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Alzheimer's Disease News

Related terms: Presenile Dementia, SDAT, Senile dementia Alzheimer's Type, Alzheimers

Alzheimer's-Linked Brain Plaques May Also Slow Blood Flow

Posted 1 day 13 hours ago by

TUESDAY, Nov. 24, 2015 – They've long been associated with Alzheimer's disease, and now new research in animals suggests that protein plaques might slow the brain's blood flow, as well. Buildup of the amyloid beta protein clumps could harm the brain in multiple ways, according to a team from the University of Alabama at Birmingham. "We have increasingly become aware that the disruption of blood flow in the brain can increase the risk of Alzheimer's disease," lead researcher Dr. Erik Roberson, an associate professor of neurology, said in a university news release. He explained that scientists have long known that protein plaques known as "vascular amyloid" can build up around blood vessels, just as they do in brain tissue. However, "we did not fully understand its effects," Roberson said. Now, high-tech imaging "allows us to visualize how it affects the function of those vessels," he ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation, Family History of Cerebrovascular Disease, Cerebrovascular Insufficiency

Alzheimer's-Linked Gene Tied to Brain Bleeds in Men: Study

Posted 8 days ago by

TUESDAY, Nov. 17, 2015 – Men who have the Alzheimer's disease-linked ApoE4 gene variant may have an increased risk for brain bleeds, a new study suggests. Researchers analyzed brain scans of more than 1,100 people, ages 36 to 91, in the United States, Canada and Sweden. Some were healthy, some had mild thinking and memory problems, and some had Alzheimer's disease. Among participants with ApoE4 and mild cognitive impairment or Alzheimer's disease, men had twice as many tiny brain bleeds (microbleeds) as women, according to the study published online recently in the journal Neurobiology of Aging. Microbleeds cause small areas of damage throughout the brain and contribute to memory loss, said study corresponding author Caleb Finch, a professor at the University of Southern California's Davis School of Gerontology. The finding is surprising, the researchers reported, because women with ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation, Intracranial Hemorrhage

Coffee Drinkers May Live Longer

Posted 9 days ago by

MONDAY, Nov. 16, 2015 – Coffee lovers may live longer than those who don't imbibe – with lower risks of early death from heart disease and neurological conditions such as Parkinson's disease, a large U.S. study finds. Researchers said the study, published online Nov. 16 in Circulation, adds to a large body of evidence on the good side of coffee. People often think of coffee-drinking as a bad habit that they need to break, said study leader Dr. Frank Hu, a professor of nutrition and epidemiology at Harvard School of Public Health in Boston. But, Hu said, many studies have linked moderate coffee intake to lower risks of developing various diseases – from heart disease and diabetes, to liver cancer, to neurological diseases such as Parkinson's, multiple sclerosis and Alzheimer's. His team's study, funded by the U.S. National Institutes of Health, adds another layer of evidence. It found ... Read more

Related support groups: Multiple Sclerosis, Parkinson's Disease, Caffeine, Alzheimer's Disease, Fioricet, Excedrin, Alert, Fiorinal, Cafergot, Excedrin Migraine, Esgic, Fiorinal with Codeine, Fioricet with Codeine, Norgesic, Esgic-Plus, Excedrin Extra Strength, Keep Going, Dolgic Plus, Headache Relief, Norgesic Forte

Failing Sense of Smell Might Be Alzheimer's Warning

Posted 10 days ago by

MONDAY, Nov. 16, 2015 – Losing your sense of smell may mark the start of memory problems and possibly Alzheimer's disease, a new study suggests. Researchers found that older adults who had the worst smell test scores were 2.2 times more likely to begin having mild memory problems. And if they already had these memory problems, they were more likely to progress to full-blown Alzheimer's disease, said lead researcher Rosebud Roberts, a professor of neurology at the Mayo Clinic in Rochester, Minn. "The findings suggest that doing a smell test may help identify elderly, mentally normal people who are likely to progress to develop memory problems or, if they have these problems, to progress to Alzheimer's dementia," Roberts said. "Physicians need to recognize that this may be a possible screening tool that can be used in the clinic," she added. But Roberts also cautioned that the findings ... Read more

Related support groups: Alzheimer's Disease, Mild Cognitive Impairment

Physical Fitness Linked to Mental Fitness in Seniors

Posted 13 days ago by

THURSDAY, Nov. 12, 2015 – Connections between different parts of the brain weaken with age, but new research suggests that being physically fit can boost long-term brain function. A study from the University of Illinois at Urbana-Champaign found that age-related differences in the brains of older adults varied, depending on their level of aerobic endurance. The researchers found greater fitness is associated with stronger brain connections later in life. However, the study did not prove a cause-and-effect relationship between the two. "Our study provides the strongest evidence to date that fitness in an older adult population can have substantial benefits to brain health in terms of the functional connections of different regions of the brain," Arthur Kramer, director of the Beckman Institute, said in a university news release. The study involved both younger and older adults. Using ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Hormone-Like Drug Doesn't Help Women With Alzheimer's: Study

