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Related terms: Presenile Dementia, SDAT, Senile dementia Alzheimer's Type, Alzheimers

Heart Disease, Alzheimer's Linked by Common Risk Factors

Posted 8 hours ago by Drugs.com

TUESDAY, July 28, 2015 – Some risk factors for heart disease may also be linked with Alzheimer's and other types of dementia, a new study reports. "We already know that vascular risk factors damage the brain and can result in cognitive [mental] impairment," study lead author Dr. Kevin King said in a news release from the journal Radiology. "Our findings give us a more concrete idea about the relationship between specific vascular risk factors and brain health," said King, an assistant professor of radiology at the Keck School of Medicine at the University of Southern California, Los Angeles. The study was published in the July 28 issue of the journal. Prior research has linked heart risk factors and mental decline, but this study focused on specific risk factors and three brain structures – the hippocampus, precuneus and posterior cingulate cortex – that play a role in memory. The ... Read more

Related support groups: Obesity, Smoking, Dementia, Smoking Cessation, Alzheimer's Disease, Alcohol Dependence, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

High Blood Sugar May Boost Alzheimer's Risk

Posted 1 day 9 hours ago by Drugs.com

MONDAY, July 27, 2015 – High blood sugar associated with prediabetes may increase the risk for Alzheimer's disease, a new study suggests. Researchers found that insulin resistance – higher-than-normal levels of blood sugar that often precede type 2 diabetes – was related to poorer performance on memory tests taken by late-middle-age adults. "The findings are interesting because people with diabetes are at increased risk for developing Alzheimer's disease, but we are only now learning why they may be at increased risk," said lead researcher Barbara Bendlin, an assistant professor of medicine at the University of Wisconsin-Madison. The study results suggest that insulin resistance could increase the risk for Alzheimer's disease by altering the way the brain uses sugar (glucose), which is its primary fuel, she said. However, "by altering insulin resistance in midlife, it may be possible ... Read more

Related support groups: Diabetes, Type 2, Insulin, Lantus, Alzheimer's Disease, Humalog, Novolog, Janumet, Lantus Solostar, Levemir, Pre-Diabetes, Novolin R, Novolin N, Humulin N, Lantus Solostar Pen, Humulin R, NovoLog FlexPen, ActoPlus Met, Humalog KwikPen, Apidra, Humalog Pen

Dementia Risk May Be Dropping With Generations

Posted 4 days ago by Drugs.com

FRIDAY, July 24, 2015 – New research suggests that people born after 1930 may have a lower risk of developing dementia than the generation before them, adding to evidence that the incidence of dementia may be declining in the United States and elsewhere. That decline was not explained by age, but did seem to be related to improvements in heart health over time, the researchers found. The study, of nearly 1,000 elderly New Yorkers, found that those born after 1930 had a lower risk of dementia than those born between 1916 and 1930. In the older group, people developed dementia at a rate of 2.2 percent per year between 1993 and 2014, when they were in their 70s and beyond, said lead researcher Carol Derby, an associate professor of neurology at the Albert Einstein College of Medicine, in New York City. In the younger group, that rate was just over 0.4 percent per year, Derby added. "We ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Cardiovascular Risk Reduction, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Exercise May Buffer Symptoms of Early Alzheimer's

Posted 5 days ago by Drugs.com

THURSDAY, July 23, 2015 – Regular exercise may be the best medicine for seniors facing the onset of dementia, according to three new clinical trials. Physical activity improved mood, memory and ability to think for participants in all three studies. One study found that intense aerobic exercise improves blood flow to key areas of the brain, and appears to reduce the tau protein tangles that are a hallmark of Alzheimer's disease. Alzheimer's is the most common form of dementia. "Blood flow decreases in those areas for all of us with age, and yet exercise increased it," said lead author Laura Baker, a cognitive neuroscientist at Wake Forest School of Medicine in Winston-Salem, N.C. "It seems to me we're changing aging-related effects, and we may be changing Alzheimer's-related effects, both with exercise." The new research was scheduled for presentation Thursday at the Alzheimer's ... Read more

Related support groups: Alzheimer's Disease

Hints That New Drug Solanezumab May Slow Alzheimer's Progression: Study

Posted 6 days ago by Drugs.com

WEDNESDAY, July 22, 2015 – A drug called solanezumab may slow Alzheimer's disease progression by about one-third, a new study from drug maker Eli Lilly suggests. An 18-month clinical trial of the drug seemingly ended in failure in 2012, but Eli Lilly asked about 1,000 of the patients in that trial with mild Alzheimer's to continue taking the drug for another two years. The results from that extension of the original trial suggest that solanazumab can significantly slow the progression of Alzheimer's among patients in the earliest stages of the disease, BBC News reported. The findings were presented at the Alzheimer's Association International Conference. The results of a separate clinical trial of solanazumab are expected next year. Current Alzheimer's drugs only help dying brain cells function, but the cells still eventually die. Solanazumab may be able to keep brain cells alive by ... Read more

