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Alzheimer's Disease Blog

Related terms: Presenile Dementia, SDAT, Senile dementia Alzheimer's Type, Alzheimers

Could a Diet Help Shield You From Alzheimer's?

Posted 1 day 5 hours ago by Drugs.com

FRIDAY, March 27, 2015 – Scientists say they've developed an anti-Alzheimer's diet. While it couldn't prove cause-and-effect, the new study found that adults who rigorously followed the so-called MIND diet faced a 53 percent lower risk for Alzheimer's, the most common type of dementia. Those sticking to the diet just "moderately well" saw their Alzheimer's risk drop by roughly 35 percent. "Often, people who eat healthier also participate in other healthy lifestyle behavior, but the MIND diet afforded protection [against Alzheimer's] whether or not other healthy behaviors or health conditions were present," said study author Martha Clare Morris, a nutritional epidemiologist at the Rush University Medical Center and the Rush Alzheimer's Disease Center in Chicago. The eating plan emphasizes healthy grains, vegetables, beans, poultry and fish while also allowing for a limited amount of ... Read more

Related support groups: Alzheimer's Disease

Many With Alzheimer's Aren't Told of Diagnosis by Doctor: Report

Posted 4 days ago by Drugs.com

TUESDAY, March 24, 2015 – Doctors are not telling a majority of their patients diagnosed with Alzheimer's that they have the degenerative brain disease, a new report shows. The research, conducted by the Alzheimer's Association, involved patients whose Medicare records listed treatments that are specific to Alzheimer's disease. However, when the researchers asked the patients (or a caregiver as a proxy) if their doctor had informed them that they had the brain-robbing disease, only 45 percent said they had been told so by their doctor. By comparison, more than 90 percent of people with the four most common cancers – breast, colorectal, lung and prostate – said they had been told about their diagnosis. "These really low diagnosis disclosure rates [of Alzheimer's] are really reminiscent of what happened in the 1950s and '60s, and even into the '70s, with cancer," said Beth Kallmyer, ... Read more

Related support groups: Alzheimer's Disease, Diagnosis and Investigation

Researchers Pinpoint Possible Protein Culprit Behind Alzheimer's

Posted 4 days ago by Drugs.com

TUESDAY, March 24, 2015 – Abnormal tau protein collecting in the brain may be the main cause of Alzheimer's disease, a new study claims. Another protein called amyloid accumulates as Alzheimer's progresses, but is not the primary culprit behind the devastating memory loss that is the hallmark of the disease, Mayo Clinic researchers report. They said their findings suggest that targeting tau should be the new focus of efforts to find treatments for Alzheimer's. "The majority of the Alzheimer's research field has really focused on amyloid over the last 25 years," study author Melissa Murray, a neuroscientist at the Mayo Clinic in Jacksonville, Fla., said in a Mayo news release. The researchers analyzed 1,375 brains of deceased Alzheimer's patients in the Mayo Clinic's brain bank. The patients died at different ages and at different stages of Alzheimer's, providing a timeline for disease ... Read more

Related support groups: Alzheimer's Disease

Antipsychotics May Be Deadlier Than Thought for Dementia Patients

Posted 10 days ago by Drugs.com

WEDNESDAY, March 18, 2015 – Antipsychotic drugs may increase the risk of premature death in dementia patients more than thought, a new study suggests. The medications are widely used to treat the delusions, hallucinations, agitation and aggression that occur in many people with Alzheimer's disease and other types of dementia. However, the U.S. Food and Drug Administration warns that antipsychotic drugs have a significant risk of side effects, the study authors pointed out. For the new study, researchers examined data from nearly 91,000 U.S. veterans who were older than 65 and had dementia. Those who took antipsychotics were more likely to die early, the study found. Among those taking newer, more commonly used antipsychotics, the risk of premature death increased with the dose. "The harms associated with using these drugs in dementia patients are clear, yet clinicians continue to use ... Read more

Related support groups: Dementia, Alzheimer's Disease

Age-Linked Memory Loss May Be Worse for Men, Study Finds

Posted 12 days ago by Drugs.com

MONDAY, March 16, 2015 – Can't remember that work colleague's name? Misplaced your keys again? Don't fret: a new study finds that nearly everyone will suffer more memory lapses as they age, with men being more vulnerable to failing memory than women. The study also reported that people's memory skills and brain volume typically decline with age – and, surprisingly, it seems to have little to do with the buildup of brain "plaques" that mark Alzheimer's disease, the study suggests. The researchers said their findings challenge a prevailing view on the aging brain. Experts have speculated that when older adults start having memory lapses, it may be a sign of early Alzheimer's disease – and likely related to abnormal clumps of a protein called beta-amyloid that accumulate in the brain. "But our findings suggest that memory actually declines in almost everybody, and well before there is ... Read more

