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Related terms: Presenile Dementia, SDAT, Senile dementia Alzheimer's Type, Alzheimers

Type 2 Diabetes Linked to More Alzheimer's Brain 'Tangles'

Posted 1 day 20 hours ago by Drugs.com

WEDNESDAY, Sept. 2, 2015 – People with type 2 diabetes may be more prone to developing the brain "tangles" associated with Alzheimer's disease, a new study suggests. The study found that people with type 2 diabetes had a greater accumulation of brain tangles – even if they were free of dementia or milder problems with memory and thinking. The findings, reported Sept. 2 in the journal Neurology, hint at one explanation for why people with type 2 diabetes have an increased risk of Alzheimer's disease. That is, type 2 diabetes may cause brain abnormalities that pile on to other degenerative changes that ultimately lead to dementia, explained study senior researcher Dr. Velandai Srikanth, a geriatrician at Monash University in Melbourne, Australia. However, he said, this study shows only a correlation between type 2 diabetes and brain tangles. It's not clear whether the type 2 diabetes is ... Read more

Related support groups: Diabetes, Type 2, Ischemic Stroke, Alzheimer's Disease

Too Much Weight in Middle Age Tied to Earlier Alzheimer's

Posted 2 days 22 hours ago by Drugs.com

TUESDAY, Sept. 1, 2015 – Avoiding middle-age spread could be one way to delay the onset of dementia, a new study hints. Researchers found that among 142 elderly adults with Alzheimer's disease, those who were overweight at age 50 tended to develop the memory-robbing disorder earlier. On average, the study participants were 83 years old when diagnosed with Alzheimer's. But that age of onset varied according to people's weight at age 50: For each unit increase in body mass index (BMI), Alzheimer's set in about seven months earlier, on average. Other studies have found that obesity may boost the risk of developing Alzheimer's. But this research suggests it also speeds the onset, said senior researcher Dr. Madhav Thambisetty, of the U.S. National Institute on Aging. "We think that's important because one of the goals in Alzheimer's research is to find ways to delay the onset of the ... Read more

Related support groups: Obesity, Weight Loss, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Awareness of Memory Problems Fades a Few Years Before Dementia: Study

Posted 9 days ago by Drugs.com

WEDNESDAY, Aug. 26, 2015 – Older adults destined to develop dementia may start to lose awareness of their memory problems two to three years before the disease is full blown, a new study finds. That had been suspected, but not clearly shown before, said lead investigator Robert Wilson, senior neuropsychologist at the Rush Alzheimer's Disease Center in Chicago. "As researchers, we're very interested in what the experience of dementia is like for the individual," Wilson said. "It's important to understand its natural progression." The findings also offer some useful information for the average person, according to Wilson. "If you're aware enough to be worried about your memory, you probably don't have dementia," he said. Nor is it clear that you ever will, since memory issues do not mean a person is doomed to develop Alzheimer's or other forms of dementia. The findings, published in the ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Exercise, Supplements Like Fish Oil Won't Keep Elderly Sharper: Studies

Posted 10 days ago by Drugs.com

TUESDAY, Aug. 25, 2015 – Neither exercise nor supplements such as fish oil don't seem to do much to help keep older folks mentally sharp, two new studies found. The reports, published Aug. 25 in the Journal of the American Medical Association, cast doubts on two strategies purported to keep older brains younger and healthier. In one study, two years' worth of moderate exercise didn't seem to improve the brain power of people between 70 and 89 or lower their odds for dementia. Similarly, giving older adults fish oil or other supposed brain nutrients did not keep them sharper. The exercise study, which involved 1,600 sedentary adults, "is the largest and longest randomized trial of a physical activity intervention in older adults who were not already active and were at risk of losing their ability to walk," said Dr. Kaycee Sink, medical director of the Kulynych Memory Assessment Clinic ... Read more

Related support groups: Dementia, Dietary Supplementation, Alzheimer's Disease, Fish Oil, Lovaza, Mild Cognitive Impairment, Omega-3, Arteriosclerotic Dementia, Omacor, Omega-3 Polyunsaturated Fatty Acids, MaxEPA, Marine Lipid Concentrate, Animi-3, Lewy Body Dementia, Super-EPA, Omega 3-6-9 Complex, Mi-Omega, Doxycycline/Omega-3 Polyunsaturated Fatty Acids, MegaKrill, Omega-500

