Has anyone had success with phentermine (adipex) in the past and then also had success with this drug after? I lost 25pd on phentermine a few years ago but have since gained it back. I tried going back on it a year ago but it didn't work. I am reluctant to get on Qysmia since the phentermine didn't work the last time I tried it. I am currently on Contrave and I am having terrible side effects; headache and motion sickness so I am stopping it. Only side effects I had on phentermine were insomnia and dry mouth. I took an over the counter sleep aid and that helped.