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Asthma Treatments Fail Older Patients More Often: Study

Posted 12 Jun 2015 by

FRIDAY, June 12, 2015 – Asthma treatments, especially inhaled corticosteroids, are less likely to work for older patients, a new study suggests. Researchers looked at 1,200 patients with mild-to-moderate asthma, and found that treatment failure occurred in about 17 percent of those aged 30 and older, compared with about 10 percent of those younger than 30. Lower lung function and having asthma for a longer time were associated with a higher risk of treatment failure. When the researchers focused on specific therapies, they found that treatment failure increased consistently for every year above age 30 among patients who used inhaled corticosteroids. Patients aged 30 and older who used inhaled corticosteroids, either alone or in combination with other therapies, were more than twice as likely to have treatment failure than those younger than 30, the investigators found. Men and women ... Read more

Related support groups: Asthma, Albuterol, Symbicort, Spiriva, Asthma - Maintenance, Ventolin, Advair Diskus, Asthma - Acute, Advair HFA, Combivent, Epinephrine, Xopenex, Dulera, ProAir HFA, Theophylline, Ipratropium, Proventil, Atrovent, EpiPen, Primatene Mist

Teva Announces FDA Approval of ProAir RespiClick

Posted 1 Apr 2015 by

JERUSALEM--(BUSINESS WIRE)--Apr. 1, 2015-- Teva Pharmaceutical Industries Ltd., (NYSE:TEVA) today announced that the U.S. Food and Drug Administration (FDA) has approved ProAir RespiClick (albuterol sulfate) inhalation powder, a breath-actuated, multi-dose, dry-powder, short-acting beta-agonist (SABA) inhaler for the treatment or prevention of bronchospasm in patients 12 years of age and older with reversible obstructive airway disease; and for the prevention of exercise-induced bronchospasm (EIB) in patients 12 years of age and older. It is expected to become commercially available to patients during the second quarter of 2015. “ProAir RespiClick is the first and only breath-actuated, dry-powder rescue inhaler to be approved by the FDA for the treatment of acute asthma symptoms,” said Dr. David I. Bernstein of the University of Cincinnati College of Medicine, Division of Immunology, Al ... Read more

Related support groups: Asthma, Albuterol, Asthma - Acute

Few Parents Use Kids' Asthma Meds Correctly: Study

Posted 1 Nov 2013 by

FRIDAY, Nov. 1 – Most adults who help children take inhaled asthma medications don't know all of the steps involved for their proper use, new research finds. Using inhalers improperly often means a child receives too little medication, which can lead to continuing symptoms or worsening asthma, the study authors noted. "Of the 10 steps for accurate technique, we were surprised to learn that only one out of 169 caregivers knew all 10 steps," said study author Dr. Marina Reznik, an assistant professor of pediatrics at Albert Einstein College of Medicine in New York City. Reznik said the findings point to a need for better education when prescribing these asthma medications and devices, and she said it's important that health-care providers follow up with parents and caregivers at subsequent appointments to make sure the devices are being used correctly. Most asthma medications are ... Read more

Related support groups: Asthma, Albuterol, Symbicort, Ventolin, Fluticasone, Advair Diskus, Advair HFA, Qvar, Flovent, Budesonide, Xopenex, ProAir HFA, Entocort, Proventil, Entocort EC, Salmeterol, Beclomethasone, Pulmicort Flexhaler, Ventolin HFA, Proventil HFA

FDA Medwatch Alert: Albuterol Sulfate Inhalation Solution, 0.083 percent (Nephron Pharmaceuticals): Recall - Aseptic Processing Simulation Results

Posted 18 Oct 2013 by

ISSUE: Nephron Pharmaceuticals initiated a voluntary recall, at the retail level, of ten lots of product due to results from an internal monitoring process. NPC performs aseptic process simulation as part of an internal processes to assure product quality. All of the lots listed above met and passed NPC’s quality specifications at the time of manufacture. In accordance with published guidance regarding aseptic processing simulation from the FDA, NPC has initiated this recall as a precautionary measure. BACKGROUND: The affected product is identified as Albuterol Sulfate Inhalation Solution, 0.083%, in the 25 count packaging configuration (NDC# 0487-9501-25) and lots A3A33A, A3A33B, A3A34A, A3A35A, A3A36A, A3A37A, A3A38A, A3A40A, A3A41A, and A3A42A RECOMMENDATION: NPC is asking retailers to remove the affected lots from store shelves and is asking consumers to discontinue use and dispose ... Read more

