What is the protocol for using niacin for depression, and how quickly does it work?

I have used Niacin for quite some time (3-4 years). I don’t use it for depression, though. If, it, indeed, helps with depression, I have not noticed a difference. If you buy the capsules, take one per day. If you have the powder, 1/2 teaspoon per day. If you want to have a higher dose, I suggest that you talk to your doctor first. I take it for vascular circulation, and it also helps me control my weight/digestive system. Niacin also is supposed to be an anti-aging agent, keeping your skin looking younger; it is found in some of my face creams. I just read that Niacin protects you from free radicals as well as lowers cholesterol. You should take Vitamin C for fighting free radicals, if you don’t get enough in your diet (most people don’t). There’s also a brand for Niacin, Niacinamide, that doesn’t make you hot and sweaty. Good luck!