Related support groups: Alzheimer's Disease, Mild Cognitive Impairment, Diagnosis and Investigation

Healthy Lifestyle May Guard Against Dementia

Posted 17 days ago by Drugs.com

WEDNESDAY, March 11, 2015 – A healthy diet, physical activity and brain exercises can help slow mental decline in older people at risk for dementia, a new study suggests. On the other hand, a high body-mass index (BMI) and poor heart health are significant risk factors for age-related dementia, the researchers said. BMI is an estimate of body fat based on height and weight. The study included 1,260 people in Finland, aged 60 to 77, who were considered to be at high risk for dementia. They were randomly selected to receive either regular health advice (the control group) or to be part of an intervention group. Over two years, those in the intervention group met regularly with doctors, nurses and other health professionals who provided advice on healthy eating, strength and heart-healthy exercise, brain training programs and management of metabolic and circulatory risk factors for ... Read more

Related support groups: Obesity, Dementia, Alzheimer's Disease, Mild Cognitive Impairment

Ultrasound Used to Attack Alzheimer's-Linked Brain Plaque in Mice

Posted 17 days ago by Drugs.com

WEDNESDAY, March 11, 2015 – Preliminary research in mice raises the possibility that an ultrasound-based treatment might help eliminate plaque buildup in the brain that's associated with Alzheimer's disease. Scientists don't know whether the approach is feasible for humans, but the research is promising, especially because of how well mice with an Alzheimer's-like disease fared after treatment, said study lead author Gerhard Leinenga, a graduate student at the University of Queensland in Australia. "The mice performed better on three tests of their memory," Leinenga said, noting their performance was similar to that of healthy mice used as controls. The ultrasound treatment targets brain-clogging material known as amyloid plaque. Scientists suspect plaque is connected to the development of Alzheimer's disease – a progressive brain disorder – but its exact role is unclear. "We know ... Read more

Related support groups: Alzheimer's Disease

Exercise's Effect on Brain May Boost Mobility in Old Age

Posted 17 days ago by Drugs.com

WEDNESDAY, March 11, 2015 – Staying physically active as you age may ward off brain damage that can limit mobility, a small study says. Small areas of brain damage called white matter hyperintensities are seen in MRI scans of many older patients, according to scientists from Rush University Medical Center in Chicago. Higher levels of this damage have been linked to difficulty walking and other mobility problems, the researchers said. "Preserving motor function is just as important as preserving mental function to maintain independence and quality of life in older age," said lead researcher Debra Fleischman, a professor in the departments of neurological sciences and behavioral sciences. "Our results suggest that daily physical activity may be able to protect motor function from age-related injury to the brain," she added. The study, published March 11 online in the journal Neurology, ... Read more

Related support groups: Dementia, Alzheimer's Disease

Good Heart Health May Help Stave Off Dementia, Study Says

Posted 18 days ago by Drugs.com

TUESDAY, March 10, 2015 – Good heart health may help protect you against Alzheimer's disease and other types of dementia, a new study suggests. Vanderbilt University researchers analyzed data from just over 1,000 people who were followed for 11 years. During that time, 32 participants developed dementia, including 26 with Alzheimer's. People with poorer heart function were two to three times more likely to develop dementia than those with healthy hearts, according to the study recently published online in the journal Circulation. "Heart function could prove to be a major risk factor for dementia and Alzheimer's disease," principal investigator Angela Jefferson, director of the Vanderbilt Memory and Alzheimer's Center, said in a university news release. "A very encouraging aspect of our findings is that heart health is a modifiable risk. You may not be able to change your genetics or ... Read more

Related support groups: Heart Disease, Dementia, Alzheimer's Disease, Ischemic Heart Disease

Many U.S. Households Include Someone With Failing Memory

Posted 5 Mar 2015 by Drugs.com

THURSDAY, March 5, 2015 – As many as one in eight U.S. households may have an adult with worsening memory loss or confusion, a new survey shows. These symptoms suggest a potential risk of developing more serious memory and thinking problems, such as Alzheimer's disease, the survey authors said. Further, a second study found that almost half of adults aged 45 and older who have experienced increasing memory loss or confusion reported that these problems have interfered with their daily life. And the youngest in this age group were the most likely to report these thinking declines. "Memory problems are typically one of the first warning signs of [thinking] decline," said Lynda Anderson, a co-author of the first study and lead author of the second study. She is director of the Healthy Aging Program at the U.S. Centers for Disease Control and Prevention. Noticing that others in the home ... Read more

Related support groups: Alzheimer's Disease

Gout's Silver Lining: A Lower Risk for Alzheimer's?