Related support groups: Asthma, Albuterol, Ventolin, ProAir HFA, Proventil, Ventolin HFA, Proventil HFA, Volmax, Airet, Respirol, AccuNeb, Vospire ER

Certain COPD Meds Might Raise Heart Risks, Study Says

Posted 20 May 2013 by

MONDAY, May 20 – Long-acting inhaled medications used by millions of people with chronic obstructive pulmonary disease (COPD) may raise the risk of cardiovascular complications among older patients, a new large Canadian study reveals. The finding centers around patients over age 65 who are prescribed long-acting bronchodilators – either anticholinergics (such as Spiriva) or beta-agonists (such as Serevent). Both medications are commonly used to relieve the shortness of breath that characterizes moderate to severe COPD and to improve lung function. The team found that compared with patients who do not use either medication, those using either of these bronchodilators face a notably higher risk for experiencing a cardiac event, such as heart attack or heart failure. "The bad news is that, although everybody's different, there's a chance that by using these long-acting bronchodilators ... Read more

Related support groups: Chronic Obstructive Pulmonary Disease, Albuterol, Spiriva, Chronic Obstructive Pulmonary Disease, Maintenance, Ventolin, Epinephrine, Xopenex, ProAir HFA, Ipratropium, Proventil, Atrovent, EpiPen, Chronic Obstructive Pulmonary Disease, Acute, Primatene Mist, Salmeterol, Spiriva HandiHaler, Ventolin HFA, Tiotropium, Adrenalin, Maxair

Seniors Undertreated for Asthma, and Many Skip Inhalers: Study

Posted 1 May 2012 by

TUESDAY, May 1 – Asthma often is misdiagnosed and undertreated in older people, with only 53 percent of those with asthma using prescribed inhalers, a small new study suggests. The study included 77 people, including people both with and without asthma, who were over age 60. Of those with asthma, 89 percent also had allergies to mold, animals or dust mites. The asthma patients were more likely than those without asthma to have hay fever, arthritis, diabetes, higher levels of pain and poor general health than those without asthma. The study appears in the May issue of the journal Annals of Allergy, Asthma & Immunology. "Those with asthma reported more infections, physician visits and impact on health, yet only half are regularly treating the disease," lead author and allergist Dr. Andrew Smith said in a journal news release. "Patients should regularly carry and take prescribed asthma ... Read more

Related support groups: Asthma, Albuterol, Spiriva, Symbicort, Asthma - Maintenance, Ventolin, Fluticasone, Advair Diskus, Advair HFA, Asthma - Acute, Qvar, Flovent, Combivent, Epinephrine, Budesonide, Xopenex, Dulera, ProAir HFA, Mometasone, Entocort

Some Schools Don't Let Kids Carry Asthma Inhalers

Posted 27 Apr 2012 by

FRIDAY, April 27 – Although all 50 states have laws that allow children with asthma to carry inhalers at school and 48 states have laws that let youngsters carry epinephrine pens for serious allergies, experts say that some kids are still being denied access to these lifesaving medications during the school day. "Every school district handles this a little bit different, and for those who don't allow children to carry their medications, I think may be due to a lack of knowledge. School officials may not appreciate the risk that having epinephrine pens and inhalers in a locked office, instead of with the child, can pose," said Maureen George, an assistant professor at the University of Pennsylvania School of Nursing in Philadelphia. "Fewer than 200 children die each year from asthma in the U.S. That number is low, but those deaths are preventable. And it's a double tragedy when you lose ... Read more

Related support groups: Asthma, Albuterol, Ventolin, Epinephrine, Xopenex, ProAir HFA, Anaphylaxis, Proventil, EpiPen, Primatene Mist, Salmeterol, Ventolin HFA, Adrenalin, Terbutaline, Maxair, Proventil HFA, Alupent, Brovana, Formoterol, Maxair Autohaler

Rapid Asthma Treatment in ER May Prevent Admission

Posted 6 Apr 2012 by

FRIDAY, April 6 – Rapid treatment with asthma medications seems to help reduce hospitalizations among children with asthma, a new study finds. Canadian researchers analyzed data from 406 children and found that those with moderate or severe asthma attacks who received systemic corticosteroids within 75 minutes of arriving at a hospital emergency department were 16 percent less likely to be admitted to the hospital. Corticosteroids reduce inflammation. The findings illustrate the importance of rapidly identifying and treating children with asthma when they arrive at an emergency department, the researchers said. The study was recently published online in the journal Annals of Emergency Medicine. "We knew that corticosteroids could help avoid hospital admissions and relapses. However, just how delays between emergency department admission and administration of the treatment impacted ... Read more

