Does monistat 1 ovule supposed to feel sore after the second day of using it?

Jenine2016; YES THIS IS VERY COMMON. FOR A DAY OR TWO THE BURNING AND ITCHING. EFFECT. as it works on the bacteria or yeast. also make sure no sex for a week or so from the time you inserted the monistat 1, It could cause condom's or Diahphrams to not be as effective. So be careful. here are some of the effects to look for this info is off of our web site at drugs.com. hope this helps you and not to worry about the irritation for now if it gets to bad see the doctor. or talk with your Pharmacist. (((Possible side effects of Monistat-1:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild vaginal burning, irritation, or itching.
Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever or chills; foul-smelling vaginal discharge; nausea; severe or prolonged vaginal burning, irritation, or itching; stomach pain; vomiting.

This is not a complete list of all side effects that may occur.
So your in good shape for now. have a good weekend