactobacillus Casei/omega-3 Polyunsaturated Fatty Acids, Omega Essentials, EPA Fish Oil

9 Factors You Can Control May Be Key to Alzheimer's Risk

Posted 21 Aug 2015 by

THURSDAY, Aug. 20, 2015 – Up to two-thirds of Alzheimer's cases worldwide may stem from any of nine conditions that often result from lifestyle choices, a broad research review suggests. Those include obesity (specifically, high body mass index, an indication of obesity, in midlife); carotid artery disease, in which plaque buildup narrows major neck arteries and slows blood supply to the brain; high blood pressure; depression; being frail; being poorly educated; having high levels of a naturally occurring amino acid known as homocysteine; and (specifically among those of Asian descent) being a smoker and/or having either type 2 diabetes. The implication: Taking steps to minimize or eliminate such conditions might reduce the long-term risk for developing Alzheimer's, a brain disorder that affects memory and thinking. It is the most common form of dementia among seniors. "The current ... Read more

Related support groups: Depression, High Blood Pressure, Diabetes, Type 2, Obesity, Hypertension, Smoking, Major Depressive Disorder, Alzheimer's Disease, Dysthymia, Coronary Artery Disease (CAD), Hypertensive Heart Disease

Why the Aging Brain Is More Vulnerable to Alzheimer's

Posted 20 Aug 2015 by

THURSDAY, Aug. 20, 2015 – Age is the greatest risk factor for Alzheimer's disease, and researchers now think they know why that's the case. New cutting-edge technology reveals that as you age, your brain becomes less and less capable of flushing away a toxic waste product of brain activity called beta-amyloid, the researchers said. Beta-amyloid proteins can clump together, forming larger amyloid plaques in the spaces between neurons. These amyloid plaques are a hallmark of Alzheimer's disease, the most common form of dementia. "This is a clue as to why age is the number one, two and three risk factor for Alzheimer's disease," said study senior author Dr. Randall Bateman, director of the Dominantly Inherited Alzheimer Network Trials Unit at the Washington University School of Medicine in St. Louis. "As we slow down our ability to clear away these sticky proteins, the risk of having ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

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