9 Factors You Can Control May Be Key to Alzheimer's Risk

Posted 14 days ago by Drugs.com

THURSDAY, Aug. 20, 2015 – Up to two-thirds of Alzheimer's cases worldwide may stem from any of nine conditions that often result from lifestyle choices, a broad research review suggests. Those include obesity (specifically, high body mass index, an indication of obesity, in midlife); carotid artery disease, in which plaque buildup narrows major neck arteries and slows blood supply to the brain; high blood pressure; depression; being frail; being poorly educated; having high levels of a naturally occurring amino acid known as homocysteine; and (specifically among those of Asian descent) being a smoker and/or having either type 2 diabetes. The implication: Taking steps to minimize or eliminate such conditions might reduce the long-term risk for developing Alzheimer's, a brain disorder that affects memory and thinking. It is the most common form of dementia among seniors. "The current ... Read more

Related support groups: Depression, High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Smoking, Major Depressive Disorder, Alzheimer's Disease, Dysthymia, Coronary Artery Disease (CAD), Hypertensive Heart Disease

Why the Aging Brain Is More Vulnerable to Alzheimer's

Posted 15 days ago by Drugs.com

THURSDAY, Aug. 20, 2015 – Age is the greatest risk factor for Alzheimer's disease, and researchers now think they know why that's the case. New cutting-edge technology reveals that as you age, your brain becomes less and less capable of flushing away a toxic waste product of brain activity called beta-amyloid, the researchers said. Beta-amyloid proteins can clump together, forming larger amyloid plaques in the spaces between neurons. These amyloid plaques are a hallmark of Alzheimer's disease, the most common form of dementia. "This is a clue as to why age is the number one, two and three risk factor for Alzheimer's disease," said study senior author Dr. Randall Bateman, director of the Dominantly Inherited Alzheimer Network Trials Unit at the Washington University School of Medicine in St. Louis. "As we slow down our ability to clear away these sticky proteins, the risk of having ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Type 2 Diabetes Linked to Language Problems in Women

Posted 13 Aug 2015 by Drugs.com

THURSDAY, Aug. 13, 2015 – Insulin resistance, a key component of type 2 diabetes, may contribute to language problems in women that can potentially signal early dementia, new research suggests. The association was not seen in men, although the researchers could not determine exactly why that was so. In the study, the Finnish researchers measured what is called low verbal fluency, which is the rate at which you produce words. "Preclinical Alzheimer's disease typically starts with episodic memory decline. However, verbal fluency is a measure of executive function, and also deficits in executive function can be found early in the disease," said study author Dr. Laura Ekblad, a researcher at the University of Turku. Executive function includes higher-order processes such as working memory, planning and problem solving. But Ekblad added that the findings aren't cause for immediate concern ... Read more

Related support groups: Diabetes, Type 2, Insulin, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Kidney Problems Linked to Brain Disorders: Study

Posted 6 Aug 2015 by Drugs.com

THURSDAY, Aug. 6, 2015 – Kidney problems can increase the risk of brain disorders, a new study finds. The findings suggest that protecting kidney health may also benefit the brain, the researchers said. They studied data from more than 2,600 people in the Netherlands, and found that poor kidney function was strongly associated with decreased blood flow to the brain. They also saw an increased risk of stroke and memory and thinking problems (dementia) in people with kidney problems. The association was independent of known heart disease risk factors, the researchers said. The study was published Aug. 6 in the Journal of the American Society of Nephrology. "Our findings provide a possible explanation linking kidney disease to brain disease," Dr. M. Arfan Ikram, an assistant professor of neuroepidemiology at Erasmus University Medical Center in the Netherlands, said in a journal news ... Read more

Related support groups: Dementia, Renal Failure, Alzheimer's Disease, Kidney Infections, Chronic Kidney Disease, Diabetic Kidney Disease, Mild Cognitive Impairment, Peritoneal dialysis, Diabetic Nephropathy, Anemia Associated with Chronic Renal Failure, Polycystic Kidney Disease, Pyelonephritis, Renal Osteodystrophy, Hyperphosphatemia of Renal Failure, Renal Vein Thrombosis, Lewy Body Dementia, Renal and Genitourinary Disorders, Renovascular Hypertension

