Hello! I have recently started taking 25mg of Zoloft for my anxiety and panic attacks.I know it takes a while to kick in but has anyone else gotten really irritable and just been really scared since they started taking it. I'm sure the fact that I am on something scares me more then anything else and doesn't help the situation. But I haven't experienced any other side effects except really strong bursts of irritability and fear. Did this happen to anyone else? Thanks
Zoloft - what side-effects did you experience?
Question posted by anonymous986 on 25 July 2010
Last updated on 4 April 2022 by careernavygirl
30 Answers
When I had a reaction to Zoloft I was told to stop taking it immediately and they scheduled me an appointment to see the Dr in the am. I had a different type of reaction though. Zoloft made my skin itch really bad.
I have recently started taking Zoloft ( Generic ) about 10 days ago and started at 25mg for 7 days then went up to 50mg but right away i started having side effects, nausia, dry mouth, Insomnia, loss of appetite, so i told my doctor and he told me to keep taking the 25mg for now i hope this will be ok. i also am scared of taking drugs and feeling foggy, sleepy, jittery, but i have to try something and its nice to know im not alone. good luck and god bless
I found that Zoloft really sends me up into the rafters! It's really got a manic inducing effect on me, which is really bad, I have shcizzo-effective disorder. This is a combination of being severely Bi-Polar, and mood fluctuations, with Paranoid Scizzephrenia with lack of sleep will cause a Psychotic Episode. I have had four major episodes with total break from reality, found out of my home naked, and had to be put in restraints! Zoloft started very soon to cause Manic states and caused the fear that I would not ever get to sleep if it kept increasing. If I cross a 72 hour threshold without sleep, i will be Psychotic. I think Zoloft is seriously damaging to the sex functions of normal achievement of orgasms. I stopped it for good!
I am currently on 100 mg of Zoloft and I have lost 19lbs in 35 days... I have more frequent bowel movements, I don't get hungry and when I do I get full fast... I sweat like a hog, have lil memory gaps, like I lose my lighter 3xs a week... If your scared or irritated you should talk to your doctor because I was having those effects on celexa and let me just say it didn't work out, my doctor wanted to keep me on it but I had a lil meltdown and the psych hospitals dr took me off it.. :) hope it helps at least a lil!
Hi ktneal,
I am having symptoms on Zoloft which are very similar to what you had. I have been on 50mg for 3 weeks now. The vagueness and memory gaps are what is worrying me the most. I have the common stuff too like loss of libido. Given your post is quite a long time ago, did you get thru the symptoms ?. I need to decide if I try yet another drug and trudge through the waiting period and pain of not being myself whilst I see if yet another one works. I appreciate your feedback. Cheers
I have severe PTSD as a 100% service-connected trauma injury veteran. The process for a multitude of drug therapies over many years, for me, has been trial & re-try until "your dose & meds" are balanced for you. Does take patience & persistence to get there but so well worth the journey! 25mg of Zoloft is below most therapeutic levels. Your anxiety is better served with other
meds and must be balanced with behavioral (not analysis) therapy to reduce the cause & effect of body/mind/spirit balance. Zoloft is not my anxiety med! I have taken Klonepin for years with no addication issues or prescription changes but it has saved my life, literally. I have appreciated the foundation these meds have given me, like a platform for slow clarity. We still need to learn how we can manage (or leave) our past behind. Best wishes to you. Just my own story,and personal opinions.
Hello, I was on Zoloft 25 mg for about 1 month, then increased to 50 mg for about 3 months until they put me on different medication to treat my other symptoms that were more concerning. This medication worked great for my anxiety. The only thing, like you said, at first when I started it I was scared to take it because I did not know what it was going to do which gave me anxiety. A few weeks into it my anxiety was 100x better. However, when they slowly took me off of it, by the time I was off my anxiety seemed worse than ever. I do not know if this was because of my schizophreniform that was diagnosed while of Zoloft (which is why they took me off) or if it had anything to do with the medication. I also noticed that I was more irritable around the time that I started taking it but that has not stopped since I switched from Zoloft to Resperidone so I do not know if that had anything to do with the medication either. Sorry for not having much information but I hope I helped a little.
Hi anonymous
Yes I did experience some of the same side effects like being irritable, scared and weak but it got better as my body got use to the Zoloft. Compare to other antidepressants I had the least side effects on Zoloft.
I hope you are doing well.
Dream
Hi, 10 years ago I was put on zoloft for anxiety and depression and only took it for three months.
I had severe heart burn that would not go away and I also experienced panic attacks.
I think though every person is affected differently by every medication.
Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults especially within the first few months of treatment. Depression and certain other serious mental illnesses are important causes of suicidal thoughts and actions. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior..
