Does Otezla cause scalp thinning? I have been plagued by psoriasis. I get like concrete build up in circles all over my head. I started taking Otezla about 3 1/2 months ago. I also have MS. About a month ago of Otezla and tacrolimus cream the concrete started going away. I still have it a little. My scalp and my hair are also thinning. I am switching to Skyrizi once my insurance approves and my blood work comes back but until then, I have like 5 sites where I get lesions and Psoriatic arthritis. I am wondering if the scalp thinning is because I also have MS?