Dementia Meds May Lead to Harmful Weight Loss: Study

Posted 3 Aug 2015 by Drugs.com

MONDAY, Aug. 3, 2015 – A class of drugs widely used to treat dementia – called cholinesterase inhibitors – could cause harmful weight loss in some patients, a new study suggests. These medications include Aricept (donepezil), Razadyne (galantamine) and Exelon (rivastigmine). "Our study provides evidence in a large, real-world population that cholinesterase inhibitors may contribute to clinically significant weight loss in a substantial proportion of older adults with dementia," study lead author Dr. Meera Sheffrin, a geriatrics fellow in the School of Medicine, at the University of California, San Francisco, said in a university news release. One expert said the findings point out a common problem for Alzheimer's patients. "Weight loss is a concern, not only for patients but also for their overwhelmed caregivers, who keep struggling with multiple challenges, including providing their ... Read more

Related support groups: Weight Loss, Dementia, Alzheimer's Disease, Aricept, Donepezil, Exelon, Mild Cognitive Impairment, Galantamine, Arteriosclerotic Dementia, Rivastigmine, Reminyl, Razadyne, Cachexia, Razadyne ER, Namzaric, Tacrine, Cognex, Aricept ODT, Lewy Body Dementia, Donepezil/memantine

Regular, Moderate Coffee Drinking Tied to Better Brain Health in Seniors

Posted 31 Jul 2015 by Drugs.com

FRIDAY, July 31, 2015 – A study of more than 1,400 Italian seniors finds links between patterns of coffee consumption and their risk for "mild cognitive impairment" – declines in memory and thinking that are often a precursor to dementia. The study could only point to associations, not cause-and-effect, the investigators said. But prior research has suggested that caffeine might impact neurological health. In the study, a team led by Dr. Vincenzo Solfrizzi of the University of Bari Aldo Moro, looked at the coffee consumption of 1,445 Italians aged 65 to 84. The participants' mental health was also tracked for a median of three-and-a-half years. Reporting earlier this week in the Journal of Alzheimer's Disease, the research team found that people who consistently drank about one or two cups of coffee per day had a lower rate of mild cognitive impairment (MCI) than those who never or ... Read more

Related support groups: Dementia, Caffeine, Fioricet, Alzheimer's Disease, Excedrin, Alert, Fiorinal, Mild Cognitive Impairment, Cafergot, Excedrin Migraine, Esgic, Esgic-Plus, Fioricet with Codeine, Fiorinal with Codeine, Norgesic, Acetaminophen/Butalbital/Caffeine, Excedrin Extra Strength, Trezix, Dolgic Plus, Headache Relief

Heart Disease, Alzheimer's Linked by Common Risk Factors

Posted 28 Jul 2015 by Drugs.com

TUESDAY, July 28, 2015 – Some risk factors for heart disease may also be linked with Alzheimer's and other types of dementia, a new study reports. "We already know that vascular risk factors damage the brain and can result in cognitive [mental] impairment," study lead author Dr. Kevin King said in a news release from the journal Radiology. "Our findings give us a more concrete idea about the relationship between specific vascular risk factors and brain health," said King, an assistant professor of radiology at the Keck School of Medicine at the University of Southern California, Los Angeles. The study was published in the July 28 issue of the journal. Prior research has linked heart risk factors and mental decline, but this study focused on specific risk factors and three brain structures – the hippocampus, precuneus and posterior cingulate cortex – that play a role in memory. The ... Read more

Related support groups: Obesity, Smoking, Dementia, Smoking Cessation, Alzheimer's Disease, Alcohol Dependence, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

