The acute colitis began with 'blood dirhea'. I stopped taking Vesicare at that point. After two weeks, my doctor told me to resume taking the it, that the good it would do far out weighed any bad. I did, returned to work at Lowe's Home Improvement.. Each day at work I felt better and back to my old self. On the 5th day of work, we had a shortage of people to pull freight to the floor from receiving, so four of us were recruited. I pulled several heavy pallets of tile. The sixth day I was fine and felt great, moving around great. It was the 7th morning after returning to work that I couldn't hardly move to get out of bed. My right foot couldn't hold any weight, my joints were burning and screaming from my neck to my feet. I have never had arthritis, never had chronic pain until this 'acute' whatever it is, hit. From the time I strained on frieght, to the time this hit me, was about 36 hours. Could Vesicare have caused this acute onset of pain? It has gotten progressively worse over the last 2 days.