Posted 5 Mar 2015 by Drugs.com

THURSDAY, March 5, 2015 – The painful and often debilitating arthritic condition known as gout may offer patients an unexpected bonus: a lower risk for Alzheimer's disease. A new study finds that gout – or the high uric acid level that drives the inflammatory condition – may shield against the dementia. "Our work shows the potential protective effect of a high level of uric acid and gout against the development of Alzheimer's disease," said Dr. Hyon Choi, a professor of medicine in the division of rheumatology, allergy and immunology at the Massachusetts General Hospital and Harvard Medical School in Boston. The study comes after prior research that had suggested that people with gout might also have a lower risk for other neurodegenerative conditions such as Parkinson's disease. Still, the study can't prove cause-and-effect, and "this is just an initial finding," Choi added. "One ... Read more

Related support groups: Gout, Alzheimer's Disease

Brain Protein Tied to Alzheimer's Spotted in Young Adults

Posted 3 Mar 2015 by Drugs.com

MONDAY, March 2, 2015 – Brain plaque buildup, long linked to the onset of Alzheimer's disease, has been identified in the brains of men and women as young as 20, researchers say. "One thing this means is that the resource, the machinery, for making the clumps of plaque we see among Alzheimer's patients is already available in young individuals," said study co-author Changiz Geula, a research professor at the Northwestern University Feinberg School of Medicine in Chicago. "The implication appears to be that if we want to prevent these clumps from forming when a person becomes old, we may need to intervene much earlier than we have thought, to try and get rid of amyloid very early in life," Geula said. Geula and his colleagues analyzed brain tissue of 48 deceased people ranging in age from 20 to 99. At issue is an abnormal protein, or "amyloid," known to accumulate and surround ... Read more

Related support groups: Alzheimer's Disease

Skin Test for Alzheimer's, Parkinson's Shows Early Promise

Posted 24 Feb 2015 by Drugs.com

TUESDAY, Feb. 24, 2015 – A small, early study hints that a skin test may someday be able to help diagnose people with Alzheimer's and Parkinson's diseases. Researchers found that skin biopsies can reveal elevated levels of abnormal proteins associated with the two disorders. The study is being released ahead of its presentation in April at the annual meeting of the American Academy of Neurology (AAN) in Washington, D.C. As it stands now, a definite diagnosis of Alzheimer's disease in a living person has not been possible, so the illness is often "unrecognized until after the disease has progressed," Dr. Ildefonso Rodriguez-Leyva, of the Central Hospital at the University of San Luis Potosi in Mexico, explained in an academy news release. "We hypothesized that since skin has the same origin as brain tissue while in the embryo, that they might also show the same abnormal proteins," he ... Read more

Related support groups: Parkinson's Disease, Alzheimer's Disease

Use of Certain Allergy, Depression Meds Tied to Higher Odds for Dementia

Posted 26 Jan 2015 by Drugs.com

MONDAY, Jan. 26, 2015 – Long-term and/or high-dose use of a class of medications used for hay fever, depression and other ills has been linked in a new study to a higher risk of dementia. The drugs – called anticholinergics – include nonprescription diphenhydramine (Benadryl) and tricyclic antidepressants like doxepin (Sinequan). This class of medications also includes older antihistamines like chlorpheniramine (Chlor-Trimeton) and "antimuscarinic" drugs for bladder control, such as oxybutynin (Ditropan). However, the study could only point to an association between long-term or high-dose use of these drugs and a higher risk of dementia, it could not prove cause-and-effect. Also, the relationship "did not occur at the lowest dosage range but did occur at higher dosages used long-term," said one expert, Dr. Alan Manevitz, a clinical psychiatrist at Lenox Hill Hospital in New York ... Read more

Related support groups: Prozac, Celexa, Citalopram, Fluoxetine, Benadryl, Dementia, Claritin, Loratadine, Diphenhydramine, Alzheimer's Disease, Oxybutynin, Doxepin, Chlorpheniramine, Ditropan, Oxytrol, Silenor, Benadryl Allergy, Sarafem, Simply Sleep, Gelnique

Leaks in Brain May Contribute to Dementia

Posted 21 Jan 2015 by Drugs.com

WEDNESDAY, Jan. 21, 2015 – Age-related blood vessel leaks in the brain may contribute to the development of Alzheimer's disease and other types of dementia, according to a new study. The findings suggest it may be possible to use brain scans to detect such leaks and repair them in order to prevent damage that can lead to dementia, the University of Southern California researchers said. The investigators analyzed contrast-enhanced brain images from 64 people of various ages and found that the brain's protective blood barrier becomes leaky with age. This leakage begins in the hippocampus, an important learning and memory center damaged by Alzheimer's disease. "This is a significant step in understanding how the vascular system affects the health of our brains," said lead investigator Dr. Berislav Zlokovic, director of the Zilkha Neurogenetic Institute at the university's Keck School of ... Read more

Related support groups: Dementia, Alzheimer's Disease

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