Related support groups: Asthma, Albuterol, Spiriva, Symbicort, Ventolin, Fluticasone, Advair Diskus, Advair HFA, Asthma - Acute, Qvar, Flovent, Combivent, Epinephrine, Budesonide, Xopenex, Dulera, ProAir HFA, Mometasone, Entocort, Ipratropium

High Out-of-Pocket Costs for Kids' Asthma Drugs Could Pose Dangers

Posted 27 Mar 2012 by

TUESDAY, March 27 – When health insurers require parents to pay a larger share of the cost of asthma medications for their children, more kids need emergency asthma treatment, suggests new research. For children older than 5, higher out-of-pocket costs results in a small reduction in medication use and greater rates of hospitalization for asthma complications, the study found. "Asthma is the most common chronic disease in children. We looked at adherence to asthma medications that are intended to be taken year-round to prevent exacerbations [flare-ups]," said one of the study's authors, Dr. Anupam Jena, a physician at Massachusetts General Hospital and Harvard Medical School and a senior fellow at the Schaeffer Center for Health Policy and Economics at the University of Southern California. Jena said that adherence rates for these medications – the rate at which patients stick to ... Read more

Related support groups: Asthma, Singulair, Albuterol, Asthma - Maintenance, Ventolin, Fluticasone, Asthma - Acute, Flovent, Montelukast, ProAir HFA, Mometasone, Proventil, Ventolin HFA, Asmanex Twisthaler, Proventil HFA, Flovent HFA, Flovent Diskus, Volmax, Airet, Respirol

Asthma Meds Likely Safe During Pregnancy: Study

Posted 20 Jan 2012 by

FRIDAY, Jan. 20 – A new study found no statistically significant link between asthma medication use during pregnancy and common birth defects. However, the study did find a positive association between some rare birth defects and mothers with asthma, and potentially with their medication use. But, the researchers couldn't tease out whether the problem was a loss of oxygen from less than well-controlled asthma or an effect of medications. "Worsening asthma is a risk to the mom and the fetus. Hypoxia (a lack of oxygen) we know is a problem for a developing fetus. And, the potential risk they found here is very small. Even if it turns out to be a true increase, the risk is so small. This study raises more questions than it answers," said Dr. Natalie Meirowitz, chief of the division of maternal fetal medicine at Long Island Jewish Medical Center in New Hyde Park, N.Y. What's most ... Read more

Related support groups: Asthma, Albuterol, Spiriva, Symbicort, Asthma - Maintenance, Ventolin, Fluticasone, Advair Diskus, Advair HFA, Asthma - Acute, Qvar, Flovent, Combivent, Epinephrine, Budesonide, Xopenex, Dulera, ProAir HFA, Mometasone, Entocort

Study Offers Clues to Why Some Don't Benefit From Asthma Drugs

Posted 6 Jan 2012 by

FRIDAY, Jan. 6 – Almost half of patients with mild or moderate asthma may have a different type of disease than those with more severe symptoms, perhaps explaining why common treatments don't work well for them, new research suggests. "We are beginning to understand that different 'flavors' of asthma probably have different molecular mechanisms," said Dr. John Fahy, director of the Airway Clinical Research Center at the University of California, San Francisco. He is the senior author of the new study, published online Friday in the American Journal of Respiratory and Critical Care Medicine. Asthma is a chronic disease involving inflamed airways. As the airways become more swollen, the muscles around them can tighten when something triggers symptoms such as coughing, wheezing and shortness of breath. Current anti-inflammatory treatments target a condition called eosinophilic airway ... Read more

Related support groups: Asthma, Albuterol, Asthma - Maintenance, Triamcinolone, Ventolin, Fluticasone, Asthma - Acute, Qvar, Flovent, Epinephrine, Budesonide, Xopenex, ProAir HFA, Mometasone, Entocort, Proventil, EpiPen, Entocort EC, Primatene Mist, Salmeterol

Drug for Acute Respiratory Distress May Do More Harm Than Good: Study

Posted 12 Dec 2011 by

SUNDAY, Dec. 11 – A study assessing intravenous infusion of the drug salbutamol in patients with acute respiratory distress syndrome was halted because the treatment did not improve patient outcomes and was associated with an increased risk of death, researchers say. Acute respiratory distress syndrome (ARDS) occurs in about 14 percent of patients who require being placed on mechanical ventilation. The death rate among patients with ARDS is high – 40 to 60 percent – and survivors have a substantial decrease in their quality of life. However, "routine use of [beta-2] agonist therapy in mechanically ventilated patients with ARDS cannot be recommended," the researchers wrote in an article published in the Dec. 12 online edition of The Lancet. The British study included 326 patients who received either salbutamol (also known as albuterol) or a placebo within 72 hours of developing ARDS, ... Read more

