i have been on methotrexate 10 mgs every 3 days for treatment of servere plaque psoriasis and i require fusion for a spinal problem. this will not be done unless i stop taking the methotrexate. what i need to know is how long will it take to be completely out of my system. i have been taking it for about 3 years on this dose. My liver tests have always been good and i'm in good health.
17 Sep 2009
The length of time it takes for a medicine to be out of ones system depends on it's elimination half life. It takes 5.5 half life's for a medicine to be totally eliminated.
Methotrexate has an elimination half life of 3 to 10 hours, therefore it will take approximately 55 hours (if we take the maximum time as 10 hours for the half life) i.e. about 2.3 days for it to be totally out of your system.
- Methotrexate Information for Consumers
- Methotrexate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methotrexate (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
if i stop takeing two weeks befor i go on holiday would it be safe you have a drink?
1 answer • 24 Mar 2010
Hello All . I posted a question about My Psoriasis. I am a long psoriasis suffering pt. I am currently on Methotrexate. Im am on 9pills a week. But ...
5 answers • 8 Jul 2011
... arthritis. My friend said they haven't ever given it SQ it has always been given IM. Does anyone no if this is true
3 answers • 19 Jul 2011
... topicalls have failed(unsure that it wasn't because he didn't apply as directed). I am so scared this isn't the right choice... ...
1 answer • 13 Aug 2013
2 answers • 18 Sep 2013