I actually was on that for a while, and I had a HORRIBLE reaction to it. Later I found out that I'm allergic to that category of drugs, so I'm slightly biased here, but I don't think zoloft is the solution for anxiety/panic attacks. I too suffer from those, and I have tried about 15 different meds for it, so I feel like my opinion might help. So far the only drug that has helped me is klonopin, the orally disintegrating ones are the best. They work very quickly, so if you feel like you're about to have an attack, you can just take one and about 10 min later you'll feel fine (so you completely avoid any attacks). Also compared to xanax and ativan there are fewer side effects. I highly recommend it, it really made me feel like myself again.
Also, I agree with what others are saying about how doctors like to try nonaddictive meds (like zoloft) first (that's the standard approach). But My doctor and I disagree with this method. The way my doctor stated it was, "you're taking a pill every day no matter what you're on, so does it really matter if you're technically 'addicted' to it? No matter what, you take it every day, and if you decide to go off of it, you can do it slowly with no withdrawal" And I think that makes a lot of sense. Maybe you could try explaining it to your doctor like that.
Years ago when I was first seeking help for panic attacks, anxiety and depression, I saw a psychiatrist who prescribed me Zoloft. It made me feel very sped up, like I was zipping through everything and my whole day. I was super alert, jittery, and everything seemed like it was going fast. That was all Zoloft ever did for me and I stopped taking it and never went back to that psychiatrist (she was weird, her place was weird, so yeah). I did not take it for long and I did not like the side effects.
What I might recommend is something like Valium or Xanax-XR. BUT, they cause dependency and can turn into a problem. I had a doctor prescribe me a low dose of Xanax-XR, but I did not get it every month, or a full 30 pills or anything. I kept a few on me in case of emergency and when I actually needed it. It also acted as a security blanket because I knew I had it with me if I began to feel overwhelmed or panicky, and simply knowing that eased my nerves and anxiety a lot and I really didn't take it that often.
Other than that, you might want to consider something like Celexa. From what I've heard and what doctors have told me, it is a great drug for panic and anxiety disorders. I hope you find something that works well for you.
In response to your question, my husband takes 100 mg of Zoloft for bipolar depression. He has not had these side effects. With your topic of PTSD, PD, SAD,& GAD, don't you think you could just have anxiety just taking a new med? If you are that uncomfortable you should speak with your doctor, but with all your problems I would suggest you give it some time to see if it can help you. It can take time for a med to work right, & usually they start at a lower dose & increase it slowly to get the maximum relief. Good luck...
I am going to be honest with you I was having terrible Panic at the time and I think the very fact that I was on something that I really didn't know much about really scared me, it didn't do anything for my anxiety or my panic, Zoloft was a drug that made me kind of jumpy and jittery, in all fairness to the drug a big part could have been me, I ended up being switched to another combination of Medications a 0.5 mg dose of xanax and Lexapro 10mg. those seemed to work but the one thing that I think is true for everyperson we are all unique and what drug may work for one person may be totally not the drug that works for another person, I think it is a matter of trial and error, I do understand what it feels like to go through anxiety and especially panic, it is a nightmare. I journaled every day I kept records of how each day went then when things weren't going well I could go back and see and sometimes I think it made me realize that things were not as bad as I always thought they were I wish you the very best
I began taking Zoloft at 10 years ago. My MD told me to ignore the side effects for the first couple of weeks. I had some intestinal upset at first but the major side effect was an overwhelming sense of feeling wiped out for a few days. All of my years of hyper active anxiety driven mental and physical life came down heavily.I felt like I couldn't get out of bed. This and the other more overt first reactions to the drug gradually disappeared. The gradual but longer lasting sexual dysfunction has persisted and I'm presently looking for options to correct this, if possible.
Being concerned about "being on something" went on for a number of years in one fashion or another. Thoughts that I was "cheating" and that I "should" or "ought" to do life without the drug were common. These thoughts were rooted in some hypothetical model of behavior with which I used to compare myself and ultimately stopped believing as true for me.
Now, if I could stop believing one thought... hmmmmm
Best wishes
I did!!! I don't know I couldn't stand the bursts of irritability and fear I was changed to Lexapro whatever they give you the one thing you have to do is fight, fight, fight, medications help but they don't stop it all please take care and above all be safe you may need to talk with the doctor
Related topics
zoloft, post traumatic stress disorder, anxiety, panic disorder, social anxiety disorder, generalized anxiety disorder
Further information
- Zoloft uses and safety info
- Zoloft prescribing info & package insert (for Health Professionals)
- Side effects of Zoloft (detailed)
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