Related support groups: Alzheimer's Disease

Women Descend Into Alzheimer's at Twice the Speed of Men: Study

Posted 7 days ago by Drugs.com

TUESDAY, July 21, 2015 – Women with mild thinking and memory problems – known as mild cognitive impairment – deteriorate twice as fast mentally as men with the same condition, according to new research. Mild cognitive impairment isn't severe enough to interfere with daily life, but it is linked to higher odds of developing Alzheimer's disease or another type of dementia, the researchers said. "Our findings do suggest greater vulnerability in women with mild cognitive impairment stage, which is more severe than normal memory loss and is an intermediary stage between aging and dementia," said lead researcher Katherine Lin, a clinical research scholar at Duke University in Durham, N.C. Several factors may account for this increased vulnerability among women, Lin added. Women may be genetically predisposed to developing more plaque in the brain, which is a hallmark of Alzheimer's, or ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Will Good Students Be Able to Sidestep Alzheimer's?

Posted 8 days ago by Drugs.com

MONDAY, July 20, 2015 – Kids at the head of the class not only have better college and job prospects, they may also stave off Alzheimer's disease, two new studies suggest. People with the best school grades and most complex jobs later on – as managers, teachers or executives, for example – have roughly a 40 to 60 percent reduced risk of developing dementia, according to two teams of Swedish researchers. But, both Swedish studies only found an association between school grades, later jobs and risks of dementia, and not a proven cause-and-effect link. "We are just starting to figure out that there is this lifetime risk for developing Alzheimer's disease," said Dean Hartley, director of science initiatives at the Alzheimer's Association, which played no part in either study. Part of reducing the risk for dementia is to build up what experts call "cognitive reserve," he said. Cognitive ... Read more

Related support groups: Alzheimer's Disease, Mild Cognitive Impairment

As Baby Boomers Age, Alzheimer's Rates Will Soar

Posted 8 days ago by Drugs.com

MONDAY, July 20, 2015 – The number of people with Alzheimer's disease is set to skyrocket in the United States due to the aging of the baby-boom generation, and the cost of caring for these patients will devour a large chunk of Medicare's budget, a new study suggests. More than 28 million baby boomers will develop Alzheimer's disease during the course of their lifetimes, the researchers estimated. By 2050, all baby boomers will be older than 85 and half of those still alive will suffer from Alzheimer's disease, said lead author Lisa Alecxih, senior vice president of The Lewin Group and director of the Lewin Center for Aging and Disability Policy. That's up from an estimated 1.2 percent prevalence of Alzheimer's among boomers in 2020, when most boomers will be in their 60s and early 70s, Alecxih said. Improvements in medical science are allowing people to live longer, but a long life is ... Read more

Related support groups: Alzheimer's Disease

Type 1 Diabetes Linked to Higher Risk of Dementia

Posted 8 days ago by Drugs.com

MONDAY, July 20, 2015 – People with type 1 diabetes may face a greater risk of developing thinking and memory problems as they age compared to the general population, new research suggests. The study found that people with type 1 diabetes were 83 percent more likely to develop dementia as seniors. "Our study found a modestly higher risk of all-cause dementia in people with type 1 diabetes. The next step is to figure out what that means, and how we can help people with type 1 diabetes age successfully," said study author Rachel Whitmer, a senior scientist in the division of research at Kaiser Permanente in Oakland, Calif. However, Whitmer also noted that the study doesn't prove that type 1 diabetes caused dementia, only that the two diseases were linked. "This is an observational study that shows association, not causation. We don't have tissue from these people's brains," she added. ... Read more

Related support groups: Insulin, Dementia, Diabetes, Type 1, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Diabetic Ketoacidosis (in DM Type I), Diabetic Coma (in DM Type I), Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia

Too Much TV, Too Little Exercise When Young May Hasten Mental Decline Later

Posted 8 days ago by Drugs.com

MONDAY, July 20, 2015 – Take heed, couch potatoes: Excessive TV time in young adulthood might raise your odds for mental decline decades later, a new study suggests. "Even early and mid-adulthood may be critical periods for promotion of physical activity" to help keep memory and thinking strong in old age, lead researcher Tina Hoang said in a news release from the Alzheimer's Association. Hoang, a research associate at the Northern California Institute of Research and Education in San Francisco, is slated to present her team's findings Monday at the annual meeting of the Alzheimer's Association, in Washington, D.C. Prior studies have suggested that physical activity later in life may help protect against mental decline, and possibly Alzheimer's disease and other types of dementia. However, Hoang's team said the effects of exercise in early adulthood on late-life mental health are much ... Read more

Related support groups: Alzheimer's Disease

Could a Saliva Test Help Spot Alzheimer's?

