11 May 2011
The M366 is 7.5 mg hydrocodone with 325 mgs acetominophen (tylenol) while the M358 is 7.5 mgs hydrocodone with 500 mgs acetominophen. So the amount of opoid pain killer is the same, the difference lies in the amount of cutting agent, acetominophen. So the M358 is ever so slightly stronger, though in reality I doubt you'll notice much difference between the two.
Hope this helps.
12 Apr 2013
Which is stronger? They're the same. The m358 has slightly more poison in it with 500 milligrams of acetaminophen. The higher the dose of that the worse it is on your liver. If your doctor ever write you a script for such a drug, try and get the acetaminophen at the lowest possible dose. But the hydrocodone is what helps with pain.
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