Related support groups: Albuterol, Ventolin, ProAir HFA, Proventil, Ventolin HFA, Proventil HFA, Respiratory Distress Syndrome, Volmax, Airet, Respirol, AccuNeb, Vospire ER

Use of Asthma Controller Meds on the Rise Among U.S. Kids

Posted 13 Oct 2011 by

THURSDAY, Oct. 13 – The percentage of children with asthma in the United States who use a prescription "controller" medicine has nearly doubled since the late 1990s, a new federal government report finds. The analysis of data from the Medical Expenditure Panel Survey showed that the use of controller drugs by these children increased from 29 percent in 1997-1998 to 58 percent in 2007-2008, according to the latest News and Numbers from the U.S. Agency for Healthcare Research and Quality. Asthma controller drugs include: corticosteroids, which control inflammation and reduce the risk of airway spasms; beta-2-agonists, which make breathing easier; and leukotrienes, which help prevent asthma symptoms from occurring. Use of inhaled corticosteroids among American children with asthma increased from 15.5 percent to 40 percent, use of leukotrienes rose from 3 percent to 34 percent, and use of ... Read more

Related support groups: Asthma, Singulair, Albuterol, Asthma - Maintenance, Triamcinolone, Ventolin, Fluticasone, Qvar, Flovent, Epinephrine, Montelukast, Budesonide, Xopenex, ProAir HFA, Mometasone, Entocort, Proventil, EpiPen, Entocort EC, Primatene Mist

Hospitalized Kids May Receive Up to 35 Meds a Week

Posted 6 Sep 2011 by

TUESDAY, Sept. 6 – Some children, especially those with rare conditions, receive many different drugs while in the hospital, a new study finds. Acetaminophen, albuterol and antibiotics were the drugs most commonly given to hospitalized children, the researchers said. They also found an association between length of hospital stay and the number of drugs given to children. On the first day in children's hospitals, patients younger than 1 year at the 90th percentile of daily medication use received 11 drugs and those 1 year or older received 13 drugs. In general hospitals, patients younger than 1 year received 8 drugs and those 1 year or older received 12 drugs. By the seventh day of hospitalization in children's hospitals, patients younger than 1 year at the 90th percentile of total use of different medications had received 29 drugs and patients 1 year and older had received 35 drugs. In ... Read more

Related support groups: Tylenol, Acetaminophen, Albuterol, Paracetamol, Ventolin, ProAir HFA, Panadol, Proventil, Ventolin HFA, Tylenol Extra Strength, Proventil HFA, Panadol Osteo, Q-Pap, Tylenol Arthritis Caplet, Childrens Tylenol, Lemsip Max, Acetaminophen Quickmelt, Panamax, Q-Pap Extra Strength, Altenol

Excessive Heat Can Harm Medications, Expert Says

Posted 22 Aug 2011 by

SATURDAY, Aug. 20 – Medications can be harmed by high temperatures, say pharmacists. Although just a handful of drugs have been tested at temperatures above 86F, all medications could be altered by extreme heat, they warn. According to Dr. Amy Peak, clinical pharmacist and director of Drug Information Services at Butler University, several medications have been tested at high temperatures. She outlined some of the changes the researchers found: Albuterol inhalers: The container could burst at temperatures above 120F. Moreover, when stored at high temperatures, there may be a decrease in the amount of medication inhaled. Concentrated epinephrine: Cyclical heating could reduce 64 percent of the medication's potency. Diazepam: Concentration of this drug dropped 25 percent when stored at 98.6F. Formoterol (capsules that are placed in inhalers): Following four hours of exposure to 158F ... Read more

Related support groups: Ativan, Valium, Lorazepam, Insulin, Diazepam, Albuterol, Ventolin, Epinephrine, Dulera, ProAir HFA, Proventil, EpiPen, Primatene Mist, Ventolin HFA, Adrenalin, Proventil HFA, Formoterol, Foradil Aerolizer, EpiPen 2-Pak, Primatene Mist Inhaler

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Chronic Obstructive Pulmonary Disease, Acute, Asthma - Maintenance, Bronchospasm Prophylaxis, Asthma - Acute, Bronchiectasis, Chronic Obstructive Pulmonary Disease, Maintenance

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Ventolin, ProAir HFA, Proventil, Ventolin HFA, Proventil HFA, Volmax, AccuNeb, ProAir RespiClick, Vospire ER, Respirol, Airet

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