Posted 8 days ago by Drugs.com

SUNDAY, July 19, 2015 – It's still very early, but scientists say a test based on a patient's saliva might someday help detect Alzheimer's disease. "Saliva is easily obtained, safe and affordable, and has promising potential for predicting and tracking cognitive decline, but we're in the very early stages of this work and much more research is needed," study author Shraddha Sapkota, a neuroscience graduate student at the University of Alberta in Canada, said in a news release from the Alzheimer's Association. The study was to be presented Sunday at the Alzheimer's Association International Conference in Washington, D.C. Experts note that studies presented at medical meetings are typically considered preliminary until published in a peer-reviewed journal. In the study, Sapkota's team tested the saliva of 22 people with Alzheimer's disease, 25 people with what's known as mild cognitive ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation

Brain Changes Differ by Race With Alzheimer's Disease: Study

Posted 13 days ago by Drugs.com

WEDNESDAY, July 15, 2015 – Alzheimer's disease seems to develop differently in the brains of black patients than in whites. And, black people seem more likely to suffer different types of brain changes that also contribute to dementia, a new study reports. Alzheimer's disease dementia is generally associated with a build-up of substances known as plaques and tangles inside the brain. But, there are other brain changes that can also contribute to dementia, the study authors noted. For example, the brains of people with dementia sometimes contain infarcts – tiny areas of dead tissue caused by micro-strokes, the researchers explained. They also might contain Lewy bodies – another form of abnormal protein build-up in the brain that's usually associated with Parkinson's disease. Autopsies of black and white Alzheimer's patients revealed that blacks were more likely than whites to ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment

Human Brain Has Nearly Ideal Network of Connections, Research Shows

Posted 13 days ago by Drugs.com

WEDNESDAY, July 15, 2015 – A new study examining why the human brain evolved the way it did could lead to new ways to treat brain disorders, researchers say. The brain developed into its present form to speed transfer of information from one region of the brain to another, so people can perform at peak capacity, according to Dmitri Krioukov, an associate professor of physics at Northeastern University in Boston, and colleagues. The investigators found that the brain's structure contains an almost perfect network of connections. The researchers first created a map of a brain network that provided the best transfer of information between brain regions. They compared this "idealized" map with the brain's actual network and found that they were 89 percent similar. The study was published recently in the journal Nature Communications. Along with shedding new light on the brain's evolution, ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Brain Anomalies incl Congenital

Gene Linked to Alzheimer's May Affect Brain Early

Posted 13 days ago by Drugs.com

WEDNESDAY, July 15, 2015 – Neurologists have long known that a variant of a gene called APOEe4 can raise the odds for Alzheimer's disease in people who carry it. Now, new research suggests that the gene is already affecting the brain years before the onset of the illness. Researchers at Indiana University in Indianapolis looked at 600 older adults, including some who said that they had significant memory problems even though they showed normal results on standard thinking and memory tests. The researchers compared people with the APOEe4 gene variant against those with other, less harmful variants of the APOE gene. Based on tests, people who carried the APOEe4 variant had higher brain levels of amyloid plaque – those clumps of protein fragments that are commonly found in the brains of Alzheimer's patients. Their cerebrospinal fluid also had lower levels of a protein "precursor" to the ... Read more

Related support groups: Alzheimer's Disease

Uncontrolled Diabetes May Boost Dementia Risk

Posted 19 days ago by Drugs.com

THURSDAY, July 9, 2015 – Diabetes patients with high rates of complications from the disease may face increased risk for dementia, a new study suggests. "We found that as diabetes progresses and an individual experiences more complications from the disease, the risk of dementia rises as well," wrote Dr. Wei-Che Chiu, of the National Taiwan University College of Public Health, in Taipei. Better blood sugar control can help prevent the mental decline associated with diabetes, he and his colleagues said. They examined data from more than 431,000 people in Taiwan who were older than 50 and newly diagnosed with diabetes. Complications of diabetes include vision loss, kidney failure and nerve damage. Over 12 years of follow-up, more than 6 percent of the patients were diagnosed with dementia. Those with a greater number of diabetes complications were at higher risk for mental decline than ... Read more

Related support groups: Diabetes, Type 2, Peripheral Neuropathy, Dementia, Diabetes, Type 1, Alzheimer's Disease, Diabetic Neuropathy, Diabetic Nerve Damage, Pre-Diabetes, Diabetic Kidney Disease, Mild Cognitive Impairment, Diabetes Mellitus, Diabetic Nephropathy, Arteriosclerotic Dementia, Diabetic Retinopathy, Abnormal Glucose Tolerance, Lewy Body Dementia, Retinopathy Prophylaxis

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