I went for a colonoscopy yesterday. All I can remember is screaming because of the horrific pain at the Propofol insertion site. The Dr. Told me there would be " a little burning"! Had I not fallen asleep I would have pulled the line out. I am not a baby with no pain tolerance, but this was unbelievable!!! I need to go for more surgery and almost want to cancel because of only ?30-40 seconds of barbaric pain. Actually I am embarrassed for screaming like that but I couldn't help it. Anyone experience this, or know why it would have been so bad?? Thank you
7 Aug 2013
Not sure of the "why" on your question, but I can tell you what to ask them to do differently. Most people experience a burning sensation, but not to the extend that you describe. If for future surgeries, the anesthesiologist/nurse anesthetist will be using propofol for general anesthesia, tell them about your painful experience with propofol. They can 1) mix lidocaine in with the propofol to be injected, or 2) Inject a dose of lidocaine into your IV line and allow it to circulate to "numb" or more like "desensitize" your vein before injecting the propofol. 3) In lieu of using lidocaine, the anesthesia folks can give you other sedations prior to induction of propofol so that you won't care if the propofol burns (to put it simply). They have ways to make your experience more comfortable. Best wishes for your future surgeries.
30 Aug 2013
Today, I had an endoscopy and underwent sedation with propofol. I experienced exactly the same thing that you described. The anesthetist told me to expect some burning but the sensation that I experience for those 15 seconds was the worse pain of my life. I also screamed so don't feel bad!
Good luck with the next procedure. Maybe ask them to try a little Lidocaine before or to use a mask induction.
31 Aug 2013
I experienced the same feeling with Phenergan the last time I was hospitalized. I had been vomiting for days and had yet to get PICC line, as my veins hardly last a minute. They had temporary IV in crook of wrist and the nurse told me it would burn, but she had to push it slow to avoid blowing the vein. I screamed so loud other nurses came running to my room to see what was wrong. To make matters worse, it continued to burn after she finished pushing as it had to make its way up the vein. After several hours and still no PICC line, had to get more Phenergan and that one blew the vein b4 it was all administered. I was at a supposedly "Full Service" hospital, but, unable to get a PICC line on weekend. Give me a break, for those of us with virtually NO good veins left, every minute without a line can be horrible!!
16 Oct 2013
I just had my 9th Spinal epidural today, and I also experienced the same thing, prompting me to ask the anesthesiologist what was causing the burning sensation. He remarked that, "Propofol is very acidic and conflicts with the natural alkalinity of your body, therefore the increase in pH causes said burning sensation, that is until you're completely unconscious lol." Hope that helped :)
23 Oct 2014
I work in a GI clinic. I have been giving anesthesia for many years. There is no excuse for you anesthesia provider not to give lidocaine prior to propofol.
Propofol burns like fire.
They only reason I can think of, for lidocaine not being given, is the provider was to lazy to draw it up. This makes me very angry! I try to treat my patients, like I would want my family treated. I am so sorry for this bad experience. There is no excuse for it, and this pain could have been prevented!!
11 Mar 2015
I had a very similar experience today during my colonoscopy. They always have trouble finding my veins, so when trying the IV they stuck me completely in two different places on my right arm and naturally put the bp cuff on the left arm. They later had to end up switching to a wrist IV on my left arm, I told them I didn't mind.
They finish and wheel me in for the procedure, and tell me they are ready for the sedative and I close my eyes and prepare myself for the "slight burn" they said would come. And right then my bp cuff inflates.
The sedative hits my veins in my arm and my whole arm is on fire. Like blowtorch to my skin fire. And I clench my eyes and wait a few seconds for it to pass, and it doesn't. And I'm nearly screaming in agony, starting to roll around on the bed, and finally a nurse realizes my bp cuff is inflated and keeping the propofol in my arm instead of diffusing. I swear my arm was on fire with the most horrible pain I have ever felt in my life for at least a 40 seconds. After hearing lidocaine is commonly used to numb beforehand, I'm a little upset no one thought of that to begin with for me. Someone did an oops, and at the moment I wanted nothing more than to punch someone. And then I instantly fell asleep. Lol
- Propofol Information for Consumers
- Propofol Information for Healthcare Professionals (includes dosage details)
- Side Effects of Propofol (detailed)
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