High Blood Sugar May Boost Alzheimer's Risk

Posted 27 Jul 2015 by Drugs.com

MONDAY, July 27, 2015 – High blood sugar associated with prediabetes may increase the risk for Alzheimer's disease, a new study suggests. Researchers found that insulin resistance – higher-than-normal levels of blood sugar that often precede type 2 diabetes – was related to poorer performance on memory tests taken by late-middle-age adults. "The findings are interesting because people with diabetes are at increased risk for developing Alzheimer's disease, but we are only now learning why they may be at increased risk," said lead researcher Barbara Bendlin, an assistant professor of medicine at the University of Wisconsin-Madison. The study results suggest that insulin resistance could increase the risk for Alzheimer's disease by altering the way the brain uses sugar (glucose), which is its primary fuel, she said. However, "by altering insulin resistance in midlife, it may be possible ... Read more

Related support groups: Diabetes, Type 2, Insulin, Lantus, Alzheimer's Disease, Novolog, Humalog, Janumet, Lantus Solostar, Levemir, Pre-Diabetes, Novolin R, Novolin N, Humulin N, Lantus Solostar Pen, Humulin R, NovoLog FlexPen, ActoPlus Met, Humalog KwikPen, Apidra, Humalog Pen

Dementia Risk May Be Dropping With Generations

Posted 24 Jul 2015 by Drugs.com

FRIDAY, July 24, 2015 – New research suggests that people born after 1930 may have a lower risk of developing dementia than the generation before them, adding to evidence that the incidence of dementia may be declining in the United States and elsewhere. That decline was not explained by age, but did seem to be related to improvements in heart health over time, the researchers found. The study, of nearly 1,000 elderly New Yorkers, found that those born after 1930 had a lower risk of dementia than those born between 1916 and 1930. In the older group, people developed dementia at a rate of 2.2 percent per year between 1993 and 2014, when they were in their 70s and beyond, said lead researcher Carol Derby, an associate professor of neurology at the Albert Einstein College of Medicine, in New York City. In the younger group, that rate was just over 0.4 percent per year, Derby added. "We ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Cardiovascular Risk Reduction, Lewy Body Dementia, Arteriosclerotic Dementia w/ Depressive Features

Exercise May Buffer Symptoms of Early Alzheimer's

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Regular exercise may be the best medicine for seniors facing the onset of dementia, according to three new clinical trials. Physical activity improved mood, memory and ability to think for participants in all three studies. One study found that intense aerobic exercise improves blood flow to key areas of the brain, and appears to reduce the tau protein tangles that are a hallmark of Alzheimer's disease. Alzheimer's is the most common form of dementia. "Blood flow decreases in those areas for all of us with age, and yet exercise increased it," said lead author Laura Baker, a cognitive neuroscientist at Wake Forest School of Medicine in Winston-Salem, N.C. "It seems to me we're changing aging-related effects, and we may be changing Alzheimer's-related effects, both with exercise." The new research was scheduled for presentation Thursday at the Alzheimer's ... Read more

Related support groups: Alzheimer's Disease

Hints That New Drug Solanezumab May Slow Alzheimer's Progression: Study

Posted 22 Jul 2015 by Drugs.com

WEDNESDAY, July 22, 2015 – A drug called solanezumab may slow Alzheimer's disease progression by about one-third, a new study from drug maker Eli Lilly suggests. An 18-month clinical trial of the drug seemingly ended in failure in 2012, but Eli Lilly asked about 1,000 of the patients in that trial with mild Alzheimer's to continue taking the drug for another two years. The results from that extension of the original trial suggest that solanazumab can significantly slow the progression of Alzheimer's among patients in the earliest stages of the disease, BBC News reported. The findings were presented at the Alzheimer's Association International Conference. The results of a separate clinical trial of solanazumab are expected next year. Current Alzheimer's drugs only help dying brain cells function, but the cells still eventually die. Solanazumab may be able to keep brain cells alive by ... Read more

Related support groups: Alzheimer's Disease

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Namenda, Aricept, donepezil, Exelon, vitamin e, Namenda XR, memantine, galantamine, rivastigmine, view more... Reminyl, etanercept, Hydergine, Axona, Razadyne, Razadyne ER, Namzaric, Aquasol E, Alpha E, Gerimal, Hydergine LC, E-600, Aqua Gem-E, Aqua-E, E-Gems, E Pherol, Aricept ODT, donepezil / memantine, caprylidene, ergoloid mesylates, Amino-Opti-E, Vita-Plus E Natural, Centrum Singles-Vitamin E, E-400 Clear, Nutr-E-Sol, Aquavite-E