Isosorbide Mononitrate - what is the difference between isosorbide monnitrate & isosorbide dintrate?

Isosorbide mononitrate has one nirate group and isosorbide dinatrate has 2 nitro groups.
Sublingual isosorbide dinitrate and nitroglycerin are the two compounds used to treat acute angina.
Their those has to be increased sufficiently to be given in oral form in maintenance therapy as these are rapidly degraded by liver with very low bioavailability.
Isosorbide dinitrate is not degraded by liver and has bioavailability of 100% and so is used best in maintenance therapy.
Amyl nitrate inhaler is also available for acute angina.

Ismo (Isosorbide Mononitrate) tablets are indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

Isordil (isosorbide dinitrate) Titradose tablets are indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of immediate-release oral isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

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