i have been on methotrexate 10 mgs every 3 days for treatment of servere plaque psoriasis and i require fusion for a spinal problem. this will not be done unless i stop taking the methotrexate. what i need to know is how long will it take to be completely out of my system. i have been taking it for about 3 years on this dose. My liver tests have always been good and i'm in good health.
17 Sep 2009
The length of time it takes for a medicine to be out of ones system depends on it's elimination half life. It takes 5.5 half life's for a medicine to be totally eliminated.
Methotrexate has an elimination half life of 3 to 10 hours, therefore it will take approximately 55 hours (if we take the maximum time as 10 hours for the half life) i.e. about 2.3 days for it to be totally out of your system.
- Methotrexate Information for Consumers
- Methotrexate Information for Healthcare Professionals (includes dosage details)
- Side Effects of Methotrexate (detailed)
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