Posted 4 Nov 2015 by

WEDNESDAY, Nov. 4, 2015 – The drug raloxifene doesn't help the declining memory and thinking skills of women who have mild to moderate dementia due to Alzheimer's disease, a small study suggests. "We found no effect," said study researcher Dr. Victor Henderson, professor of health research and policy and neurology and neurological sciences at Stanford University in California. Raloxifene is a complex drug. It acts like the female hormone estrogen in some parts of the body, while it blocks the effects of estrogen in the breasts and uterus, the study authors explained. The researchers decided to look at the drug after another study of raloxifene, which is also used to treat the bone-thinning disease osteoporosis, found that the drug reduced the risk of healthy women developing impairments in their thinking and memory, Henderson said. The new study, published online Nov. 4 in Neurology, ... Read more

Related support groups: Dementia, Alzheimer's Disease, Evista, Mild Cognitive Impairment, Raloxifene

Feeling Extra Forgetful May Signal Dementia Ahead

Posted 28 Oct 2015 by

WEDNESDAY, Oct. 28, 2015 – For some older women, feeling unusually forgetful may be a sign that dementia will develop later on, a new study suggests. "We studied older women who noticed themselves having memory problems but who still performed normally on a standard test," said Allison Kaup, an assistant professor of psychiatry at the University of California, San Francisco School of Medicine. "These findings raise the possibility that memory complaints in older adults may be a very early symptom of a memory disorder that is just starting to gradually develop." But Kaup stressed that common memory problems, such as forgetting names, do not indicate that a person will definitely develop dementia. For the study, published online Oct. 28 in the journal Neurology, researchers tracked more than 1,100 women 65 and older who had normal brain function when the study began. Over the next 18 ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

End-of-Life Care for Dementia Much Pricier Than for Other Ills

Posted 26 Oct 2015 by

MONDAY, Oct. 26, 2015 – Health care and caregiving costs for dementia patients in the final five years of life are far more burdensome than they are for patients with cancer, heart disease and other illnesses, a new study suggests. The study found that total "social costs" – such as government spending, private insurance and out-of-pocket expenditures for dementia patients – were 57 percent greater than costs associated with death from other conditions. "The magnitude of the difference was shocking to me, even though the trend is what I expected," said study author Dr. Amy Kelley, an associate professor of geriatrics and palliative medicine at Icahn School of Medicine at Mount Sinai in New York City. "I don't think the vast majority of people have any idea about these costs unless they're living it." The study findings were published online Oct. 26 in the Annals of Internal Medicine. ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Celiac Disease Doesn't Seem to Boost Dementia Risk: Study

Posted 23 Oct 2015 by

FRIDAY, Oct. 23, 2015 – Having celiac disease does not appear to increase your risk of dementia, a new study finds. Researchers looked at more than 8,800 people older than 50. After a median period of about eight years, 4.3 percent of celiac patients and 4.4 percent of those without the digestive disease were diagnosed with dementia. "Celiac disease did not increase the risk of Alzheimer's in this population-based study," said study lead author Dr. Benjamin Lebwohl, assistant professor of medicine and epidemiology at Columbia University Medical Center in New York City. "We did not find evidence of increased dementia risk prior to the diagnosis of celiac disease, either," he said in a hospital news release. Researchers did find a slight increase, however, in celiac patients' risk of developing vascular dementia. The second-leading cause of dementia after Alzheimer's disease, vascular ... Read more

Related support groups: Dementia, Alzheimer's Disease, Celiac Disease, Mild Cognitive Impairment, Lewy Body Dementia

Brain Differences Seen in Young Adults at Genetic Risk of Alzheimer's

Posted 22 Oct 2015 by

THURSDAY, Oct. 22, 2015 – Young adults who have an increased genetic risk for Alzheimer's disease may already show differences in how their brains handle spatial navigation, a small study suggests. The researchers said it's too soon to know whether the brain differences are a harbinger of Alzheimer's. "That is still unclear and needs to be investigated in further studies," said senior researcher Dr. Nikolai Axmacher, of the German Center for Neurodegenerative Diseases, in Bonn. But the hope, he said, is that the findings will improve researchers' understanding of the earliest processes that lead to Alzheimer's – the most common form of dementia. And if the brain differences do turn out to predict Alzheimer's disease years later, that information could be used to pinpoint high-risk people early, Axmacher added. Other researchers said the findings were important, because everyone wants ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation

Researchers Move Closer to Alzheimer's Blood Test

Posted 19 Oct 2015 by

MONDAY, Oct. 19, 2015 – Researchers say they have moved closer to developing a blood test for Alzheimer's disease. Such a test would enable doctors to diagnose patients at the earliest, most treatable stage so patients could make lifestyle changes that may slow progression of the brain disease, reported the team at the Rowan University School of Osteopathic Medicine in Stratford, N.J. "There are significant benefits to early disease detection because we now know that many of the same conditions that lead to vascular disease are also significant risk factors for Alzheimer's," lead researcher Robert Nagele said in an association news release. The scientists focused on use of autoantibodies in the blood as biomarkers for the presence and stage of Alzheimer's disease. Autoantibodies are immune proteins that mistakenly attack the body's own cells. The findings were presented Sunday at an ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation

Nerve Disorder in Horses May Offer Clues to Alzheimer's

Posted 16 Oct 2015 by

FRIDAY, Oct. 16, 2015 – Some signs of a rare nerve disorder in horses are similar to those in people with Alzheimer's disease and other brain disorders, a new study shows. The deadly disease in horses – called equine grass sickness – could offer clues about the human conditions, according to the researchers at the University of Edinburgh in Scotland. "This is the first study to show similarities between an apparently unrelated neurodegenerative disease of large animals and human neurological conditions," said study author Dr. Thomas Wishart. "Although the causes of these conditions are unlikely to be shared, the findings suggest that similar mechanisms could be involved in the later stages of disease." The causes of grass sickness, which attacks nerve cells and leads to stomach problems and muscle tremor, are unknown. The investigators analyzed nerve tissue from six horses killed by ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation

Weight, Growth Early in Life May Affect Adult Brain

Posted 9 Oct 2015 by

FRIDAY, Oct. 9, 2015 – Birth weight and growth during childhood could affect hearing, vision, thinking and memory later in life, a new study suggests. "Sensory problems and illness such as dementia are an increasing problem, but these findings suggest that issues begin to develop right from early life," said the study's leader, Dr. Piers Dawes. He is a lecturer in audiology at the University of Manchester's School of Psychological Sciences in England. "While interventions in adulthood may only have a small effect, concentrating on making small improvements to birth size and child development could have a much greater impact on numbers of people with hearing, vision and cognitive [mental] impairment," Dawes said in a university news release. However, the study findings don't mean that parents of children who don't physically match their average-sized peers at birth or as they're growing ... Read more

Related support groups: Obesity, Eye Conditions, Weight Loss, Dementia, Alzheimer's Disease, Macular Degeneration, Mild Cognitive Impairment, Hearing Loss, Prematurity/Underweight in Infancy

Depression Adds to Burden of Alzheimer's Caregivers, Study Finds

Posted 1 Oct 2015 by

THURSDAY, Oct. 1, 2015 – Depression increases the mental strain on people caring for loved ones recently diagnosed with Alzheimer's disease, a new study finds. The study included spouses and other family caregivers of 236 people in Finland who were diagnosed with very mild or mild Alzheimer's disease. The caregivers were followed for three years after their loved ones were diagnosed. The highest levels of mental stress occurred in caregivers who had depression when their loved one was diagnosed with Alzheimer's, the investigators found. "The occurrence of even mild depressive symptoms predicted a psychological load on the family caregiver irrespective of, for example, the progression of the disease," study author Tarja Valimaki said in a University of Eastern Finland news release. Valimaki is a clinical researcher in the university's department of nursing science. The researchers also ... Read more

Related support groups: Depression, Major Depressive Disorder, Alzheimer's Disease, Dysthymia, Seasonal Affective Disorder

Finding Disease Cures Can Take Up to a Century: Analysis

Posted 24 Sep 2015 by

THURSDAY, Sept. 24, 2015 – A team of scientists has looked back over decades of discovery to conclude that it can take dozens of years, even a century, for cumulative research to lead to a cure for a single disease. The finding is disheartening given the current U.S. government underfunding of the basic science needed to investigate diseases, said a team led by Dr. R. Sanders Williams, president of the San Francisco-based Gladstone Institutes, a biomedical research organization. "As shown by our analysis, new treatments depend upon a broad base of scientific knowledge plus special contributions from a few exceptional scientists," Williams said in an institute news release. For anyone suffering from an illness, the dream word is "cure." True cures for disease remain rare, though. But, in the new study the Gladstone team traced the long investigative paths linking generations of ... Read more

Related support groups: Diabetes, Type 2, Cancer, Parkinson's Disease, Heart Failure, Congestive Heart Failure, Diabetes, Type 1, Alzheimer's Disease, Diabetes Mellitus, Diagnosis and Investigation, Parkinsonism, Yervoy, Ipilimumab, Orkambi, Kalydeco, Ivacaftor/lumacaftor, Ivacaftor

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